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Results: 66
Anticancer chemotherapy in teenagers and young adults
Adaptation Psychological Adolescent Adult Antineoplastic Agents Cardiovascular Diseases fatigue Fertility Preservation Humans Infertility Interpersonal Relations Long-Term Care Neoplasms Neoplasms Second Primary Neurocognitive Disorders Patient Participation Precision Medicine Prognosis Risk Factors Social Skills Survivors Young Adult
Integrative radiogenomics for virtual biopsy and treatment monitoring in ovarian cancer
Paula Martin-Gonzalez, Mireia Crispin-Ortuzar, Leonardo Rundo, Maria Delgado-Ortet, Marika Reinius, Lucian Beer, Ramona Woitek, Stephan Ursprung, Helen Addley, James D. Brenton, Florian Markowetz, Evis Sala
Aug 17, 2020
Abstract: Background: Ovarian cancer survival rates have not changed in the last 20 years. The majority of cases are High-grade serous ovarian carcinomas (HGSOCs), which are typically diagnosed at an advanced stage with multiple...
Integrative radiogenomics for virtual biopsy and treatment monitoring in ovarian cancer
Paula Martin-Gonzalez, Mireia Crispin-Ortuzar, Leonardo Rundo, Maria Delgado-Ortet, Marika Reinius, Lucian Beer, Ramona Woitek, Stephan Ursprung, Helen Addley, James D. Brenton, Florian Markowetz, Evis Sala
Aug 17, 2021
Abstract: Background: Ovarian cancer survival rates have not changed in the last 20 years. The majority of cases are High-grade serous ovarian carcinomas (HGSOCs), which are typically diagnosed at an advanced stage with multiple...
Lesion-specific 3D-printed moulds for image-guided tissue multi-sampling of ovarian tumours
Maria Delgado-Ortet, Marika Av Reinius, Cathal McCague, Vlad Bura, Ramona Woitek, Leonardo Rundo, Andrew B Gill, Marcel Gehrung, Stephan Ursprung, Helen Bolton, Krishnayan Haldar, Pubudu Pathiraja, James D Brenton, Mireia Crispin-Ortuzar, Mercedes Jimenez-Linan, Lorena Escudero Sanchez, Evis Sala
Feb 27, 2023
Integrative radiogenomics for virtual biopsy and treatment monitoring in ovarian cancer.
Paula Martin-Gonzalez, Mireia Crispin-Ortuzar, Leonardo Rundo, Maria Delgado-Ortet, Marika Reinius, Lucian Beer, Ramona Woitek, Stephan Ursprung, Helen Addley, James D Brenton, Florian Markowetz, Evis Sala
Aug 21, 2020
BACKGROUND: Ovarian cancer survival rates have not changed in the last 20 years. The majority of cases are High-grade serous ovarian carcinomas (HGSOCs), which are typically diagnosed at an advanced stage with multiple...
Longitudinal monitoring of disease burden and response using ctDNA from dried blood spots in xenograft models.
Carolin M Sauer, Katrin Heider, Jelena Belic, Samantha E Boyle, James A Hall, Dominique-Laurent Couturier, Angela An, Aadhitthya Vijayaraghavan, Marika Av Reinius, Karen Hosking, Maria Vias, Nitzan Rosenfeld, James D Brenton
Jun 13, 2022
Whole-genome sequencing (WGS) of circulating tumour DNA (ctDNA) is now a clinically important biomarker for predicting therapy response, disease burden and disease progression. However, the translation of ctDNA monitoring into...
Ultrasound-guided targeted biopsies of CT-based radiomic tumour habitats
Lucian Beer, Paula Martin-Gonzalez, Maria Delgado-Ortet, Marika Reinius, Leonardo Rundo, Ramona Woitek, Stephan Ursprung, Lorena Escudero, Hilal Sahin, Ionut-Gabriel Funingana, Joo-Ern Ang, Mercedes Jimenez-Linan, Tristan Lawton, Gaurav Phadke, Sally Davey, Nghia Q. Nguyen, Florian Markowetz, James D. Brenton, Mireia Crispin-Ortuzar, Helen Addley, Evis Sala
May 20, 2021
Ultrasound-guided targeted biopsies of CT-based radiomic tumour habitats
Lucian Beer, Paula Martin-Gonzalez, Maria Delgado-Ortet, Marika Reinius, Leonardo Rundo, Ramona Woitek, Stephan Ursprung, Lorena Escudero, Hilal Sahin, Ionut-Gabriel Funingana, Joo-Ern Ang, Mercedes Jimenez-Linan, Tristan Lawton, Gaurav Phadke, Sally Davey, Nghia Q Nguyen, Florian Markowetz, James D Brenton, Mireia Crispin-Ortuzar, Helen Addley, Evis Sala
Dec 02, 2020
Thermal comfort in desert refugee camps
Long-term encampment is a growing aspect of a growing refugee crisis. There is hence the need to ensure shelters provide a safe and suitable environment. We present the first field study including social and thermal comfort...
Clinically Interpretable Radiomics-Based Prediction of Histopathologic Response to Neoadjuvant Chemotherapy in High-Grade Serous Ovarian Carcinoma.
Leonardo Rundo, Lucian Beer, Lorena Escudero Sanchez, Mireia Crispin-Ortuzar, Marika Reinius, Cathal McCague, Hilal Sahin, Vlad Bura, Roxana Pintican, Marta Zerunian, Stephan Ursprung, Iris Allajbeu, Helen Addley, Paula Martin-Gonzalez, Thomas Buddenkotte, Naveena Singh, Anju Sahdev, Ionut-Gabriel Funingana, Mercedes Jimenez-Linan, Florian Markowetz, James D Brenton, Evis Sala, Ramona Woitek
Jun 30, 2022
BACKGROUND: Pathological response to neoadjuvant treatment for patients with high-grade serous ovarian carcinoma (HGSOC) is assessed using the chemotherapy response score (CRS) for omental tumor deposits. The main limitation of...
A field study of indoor thermal comfort in the subtropical highland climate of Bogota, Colombia
This paper undertakes the first field study of indoor thermal comfort in Colombia. The objective of this study was to compare thermal comfort data gathered in office buildings in Bogota, Colombia with the predictions made by...
The effect of real-time context-aware feedback on occupants' heating behaviour and thermal adaptation
Studies have shown that building energy demand in identical dwellings could vary by a factor of three. Differences in occupant behaviour – i.e. purchase, operation and maintenance – have been implicated as a strong source of...
Probabilistic adaptive thermal comfort for resilient design
Adaptive thermal comfort theory has become the bedrock of much thinking about how to judge if a free-running environment is suitable for human occupation. In design work, the conditions predicted by a thermal model, when the...
A field study of indoor thermal comfort in the subtropical highland climate of Bogota, Colombia
This paper undertakes the first field study of indoor thermal comfort in Colombia. The objective of this study was to compare thermal comfort data gathered in office buildings in Bogota, Colombia with the predictions made by...
Thermal comfort in desert refugee camps
Long-term encampment is a growing aspect of a growing refugee crisis. There is hence the need to ensure shelters provide a safe and suitable environment. We present the first field study including social and thermal comfort...
The influence of relative humidity on adaptive thermal comfort
Buildings generate nearly 30% of global carbon emissions, primarily due to the need to heat or cool them to meet acceptable indoor temperatures. In the last 20 years, the empirically derived adaptive model of thermal comfort has...
The influence of relative humidity on adaptive thermal comfort
Buildings generate nearly 30% of global carbon emissions, primarily due to the need to heat or cool them to meet acceptable indoor temperatures. In the last 20 years, the empirically derived adaptive model of thermal comfort has...
Supporting data on combined transcriptomic and phosphoproteomic analysis of BMP4 signaling in human embryonic stem cells.
Angelos Papadopoulos, Varvara Chalmantzi, Marko Hyvönen, Dimitris Stellas, Marika Syrrou, Theodore Fotsis, Carol Murphy
Apr 23, 2021
Human embryonic stem cells exhibit great potential as a therapeutic tool in regenerative medicine due to their self-renewal and trilineage differentiation capacity. Maintaining this unique cellular state has been shown to rely...
Probabilistic adaptive thermal comfort for resilient design
Adaptive thermal comfort theory has become the bedrock of much thinking about how to judge if a free-running environment is suitable for human occupation. In design work, the conditions predicted by a thermal model, when the...
The effect of real-time context-aware feedback on occupants' heating behaviour and thermal adaptation
Studies have shown that building energy demand in identical dwellings could vary by a factor of three. Differences in occupant behaviour – i.e. purchase, operation and maintenance – have been implicated as a strong source of...
Monthlong Intubated Patient with Life-Threatening COVID-19 and Cerebral Microbleeds Suffers Only Mild Cognitive Sequelae at 8-Month Follow-up
Linda Backman, Marika C Möller, Eric P Thelin, Daniel Dahlgren, Catharina Deboussard, Gunilla Östlund, Maria Lindau
Nov 15, 2021
OBJECTIVE: To elaborate on possible cognitive sequelae related to COVID-19, associated cerebrovascular injuries as well as the general consequences from intensive care. COVID-19 is known to have several, serious CNS-related...
Electrophysiological evidence of sustained spatial attention effects over anterior cortex
Marika Berchicci, Antonia Francisca Ten Brink, Federico Quinzi, Rinaldo Livio Perri, Donatella Spinelli, Francesco Di Russo
Jul 01, 2019
Spatial attention can improve performance in terms of speed and accuracy; this advantage may be mediated by brain processes at both poststimulus (reactive) and prestimulus (proactive) stages. Here, we studied how visuospatial...
anterior insula Event-related potentials Prefrontal Cortex sustained spatial attention /dk/atira/pure/subjectarea/asjc/2800/2800 name=General Neuroscience /dk/atira/pure/subjectarea/asjc/3200/3206 name=Neuropsychology and Physiological Psychology /dk/atira/pure/subjectarea/asjc/3200/3205 name=Experimental and Cognitive Psychology /dk/atira/pure/subjectarea/asjc/2800/2807 name=Endocrine and Autonomic Systems /dk/atira/pure/subjectarea/asjc/2800/2806 name=Developmental Neuroscience /dk/atira/pure/subjectarea/asjc/2800/2805 name=Cognitive Neuroscience /dk/atira/pure/subjectarea/asjc/2800/2803 name=Biological Psychiatry
Electrophysiological evidence of sustained spatial attention effects over anterior cortex
Marika Berchicci, Antonia Francisca Ten Brink, Federico Quinzi, Rinaldo Livio Perri, Donatella Spinelli, Francesco Di Russo
Jul 01, 2019
Spatial attention can improve performance in terms of speed and accuracy; this advantage may be mediated by brain processes at both poststimulus (reactive) and prestimulus (proactive) stages. Here, we studied how visuospatial...
anterior insula Event-related potentials Prefrontal Cortex sustained spatial attention /dk/atira/pure/subjectarea/asjc/2800/2800 name=General Neuroscience /dk/atira/pure/subjectarea/asjc/3200/3206 name=Neuropsychology and Physiological Psychology /dk/atira/pure/subjectarea/asjc/3200/3205 name=Experimental and Cognitive Psychology /dk/atira/pure/subjectarea/asjc/2800/2807 name=Endocrine and Autonomic Systems /dk/atira/pure/subjectarea/asjc/2800/2806 name=Developmental Neuroscience /dk/atira/pure/subjectarea/asjc/2800/2805 name=Cognitive Neuroscience /dk/atira/pure/subjectarea/asjc/2800/2803 name=Biological Psychiatry
An unbiased assessment of the role of imprinted genes in an intergenerational model of developmental programming.
Elizabeth J Radford, Elvira Isganaitis, Josep Jimenez-Chillaron, Joshua Schroeder, Michael Molla, Simon Andrews, Nathalie Didier, Marika Charalambous, Kirsten McEwen, Giovanna Marazzi, David Sassoon, Mary-Elizabeth Patti, Anne C Ferguson-Smith
Dec 02, 2020
Environmental factors during early life are critical for the later metabolic health of the individual and of future progeny. In our obesogenic environment, it is of great socioeconomic importance to investigate the mechanisms...
Overheating in vulnerable and non-vulnerable households
Marika Vellei, Alfonso P. Ramallo Gonzalez, David Coley, Jeehang Lee, Elizabeth Gabe-Thomas, Thomas Lovett, Sukumar Natarajan
Jan 01, 0001
As the 2003 European heatwave demonstrated, overheating in homes can cause wide-scale fatalities. With temperatures and heatwave frequency predicted to increase due to climate change, such events can be expected to become more...
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