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Neuroarthropathy in diabetes
Charcot neuroarthropathy is a rare but serious complication of diabetes, causing progressive destruction of the bones and joints of the foot leading to deformity, altered biomechanics and an increased risk of ulceration....
HGVA
Javier Lopez, Jacobo Coll, Matthias Haimel, Swaathi Kandasamy, Joaquin Tarraga, Pedro Furio-Tari, Wasim Bari, Marta Bleda, Antonio Rueda, Stefan Gräf, Augusto Rendon, Joaquin Dopazo, Ignacio Medina
Aug 18, 2017
High-profile genomic variation projects like the 1000 Genomes project or the Exome Aggregation Consortium, are generating a wealth of human genomic variation knowledge which can be used as an essential reference for identifying...
Autobiography and history on screen
Rebecca Coll
May 24, 2016
Pro-Environmental Behaviour of EU Citizens
This article examines the pro-environmental behaviour of EU citizens and the potential connection with their attitudes towards common environmental legislation and environmental standards. It analyses factors of the...
IT Policy & Standardization Computer Science and Information Technology IT Policy and Standardization
Published by: IGI Global Scientific Publishing
Effectiveness of different accelerated partial breast irradiation techniques for the treatment of breast cancer patients
Gustavo Nader Marta, Jessica Barrett, Gustavo José Martiniano Porfirio, Ana Luiza Cabrera Martimbianco, José Luiz Barbosa Bevilacqua, Philip Poortmans, Rachel Riera
Feb 11, 2019
AIM: This systematic review was conducted to compare the effectiveness of different accelerated partial breast irradiation (APBI) techniques for the treatment of breast cancer patients. BACKGROUND: Numerous (APBI) techniques are...
Local Persistence of Novel MRSA Lineage after Hospital Ward Outbreak, Cambridge, UK, 2011–2013
Bacteria Cambridge MRSA Staphylococcus aureus United Kingdom infection control nosocomial staphylococci Cross Infection Disease Outbreaks Genome Bacterial History 21st Century Humans Methicillin-Resistant Staphylococcus aureus Phylogeny Polymorphism Single Nucleotide Staphylococcal Infections United Kingdom
Aptamer-modified gold nanoparticles for rapid aggregation-based detection of inflammation
Susan Giorgi-Coll, María J Marín, Olajumoke Sule, Peter J Hutchinson, Keri LH Carpenter
Dec 04, 2019
Pathophysiology of chronic subdural haematoma
Ellie Edlmann, Susan Giorgi-Coll, Peter C Whitfield, Keri LH Carpenter, Peter J Hutchinson
May 31, 2017
POMC
Pro-opiomelanocortin (POMC) is the archetypal polypeptide precursor of hormones and neuropeptides. In this review, we examine the variability in the individual peptides produced in different tissues and the impact of the...
Mapping Local Perceptions for the Planning of Cultural Landscapes
Local perceptions in the definition of cultural landscapes have been on the radar of the scientific community for a long time, but very few studies have focused on integrating this information into heritage and planning...
Published by: IGI Global Scientific Publishing
Succinate supplementation improves metabolic performance of mixed glial cell cultures with mitochondrial dysfunction
Mitochondrial dysfunction, the inability to efficiently utilise metabolic fuels and oxygen, contributes to pathological changes following traumatic spinal cord or traumatic brain injury (TBI). In the present study, we tested the...
Local Knowledge Management and Innovation Spillover
Tourism lifestyle entrepreneurs play an essential role in the innovation and competitiveness of tourist destinations. However, existing knowledge about the determinants of the innovation they generate is far from being fully...
Published by: IGI Global Scientific Publishing
Analysis of Standards, Certifications and Labels for Bio-based Products in the Context of Sustainable Bioeconomy
Bioeconomy has been proposed as a pathway to sustainable development in many countries. However, the difficulties in defining the bioeconomy boundaries at the national level might necessitate the adoption of a sectoral approach...
IT Policy & Standardization Computer Science and Information Technology IT Policy and Standardization
Published by: IGI Global Scientific Publishing
Aptamer-modified gold nanoparticles for rapid aggregation-based detection of inflammation
Susan Giorgi-Coll, María J. Marín, Olajumoke Sule, Peter J. Hutchinson, Keri L.H. Carpenter
Jun 06, 2020
Abstract: A proof-of-concept aptamer-based optical assay is described for the determination of the immuno signalling molecule interleukin-6 (IL-6), a key marker of acute inflammation. The optical assay is based on the...
Peripheral mechanisms contributing to the glucocorticoid hypersensitivity in proopiomelanocortin null mice treated with corticosterone.
Zoi Michailidou, Anthony P Coll, Christopher J Kenyon, Nicholas M Morton, Stephen O'Rahilly, Jonathan R Seckl, Karen E Chapman
Jan 18, 2021
Proopiomelanocortin (POMC) deficiency causes severe obesity through hyperphagia of hypothalamic origin. However, low glucocorticoid levels caused by adrenal insufficiency mitigate against insulin resistance, hyperphagia and fat...
Closed-loop insulin delivery in end-of-life care
BACKGROUND: Glucose management for people with diabetes approaching the end of life can be very challenging. The aim is to balance a minimally invasive approach with avoidance of symptomatic hypo- and hyperglycaemia. CASE...
Aptamer-modified gold nanoparticles for rapid aggregation-based detection of inflammation
Susan Giorgi-Coll, María J Marín, Olajumoke Sule, Peter J Hutchinson, Keri L H Carpenter
Jan 06, 2020
A proof-of-concept aptamer-based optical assay is described for the determination of the immuno signalling molecule interleukin-6 (IL-6), a key marker of acute inflammation. The optical assay is based on the aggregation of gold...
Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity
TR Flint, T Janowitz, CM Connell, EW Roberts, AE Denton, AP Coll, DI Jodrell, DT Fearon
Dec 20, 2016
Closed-loop insulin delivery in inpatients with type 2 diabetes
Hood Thabit, Sara Hartnell, Janet M Allen, Andrea Lake, Malgorzata E Wilinska, Yue Ruan, Mark L Evans, Anthony P Coll, Roman Hovorka
Nov 10, 2016
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