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Results: 22175
Neutralizing monoclonal antibodies block human immunodeficiency virus type 1 infection of dendritic cells and transmission to T cells
Prevention of the initial infection of mucosal dendritic cells (DC) and interruption of the subsequent transmission of HIV-1 from DC to T cells are likely to be important attributes of an effective human immunodeficiency virus...
Published by: Rockefeller University
A quantitative determination of lipid bilayer deposition efficiency using AFM.
The efficacy of a number of different methods for depositing a dimyristoylphosphatidylcholine (DMPC) lipid bilayer or DMPC-cholesterol (3 : 1) mixed bilayer onto a silicon substrate has been investigated in a quantitative manner...
Michael Heidelberger, 1933
The Rockefeller University
Jan 01, 0001
Dr. Michael Heidelberger. Contributions of Chemistry of the Knowledge of Immune Processes
Lecture delivered March 17th, 1933
Posted with permission
Published by: The William & Wilkins Company
Remembering Michael Shute
Dedication to Michael Shute.
Published by: Memorial University of Newfoundland
Thermal Behaviour of Synovene and Oleamide in Oil Adsorbed on Steel
Michael T. L. Casford, Debashis Puhan, Paul B. Davies, Gareth L. Bracchi, Tony D. Smith
Jun 25, 2020
Abstract: Oleamide and Synovene lubricant additives when mixed together show a clear co-operative effect leading to friction and wear reduction. Sum Frequency Generation vibrational spectroscopy has been used to record in situ...
Review of: Karen Hunger Parshall, Michael T. Walton and Bruce T. Moran (eds.), Bridging Traditions
S Fransen
Mar 04, 2019
This collected volume is written in honour of Allen G. Debus (1926–2009), the famous historian of science. Trained as a chemist, his interest in the history of science and chemistry would guide his research and his output. As...
Thermal Behaviour of Synovene and Oleamide in Oil Adsorbed on Steel
Michael T. L. Casford, Debashis Puhan, Paul B. Davies, Gareth L. Bracchi, Tony D. Smith
Jun 06, 2020
Abstract: Oleamide and Synovene lubricant additives when mixed together show a clear co-operative effect leading to friction and wear reduction. Sum Frequency Generation vibrational spectroscopy has been used to record in situ...
Restriction endonuclease TseI cleaves A:A and T
Long Ma, Kai Chen, David J Clarke, Christopher P Nortcliffe, Geoffrey G Wilson, J Michael Edwardson, A Jennifer Morton, Anita C Jones, David TF Dryden
Feb 13, 2020
The type II restriction endonuclease TseI recognizes the DNA target sequence 5'-G^CWGC-3' (where W = A or T) and cleaves after the first G to produce fragments with three-base 5'-overhangs. We have determined that it is a...
JEFFREY RAVETCH AND MICHAEL YOUNG
The Rockefeller University
Jan 01, 0001
Congratulations to Jeffrey Ravetch and Michael Young, recipients of the 2012 Canada Gairdner International Award
Published by: The Rockefeller University
Remembering Michael Shute
Dedication to Michael Shute.
Published by: Memorial University of Newfoundland
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
Rigid analytic quantum groups and quantum Arens-Michael envelopes
Nicolas Dupré
Aug 19, 2019
We introduce a rigid analytification of the quantized coordinate algebra of a semisimple algebraic group and a quantized Arens-Michael envelope of the enveloping algebra of the corresponding Lie algebra, working over a...
Extracellular Lactate
James T Grist, Lorna B Jarvis, Zoya Georgieva, Sara Thompson, Harpreet Kaur Sandhu, Keith Burling, Ashley Clarke, Sarah Jackson, Mark Wills, Ferdia A Gallagher, Joanne L Jones
Feb 23, 2018
Following activation, T cells rapidly divide and acquire effector functions. This energetically demanding process depends upon the ability of T cells to undergo metabolic remodeling from oxidative phosphorylation to aerobic...
B-hadron production in NNLO QCD
We calculate, for the first time, the NNLO QCD corrections to identified
heavy hadron production at hadron colliders. The calculation is based on a
flexible numeric framework which allows the calculation of any distribution of
a...
Using hybrid atomic force microscopy and infrared spectroscopy (AFM‐IR) to identify chemical components of the hair medulla on the nanoscale
Abstract: Atomic force microscopy integrated with infrared spectroscopy (AFM‐IR) has been used to topographically and chemically examine the medulla of human hair fibres with nanometre scale lateral resolution. The mapping of...
Published by: Journal of Microscopy
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
A Novel Framework Using Zero Shot Learning Technique for a Non-Factoid Question Answering System
Non-Factoid Question Answering (QA) is the next generation of textual QA systems, which gives passage level summaries for a natural language query, posted by the user. The main issue lies in the appropriateness of the generated...
Published by: IGI Global Scientific Publishing
Evidence both L-type and non-L-type voltage-dependent calcium channels contribute to cerebral artery vasospasm following loss of NO in the rat
We recently found block of NO synthase in rat middle cerebral artery caused spasm, associated with depolarizing oscillations in membrane potential (E-m) similar in form but faster in frequency (circa 1 Hz) to vasomotion. T-type...
Voltage-activated Ca<sup>2+</sup> channels in rat renal afferent and efferent myocytes
AIMS: Based on indirect methods, it has been suggested that both L- and T-type Ca(2+) channels mediate signalling in the renal afferent arteriole and that T-type Ca(2+) channels are involved in signalling in the efferent...
Evidence both L-type and non-L-type voltage-dependent calcium channels contribute to cerebral artery vasospasm following loss of NO in the rat
We recently found block of NO synthase in rat middle cerebral artery caused spasm, associated with depolarizing oscillations in membrane potential (E-m) similar in form but faster in frequency (circa 1 Hz) to vasomotion. T-type...
Organocatalytic Enantioselective Sulfa-Michael Additions to α,β-Unsaturated Diazoketones
Patricia B Momo, Eduardo F Mizobuchi, Radell Echemendía, Isabel Baddeley, Matthew N Grayson, Antonio C B Burtoloso
Mar 04, 2022
Enantioselective sulfa-Michael additions to α,β unsaturated diazocarbonyl compounds have been developed. Quinine-derived squaramide was found to be the best catalyst to promote C-S bond formation in a highly stereoselective...
Rapid sensing of l-leucine by human and murine hypothalamic neurons
Nicholas Heeley, Peter Kirwan, Tamana Darwish, Marion Arnaud, Mark L Evans, Florian T Merkle, Frank Reimann, Fiona M Gribble, Clemence Blouet
Apr 05, 2018
OBJECTIVE: Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain, and adiposity. However, little is known about the mechanisms by which...
The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling.
Donald T Gracias, Erietta Stelekati, Jennifer L Hope, Alina C Boesteanu, Travis A Doering, Jillian Norton, Yvonne M Mueller, Joseph A Fraietta, E John Wherry, Martin Turner, Peter D Katsikis
Aug 14, 2019
We found upregulation of expression of the microRNA miR-155 in primary effector and effector memory CD8(+) T cells, but low miR-155 expression in naive and central memory cells. Antiviral CD8(+) T cell responses and viral...
Animals CD8-Positive T-Lymphocytes Cell Proliferation Flow Cytometry Gene Expression Profiling Gene Regulatory Networks Immunoblotting Immunologic Memory Interferon Regulatory Factor-7 Interferons Mice Mice Inbred C57BL Mice Knockout MicroRNAs Oligonucleotide Array Sequence Analysis Orthomyxoviridae Orthomyxoviridae Infections RNA Interference Reverse Transcriptase Polymerase Chain Reaction STAT1 Transcription Factor Signal Transduction Suppressor of Cytokine Signaling 1 Protein Suppressor of Cytokine Signaling Proteins
Voltage-activated Ca<sup>2+</sup> channels in rat renal afferent and efferent myocytes
AIMS: Based on indirect methods, it has been suggested that both L- and T-type Ca(2+) channels mediate signalling in the renal afferent arteriole and that T-type Ca(2+) channels are involved in signalling in the efferent...
The Herschel census of infrared SEDs through cosmic time
M. Symeonidis, M. Vaccari, S. Berta, M. J. Page, D. Lutz, V. Arumugam, H. Aussel, J. Bock, A. Boselli, V. Buat, P. L. Capak, D. L. Clements, A. Conley, L. Conversi, A. Cooray, C. D. Dowell, D. Farrah, A. Franceschini, E. Giovannoli, J. Glenn, M. Griffin, E. Hatziminaoglou, H.-S. Hwang, E. Ibar, O. Ilbert, R. J. Ivison, E.~L. Floc'h, S. Lilly, J. S. Kartaltepe, B. Magnelli, G. Magdis, L. Marchetti, H. T. Nguyen, R. Nordon, B. O'Halloran, S. J. Oliver, A. Omont, A. Papageorgiou, H. Patel, C. P. Pearson, I. Pérez-Fournon, M. Pohlen, P. Popesso, F. Pozzi, D. Rigopoulou, L. Riguccini, D. Rosario, I. G. Roseboom, M. Rowan-Robinson, M. Salvato, B. Schulz, D. Scott, N. Seymour, D. L. Shupe, A. J. Smith, I. Valtchanov, L. Wang, C. K. Xu, M. Zemcov, S. Wuyts
May 21, 2013
Using Herschel data from the deepest SPIRE and PACS surveys (HerMES and PEP) in COSMOS, GOODS-S and GOODS-N, we examine the dust properties of infrared (IR)-luminous (LIR > 1010 L⊙) galaxies at 0.1 < z < 2 and determine...
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