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Iatrogenic antibody deficiency from B-cell targeted therapies in autoimmune rheumatic diseases.
B-cell targeted therapies (BCTT) are now widely used in autoimmune rheumatic diseases, including SLE, antineutrophil cytoplasmic antibody-associated vasculitis and rheumatoid arthritis. Early studies suggested that rituximab did...
Recommendations for the management of secondary hypogammaglobulinaemia due to B cell targeted therapies in autoimmune rheumatic diseases.
Sonali Wijetilleka, David R Jayne, Chetan Mukhtyar, Aftab Ala, Philip D Bright, Hector Chinoy, Lorraine Harper, Majid A Kazmi, Sorena Kiani-Alikhan, Charles K Li, Siraj A Misbah, Louise Oni, Fiona E Price-Kuehne, Alan D Salama, Sarita Workman, David Wrench, Mohammed Yousuf Karim
Nov 27, 2019
OBJECTIVES: The association of B cell targeted therapies with development of hypogammaglobulinaemia and infection is increasingly recognized. Our aim was to develop consensus recommendations for immunoglobulin replacement...
Contact line dynamics of gravity driven spreading of liquids
Abstract
The spreading dynamics of the gravity-driven liquid motion on an inclined solid surface was studied by considering two fundamental physical models: the molecular kinetic...
Immunoglobulin replacement for secondary immunodeficiency after B-cell targeted therapies in autoimmune rheumatic disease
Sonali Wijetilleka, Chetan Mukhtyar, David Jayne, Aftab Ala, Philip Bright, Hector Chinoy, Lorraine Harper, Majid Kazmi, Sorena Kiani-Alikhan, Charles Li, Siraj Misbah, Louise Oni, Fiona Price-Kuehne, Alan Salama, Sarita Workman, David Wrench, Mohammed Yousuf Karim
Feb 24, 2020
BACKGROUND: Consensus guidelines are not available for the use of immunoglobulin replacement therapy (IGRT) in patients developing iatrogenic secondary antibody deficiency following B-cell targeted therapy (BCTT) in autoimmune...
Epidemiology, clinical features, and impact of food habits on the risk of hepatocellular carcinoma
M Al-Amin Shawon, M Abul Khair Yousuf, Enayetur Raheem, Sium Ahmed, Tyeaba Tasnim Dipti, Mohammad Razuanul Hoque, Hiroaki Taniguchi, M Rezaul Karim
Apr 30, 2020
Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third most common cause of cancer mortality worldwide. Infection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV) is the most predominant cause of...
Contact line dynamics of gravity driven spreading of liquids
Abstract
The spreading dynamics of the gravity-driven liquid motion on an inclined solid surface was studied by considering two fundamental physical models: the molecular kinetic...
Contact line dynamics of gravity driven spreading of liquids
Abstract: The spreading dynamics of the gravity-driven liquid motion on an inclined solid surface was studied by considering two fundamental physical models: the molecular kinetic theory and the hydrodynamic theory (HDT). The...
Lack of attentional retraining effects in cigarette smokers attempting cessation
Rachna Begh, Marcus R Munafò, Saul Shiffman, Stuart G Ferguson, Linda Nichols, Mohammed A Mohammed, Roger L Holder, Stephen Sutton, Paul Aveyard
Jun 15, 2018
BACKGROUND: Observational studies have shown that attentional bias for smoking-related cues is associated with increased craving and relapse. Laboratory experiments have shown that manipulating attentional bias may change...
Influence of ethnicity on acceptability of method of blood pressure monitoring
Sally Wood, Sheila M Greenfield, M Sayeed Haque, Una Martin, Paramjit S Gill, Jonathan Mant, Mohammed A Mohammed, Gurdip Heer, Amanpreet Johal, Ramandeep Kaur, Claire Schwartz, Richard J McManus
May 02, 2018
BACKGROUND: Ambulatory and/or home monitoring are recommended in the UK and the US for the diagnosis of hypertension but little is known about their acceptability. AIM: To determine the acceptability of different methods of...
Blood Pressure Monitoring Ethnicity Hypertension patient satisfaction PRIMARY CARE Ambulatory Care Facilities Antihypertensive Agents blood pressure Blood Pressure Monitoring Ambulatory Cross-Sectional Studies England Ethnicity Female Focus Groups Humans Hypertension Male Middle Aged Patient Acceptance of Health Care Patient Care Management Primary Health Care
Determinants of transgender job satisfaction
The purpose of this study is to establish as well as examine the validity and reliability of the instrument to measure the perception of working transgender job satisfaction. The instrument was adopted and adapted from the...
Published by: Department of History, University of Karachi
Measurement of blood pressure for the diagnosis and management of hypertension in different ethnic groups
Paramjit Gill, M Sayeed Haque, Una Martin, Jonathan Mant, Mohammed A Mohammed, Gurdip Heer, Amanpreet Johal, Ramandeep Kaur, Claire Schwartz, Sally Wood, Sheila M Greenfield, Richard J McManus
Feb 09, 2017
BACKGROUND: Hypertension is a major risk factor for cardiovascular disease and prevalence varies by ethnic group. The diagnosis and management of blood pressure are informed by guidelines largely based on data from white...
Local mixture models of exponential families
Exponential families are the workhorses of parametric modelling theory. One reason for their popularity is their associated inference theory, which is very clean, both from a theoretical and a computational point of view. One...
Removing physiological motion from intravital and clinical functional imaging data.
Sean C Warren, Max Nobis, Astrid Magenau, Yousuf H Mohammed, David Herrmann, Imogen Moran, Claire Vennin, James RW Conway, Pauline Mélénec, Thomas R Cox, Yingxiao Wang, Jennifer P Morton, Heidi CE Welch, Douglas Strathdee, Kurt I Anderson, Tri Giang Phan, Michael S Roberts, Paul Timpson
Jun 27, 2019
Intravital microscopy can provide unique insights into the function of biological processes in a native context. However, physiological motion caused by peristalsis, respiration and the heartbeat can present a significant...
FLIM FRET Cell Biology Computational Biology human Intravital Microscopy motion correction MOUSE multiphoton Systems Biology Algorithms Animals Biosensing Techniques Cell Adhesion Computer Simulation Fluorescence Resonance Energy Transfer Guanosine Triphosphate Humans Imaging Three-Dimensional Intestines Intravital Microscopy Mice Microscopy Fluorescence Models Biological Motion Neoplasm Metastasis Neuropeptides Pancreatic Neoplasms Skin Software rac1 GTP-Binding Protein src-Family Kinases
Ethnicity and differences between clinic and ambulatory blood pressure measurements.
Una Martin, M Sayeed Haque, Sally Wood, Sheila M Greenfield, Paramjit S Gill, Jonathan Mant, Mohammed A Mohammed, Gurdip Heer, Amanpreet Johal, Ramendeep Kaur, Claire Schwartz, Richard J McManus
Mar 18, 2015
ambulatory blood pressure monitoring blood pressure Blood Pressure Determination ethnic group Hypertension systolic pressure white coat hypertension. Adult Aged Ambulatory Care Facilities Antihypertensive Agents blood pressure Blood Pressure Monitoring Ambulatory Ethnicity Female Humans Hypertension Male Middle Aged Patient Care Management Practice Patterns Physicians' United Kingdom
Infrapatellar fat pad adipose-derived stem cells co-cultured with articular chondrocytes from osteoarthritis patients exhibit increased chondrogenic gene expression.
AIM: The variable results in clinical trials of adipose tissue-derived stem cells (ASCs) for chondral defects may be due to the different ex vivo culture conditions of the ASCs which are implanted to treat the lesions. We sought...
Anticlockwise or clockwise?
Reviewing the relevant literature in visual psychophysics and visual neuroscience we propose a three-stage model of directionality bias in visuospatial functioning. We call this model the 'Perception-Action-Laterality' (PAL)...
Anticlockwise or clockwise?
Reviewing the relevant literature in visual psychophysics and visual neuroscience we propose a three-stage model of directionality bias in visuospatial functioning. We call this model the 'Perception-Action-Laterality' (PAL)...
Orthogonal simple component analysis
Combining principles with pragmatism, a new approach and accompanying algorithm are presented to a longstanding problem in applied statistics: the interpretation of principal components. Following Rousson and Gasser "the...
Automated Glucose Control
Automated blood glucose control for diabetes mellitus is a highly desired pursuit of researchers around the globe. Advancement in sensing and control capabilities has paced the development of closed-loop control systems for...
Published by: IGI Global Scientific Publishing
Local mixture models of exponential families
Exponential families are the workhorses of parametric modelling theory. One reason for their popularity is their associated inference theory, which is very clean, both from a theoretical and a computational point of view. One...
Managing the surge in demand for blood following mass casualty events. Early automatic restocking may preserve red cell supply
Background: Traumatic hemorrhage is a leading preventable cause of mortality following mass casualty events (MCEs). Improving outcomes requires adequate in-hospital provision of high volume red blood cell (RBC) transfusions....
Managing the surge in demand for blood following mass casualty events. Early automatic restocking may preserve red cell supply
Background: Traumatic hemorrhage is a leading preventable cause of mortality following mass casualty events (MCEs). Improving outcomes requires adequate in-hospital provision of high volume red blood cell (RBC) transfusions....
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