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Results: 13107
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.
Parasvi S Patel, Karan Joshua Abraham, Kiran Kumar Naidu Guturi, Marie-Jo Halaby, Zahra Khan, Luis Palomero, Brandon Ho, Shili Duan, Jonathan St-Germain, Arash Algouneh, Francesca Mateo, Samah El Ghamrasni, Haithem Barbour, Daniel R Barnes, Jonathan Beesley, Otto Sanchez, Hal K Berman, Grant W Brown, El Bachir Affar, Georgia Chenevix-Trench, Antonis C Antoniou, Cheryl H Arrowsmith, Brian Raught, Miquel Angel Pujana, Karim Mekhail, Anne Hakem, Razqallah Hakem
Feb 15, 2021
Germline mutations in BRCA1 and BRCA2 (BRCA1/2) genes considerably increase breast and ovarian cancer risk. Given that tumors with these mutations have elevated genomic instability, they exhibit relative vulnerability to certain...
Drug therapies for peripheral joint disease in psoriatic arthritis
Maria Laura Acosta Felquer, Laura C Coates, Enrique R Soriano, Roberto Ranza, Luis R Espinoza, Philip S Helliwell, Oliver FitzGerald, Neil McHugh, Euthalia Roussou, Philip J Mease
Nov 01, 2014
In 2009, GRAPPA published their first evidence-based recommendations for the treatment of psoriasis and psoriatic arthritis (PsA). Since then, new information has been published and drugs developed. We summarize evidence for the...
Drug therapies for peripheral joint disease in psoriatic arthritis
Maria Laura Acosta Felquer, Laura C Coates, Enrique R Soriano, Roberto Ranza, Luis R Espinoza, Philip S Helliwell, Oliver FitzGerald, Neil McHugh, Euthalia Roussou, Philip J Mease
Nov 01, 2014
In 2009, GRAPPA published their first evidence-based recommendations for the treatment of psoriasis and psoriatic arthritis (PsA). Since then, new information has been published and drugs developed. We summarize evidence for the...
R/BHC
BACKGROUND: Although the use of clustering methods has rapidly become one of the standard computational approaches in the literature of microarray gene expression data analysis, little attention has been paid to uncertainty in...
Erasmian Didacticism and Political Advice in Luis Zapata’s <i>Carlo famoso</i>
Jessica Hagley
Nov 09, 2020
The presence of Erasmian discourse in Luis Zapata’s Carlo famoso (1566) has been both neglected and misinterpreted in literary scholarship. Previously understood as an expression of insubordination against the reign of Philip...
The Expansion of Approximant /r/ in Dutch
Renée Van Bezooijen
Sep 30, 2014
In present-day Standard Dutch as spoken in the Netherlands, three main categories of pronunciation variants of Irl can be distinguished, namely alveolar /r/, uvular /r/, and approximant /r/. Approximant /r/, the focus of this...
Published by: Atlantic Provinces Linguistic Association
Alphonse R. Dochez, 1925
The Rockefeller University
Jan 01, 0001
Alphonse R. Dochez. Etiology of Scarlet Fever
Lecture delivered January 17th, 1925
Posted with permission
Published by: J.B. Lippincott Company
Florence R. Sabin, 1915
The Rockefeller University
Jan 01, 0001
Prof. Florence R. Sabin. The Method of Growth of the Lymphatic System
Lecture delivered December 18th, 1915
Published by: J.B. Lippincott Company
Personality Antecedents of EWoM in Determining Online Customer Purchase Behavior
Electronic word of mouth (EWoM) is similar to the standard word of mouth- the only difference is, the use of Internet as a base in EWoM. By understanding the personality antecedents of EWoM, the consumer buyer beahviour could be...
Published by: IGI Global Scientific Publishing
The Expansion of Approximant /r/ in Dutch
Renée Van Bezooijen
Sep 30, 2014
In present-day Standard Dutch as spoken in the Netherlands, three main categories of pronunciation variants of Irl can be distinguished, namely alveolar /r/, uvular /r/, and approximant /r/. Approximant /r/, the focus of this...
Published by: Atlantic Provinces Linguistic Association
Bayesian Spatial Modelling with R-INLA
The principles behind the interface to continuous domain spatial models in the R- INLA software package for R are described. The integrated nested Laplace approximation (INLA) approach proposed by Rue, Martino, and Chopin (2009)...
Bayesian Spatial Modelling with R-INLA
The principles behind the interface to continuous domain spatial models in the R- INLA software package for R are described. The integrated nested Laplace approximation (INLA) approach proposed by Rue, Martino, and Chopin (2009)...
Using R and Bioconductor for proteomics data analysis.
This review presents how R, the popular statistical environment and programming language, can be used in the frame of proteomics data analysis. A short introduction to R is given, with special emphasis on some of the features...
Bore collapse and wave run-up on a sandy beach
Wave run-up on beaches and coastal structures is initiated and driven by collapsing incident bores, this process is often considered to define the seaward limit of the swash zone. It is hence a key feature in nearshore wave...
A farewell to <i>R</i>
The time-dependent reproduction number, Rt, is a key metric used by epidemiologists to assess the current state of an outbreak of an infectious disease. This quantity is usually estimated using...
Orchestrating privacy-protected big data analyses of data from different resources with R and DataSHIELD.
Yannick Marcon, Tom Bishop, Demetris Avraam, Xavier Escriba-Montagut, Patricia Ryser-Welch, Stuart Wheater, Paul Burton, Juan R González
Apr 09, 2021
Combined analysis of multiple, large datasets is a common objective in the health- and biosciences. Existing methods tend to require researchers to physically bring data together in one place or follow an analysis plan and share...
Explanatory Adequacy in Phonology
Eric Russell Webb
Aug 01, 2013
This work reexamines phonological variation particular to the /R/ of convergent French, departing from the hypothesis that a deductive approach to this question can offer explanatory advantages. In contrast to data-driven...
Published by: Atlantic Provinces Linguistic Association
Bore collapse and wave run-up on a sandy beach
Wave run-up on beaches and coastal structures is initiated and driven by collapsing incident bores, this process is often considered to define the seaward limit of the swash zone. It is hence a key feature in nearshore wave...
Dysfunctional brain dynamics and their origin in Lewy body dementia.
Julia Schumacher, Luis R Peraza, Michael Firbank, Alan J Thomas, Marcus Kaiser, Peter Gallagher, John T O'Brien, Andrew M Blamire, John-Paul Taylor
Jul 16, 2019
Lewy body dementia includes dementia with Lewy bodies and Parkinson's disease dementia and is characterized by transient clinical symptoms such as fluctuating cognition, which might be driven by dysfunction of the intrinsic...
Asymmetric Information and R&D Disclosure
We examine how asymmetric information in financial markets affects voluntary research and development (R&D) disclosure, considering scientific publications as a disclosure channel. Difference-in-differences regressions...
Asymmetric Information and R&D Disclosure
We examine how asymmetric information in financial markets affects voluntary research and development (R&D) disclosure, considering scientific publications as a disclosure channel. Difference-in-differences regressions...
The CBI-R detects early behavioural impairment in genetic frontotemporal dementia.
Annabel Nelson, Lucy L Russell, Georgia Peakman, Rhian S Convery, Arabella Bouzigues, Caroline V Greaves, Martina Bocchetta, David M Cash, John C van Swieten, Lize Jiskoot, Fermin Moreno, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Barbara Borroni, Elizabeth Finger, Matthis Synofzik, Daniela Galimberti, Rik Vandenberghe, Alexandre de Mendonça, Chris R Butler, Alexander Gerhard, Simon Ducharme, Isabelle Le Ber, Isabel Santana, Florence Pasquier, Johannes Levin, Markus Otto, Sandro Sorbi, Jonathan D Rohrer, Genetic FTD Initiative (GENFI)
Sep 10, 2022
INTRODUCTION: Behavioural dysfunction is a key feature of genetic frontotemporal dementia (FTD) but validated clinical scales measuring behaviour are lacking at present. METHODS: We assessed behaviour using the revised version...
Characterization of steel billet scales generated during the continuous casting process in SIDERPERU steel plant
Abstract Tons of waste is produced during iron steel’s industrial production, creating environmental pollution. This work aims to characterize the steel scale formed on the billet surface during...
LE Borja-Castro, A Bustamante Dominguez, MI Valerio-Cuadros, RA Valencia-Bedregal, HA Cabrera-Tinoco, SM Espinoza Suarez, J Kargin, NO Moreno, Crispin Barnes, Luis De Los Santos Valladares
Dec 24, 2021
rpsftm
Treatment switching in a randomised controlled trial occurs when participants change from their randomised treatment to the other trial treatment during the study. Failure to account for treatment switching in the analysis (i.e....
A quantitative analysis 0f word-final /r/-deletion in Brazilian Portugese
Walcir Cardoso
Jul 18, 2013
This study provides a quantitative analysis for the process of word-final /r/-deletion in the dialect of Portuguese spoken in the city of Belem, in northern Brazil. Two linguistic and four extralinguistic factors are considered...
Published by: Atlantic Provinces Linguistic Association
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