Search

Aminoquinolines Animals Antineoplastic Agents BRCA1 Protein BRCA2 Protein Biomarkers Tumor Cell Proliferation DNA Breaks Double-Stranded Dose-Response Relationship Drug Drug Resistance Neoplasm G-Quadruplexes G2 Phase Cell Cycle Checkpoints HEK293 Cells Humans Intracellular Signaling Peptides and Proteins Mad2 Proteins Male Mice Nude Molecular Targeted Therapy Neoplasms Picolinic Acids Poly(ADP-ribose) Polymerase Inhibitors RNA Interference Telomere Time Factors Transfection Tumor Burden Tumor Suppressor p53-Binding Protein 1 Xenograft Model Antitumor Assays

The telomeric repeat-binding factor 2 (TRF2) is a telomere-capping protein that plays a key role in the maintenance of telomere structure and function. It is highly expressed in different cancer types, and it contributes to...

TRF2 miR-182-3p target therapy telomeres Triple-negative breast cancer Animals Humans Mice Apoptosis Cell Line Tumor Gene Expression Regulation Neoplastic MicroRNAs Telomere Triple Negative Breast Neoplasms

BRCA1 BRCA2 DNA damage responses alkylating agents cisplatin Animals BRCA1 Protein BRCA2 Protein Cell Line Tumor Chlorambucil Cricetinae Drug Delivery Systems Drug Resistance Neoplasm Humans Leukemia Lymphocytic Chronic B-Cell Male Mice Mice SCID Peroxisome Proliferator-Activated Receptors Phthalazines Piperazines Xenograft Model Antitumor Assays