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The Origin of Inequality. Origini 3, edited by Andrea Cardarelli, Alberto Cazzella and Marcella Frangipane
The article reviews The Origins of Inequality, a collection of essays brought together by Andrea Cardarelli, Alberto Cazzella and Marcella Frangipane following a series of seminars on this theme at the University of Roma La...
Typhoid conjugate vaccines
Jason R Andrews, Stephen Baker, Florian Marks, Marcella Alsan, Denise Garrett, Bruce G Gellin, Samir K Saha, Farah Naz Qamar, Mohammad Tahir Yousafzai, Isaac I Bogoch, Marina Antillon, Virginia E Pitzer, Jong-Hoon Kim, Jacob John, Jillian Gauld, Vittal Mogasale, Edward T Ryan, Stephen P Luby, Nathan C Lo
Aug 01, 2019
Typhoid fever is an acute systemic infectious disease responsible for an estimated 12-20 million illnesses and over 150 000 deaths annually. In March, 2018, a new recommendation was issued by WHO for the programmatic use of...
Pearl of Africa: Condemnation and Celebration in Uganda
Marcella AM McGill
Jan 01, 0001
This research examines the intentions and consequences of the British colonial endeavor in the country of Uganda, East Africa. Focusing on issues of gender, education, and language, it provides a survey of the multifaceted...
Uganda Education gender roles language linguistic Colonialism development missionaries african history African Languages and Societies History
Published by: Ursinus College
Pearl of Africa: British Colonialism's Role in Ugandan Education and Modern Repercussions for Nonprofits
Marcella McGill
Jan 01, 0001
This research examines how the British formed and influenced educational institutions in Uganda during the colonial era. It then looks at how these traits carry over into the modern era and some of the issues associated with...
Uganda Education Gender foreign language medium of instruction East Africa Suubi Project african history African Languages and Societies African Studies Arts and Humanities Bilingual, Multilingual, and Multicultural Education Educational Methods Feminist, Gender, and Sexuality Studies History Missions and World Christianity Nonprofit Administration and Management Women's Studies
Published by: Ursinus College
Introduction
Marcella Pellegrino Sutcliffe
Aug 03, 2015
This is the author accepted manuscript. The final version is available from Taylor & Francis via http://dx.doi.org/10.1080/0046760X.2015.1063712
Domain decomposition preconditioning for the high-frequency time-harmonic Maxwell equations with absorption
This paper rigorously analyses preconditioners for the timeharmonic Maxwell equations with absorption, where the PDE is discretised using curl-conforming finite-element methods of fixed, arbitrary order and the preconditioner...
Absorption Domain decomposition GMRES high frequency Iterative solvers Maxwell equations Preconditioning /dk/atira/pure/subjectarea/asjc/2600/2602 name=Algebra and Number Theory /dk/atira/pure/subjectarea/asjc/2600/2605 name=Computational Mathematics /dk/atira/pure/subjectarea/asjc/2600/2604 name=Applied Mathematics
Domain decomposition preconditioning for the high-frequency time-harmonic Maxwell equations with absorption
This paper rigorously analyses preconditioners for the timeharmonic Maxwell equations with absorption, where the PDE is discretised using curl-conforming finite-element methods of fixed, arbitrary order and the preconditioner...
Absorption Domain decomposition GMRES high frequency Iterative solvers Maxwell equations Preconditioning /dk/atira/pure/subjectarea/asjc/2600/2602 name=Algebra and Number Theory /dk/atira/pure/subjectarea/asjc/2600/2605 name=Computational Mathematics /dk/atira/pure/subjectarea/asjc/2600/2604 name=Applied Mathematics
Fat mass and obesity-related (FTO) shuttles between the nucleus and cytoplasm.
Pawan Gulati, Edward Avezov, Marcella Ma, Robin Antrobus, Paul Lehner, Stephen O'Rahilly, Giles SH Yeo
Sep 29, 2014
3D-Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices.
Janko Kajtez, Sebastian Buchmann, Shashank Vasudevan, Marcella Birtele, Stefano Rocchetti, Christian Jonathan Pless, Arto Heiskanen, Roger A Barker, Alberto Martínez-Serrano, Malin Parmar, Johan Ulrik Lind, Jenny Emnéus
Jul 16, 2020
Compartmentalized microfluidic platforms are an invaluable tool in neuroscience research. However, harnessing the full potential of this technology remains hindered by the lack of a simple fabrication approach for the creation...
Electrochemical Characterisation of Bio-Bottle-Voltaic (BBV) Systems Operated with Algae and Built with Recycled Materials.
Peter Bateson, Jack EH Fleet, Anthony S Riseley, Elena Janeva, Anastasia S Marcella, Chiara Farinea, Maria Kuptsova, Núria Conde Pueyo, Christopher J Howe, Paolo Bombelli, Brenda M Parker
Sep 10, 2018
Photobioelectrochemical systems are an emerging possibility for renewable energy. By exploiting photosynthesis, they transform the energy of light into electricity. This study evaluates a simple, scalable bioelectrochemical...
A Segue From Search to Dialogue
Jon Mason, Marcella Dillig, Anselm Böhmer, Stephen Bolaji, Illie Isso, Mirona Stănescu, Hilal Sahin, Aslihan Kuraner
Feb 07, 2024
For over two decades, educational technologies have been embedded within an approach to inquiry dominated by the “search paradigm.” However, conversational AI presents an opportunity to shift this paradigm towards enhancing...
Artificial Intelligence Education Educational Technologies Computer Science and Information Technology Security and Forensics
Published by: IGI Global Scientific Publishing
Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome.
Joseph Polex-Wolf, Brian YH Lam, Rachel Larder, John Tadross, Debra Rimmington, Fàtima Bosch, Verónica Jiménez Cenzano, Eduard Ayuso, Marcella Kl Ma, Kara Rainbow, Anthony P Coll, Stephen O'Rahilly, Giles SH Yeo
Mar 20, 2018
Profound hyperphagia is a major disabling feature of Prader-Willi syndrome (PWS). Characterization of the mechanisms that underlie PWS-associated hyperphagia has been slowed by the paucity of animal models with increased food...
Thyroid Deficiency Before Birth Alters the Adipose Transcriptome to Promote Overgrowth of White Adipose Tissue and Impair Thermogenic Capacity.
Shelley E Harris, Miles J De Blasio, Xiaohui Zhao, Marcella Ma, Katie Davies, FB Peter Wooding, Russell S Hamilton, Dominique Blache, David Meredith, Andrew J Murray, Abigail L Fowden, Alison J Forhead
Feb 19, 2020
Phenotypic characterization of Adig null mice suggests roles for adipogenin in the regulation of fat mass accrual and leptin secretion.
Anna Alvarez-Guaita, Satish Patel, Koini Lim, Afreen Haider, Liang Dong, Olivia J Conway, Marcella Kl Ma, Davide Chiarugi, Vladimir Saudek, Stephen O'Rahilly, David B Savage
Feb 11, 2021
Adipogenin (Adig) is an adipocyte-enriched transmembrane protein. Its expression is induced during adipogenesis in rodent cells, and a recent genome-wide association study associated body mass index (BMI)-adjusted leptin levels...
Combination of Ginsenosides Rb2 and Rg3 Promotes Angiogenic Phenotype of Human Endothelial Cells via PI3K/Akt and MAPK/ERK Pathways.
Ran Joo Choi, Siti Zuraidah Mohamad Zobir, Ben Alexander-Dann, Nitin Sharma, Marcella Kl Ma, Brian YH Lam, Giles SH Yeo, Weidong Zhang, Tai-Ping Fan, Andreas Bender
Feb 24, 2021
Shexiang Baoxin Pill (SBP) is an oral formulation of Chinese materia medica for the treatment of angina pectoris. It displays pleiotropic roles in protecting the cardiovascular system. However, the mode of action of SBP in...
Octopaminergic neurons have multiple targets in Drosophila larval mushroom body calyx and can modulate behavioral odor discrimination.
JY Hilary Wong, Bo Angela Wan, Tom Bland, Marcella Montagnese, Alex D McLachlan, Cahir J O'Kane, Shuo Wei Zhang, Liria M Masuda-Nakagawa
Nov 09, 2020
Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells.
Ming Yang, Tamana Darwish, Pierre Larraufie, Debra Rimmington, Irene Cimino, Deborah A Goldspink, Benjamin Jenkins, Albert Koulman, Cheryl A Brighton, Marcella Ma, Brian YH Lam, Anthony P Coll, Stephen O'Rahilly, Frank Reimann, Fiona M Gribble
Jan 06, 2021
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain.
Marcella Birtele, Petter Storm, Yogita Sharma, Janko Kajtez, Jenny Nelander Wahlestedt, Edoardo Sozzi, Fredrik Nilsson, Simon Stott, Xiaoling L He, Bengt Mattsson, Daniella Rylander Ottosson, Roger A Barker, Alessandro Fiorenzano, Malin Parmar
Dec 12, 2022
Proopiomelanocortin Processing in the Hypothalamus Is Directly Regulated by Saturated Fat
Daniela S Razolli, Thiago M de Araújo, Marcella R Sant Apos Ana, Peter Kirwan, Dennys E Cintra, Florian T Merkle, Licio A Velloso
Jun 28, 2019
In outbred mice, susceptibility or resistance to diet-induced obesity is associated with rapid changes in hypothalamic proopiomelanocortin (POMC) levels. Here, we evaluated 3 hypotheses that potentially explain the development...
Behavioural and neurochemical mechanisms underpinning the feeding-suppressive effect of GLP-1/CCK combinatorial therapy
Clemence Blouet, Emma Roth, Simon Benoit, Baptiste Quentin, Brian Lam, Sarah Will, Marcella Ma, Nick Heeley, Tamana Darwish, Yashaswi Shrestha, Fiona Gribble, Frank Reimann, Irina Pshenichnaya, Giles Yeo, David Baker, James Trevaskis
Nov 16, 2020
Combinatorial therapies are under intense investigation for the development of more efficient anti-obesity drugs, however little is known about how they act in brain to produce enhanced anorexia and weight loss. Objectives: The...
CCK Combinatorial therapy GLP-1 Hunger Nucleus of the solitary tract obesity satiety Animals Anti-Obesity Agents Appetite Regulation Brain Diet High-Fat Eating Feeding Behavior Glucagon-Like Peptide 1 Glucagon-Like Peptide-1 Receptor Male Mice Mice Inbred C57BL Neurons obesity Receptors Cholecystokinin Solitary Nucleus Weight Loss
FTO is necessary for the induction of leptin resistance by high-fat feeding.
YC Loraine Tung, Pawan Gulati, Che-Hsiung Liu, Debra Rimmington, Rowena Dennis, Marcella Ma, Vladimir Saudek, Stephen O'Rahilly, Anthony P Coll, Giles SH Yeo
Apr 22, 2015
FTO FaT mass and Obesity related Fto GWAS Genome-wide association studies HFD high-fat diet High-fat diet Hypothalamus ICV intracerebroventricular injection Irx3 Iroquois Homeobox 3 Leptin resistance MEF Mouse embryonic fibroblasts NFкB Ob-R leptin receptor PTPs protein-tyrosine phosphatase SNPs single nucleotide polymorphisms SOCS3 SOCS3 suppressor of cytokine signalling TRIP4 Tlr4 Toll-like receptor 4 WAT white adipose tissue Y2H Yeast two-hybrid
Contributions of Function-Altering Variants in Genes Implicated in Pubertal Timing and Body Mass for Self-Limited Delayed Puberty.
Sasha R Howard, Leonardo Guasti, Ariel Poliandri, Alessia David, Claudia P Cabrera, Michael R Barnes, Karoliina Wehkalampi, Stephen O'Rahilly, Catherine E Aiken, Anthony P Coll, Marcella Ma, Debra Rimmington, Giles SH Yeo, Leo Dunkel
Feb 05, 2018
CONTEXT: Self-limited delayed puberty (DP) is often associated with a delay in physical maturation, but although highly heritable the causal genetic factors remain elusive. Genome-wide association studies of the timing of...
Inhibition of mitochondrial function by metformin increases glucose uptake, glycolysis and GDF-15 release from intestinal cells
On a New Theoretical Framework for RR Lyrae Stars. II. Mid-infrared Period-Luminosity-Metallicity Relations
Jillian R. Neeley, Massimo Marengo, Giuseppe Bono, Vittorio F. Braga, Massimo Dall'ora, Davide Magurno, Marcella Marconi, Nicolas Trueba, Emanuele Tognelli, Pier G.Prada Moroni, Rachael L. Beaton, Wendy L. Freedman, Barry F. Madore, Andrew J. Monson, Victoria Scowcroft, Mark Seibert, Peter B. Stetson
Jun 01, 2017
We present new theoretical period-luminosity-metallicity (PLZ) relations for RR Lyræ stars (RRLs) at Spitzer and WISE wavelengths. The PLZ relations were derived using nonlinear, time-dependent convective hydrodynamical...
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