Search
Results: 4
Glyoxylate Metabolism in Mycobacterium smegmatis
Lubomir Nikolaev Merkov
Jan 01, 0001
Much has been learned about Mycobacterium tuberculosis, the causative agent of tuberculosis, âthe great white plague,â? since the bacterium was isolated and initially characterized by Robert Koch over a century ago. Over the...
Published by: Rockefeller University
cGMP-Elevating Compounds and Ischemic Conditioning Provide Cardioprotection Against Ischemia and Reperfusion Injury via Cardiomyocyte-Specific BK Channels.
Sandra Frankenreiter, Piotr Bednarczyk, Angelina Kniess, Nadja I Bork, Julia Straubinger, Piotr Koprowski, Antoni Wrzosek, Eva Mohr, Angela Logan, Michael P Murphy, Meinrad Gawaz, Thomas Krieg, Adam Szewczyk, Viacheslav O Nikolaev, Peter Ruth, Robert Lukowski
Dec 10, 2018
BACKGROUND: The nitric oxide-sensitive guanylyl cyclase/cGMP-dependent protein kinase type I signaling pathway can afford protection against the ischemia/reperfusion injury that occurs during myocardial infarction. Reportedly...
cyclic guanosine-3' 5'-monophosphate Ischemic Postconditioning Ischemic preconditioning Mitochondria Myocardial Infarction nitric oxide–sensitive guanylyl cyclase voltage and Ca2+-activated potassium channel BK Animals Benzoates Cardiotonic Agents Cyclic AMP-Dependent Protein Kinase Type I Disease Models Animal Humans Ischemic preconditioning Large-Conductance Calcium-Activated Potassium Channels Mice Mice 129 Strain Mice Inbred C57BL Mice Knockout Myocardial Infarction Myocardium Myocytes Cardiac Nitric oxide Pyrazoles Pyrimidines Reperfusion Injury
Vismodegib resistant mutations are not selected in multifocal relapses of locally advanced basal cell carcinoma after vismodegib discontinuation.
M Ighilahriz, M Benfodda, H Sharpe, N Soufir, S Mourah, N Dumaz, M Battistella, A Savina, F Bouquet, S Nikolaev, N Basset-Seguin
Jul 16, 2019
Hedgehog pathway inhibitors (HPI) inactivating SMO 1, have become first line treatment for patients with locally advanced BCC (laBCC). HPI safety and efficacy have been shown in clinical trials2,3. Nevertheless, common adverse...
GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation.
Makoto Shigeto, Reshma Ramracheya, Andrei I Tarasov, Chae Young Cha, Margarita V Chibalina, Benoit Hastoy, Koenraad Philippaert, Thomas Reinbothe, Nils Rorsman, Albert Salehi, William R Sones, Elisa Vergari, Cathryn Weston, Julia Gorelik, Masashi Katsura, Viacheslav O Nikolaev, Rudi Vennekens, Manuela Zaccolo, Antony Galione, Paul RV Johnson, Kohei Kaku, Graham Ladds, Patrik Rorsman
Nov 19, 2015