Quantitative modeling of human liver reveals dysregulation of glycosphingolipid pathways in nonalcoholic fatty liver disease.
Partho Sen,
Olivier Govaere,
Tim Sinioja,
Aidan McGlinchey,
Dawei Geng,
Vlad Ratziu,
Elisabetta Bugianesi,
Jörn M Schattenberg,
Antonio Vidal-Puig,
Michael Allison,
Simon Cockell,
Ann K Daly,
Tuulia Hyötyläinen,
Quentin M Anstee,
Matej Orešič
Oct 06, 2022
Nonalcoholic fatty liver disease (NAFLD) is an increasingly prevalent disease that is associated with multiple metabolic disturbances, yet the metabolic pathways underlying its progression are poorly understood. Here, we studied...