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Evaluation of RGD functionalization in hybrid hydrogels as 3D neural stem cell culture systems.
Emanuele Mauri, Alessandro Sacchetti, Nunzio Vicario, Luca Peruzzotti-Jametti, Filippo Rossi, Stefano Pluchino
May 21, 2018
The use of neural stem cells (NSCs) in cell therapy has become a powerful tool used for the treatment of central nervous system diseases, including traumatic brain and spinal cord injuries. However, a significant drawback is...
Analysis of simultaneous multielectrode recordings with 4,096 channels
Matthias H Hennig, Alessandro Maccione, Mauro Gandolfo, Matthew Down, Stephen J Eglen, Luca Berdondini, Evelyne Sernagor
Jul 22, 2011
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display...
Neurochemical Correlates of Brain Atrophy in Fibromyalgia Syndrome
Paola Feraco, Salvatore Nigro, Luca Passamonti, Alessandro Grecucci, Maria Eugenia Caligiuri, Cesare Gagliardo, Antonella Bacci
Jun 21, 2020
(1) Background: Recently, a series of clinical neuroimaging studies on fibromyalgia (FM) have shown a reduction in cortical volume and abnormally high glutamate (Glu) and glutamate + glutamine (Glx) levels in regions associated...
Correlates of the discrepancy between objective and subjective cognitive functioning in non-demented patients with Parkinson's disease.
Mattia Siciliano, Lugi Trojano, Rosa De Micco, Valeria Sant'Elia, Alfonso Giordano, Antonio Russo, Luca Passamonti, Gioacchino Tedeschi, Carlo Chiorri, Alessandro Tessitore
Mar 10, 2021
BACKGROUND: Subjective complaints of cognitive deficits are not necessarily consistent with objective evidence of cognitive impairment in Parkinson's disease (PD). Here we examined the factors associated with the...
Revisiting degron motifs in human AURKA required for its targeting by APC/CFZR1.
Ahmed Abdelbaki, Camilla Ascanelli, Cynthia N Okoye, H Begum Akman, Giacomo Janson, Mingwei Min, Chiara Marcozzi, Anja Hagting, Rhys Grant, Maria De Luca, Italia Anna Asteriti, Giulia Guarguaglini, Alessandro Paiardini, Catherine Lindon
Jan 04, 2023
Mitotic kinase Aurora A (AURKA) diverges from other kinases in its multiple active conformations that may explain its interphase roles and the limited efficacy of drugs targeting the kinase pocket. Regulation of AURKA activity...
Left egocentric neglect in early subacute right-stroke patients is related to damage of the superior longitudinal fasciculus.
Barbara Spanò, Davide Nardo, Giovanni Giulietti, Alessandro Matano, Ilenia Salsano, Chiara Briani, Rita Vadalà, Claudia Marzi, Maria De Luca, Carlo Caltagirone, Valerio Santangelo
Feb 09, 2022
A typical consequence of stroke in the right hemisphere is unilateral spatial neglect. Distinct forms of neglect have been described, such as space-based (egocentric) and object-based (allocentric) neglect. However, the...
Neurochemical Correlates of Brain Atrophy in Fibromyalgia Syndrome
Paola Feraco, Salvatore Nigro, Luca Passamonti, Alessandro Grecucci, Maria Eugenia Caligiuri, Cesare Gagliardo, Antonella Bacci
Sep 09, 2020
(1) Background: Recently, a series of clinical neuroimaging studies on fibromyalgia (FM) have shown a reduction in cortical volume and abnormally high glutamate (Glu) and glutamate + glutamine (Glx) levels in regions associated...
Correlates of the discrepancy between objective and subjective cognitive functioning in non-demented patients with Parkinson’s disease
Mattia Siciliano, Lugi Trojano, Rosa De Micco, Valeria Sant’Elia, Alfonso Giordano, Antonio Russo, Luca Passamonti, Gioacchino Tedeschi, Carlo Chiorri, Alessandro Tessitore
Aug 12, 2021
Abstract: Background: Subjective complaints of cognitive deficits are not necessarily consistent with objective evidence of cognitive impairment in Parkinson’s disease (PD). Here we examined the factors associated with the...
Left egocentric neglect in early subacute right-stroke patients is related to damage of the superior longitudinal fasciculus.
Barbara Spanò, Davide Nardo, Giovanni Giulietti, Alessandro Matano, Ilenia Salsano, Chiara Briani, Rita Vadalà, Claudia Marzi, Maria De Luca, Carlo Caltagirone, Valerio Santangelo
Jul 12, 2021
A typical consequence of stroke in the right hemisphere is unilateral spatial neglect. Distinct forms of neglect have been described, such as space-based (egocentric) and object-based (allocentric) neglect. However, the...
The Genetic Origin of Daunians and the Pan-Mediterranean Southern Italian Iron Age Context.
Serena Aneli, Tina Saupe, Francesco Montinaro, Anu Solnik, Ludovica Molinaro, Cinzia Scaggion, Nicola Carrara, Alessandro Raveane, Toomas Kivisild, Mait Metspalu, Christiana L Scheib, Luca Pagani
Feb 17, 2022
The geographical location and shape of Apulia, a narrow land stretching out in the sea at the South of Italy, made this region a Mediterranean crossroads connecting Western Europe and the Balkans. Such movements culminated at...
Validation of new diagnostic criteria for fatigue in patients with Parkinson disease.
Mattia Siciliano, Benzi Kluger, Rosa De Micco, Carlo Chiorri, Valeria Sant'Elia, Marcello Silvestro, Alfonso Giordano, Gioacchino Tedeschi, Luca Passamonti, Luigi Trojano, Alessandro Tessitore
Jun 07, 2022
BACKGROUND AND PURPOSE: Although disabling fatigue is common in Parkinson disease (PD), available consensus-based diagnostic criteria have not yet been empirically validated. The aim of this study was to evaluate the clinimetric...
The SIFIPAC/WSES/SICG/SIMEU guidelines for diagnosis and treatment of acute appendicitis in the elderly (2019 edition)
Paola Fugazzola, Marco Ceresoli, Vanni Agnoletti, Ferdinando Agresta, Bruno Amato, Paolo Carcoforo, Fausto Catena, Osvaldo Chiara, Massimo Chiarugi, Lorenzo Cobianchi, Federico Coccolini, Alessandro De Troia, Salomone Di Saverio, Andrea Fabbri, Carlo Feo, Francesco Gabrielli, Angela Gurrado, Angelo Guttadauro, Leonardo Leone, Daniele Marrelli, Luca Petruzzelli, Nazario Portolani, Francesco Paolo Prete, Alessandro Puzziello, Massimo Sartelli, Giorgio Soliani, Mario Testini, Salvatore Tolone, Matteo Tomasoni, Gregorio Tugnoli, Pierluigi Viale, Monica Zese, Offir Ben Ishay, Yoram Kluger, Andrew Kirkpatrick, Luca Ansaloni
Jun 06, 2020
Abstract: The epidemiology and the outcomes of acute appendicitis in elderly patients are very different from the younger population. Elderly patients with acute appendicitis showed higher mortality, higher perforation rate...
Transglutaminase 3 Reduces the Severity of Psoriasis in Imiquimod-Treated Mouse Skin.
Maria Cristina Piro, Alessandra Ventura, Artem Smirnov, Andrea Saggini, Anna Maria Lena, Alessandro Mauriello, Luca Bianchi, Gerry Melino, Eleonora Candi
May 15, 2020
Four transglutaminase (TG) isoforms have been detected in epidermal keratinocytes: TG1, TG2, TG3, and TG5. Except for TG1 and TG3, their contribution to keratinocyte development and structure remains undefined. In this paper, we...
The SIFIPAC/WSES/SICG/SIMEU guidelines for diagnosis and treatment of acute appendicitis in the elderly (2019 edition).
Paola Fugazzola, Marco Ceresoli, Vanni Agnoletti, Ferdinando Agresta, Bruno Amato, Paolo Carcoforo, Fausto Catena, Osvaldo Chiara, Massimo Chiarugi, Lorenzo Cobianchi, Federico Coccolini, Alessandro De Troia, Salomone Di Saverio, Andrea Fabbri, Carlo Feo, Francesco Gabrielli, Angela Gurrado, Angelo Guttadauro, Leonardo Leone, Daniele Marrelli, Luca Petruzzelli, Nazario Portolani, Francesco Paolo Prete, Alessandro Puzziello, Massimo Sartelli, Giorgio Soliani, Mario Testini, Salvatore Tolone, Matteo Tomasoni, Gregorio Tugnoli, Pierluigi Viale, Monica Zese, Offir Ben Ishay, Yoram Kluger, Andrew Kirkpatrick, Luca Ansaloni
Apr 11, 2020
The epidemiology and the outcomes of acute appendicitis in elderly patients are very different from the younger population. Elderly patients with acute appendicitis showed higher mortality, higher perforation rate, lower...
Published by: World journal of emergency surgery : WJES
mTORC1 Upregulation Leads to Accumulation of the Oncometabolite Fumarate in a Mouse Model of Renal Cell Carcinoma.
Luca Drusian, Elisa Agnese Nigro, Valeria Mannella, Roberto Pagliarini, Monika Pema, Ana SH Costa, Fabio Benigni, Alessandro Larcher, Marco Chiaravalli, Edoardo Gaude, Francesco Montorsi, Umberto Capitanio, Giovanna Musco, Christian Frezza, Alessandra Boletta
Nov 01, 2018
Renal cell carcinomas (RCCs) are common cancers diagnosed in more than 350,000 people each year worldwide. Several pathways are de-regulated in RCCs, including mTORC1. However, how mTOR drives tumorigenesis in this context is...
TCA cycle cancer metabolism cancer signaling epithelial transformation Fumarate Hydratase Metabolic reprogramming papillary carcinoma rapamycin renal cancer renal cysts Animals Carcinoma Renal Cell Cells Cultured Female Fumarate Hydratase Fumarates Humans Kidney Neoplasms Male Mechanistic Target of Rapamycin Complex 1 Mice Mice Inbred C57BL Tuberous Sclerosis Complex 1 Protein Up-Regulation
The SIFIPAC/WSES/SICG/SIMEU guidelines for diagnosis and treatment of acute appendicitis in the elderly (2019 edition).
Paola Fugazzola, Marco Ceresoli, Vanni Agnoletti, Ferdinando Agresta, Bruno Amato, Paolo Carcoforo, Fausto Catena, Osvaldo Chiara, Massimo Chiarugi, Lorenzo Cobianchi, Federico Coccolini, Alessandro De Troia, Salomone Di Saverio, Andrea Fabbri, Carlo Feo, Francesco Gabrielli, Angela Gurrado, Angelo Guttadauro, Leonardo Leone, Daniele Marrelli, Luca Petruzzelli, Nazario Portolani, Francesco Paolo Prete, Alessandro Puzziello, Massimo Sartelli, Giorgio Soliani, Mario Testini, Salvatore Tolone, Matteo Tomasoni, Gregorio Tugnoli, Pierluigi Viale, Monica Zese, Offir Ben Ishay, Yoram Kluger, Andrew Kirkpatrick, Luca Ansaloni
Mar 10, 2021
The epidemiology and the outcomes of acute appendicitis in elderly patients are very different from the younger population. Elderly patients with acute appendicitis showed higher mortality, higher perforation rate, lower...
Longitudinal RNA-Seq Analysis of Vertebrate Aging Identifies Mitochondrial Complex I as a Small-Molecule-Sensitive Modifier of Lifespan.
Mario Baumgart, Steffen Priebe, Marco Groth, Nils Hartmann, Uwe Menzel, Luca Pandolfini, Philipp Koch, Marius Felder, Michael Ristow, Christoph Englert, Reinhard Guthke, Matthias Platzer, Alessandro Cellerino
Mar 01, 2016
GAGE Nothobranchius furzeri RNA transport RNA-seq aging history trait hormesis hourglass life ribosome lifespan regulation longevity longitudinal study mitohormesis rejuvenation weighted gene coexpression network analysis (WGCNA) Zebrafish Animals Cyprinodontiformes Longitudinal Studies RNA Sequence Analysis RNA Vertebrates
A Digital Twin Approach for Selection and Deployment of Decarbonization Solutions for the Maritime Sector
Anargyros Mavrakos, Theodosis Tsaousis, Nicolo Faggioni, Alessandro Caviglia, Eros Manzo
Apr 09, 2024
Shipping decarbonisation is a challenge that can only be tackled by a holistic approach that combines advancements in technology, optimisation of the ship design, taking into account also the decarbonisation solutions...
Sustainable Development Business and Management Operations and Service Management Computer Science and Information Technology Life Sciences
Published by: IGI Global Scientific Publishing
Randomized Control Trial of Postnatal rhIGF-1/rhIGFBP-3 Replacement in Preterm Infants
Sandra Horsch, Alessandro Parodi, Boubou Hallberg, Mariya Malova, Isabella M Björkman-Burtscher, Ingrid Hansen-Pupp, Neil Marlow, Kathryn Beardsall, David Dunger, Mirjam van Weissenbruch, Lois EH Smith, Mohamed Hamdani, Alexandra Mangili, Norman Barton, Luca A Ramenghi, Ann Hellström, David Ley, ROPP-2008-01 Study Team
Nov 24, 2020
Background: Postnatal insulin-like growth factor-1 (IGF-1) replacement with recombinant human (rh)IGF-1 and IGF binding protein-3 (rhIGF-1/rhIGFBP-3) is being studied as a potential treatment to reduce comorbidities of...
Seagrass meadows (Posidonia oceanica) distribution and trajectories of change.
Luca Telesca, Andrea Belluscio, Alessandro Criscoli, Giandomenico Ardizzone, Eugenia T Apostolaki, Simonetta Fraschetti, Michele Gristina, Leyla Knittweis, Corinne S Martin, Gérard Pergent, Adriana Alagna, Fabio Badalamenti, Germana Garofalo, Vasilis Gerakaris, Marie Louise Pace, Christine Pergent-Martini, Maria Salomidi
Nov 23, 2015
fMRI evidence for areas that process surface gloss in the human visual cortex.
The Ethics of Astrobiology and the Cosmic Bet Argument
Luca Lo Sapio
Jan 01, 2024
Stephen Weinberg posited in 1977 that as the universe becomes more comprehensible, it appears more meaningless owing to a strict division between facts and values. He seemingly overlooked the consideration of the purposes and...
Published by: IGI Global Scientific Publishing
Selectivity-permeability optimization of functionalised CNT-polymer membranes for water treatment
Polymer membranes incorporating carbon nanotubes (CNT) belong to two broad categories: Vertically aligned (VA-CNT) membranes, where the polymer acts solely as a matrix embedding an aligned forest of nanotubes, and thin film...
K2-79b and K2-222b
Abstract
We present mass and radius measurements of K2-79b and K2-222b, two transiting exoplanets orbiting active G-type stars observed with HARPS-N and K2. Their respective 10.99...
Chantanelle Nava, Mercedes López-Morales, Annelies Mortier, Li Zeng, Helen AC Giles, Allyson Bieryla, Andrew Vanderburg, Lars A Buchhave, Ennio Poretti, Steven H Saar, Xavier Dumusque, David W Latham, David Charbonneau, Mario Damasso, Aldo S Bonomo, Christophe Lovis, Andrew Collier Cameron, Jason D Eastman, Alessandro Sozzetti, Rosario Cosentino, Marco Pedani, Francesco Pepe, Emilio Molinari, Dimitar Sasselov, Michel Mayor, Manu Stalport, Luca Malavolta, Ken Rice, Christopher A Watson, AF Martinez Fiorenzano, Luca Di Fabrizio
Jan 10, 2022
The VENUSS prognostic model to predict disease recurrence following surgery for non-metastatic papillary renal cell carcinoma
Tobias Klatte, Kevin M. Gallagher, Luca Afferi, Alessandro Volpe, Nils Kroeger, Silvia Ribback, Alan McNeill, Antony C. P. Riddick, James N. Armitage, Tevita F. ‘Aho, Tim Eisen, Kate Fife, Axel Bex, Allan J. Pantuck, Grant D. Stewart
Oct 02, 2020
Abstract: Background: The current World Health Organization classification recognises 12 major subtypes of renal cell carcinoma (RCC). Although these subtypes differ on molecular and clinical levels, they are generally managed...
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