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Results: 689
Native point defects of semiconducting layered Bi2O2Se.
Bi2O2Se is an emerging semiconducting, air-stable layered material (Nat. Nanotechnol. 2017, 12, 530; Nano Lett. 2017, 17, 3021), potentially exceeding MoS2 and phosphorene in electron mobility and rivalling typical Van der Waals...
Damage resistance and damage tolerance of hybrid carbon-glass laminates
The influence of impact energy and stacking sequence on the damage resistance and Compression After Impact (CAI) strength of Carbon and Glass Fibre Reinforced Plastic (CFRP and GFRP respectively) hybrid laminates is...
Fuzzy SVM With Mahalanobis Distance for Situational Awareness-Based Recognition of Public Health Emergencies
In public health emergencies, situational awareness is crucial for swift responses by governments and rescue organizations. In this manuscript, a novel framework is proposed to identify and classify event-specific information...
Published by: IGI Global Scientific Publishing
Damage resistance and damage tolerance of hybrid carbon-glass laminates
The influence of impact energy and stacking sequence on the damage resistance and Compression After Impact (CAI) strength of Carbon and Glass Fibre Reinforced Plastic (CFRP and GFRP respectively) hybrid laminates is...
Photorealistic Audio-driven Video Portraits
Video portraits are common in a variety of applications, such as videoconferencing, news broadcasting, and virtual education and training. We present a novel method to synthesize photorealistic video portraits for an input...
Optimized pharmacological control over the AAV-Gene-Switch vector for regulable gene therapy.
Shi Cheng, Marcel M van Gaalen, Mathias Bähr, Enrique Garea-Rodriguez, Sebastian Kügler
Oct 26, 2021
Gene therapy in its current design is an irreversible process. It cannot be stopped in case of unwanted side effects, nor can expression levels of therapeutics be adjusted to individual patient's needs. Thus, the Gene-Switch...
Confining Nanopore Bipolar Electrochemical Processes to Give Pattern in Space and Time
Frank Marken
Sep 01, 2017
"Wireless" metal-coated nanopore electrode processes have been developed by Long and co-workers (R. Gao, Y. Lin, Y.-L. Ying, X.-Y. Liu, X. Shi, Y.-X. Hu, Y.-T. Long, Small, 2017 DOI: 10.1002/smll.201700234), confining bipolar...
Confining Nanopore Bipolar Electrochemical Processes to Give Pattern in Space and Time
Frank Marken
Sep 01, 2017
"Wireless" metal-coated nanopore electrode processes have been developed by Long and co-workers (R. Gao, Y. Lin, Y.-L. Ying, X.-Y. Liu, X. Shi, Y.-X. Hu, Y.-T. Long, Small, 2017 DOI: 10.1002/smll.201700234), confining bipolar...
Photorealistic Audio-driven Video Portraits
Video portraits are common in a variety of applications, such as videoconferencing, news broadcasting, and virtual education and training. We present a novel method to synthesize photorealistic video portraits for an input...
One-step preparation of microporous Pd@cPIM composite catalyst film for triphasic electrocatalysis
Shi Xuan Leong, Mariolino Carta, Richard Malpass-Evans, Neil B. Mckeown, Elena Madrid, Frank Marken
Jan 01, 2018
Triphasic microporous materials (containing solid, liquid, and gas) are of interest in electrocatalysis. In this exploratory study, a polymer of intrinsic microporosity (PIM-EA-TB) is impregnated with PdCl4 2...
Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes.
Shi-Xiong Tan, Yvonne Ng, Christopher C Meoli, Ansu Kumar, Poh-Sim Khoo, Daniel J Fazakerley, Jagath R Junutula, Shireen Vali, David E James, Jacqueline Stöckli
Aug 28, 2020
Akt plays a major role in insulin regulation of metabolism in muscle, fat, and liver. Here, we show that in 3T3-L1 adipocytes, Akt operates optimally over a limited dynamic range. This indicates that Akt is a highly sensitive...
3T3-L1 Cells Adipocytes Animals Antibiotics Antineoplastic Computer Simulation Energy Metabolism Glucose Transporter Type 4 Hypoglycemic Agents Insulin Insulin Receptor Substrate Proteins Insulin Resistance Mice Nonlinear dynamics Phosphorylation Platelet-Derived Growth Factor Proto-Oncogene Proteins c-akt RNA Small Interfering Signal Transduction Sirolimus TOR Serine-Threonine Kinases
Adaptive Optimization Algorithm for Resetting Techniques in Obstacle-ridden Environments
Redirected Walking (RDW) algorithms aim to impose several types of gains on users immersed in Virtual Reality and distort their walking paths in the real world, thus enabling them to explore a larger space. Since collision...
Unpacking the process of resource allocation within an entrepreneurial ecosystem
While entrepreneurial ecosystems (EEs) are often regarded as spatially bounded resource allocation systems that allocate and mobilise resources for new venture creation, less is known on the underlying process of resource...
Silver Nanoflakes-Enhanced Anisotropic Hybrid Composites for Integratable Pressure Sensors.
Qingtian Zhang, Guolin Yun, Shida Jin, Zexin Chen, Shi-Yang Tang, Hongda Lu, Haiping Du, Weihua Li
Jan 04, 2023
Flexible pressure sensors based on polymer elastomers filled with conductive fillers show great advantages in their applications in flexible electronic devices. However, integratable high-sensitivity pressure sensors remain...
One-step preparation of microporous Pd@cPIM composite catalyst film for triphasic electrocatalysis
Shi Xuan Leong, Mariolino Carta, Richard Malpass-Evans, Neil B. Mckeown, Elena Madrid, Frank Marken
Jan 01, 2018
Triphasic microporous materials (containing solid, liquid, and gas) are of interest in electrocatalysis. In this exploratory study, a polymer of intrinsic microporosity (PIM-EA-TB) is impregnated with PdCl4 2...
Adaptive Optimization Algorithm for Resetting Techniques in Obstacle-ridden Environments
Redirected Walking (RDW) algorithms aim to impose several types of gains on users immersed in Virtual Reality and distort their walking paths in the real world, thus enabling them to explore a larger space. Since collision...
Highly Efficient Light-Emitting Diodes of Colloidal Metal-Halide Perovskite Nanocrystals beyond Quantum Size.
Young-Hoon Kim, Christoph Wolf, Young-Tae Kim, Himchan Cho, Woosung Kwon, Sungan Do, Aditya Sadhanala, Chan Gyung Park, Shi-Woo Rhee, Sang Hyuk Im, Richard H Friend, Tae-Woo Lee
Nov 24, 2017
Colloidal metal-halide perovskite quantum dots (QDs) with a dimension less than the exciton Bohr diameter DB (quantum size regime) emerged as promising light emitters due to their spectrally narrow light, facile color tuning...
Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury.
Hiran A Prag, Dunja Aksentijevic, Andreas Dannhorn, Abigail V Giles, John F Mulvey, Olga Sauchanka, Luping Du, Georgina Bates, Johannes Reinhold, Duvaraka Kula-Alwar, Zhelong Xu, Luc Pellerin, Richard JA Goodwin, Michael P Murphy, Thomas Krieg
Sep 12, 2022
BACKGROUND: Inhibiting SDH (succinate dehydrogenase), with the competitive inhibitor malonate, has shown promise in ameliorating ischemia/reperfusion injury. However, key for translation to the clinic is understanding the...
Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage.
Li Jianwei, Chacko Jobichen, Satoru Machida, Sun Meng, Randy J Read, Chen Hongying, Shi Jian, Yuren Adam Yuan, J Sivaraman
Apr 14, 2023
Cas12a is a programmable nuclease for adaptive immunity against invading nucleic acids in CRISPR-Cas systems. Here, we report the crystal structures of apo Cas12a from Lachnospiraceae bacterium MA2020 (Lb2) and the...
Published by: PLoS biology
Stable cellulose nanofibril microcapsules from Pickering emulsion templates
Hui Shi Huishi, Kazi M.Zakir Hossain, Davide Califano, Ekanem Ekanem, Ciaran Callaghan, Janet L Scott, Davide Mattia, Karen Edler
Mar 22, 2022
Electrostatic attractions are essential in any complex formation between the nanofibrils of the opposite charge for a specific application, such as microcapsule production. Here, we used cationized cellulose nanofibril...
Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo.
Hiran Prag, Laura Pala, Duvaraka Kula-Alwar, John F Mulvey, Du Luping, Timothy E Beach, Lee M Booty, Andrew R Hall, Angela Logan, Volha Sauchanka, Stuart T Caldwell, Ellen L Robb, Andrew James, Zhelong Xu, Kourosh Saeb-Parsy, Richard C Hartley, Mike Murphy, Thomas Krieg
Jul 30, 2020
PURPOSE: Mitochondrial reactive oxygen species (ROS) production upon reperfusion of ischemic tissue initiates the ischemia/reperfusion (I/R) injury associated with heart attack. During ischemia, succinate accumulates and its...
Structure Analysis of General Type-2 Fuzzy Controller and Its Application
Jianzhong Shi
Jan 01, 2023
In this paper, a general type-2 fuzzy controller is proposed. The proposed general type-2 fuzzy controller is based on α-plane representation, which converts the centroid of general type-2 fuzzy sets to centroids of several...
Published by: IGI Global Scientific Publishing
Ester Prodrugs of Malonate with Enhanced Intracellular Delivery Protect Against Cardiac Ischemia-Reperfusion Injury In Vivo.
Hiran A Prag, Laura Pala, Duvaraka Kula-Alwar, John F Mulvey, Du Luping, Timothy E Beach, Lee M Booty, Andrew R Hall, Angela Logan, Volha Sauchanka, Stuart T Caldwell, Ellen L Robb, Andrew M James, Zhelong Xu, Kourosh Saeb-Parsy, Richard C Hartley, Michael P Murphy, Thomas Krieg
Jan 28, 2022
PURPOSE: Mitochondrial reactive oxygen species (ROS) production upon reperfusion of ischemic tissue initiates the ischemia/reperfusion (I/R) injury associated with heart attack. During ischemia, succinate accumulates and its...
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