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Results: 131
Free water imaging of the cholinergic system in dementia with Lewy bodies and Alzheimer's disease.
Julia Schumacher, Nicola J Ray, Calum A Hamilton, Maurizio Bergamino, Paul C Donaghy, Michael Firbank, Rosie Watson, Gemma Roberts, Louise Allan, Nicola Barnett, John T O'Brien, Alan J Thomas, John-Paul Taylor
Mar 15, 2023
INTRODUCTION: Degeneration of cortical cholinergic projections from the nucleus basalis of Meynert (NBM) is characteristic of dementia with Lewy bodies (DLB) and Alzheimer's disease (AD), whereas involvement of cholinergic...
Major Events, Big Facilities
Let us imagine a large sports facility and an integrated system to control its maintenance (structures, facilities, furnishings, communication systems), pre-configure temporary set-ups, procurement of goods and materials, check...
Virtual Communities & Virtual Reality Social Sciences and Humanities Human Aspects of Technology Computer Science and Information Technology Media and Communications
Published by: IGI Global Scientific Publishing
Digital Intelligences and Urban InfoSystems in Territorial Re-Education
The relationship between education and urban environments identifies a process of societal impact through levels of exploration and knowledge of the territorial system. It emerges from pedagogical levels linked to the...
Global Information Technology Computer Science and Information Technology Global Information Technology Physical Sciences and Engineering Business and Management
Published by: IGI Global Scientific Publishing
Structure-Function Analysis of Insect Olfactory Receptors
Maurizio Pellegrino
Jan 01, 0001
Organisms use their senses to transform external stimuli into an internal representation of the world. Insects employ their keen sense of smell for a variety of tasks including location of food sources, which can vary from yeast...
Published by: Rockefeller University
Bone Marrow Stromal Cells Drive Key Hallmarks of B Cell Malignancies.
All B cell leukaemias and a substantial fraction of lymphomas display a natural niche residency in the bone marrow. While the bone marrow compartment may only be one of several sites of disease manifestations, the strong...
Bone Marrow Stromal Cells Drive Key Hallmarks of B Cell Malignancies.
All B cell leukaemias and a substantial fraction of lymphomas display a natural niche residency in the bone marrow. While the bone marrow compartment may only be one of several sites of disease manifestations, the strong...
Published by: International journal of molecular sciences
Bone Marrow Stromal Cells Drive Key Hallmarks of B Cell Malignancies
All B cell leukaemias and a substantial fraction of lymphomas display a natural niche residency in the bone marrow. While the bone marrow compartment may only be one of several sites of disease manifestations, the strong...
Conduction and Gating Properties of the TRAAK Channel from Molecular Dynamics Simulations with Different Force Fields
Riccardo Ocello, Simone Furini, Francesca Lugli, Maurizio Recanatini, Carmen Domene, Matteo Masetti
Dec 28, 2020
In recent years, the K2P family of potassium channels has been the subject of intense research activity. Owing to the complex function and regulation of this family of ion channels, it is common practice to complement...
Macroautophagy without LC3 conjugation?
A recent study makes the surprising observation that autophagosomes can still form in the absence of the core conjugation machinery. Furthermore, while such autophagosomes can fuse with lysosomes, their degradation is delayed...
Particle Generative Adversarial Networks for full-event simulation at the LHC and their application to pileup description
Jesus Arjona Martínez, Thong Q Nguyen, Maurizio Pierini, Maria Spiropulu, Jean-Roch Vlimant
Jul 07, 2020
Abstract: We investigate how a Generative Adversarial Network could be used to generate a list of particle four-momenta from LHC proton collisions, allowing one to define a generative model that could abstract from the...
Particle Generative Adversarial Networks for full-event simulation at the LHC and their application to pileup description
Abstract
We investigate how a Generative Adversarial Network could be used to generate a list of particle four-momenta from LHC proton collisions, allowing one to define a...
Jesus Arjona Martínez, Thong Q Nguyen, Maurizio Pierini, Maria Spiropulu, Jean-Roch Vlimant
Jul 07, 2020
White-Matter Hyperintensity Load and Differences in Resting-State Network Connectivity Based on Mild Cognitive Impairment Subtype.
Martina Vettore, Matteo De Marco, Claudia Pallucca, Matteo Bendini, Maurizio Gallucci, Annalena Venneri
Oct 21, 2021
"Mild cognitive impairment" (MCI) is a diagnosis characterised by deficits in episodic memory (aMCI) or in other non-memory domains (naMCI). Although the definition of subtypes is helpful in clinical classification, it provides...
Conduction and Gating Properties of the TRAAK Channel from Molecular Dynamics Simulations with Different Force Fields
Riccardo Ocello, Simone Furini, Francesca Lugli, Maurizio Recanatini, Carmen Domene, Matteo Masetti
Dec 28, 2020
In recent years, the K2P family of potassium channels has been the subject of intense research activity. Owing to the complex function and regulation of this family of ion channels, it is common practice to complement...
Particle Generative Adversarial Networks for full-event simulation at the LHC and their application to pileup description
Abstract
We investigate how a Generative Adversarial Network could be used to generate a list of particle four-momenta from LHC proton collisions, allowing one to define a...
Jesus Arjona Martínez, Thong Q Nguyen, Maurizio Pierini, Maria Spiropulu, Jean-Roch Vlimant
Feb 11, 2022
XIAP and cIAP1 amplifications induce Beclin 1-dependent autophagy through NFκB activation.
Fang Lin, Ghita Ghislat, Shouqing Luo, Maurizio Renna, Farah Siddiqi, David C Rubinsztein
May 05, 2015
Genetic predisposition to hemophagocytic lymphohistiocytosis
Valentina Cetica, Elena Sieni, Daniela Pende, Cesare Danesino, Carmen De Fusco, Franco Locatelli, Concetta Micalizzi, Maria Caterina Putti, Andrea Biondi, Franca Fagioli, Lorenzo Moretta, Gillian M Griffiths, Lucio Luzzatto, Maurizio Aricò
Jan 22, 2016
Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3.
Fiona M Menzies, Jeannette Huebener, Maurizio Renna, Michael Bonin, Olaf Riess, David C Rubinsztein
Aug 13, 2014
Co-infection and ICU-acquired infection in COIVD-19 ICU patients
P2Y12 inhibitors for the neurointerventionalist.
Robin J Borchert, Davide Simonato, Charlotte R Hickman, Maurizio Fuschi, Lucie Thibault, Hans Henkes, David Fiorella, Benjamin YQ Tan, Leonard LL Yeo, Hegoda L D Makalanda, Ken Wong, Pervinder Bhogal
Mar 08, 2022
The use of antiplatelets is widespread in clinical practice. However, for neurointerventional procedures, protocols for antiplatelet use are scarce and practice varies between individuals and institutions. This is further...
Intersect-then-combine approach
Maurizio Callari, Stephen-John Sammut, Leticia De Mattos-Arruda, Alejandra Bruna, Oscar M Rueda, Suet-Feung Chin, Carlos Caldas
May 05, 2017
Bioinformatic analysis of genomic sequencing data to identify somatic mutations in cancer samples is far from achieving the required robustness and standardisation. In this study we generated a whole exome sequencing benchmark...
BWA Filtering Mutect2 NA12878 Novoalign Platinum genome Somatic mutation Strelka Variant calling Whole exome sequencing Algorithms Computational Biology DNA Neoplasm Exome Genome Human Humans INDEL Mutation Mutation Neoplasms Polymorphism Single Nucleotide Sensitivity and Specificity Sequence Analysis DNA
Rapamycin rescues mitochondrial myopathy via coordinated activation of autophagy and lysosomal biogenesis.
Gabriele Civiletto, Sukru Anil Dogan, Raffaele Cerutti, Gigliola Fagiolari, Maurizio Moggio, Costanza Lamperti, Cristiane Benincá, Carlo Viscomi, Massimo Zeviani
Dec 17, 2018
The mTOR inhibitor rapamycin ameliorates the clinical and biochemical phenotype of mouse, worm, and cellular models of mitochondrial disease, via an unclear mechanism. Here, we show that prolonged rapamycin treatment improved...
Autophagy lysosomal biogenesis mTORC1 mitochondrial disease rapamycin Animals Autophagy Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Electron Transport Complex IV Lysosomes Mice Inbred C57BL Mice Knockout Mitochondria Mitochondrial Myopathies Motor Activity Muscles Organelle Biogenesis Phenotype Rilmenidine Sirolimus TOR Serine-Threonine Kinases
Diffusional Kurtosis Imaging in the Diffusion Imaging in Python Project.
Rafael Neto Henriques, Marta M Correia, Maurizio Marrale, Elizabeth Huber, John Kruper, Serge Koudoro, Jason D Yeatman, Eleftherios Garyfallidis, Ariel Rokem
Sep 13, 2021
Diffusion-weighted magnetic resonance imaging (dMRI) measurements and models provide information about brain connectivity and are sensitive to the physical properties of tissue microstructure. Diffusional Kurtosis Imaging (DKI)...
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