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Is IL-6 Back in trans Signaling for Inflammatory Bowel Disease?
Delivering early, robust hints of potential efficacy is one of the most daunting challenges in drug development. No matter how good the theoretical and preclinical rationale, in the end it is only a large-scale ‘experiment in...
Evolution of social monogamy in primates is not consistently associated with male infanticide.
This is the accepted manuscript version of the article. The final published version is available from PNAS Online at http://www.pnas.org/content/111/17/E1674.extract.
A purine metabolic checkpoint that prevents autoimmunity and autoinflammation.
Svetlana Saveljeva, Gavin W Sewell, Katharina Ramshorn, M Zaeem Cader, James A West, Simon Clare, Lea-Maxie Haag, Rodrigo Pereira de Almeida Rodrigues, Lukas W Unger, Ana Belén Iglesias-Romero, Lorraine M Holland, Christophe Bourges, Muhammad N Md-Ibrahim, James O Jones, Richard S Blumberg, James C Lee, Nicole C Kaneider, Trevor D Lawley, Allan Bradley, Gordon Dougan, Arthur Kaser
Feb 05, 2022
Still's disease, the paradigm of autoinflammation-cum-autoimmunity, predisposes for a cytokine storm with excessive T lymphocyte activation upon viral infection. Loss of function of the purine nucleoside enzyme FAMIN is the sole...
Cerebrovascular Response to Phenylephrine in Traumatic Brain Injury
Intravenous phenylephrine (PE) is utilized commonly in critical care for cardiovascular support. Its impact on the cerebrovasculature is unclear and its use may have important implications during states of critical neurological...
The Grizzly, October 3, 1986
Joseph F. Pirro, Craig DiLouie, Lora L. Hart, Angela M. Salas, Bill Connolly, Jill Theurer, Lynne Edwards, Maria D'Arcangelo, Richard P. Richter
Jan 01, 0001
Berman Collection Former Phila. Cop Anchors Security Force Letters: Not Ones to Dampen Festive Spirits; What is this thing?; It's Aluminating! Not a Dichotomous Community Temple Fires Conversation Perhaps More Than Unger...
Ursinus College Collegeville Pennsylvania newspaper resume writing Soccer Football field hockey Joanne Schoenherr resident assistants Debbie Nolan campus sculptures Brian McCullough Fetterolf House Philip Berman Muriel Berman cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The impact of hypertonic saline on cerebrovascular reactivity and compensatory reserve in traumatic brain injury
Logan Froese, Joshua Dian, Carleen Batson, Alwyn Gomez, Bertram Unger, Frederick A Zeiler
Oct 23, 2020
BACKGROUND: Intravenous hypertonic saline is utilized commonly in critical care for treatment of acute or refractory elevations of intracranial pressure (ICP) in traumatic brain injury (TBI) patients. Though there is a clear...
Cerebrovascular Circulation cerebrovascular response Hypertonic saline Intracranial Pressure pressure reactivity index Sodium Chloride Adult Arterial Pressure Brain Injuries Traumatic Cerebrovascular Circulation Female Hemodynamics Humans Intracranial Hypertension Intracranial Pressure Male Middle Aged Retrospective Studies Saline Solution Hypertonic Young Adult
Allograft rejection is associated with development of functional IgE specific for donor MHC antigens.
Andreas M Farkas, Ulrike Baranyi, Georg A Böhmig, Lukas Unger, Stefan Hopf, Markus Wahrmann, Heinz Regele, Benedikt Mahr, Christoph Schwarz, Karin Hock, Nina Pilat, Ivan Kristo, Jasmin Mraz, Christian Lupinek, Josef Thalhamer, Gregor Bond, Lorenz Kuessel, Elizabeth Wlodek, Jack Martin, Menna Clatworthy, Gavin Pettigrew, Rudolf Valenta, Thomas Wekerle
Dec 17, 2018
BACKGROUND: Donor-specific antibodies of the IgG isotype are measured routinely for diagnostic purposes in renal transplant recipients and are associated with antibody-mediated rejection and long-term graft loss. OBJECTIVE: This...
IgE Transplantation alloreactivity donor-specific antibodies humoral rejection immunology Allografts Animals Female Graft Rejection Heart Transplantation Histocompatibility Antigens Class I Histocompatibility Antigens Class II Humans Immunoglobulin E Immunoglobulin G Kidney Transplantation Male Mice Mice Inbred BALB C Skin Transplantation
Computer Vision for Continuous Bedside Pharmacological Data Extraction
Logan Froese, Joshua Dian, Carleen Batson, Alwyn Gomez, Amanjyot Singh Sainbhi, Bertram Unger, Frederick A Zeiler
Sep 10, 2021
Introduction: As real time data processing is integrated with medical care for traumatic brain injury (TBI) patients, there is a requirement for devices to have digital output. However, there are still many devices that fail to...
Practical Implications On How Established Companies Innovate With Startups
The study addresses an important literature gap concerning open innovation and startups. The purpose of this article is to deliver tools and guidelines for innovation managers to support their decision-making when aspiring to...
Published by: IGI Global Scientific Publishing
Accuracy of Optic Nerve Sheath Diameter Measurements in Pocket-Sized Ultrasound Devices in a Simulation Model.
Garrett GRJ Johnson, Tomislav Jelic, Angela Derksen, Bertram Unger, Frederick A Zeiler, Markus T Ziesmann, Lawrence M Gillman
Apr 20, 2022
INTRODUCTION: Transorbital sonographic measurement of optic nerve sheath diameter (ONSD) is an emerging non-invasive technique for the identification and monitoring of intracranial hypertension. In recent years, new pocket...
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