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Possibilities and limits of social accountability
This paper examines the possibilities and limits of social accountability, characterized by face-to-face interactions between organizational actors and beneficiary others. We explore how social accountability is produced in and...
A Systematic Literature Review on 30 Years of Empirical Research on Information Systems Business Value
Information Systems Business Value (ISBV) has been a key research topic for the IS research community. While the vast majority of ISBV research demonstrates the positive relationship between IS and firm performance, the...
Published by: IGI Global Scientific Publishing
The damage-associated molecular pattern HMGB1 is released early after clinical hepatic ischemia/reperfusion.
Rowan F van Golen, Megan J Reiniers, Gerben Marsman, Lindy K Alles, Derrick M van Rooyen, Björn Petri, Vincent A Van der Mark, Adriaan A Van Beek, Ben Meijer, Martinus A Maas, Sacha Zeerleder, Joanne Verheij, Geoffrey C Farrell, Brenda M Luken, Narci C Teoh, Thomas M van Gulik, Michael P Murphy, Michal Heger
Feb 12, 2019
OBJECTIVE AND BACKGROUND: Activation of sterile inflammation after hepatic ischemia/reperfusion (I/R) culminates in liver injury. The route to liver damage starts with mitochondrial oxidative stress and cell death during early...
antioxidants Damage-associated molecular patterns Intravital Microscopy Liver resection Mitochondrial DNA Sterile inflammation Aged Alarmins antioxidants Cytokines DNA Mitochondrial Female HMGB1 Protein Humans Liver Male Middle Aged Mitochondria Organophosphorus Compounds Oxidative Stress Reperfusion Injury Ubiquinone
Investigation into the role of the germline epigenome in the transmission of glucocorticoid-programmed effects across generations.
Jessy Cartier, Thomas Smith, John P Thomson, Catherine M Rose, Batbayar Khulan, Andreas Heger, Richard R Meehan, Amanda J Drake
Sep 08, 2018
BACKGROUND: Early life exposure to adverse environments affects cardiovascular and metabolic systems in the offspring. These programmed effects are transmissible to a second generation through both male and female lines...
DNA Methylation Early life programming epigenetic Germline transmission Glucocorticoids Histone modifications small RNA Animals Birth Weight DNA Methylation Dexamethasone Epigenesis Genetic Female Glucocorticoids Histone Code Male Maternal Exposure RNA Small Untranslated Rats Sprague-Dawley Spermatozoa
Gap variability upon packing in organic photovoltaics.
The variation of the HOMO-LUMO band gap is explored for varying packing arrangements of the 4mod BT-4TIC donor-acceptor molecule pair, by means of a high-throughput ab-initio random structure search of packing possibilities. 350...
Teaching Medical Students About Attention Deficit Hyperactivity Disorder (ADHD)
In this paper, we describe how an e-learning resource on Attention Deficit Hyperactivity Disorder (ADHD) for medical students was designed and developed. The aim of the resource was to provide students with essential knowledge...
Inhibition of proteasome rescues a pathogenic variant of respiratory chain assembly factor COA7.
An Integrated Neural Framework for Dynamic and Static Face Processing.
Faces convey rich information including identity, gender and expression. Current neural models of face processing suggest a dissociation between the processing of invariant facial aspects such as identity and gender, that engage...
Chiral soliton predictions for exotic baryons.
We re-analyze the predictions of chiral-soliton models for the masses and
decay widths of baryons in the exotic antidecuplet of flavour SU(3). The calculated
ranges of the chiral-soliton moment of inertia and the π-nucleon...
Published by: HEP, Cavendish Laboratory, University of Cambridge
NNLO QCD corrections to three-photon production at the LHC
Abstract: We compute the NNLO QCD corrections to three-photon production at the LHC. This is the first NNLO QCD calculation for a 2 → 3 process. Our calculation is exact, except for the scale-independent part of the two-loop...
Assessment of the European Union's illicit trade agreements with the four major transnational tobacco companies
To address the illicit cigarette trade, the European Union (EU) has signed agreements with the four major Transnational Tobacco Companies (TTCs) that involve establishing extensive systems of cooperation. All agreements...
Co-registration of optoacoustic tomography and magnetic resonance imaging data from murine tumour models.
Marcel Gehrung, Michal Tomaszewski, Dominick McIntyre, Jonathan Disselhorst, Sarah Bohndiek
Mar 13, 2020
As optoacoustic tomography (OT) emerges as a mainstream pre-clinical imaging modality, understanding the relationship between optoacoustic and other imaging biomarkers in the context of the underlying tissue biology becomes...
Published by: Photoacoustics
Assessment of the European Union's illicit trade agreements with the four major transnational tobacco companies
To address the illicit cigarette trade, the European Union (EU) has signed agreements with the four major Transnational Tobacco Companies (TTCs) that involve establishing extensive systems of cooperation. All agreements...
Mitochondrial Genome Engineering
In recent years mitochondrial DNA (mtDNA) has transitioned to greater prominence across diverse areas of biology and medicine. The recognition of mitochondria as a major biochemical hub, contributions of mitochondrial...
RNA import mitoTALEN Mitochondria mtDNA mtZFN Animals Biolistics Biological Transport CRISPR-Cas Systems DNA Mitochondrial Dependovirus Endodeoxyribonucleases Gene Editing Genetic Vectors Genome Mitochondrial Mammals Mitochondria Polyribonucleotide Nucleotidyltransferase RNA Guide Kinetoplastida Transcription Activator-Like Effector Nucleases Transcription Factors
Minimising Energy in Construction
John Orr, Michal Drewniok, Ian Walker, Timothy Ibell, Alexander Copping, Stephen Emmitt
Jan 01, 2019
The built environment accounts for 39% of global energy related CO2 emissions, and construction generates 13% of global GDP. Recent success in reducing operational energy and the introduction of strict targets for near-zero...
Energy reduction with super-resolution convolutional neural network for ultrasound tomography
Daruisz Wójcik, Tomasz Rymarczyk, Bartosz Przysucha, Michal Golabek, Dariusz Majerek, Tomasz Warowny, Manuchehr Soleimani
Feb 01, 2023
This study addresses the issue of energy optimization by investigating solutions for the reduction of energy consumption in the diagnostics and monitoring of technological processes. The implementation of advanced process...
NNLO QCD corrections to three-photon production at the LHC
Abstract: We compute the NNLO QCD corrections to three-photon production at the LHC. This is the first NNLO QCD calculation for a 2 → 3 process. Our calculation is exact, except for the scale-independent part of the two-loop...
Modelling the embodied carbon cost of UK domestic building construction
The construction of new domestic properties contributes 2% of UK territorial greenhouse gas (GHG) emissions. The UK government aims to increase construction of new homes in England by almost a third, to 300,000 per year by...
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