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Minimum cost network design in strategic alliances
Strategic alliances are established between firms to improve their competitiveness in markets and generally appear in the form of joint ventures. Such collaborative efforts require centralized planning, and the survival of...
Centralized planning collaboration Network design Strategic alliances transaction costs /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management /dk/atira/pure/subjectarea/asjc/1800/1803 name=Management Science and Operations Research /dk/atira/pure/subjectarea/asjc/1800/1802 name=Information Systems and Management
Minimum cost network design in strategic alliances
Strategic alliances are established between firms to improve their competitiveness in markets and generally appear in the form of joint ventures. Such collaborative efforts require centralized planning, and the survival of...
Centralized planning collaboration Network design Strategic alliances transaction costs /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management /dk/atira/pure/subjectarea/asjc/1800/1803 name=Management Science and Operations Research /dk/atira/pure/subjectarea/asjc/1800/1802 name=Information Systems and Management
Winthrop Dance Theatre 2015 Features Bodiography Creator Maria Caruso
Winthrop University
Jan 01, 0001
Maria Caruso created Bodiography to celebrate dancers of all shapes and sizes. When choreographer Maria Caruso created her company Bodiography, she set out to celebrate dancers of all shapes and sizes. She has since won acclaim...
Published by: Winthrop University
Progressive tauopathy in P301S tau transgenic mice is associated with a functional deficit of the olfactory system.
Tau aggregation and its relation to selected forms of neuronal cell death.
How neurons die in neurodegenerative diseases is still unknown. The distinction between apoptosis as a genetically controlled mechanism, and necrosis, which was viewed as an unregulated process, has blurred with the...
Propagation of Tau aggregates.
Since 2009, evidence has accumulated to suggest that Tau aggregates form first in a small number of brain cells, from where they propagate to other regions, resulting in neurodegeneration and disease. Propagation of Tau...
MSI and EBV Positive Gastric Cancer's Subgroups and Their Link With Novel Immunotherapy
Maria Grazia Rodriquenz, Giandomenico Roviello, Alberto D'Angelo, Daniele Lavacchi, Franco Roviello, Karol Polom
May 11, 2020
Gastric cancers have been historically classified based on histomorphologic features. The Cancer Genome Atlas network reported the comprehensive identification of genetic alterations associated with gastric cancer...
Living in Promiscuity
Alpha-synuclein (α-syn) is a small protein that, in neurons, localizes predominantly to presynaptic terminals. Due to elevated conformational plasticity, which can be affected by environmental factors, in addition to undergoing...
MSI and EBV Positive Gastric Cancer's Subgroups and Their Link With Novel Immunotherapy
Maria Grazia Rodriquenz, Giandomenico Roviello, Alberto D'Angelo, Daniele Lavacchi, Franco Roviello, Karol Polom
May 11, 2020
Gastric cancers have been historically classified based on histomorphologic features. The Cancer Genome Atlas network reported the comprehensive identification of genetic alterations associated with gastric cancer...
Behavioural deficits in transgenic mice expressing human truncated (1-120 amino acid) alpha-synuclein.
ALPHA-SYNUCLEIN dementia with Lewy bodies Memory neurodegeneration Transgenic mouse Age Factors Animals Calcium-Calmodulin-Dependent Protein Kinase Type 2 Disease Models Animal Exploratory Behavior Gene Expression Regulation Humans Lewy Body Disease Male Maze Learning Mice Mice Inbred C57BL Mice Transgenic Peptide Fragments Prosencephalon RNA Messenger ALPHA-SYNUCLEIN
Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders.
Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D'Avino, Maria Grazia Giansanti
Nov 25, 2021
Golgi phosphoprotein 3 (GOLPH3) is a highly conserved peripheral membrane protein localized to the Golgi apparatus and the cytosol. GOLPH3 binding to Golgi membranes depends on phosphatidylinositol 4-phosphate [PI(4)P] and...
Drosophila FMRP GOLPH3 Golgi Cell Cycle male meiosis Spermatogenesis Animals Carcinogenesis Cell Proliferation Cytokinesis Cytoskeleton Drosophila Drosophila Proteins Golgi Apparatus Membrane Proteins Nervous System Nervous System Diseases Oncogene Proteins Phosphatidylinositol Phosphates Protein Interaction Maps Protein Transport
Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia.
Jack Brelstaff, Aviva M Tolkovsky, Bernardino Ghetti, Michel Goedert, Maria Grazia Spillantini
Oct 03, 2018
Tau protein forms insoluble filamentous inclusions that are closely associated with nerve cell death in many neurodegenerative diseases. How neurons die in these tauopathies is unclear. We report that living neurons with tau...
Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells.
Jason C Sang, Eric Hidari, Georg Meisl, Rohan T Ranasinghe, Maria Grazia Spillantini, David Klenerman
Jun 22, 2021
Aggregation of α-synuclein (α-syn) is closely linked to Parkinson's disease (PD) and the related synucleinopathies. Aggregates spread through the brain during the progression of PD, but the mechanism by which this occurs is...
Published by: Communications biology
Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders
Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti
Sep 09, 2021
Golgi phosphoprotein 3 (GOLPH3) is a highly conserved peripheral membrane protein localized to the Golgi apparatus and the cytosol. GOLPH3 binding to Golgi membranes depends on phosphatidylinositol 4-phosphate [PI(4)P] and...
Identification of GOLPH3 Partners in <i>Drosophila</i> Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders.
Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D'Avino, Maria Grazia Giansanti
Oct 29, 2021
Golgi phosphoprotein 3 (GOLPH3) is a highly conserved peripheral membrane protein localized to the Golgi apparatus and the cytosol. GOLPH3 binding to Golgi membranes depends on phosphatidylinositol 4-phosphate [PI(4)P] and...
Published by: Cells
L444P Gba1 mutation increases formation and spread of α-synuclein deposits in mice injected with mouse α-synuclein pre-formed fibrils.
Anna Migdalska-Richards, Michal Wegrzynowicz, Ian F Harrison, Guglielmo Verona, Vittorio Bellotti, Maria Grazia Spillantini, Anthony HV Schapira
Nov 02, 2020
Parkinson disease is the most common neurodegenerative movement disorder, estimated to affect one in twenty-five individuals over the age of 80. Mutations in glucocerebrosidase 1 (GBA1) represent the most common genetic risk...
Maintenance in gastric cancer
Giandomenico Roviello, Maria Grazia Rodriquenz, Giuseppe Aprile, Alberto D'Angelo, Franco Roviello, Stefania Nobili, Enrico Mini, Italo Sarno, Karol Polom
Apr 30, 2021
The interest in maintenance therapy for patients with advanced cancers has been rapidly growing. Maintenance therapy is a useful strategy that may strengthen results of induction therapy thus extending survival and preserving...
Maintenance in gastric cancer
Giandomenico Roviello, Maria Grazia Rodriquenz, Giuseppe Aprile, Alberto D'Angelo, Franco Roviello, Stefania Nobili, Enrico Mini, Italo Sarno, Karol Polom
Apr 30, 2021
The interest in maintenance therapy for patients with advanced cancers has been rapidly growing. Maintenance therapy is a useful strategy that may strengthen results of induction therapy thus extending survival and preserving...
Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1.
Franca Orsini, Elvina Chrysanthou, Thomas Dudler, W Jason Cummings, Minoru Takahashi, Teizo Fujita, Gregory Demopulos, Maria-Grazia De Simoni, Wilhelm Schwaeble
Apr 12, 2019
BACKGROUND: Complement activation via the lectin activation pathway (LP) has been identified as the key mechanism behind post-ischemic tissue inflammation causing ischemia-reperfusion injury (IRI) which can significantly impact...
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