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Results: 5
Germline Sequencing DNA Repair Genes in 5545 Men With Aggressive and Nonaggressive Prostate Cancer.
Burcu F Darst, Tokhir Dadaev, Ed Saunders, Xin Sheng, Peggy Wan, Loreall Pooler, Lucy Y Xia, Stephen Chanock, Sonja I Berndt, Susan M Gapstur, Victoria Stevens, Demetrius Albanes, Stephanie J Weinstein, Vincent Gnanapragasam, Graham G Giles, Tu Nguyen-Dumont, Roger L Milne, Mark Pomerantz, Julie A Schmidt, Lorelei Mucci, William J Catalona, Kurt N Hetrick, Kimberly F Doheny, Robert J Macinnis, Melissa C Southey, Rosalind A Eeles, Fredrik Wiklund, Zsofia Kote-Jarai, David V Conti, Christopher A Haiman
Sep 03, 2020
Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons.
Teresa Rodríguez-Martín, Amy M Pooler, Dawn HW Lau, Gábor M Mórotz, Kurt J De Vos, Jonathan Gilley, Michael P Coleman, Diane P Hanger
Jun 18, 2018
Expression of the frontotemporal dementia-related tau mutation, P301L, at physiological levels in adult mouse brain (KI-P301L mice) results in overt hypophosphorylation of tau and age-dependent alterations in axonal...
Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice.
Jonathan Gilley, Kunie Ando, Anjan Seereeram, Teresa Rodríguez-Martín, Amy M Pooler, Laura Sturdee, Brian H Anderton, Jean-Pierre Brion, Diane P Hanger, Michael P Coleman
Jun 18, 2018
Hyperphosphorylation and fibrillar aggregation of the microtubule-associated protein tau are key features of Alzheimer's disease and other tauopathies. To investigate the involvement of tau phosphorylation in the pathological...
GWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer.
Maxine M Chen, Tracy A O'Mara, Deborah J Thompson, Jodie N Painter, Australian National Endometrial Cancer Study Group (ANECS), John Attia, Amanda Black, Louise Brinton, Stephen Chanock, Chu Chen, Timothy Ht Cheng, Linda S Cook, Marta Crous-Bou, Jennifer Doherty, Christine M Friedenreich, Montserrat Garcia-Closas, Mia M Gaudet, Maggie Gorman, Christopher Haiman, Susan E Hankinson, Patricia Hartge, Brian E Henderson, Shirley Hodgson, Elizabeth G Holliday, Pamela L Horn-Ross, David J Hunter, Loic Le Marchand, Xiaolin Liang, Jolanta Lissowska, Jirong Long, Lingeng Lu, Anthony M Magliocco, Lynn Martin, Mark McEvoy, National Study of Endometrial Cancer Genetics Group (NSECG), Sara H Olson, Irene Orlow, Loreall Pooler, Jennifer Prescott, Radhai Rastogi, Timothy R Rebbeck, Harvey Risch, Carlotta Sacerdote, Frederick Schumacher, Veronica Wendy Setiawan, Rodney J Scott, Xin Sheng, Xiao-Ou Shu, Constance Turman, David Van Den Berg, Zhaoming Wang, Noel S Weiss, Nicholas Wentzensen, Lucy Xia, Yong-Bing Xiang, Hannah P Yang, Herbert Yu, Wei Zheng, Paul DP Pharoah, Alison M Dunning, Ian Tomlinson, Douglas F Easton, Peter Kraft, Amanda B Spurdle, Immaculata De Vivo
Apr 15, 2016
Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer.
Pik-Fang Kho, Frederic Amant, Daniela Annibali, Katie Ashton, John Attia, Paul L Auer, Matthias W Beckmann, Amanda Black, Louise Brinton, Daniel D Buchanan, Stephen J Chanock, Chu Chen, Maxine M Chen, Timothy Ht Cheng, Linda S Cook, Marta Crous-Bous, Kamila Czene, Immaculata De Vivo, Joe Dennis, Thilo Dörk, Sean C Dowdy, Alison M Dunning, Matthias Dürst, Douglas F Easton, Arif B Ekici, Peter A Fasching, Brooke L Fridley, Christine M Friedenreich, Montserrat García-Closas, Mia M Gaudet, Graham G Giles, Ellen L Goode, Maggie Gorman, Christopher A Haiman, Per Hall, Susan E Hankinson, Alexander Hein, Peter Hillemanns, Shirley Hodgson, Erling A Hoivik, Elizabeth G Holliday, David J Hunter, Angela Jones, Peter Kraft, Camilla Krakstad, Diether Lambrechts, Loic Le Marchand, Xiaolin Liang, Annika Lindblom, Jolanta Lissowska, Jirong Long, Lingeng Lu, Anthony M Magliocco, Lynn Martin, Mark McEvoy, Roger L Milne, Miriam Mints, Rami Nassir, Geoffrey Otton, Claire Palles, Loreall Pooler, Tony Proietto, Timothy R Rebbeck, Stefan P Renner, Harvey A Risch, Matthias Rübner, Ingo Runnebaum, Carlotta Sacerdote, Gloria E Sarto, Fredrick Schumacher, Rodney J Scott, V Wendy Setiawan, Mitul Shah, Xin Sheng, Xiao-Ou Shu, Melissa C Southey, Emma Tham, Ian Tomlinson, Jone Trovik, Constance Turman, Jonathan P Tyrer, David Van Den Berg, Zhaoming Wang, Nicolas Wentzensen, Lucy Xia, Yong-Bing Xiang, Hannah P Yang, Herbert Yu, Wei Zheng, Penelope M Webb, Deborah J Thompson, Amanda B Spurdle, Dylan M Glubb, Tracy A O'Mara
Sep 23, 2020
Blood lipids have been associated with the development of a range of cancers, including breast, lung and colorectal cancer. For endometrial cancer, observational studies have reported inconsistent associations between blood...