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Results: 109
Subtype-specific micro-RNA expression signatures in breast cancer progression.
Vilde D Haakensen, Vegard Nygaard, Liliana Greger, Miriam R Aure, Bastian Fromm, Ida RK Bukholm, Torben Lüders, Suet-Feung Chin, Anna Git, Carlos Caldas, Vessela N Kristensen, Alvis Brazma, Anne-Lise Børresen-Dale, Eivind Hovig, Åslaug Helland
Aug 09, 2016
DCIS biomarker breast cancer invasion miRNA subtype Biomarkers Tumor Breast Neoplasms Carcinoma Ductal breast Carcinoma Intraductal Noninfiltrating Chromosome Mapping Cluster Analysis Disease Progression Female Gene Expression Profiling Gene Expression Regulation Neoplastic Humans MicroRNAs Multigene Family Neoplasm Invasiveness Reproducibility of Results Transcriptome
Contrasting Instructional Technology Adoption in K-12 Education to Promote Digital Equity
This quantitative study examined the frequency of usage and teacher perception of educational technology by K - 12 public school teachers in three geographic settings: urban, rural, and suburban. The objective aimed to uncover...
Published by: IGI Global Scientific Publishing
AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions
Abstract: AMPA receptor (AMPAR) abundance and positioning at excitatory synapses regulates the strength of transmission. Changes in AMPAR localisation can enact synaptic plasticity, allowing long-term information storage, and is...
AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions.
AMPA receptor (AMPAR) abundance and positioning at excitatory synapses regulates the strength of transmission. Changes in AMPAR localisation can enact synaptic plasticity, allowing long-term information storage, and is therefore...
Buffering noise
KAT2A is a histone acetyltransferase recently identified as a vulnerability in at least some forms of Acute Myeloid Leukemia (AML). Its loss or inhibition prompts leukemia stem cells out of self-renewal and into differentiation...
Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics.
Danyang Zhang, Remigijus Lape, Saher A Shaikh, Bianka K Kohegyi, Jake F Watson, Ondrej Cais, Terunaga Nakagawa, Ingo H Greger
Apr 17, 2023
AMPA glutamate receptors (AMPARs) mediate excitatory neurotransmission throughout the brain. Their signalling is uniquely diversified by brain region-specific auxiliary subunits, providing an opportunity for the development of...
Published by: Nature Communications
Computational Linguistic and SNA to Classify and Prevent Systemic Risk in the Colombian Banking Industry
The banking sector has been one of the first to identify the importance of social media analysis to understand customers' needs to offer new services, segment the market, build customer loyalty, or understand their requests....
Published by: IGI Global Scientific Publishing
Emergence and Structuring of the Clean Energy Regime Complex
While many have observed a regime complex for global clean energy governance, research has not yet accorded sufficient attention to the interplay of multiple streams of politics that have led to the structuring of overlapping...
The Data Journalism Handbook
Published by: O'Reilly Media
The decrease in silicon concentration of the connective tissues with age in rats is a marker of connective tissue turnover.
Silicon may be important for bone and connective tissue health. Higher concentrations of silicon are suggested to be associated with bone and the connective tissues, compared with the non-connective soft tissues. Moreover, in...
Mechanisms underlying TARP modulation of the GluA1/2-γ8 AMPA receptor.
Beatriz Herguedas, Bianka K Kohegyi, Jan-Niklas Dohrke, Jake F Watson, Danyang Zhang, Hinze Ho, Saher A Shaikh, Remigijus Lape, James M Krieger, Ingo H Greger
Feb 09, 2022
AMPA-type glutamate receptors (AMPARs) mediate rapid signal transmission at excitatory synapses in the brain. Glutamate binding to the receptor's ligand-binding domains (LBDs) leads to ion channel activation and desensitization....
Silicon and boron differ in their localization and loading in bone.
The Data Journalism Handbook
Published by: O'Reilly Media
Emergence and Structuring of the Clean Energy Regime Complex
While many have observed a regime complex for global clean energy governance, research has not yet accorded sufficient attention to the interplay of multiple streams of politics that have led to the structuring of overlapping...
Mechanisms underlying TARP modulation of the GluA1/2-γ8 AMPA receptor.
Beatriz Herguedas, Bianka K Kohegyi, Jan-Niklas Dohrke, Jake F Watson, Danyang Zhang, Hinze Ho, Saher A Shaikh, Remigijus Lape, James M Krieger, Ingo H Greger
Mar 13, 2022
AMPA-type glutamate receptors (AMPARs) mediate rapid signal transmission at excitatory synapses in the brain. Glutamate binding to the receptor's ligand-binding domains (LBDs) leads to ion channel activation and desensitization....
Inferring Allele Frequency Trajectories from Ancient DNA Indicates That Selection on a Chicken Gene Coincided with Changes in Medieval Husbandry Practices
Conducting Polymer-Ionic Liquid Electrode Arrays for High-Density Surface Electromyography.
Santiago Velasco-Bosom, Nuzli Karam, Alejandro Carnicer-Lombarte, Johannes Gurke, Nerea Casado, Liliana C Tomé, David Mecerreyes, George G Malliaras
May 03, 2021
Surface electromyography (EMG) is used as a medical diagnostic and to control prosthetic limbs. Electrode arrays that provide large-area, high density recordings have the potential to yield significant improvements in both...
Effects of Cannabis Use on the Protein and Lipid Profile of Olfactory Neuroepithelium Cells from Schizophrenia Patients Studied by Synchrotron-Based FTIR Spectroscopy.
Sergi Saladrigas-Manjón, Tanja Dučić, Liliana Galindo, Cristina Fernández-Avilés, Víctor Pérez, Rafael de la Torre, Patricia Robledo
Feb 20, 2020
Schizophrenia (SCZ) is a neurodevelopmental disorder with a high genetic component, but the presence of environmental stressors can be important for its onset and progression. Cannabis use can be a major risk factor for...
Fine-scale phylogeographic structure of <i>Borrelia lusitaniae</i> revealed by multilocus sequence typing
Liliana R Vitorino, Gabriele Margos, Edward J Feil, Margarida Collares-Pereira, Libia Zé-Zé, Klaus Kurtenbach
Jan 01, 0001
Borrelia lusitaniae is an Old World species of the Lyme borreliosis (LB) group of tick-borne spirochetes and prevails mainly in countries around the Mediterranean Basin. Lizards of the family Lacertidae have been identified as...
Quantitative Checklist for Autism in Toddlers (Q-CHAT). A population screening study with follow-up
Carrie Allison, Fiona E Matthews, Liliana Ruta, Greg Pasco, Renee Soufer, Carol Brayne, Tony Charman, Simon Baron-Cohen
Apr 30, 2021
OBJECTIVE: This is a prospective population screening study for autism in toddlers aged 18-30 months old using the Quantitative Checklist for Autism in Toddlers (Q-CHAT), with follow-up at age 4. DESIGN: Observational study....
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