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Results: 19855
Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication.
Iosifina P Foskolou, Christian Jorgensen, Katarzyna B Leszczynska, Monica M Olcina, Hanna Tarhonskaya, Bauke Haisma, Vincenzo D'Angiolella, William K Myers, Carmen Domene, Emily Flashman, Ester M Hammond
May 11, 2020
Cells exposed to hypoxia experience replication stress but do not accumulate DNA damage, suggesting sustained DNA replication. Ribonucleotide reductase (RNR) is the only enzyme capable of de novo synthesis of deoxyribonucleotide...
DNA damage response p53 RNR RRM2B Hypoxia Nucleotides radiosensitivity replication stress Animals Apoptosis Cell Cycle Proteins Colonic Neoplasms DNA Damage DNA Replication DNA Neoplasm Female HCT116 Cells Humans Mice Inbred BALB C Mice Nude Oxygen RNA Interference Radiation Tolerance Ribonucleoside Diphosphate Reductase Ribonucleotide Reductases Time Factors Transfection Tumor Burden Tumor Hypoxia Tumor Suppressor Proteins Xenograft Model Antitumor Assays
Interview with Johann M. McCrackin
Johann M. McCrackin
Jan 01, 0001
Interview with Johann M. McCrackin, 1984 South Carolina Mother of the Year.
Published by: Winthrop University
Polymorphism in M(H2PO2)3 (M = V, Al, Ga) compounds with the perovskite-related ReO3 structure.
Hayden A Evans, Zeyu Deng, Ines E Collings, Yue Wu, Jessica L Andrews, Kartik Pilar, Joshua M Tuffnell, Guang Wu, John Wang, Siân E Dutton, Paul D Bristowe, Ram Seshadri, Anthony K Cheetham
Feb 18, 2019
Trivalent metal hypophosphites with the general formula M(H2PO2)3 (M = V, Al, Ga) adopt the ReO3 structure, with each compound displaying two structural polymorphs. High-pressure synchrotron X-ray studies reveal a...
Thomas M. Rivers, 1934
The Rockefeller University
Jan 01, 0001
Dr. Thomas M. Rivers. Filterable Viruses with Particular Reference to Psittacosis
Lecture delivered April 19th, 1934
Posted with permission
Published by: The Williams & Wilkins Company
Investigating Students' Intention to Use M-Learning
Mohammed Almulla
Jan 01, 2024
Mobile learning (M-learning) has become a crucial tool for both students and educators. The unified theory of acceptance and use of technology (UTAUT), the technology acceptance model (TAM), and outside factors were all included...
Published by: IGI Global Scientific Publishing
Digital M&A and Firm Innovation
This study empirically examines how digital M&A affects firm innovation using data from Chinese listed companies from 2006 to 2019. The results show that digital M&A promotes firm innovation, and our findings also suggest that...
Published by: IGI Global Scientific Publishing
High voltage sulphate cathodes Li<sub>2</sub>M(SO<sub>4</sub>)<sub>2</sub> (M = Fe, Mn, Co)
The search for high voltage cathodes for lithium-ion batteries has led to recent interest in the monoclinic Li2Fe(SO4)2 material which has a voltage of 3.83 V vs. lithium, the highest recorded for a fluorine-free iron-based...
JEFFREY M. FRIEDMAN
The Rockefeller University
Jan 01, 0001
congratulations to Professor Jeffrey M. Friedman, recipient of the 2010 Albert Lasker Basic Medical Research Award
Published by: The Rockefeller University
Frederick M. Allen, 1916
The Rockefeller University
Jan 01, 0001
Frederick M. Allen, M.D. The Role of Fat in Diabetes.
Delivered November 4th, 1916
Published by: J.B. Lippincott Company
High voltage sulphate cathodes Li<sub>2</sub>M(SO<sub>4</sub>)<sub>2</sub> (M = Fe, Mn, Co)
The search for high voltage cathodes for lithium-ion batteries has led to recent interest in the monoclinic Li2Fe(SO4)2 material which has a voltage of 3.83 V vs. lithium, the highest recorded for a fluorine-free iron-based...
IN MEMORY OF RALPH M. STEINMAN
The Rockefeller University
Jan 01, 0001
A Scientific Symposium in Memory of Ralph M. Steinman
See Steinman, Ralph M.
Published by: The Rockefeller University
Dynamic structure mediates halophilic adaptation of a DNA polymerase from the deep-sea brines of the Red Sea.
Masateru Takahashi, Etsuko Takahashi, Luay I Joudeh, Monica Marini, Gobind Das, Mohamed M Elshenawy, Anastassja Akal, Kosuke Sakashita, Intikhab Alam, Muhammad Tehseen, Mohamed A Sobhy, Ulrich Stingl, Jasmeen S Merzaban, Enzo Di Fabrizio, Samir M Hamdan
Nov 05, 2018
The deep-sea brines of the Red Sea are remote and unexplored environments characterized by high temperatures, anoxic water, and elevated concentrations of salt and heavy metals. This environment provides a rare system to study...
Existence theorems of the fractional Yamabe problem
Let X be an asymptotically hyperbolic manifold and Mits conformal infinity. This paper is devoted to deducing several existence results of the fractional Yamabe problem on M under various geometric assumptions on X and M....
Existence theorems of the fractional Yamabe problem
Let X be an asymptotically hyperbolic manifold and Mits conformal infinity. This paper is devoted to deducing several existence results of the fractional Yamabe problem on M under various geometric assumptions on X and M....
Unexpected Migratory Insertion Reactions of M(alkyl)<sub>2</sub> (M = Zn, Cd) and Diamidocarbenes
The electrophilic character of free diamidocarbenes (DACs) allows them to activate inert bonds in small molecules, such as NH3 and P4. Herein, we report that metal coordinated DACs also exhibit...
Factors Affecting Continuance Intention of M-Government
Thamer Alshammari
Jan 01, 2023
Mobile government (m-government) can potentially provide substantial benefits. Nonetheless, the low level of use has prevented realizing the potential benefits of m-government. As a result, researchers have studied the factors...
Published by: IGI Global Scientific Publishing
Wendell M. Stanley, 1938
The Rockefeller University
Jan 01, 0001
Dr. Wendell M. Stanley. The Isolation and Properties of Tobacco Mosaic and Other Virus Proteins
Lecture delivered March, 17th, 1938
Posted with permission
Published by: The William & Wilkins Company
A non-compactness result on the fractional Yamabe problem in large dimensions
Let (Xn+1,g+)bean(n+ 1)dimensional asymptotically hyperbolic manifold with conformal infinity (Mn,[ˆh]). The fractional Yamabe problem addresses to solve Pγ[g+,ˆh(u)=cun+2γn−2γ,u>0 on M where c ∈ R and Pγ[g+,ˆh] is the...
Exploring environmental supply chain innovation in m&a
Organisations are challenged with executing innovation for sustainable development within the context of their operations and value networks—networks which are increasingly fuelled by mergers and acquisitions (M&As)...
The evolution of the dust temperatures of galaxies in the SFR-<i>M</i> plane up to z sim 2
B. Magnelli, D. Lutz, A. Saintonge, S. Berta, P. Santini, M. Symeonidis, B. Altieri, P. Andreani, H. Aussel, M. Béthermin, J. Bock, A. Bongiovanni, J. Cepa, A. Cimatti, A. Conley, E. Daddi, D. Elbaz, N. M. Förster Schreiber, R. Genzel, R. J. Ivison, E. Le Floc'h, G. Magdis, R. Maiolino, R. Nordon, S. J. Oliver, M. Page, A. Pérez García, A. Poglitsch, P. Popesso, F. Pozzi, L. Riguccini, G. Rodighiero, D. Rosario, I. Roseboom, M. Sanchez-Portal, D. Scott, E. Sturm, L. J. Tacconi, I. Valtchanov, L. Wang, S. Wuyts
Jan 01, 2014
We study the evolution of the dust temperature of galaxies in the SFR− M∗ plane up to z ~ 2 using far-infrared and submillimetre observations from the Herschel Space Observatory taken as part of the PACS Evolutionary Probe (PEP)...
Unexpected Migratory Insertion Reactions of M(alkyl)<sub>2</sub> (M = Zn, Cd) and Diamidocarbenes
The electrophilic character of free diamidocarbenes (DACs) allows them to activate inert bonds in small molecules, such as NH3 and P4. Herein, we report that metal coordinated DACs also exhibit...
A non-compactness result on the fractional Yamabe problem in large dimensions
Let (Xn+1,g+)bean(n+ 1)dimensional asymptotically hyperbolic manifold with conformal infinity (Mn,[ˆh]). The fractional Yamabe problem addresses to solve Pγ[g+,ˆh(u)=cun+2γn−2γ,u>0 on M where c ∈ R and Pγ[g+,ˆh] is the...
Interview with Barbara M. Boulware - OH 779
This interview was conducted by Jackson Martin with Barbarba M. Boulware as part of Project 2020: A Collaborative Oral History. Mrs. Boulware discusses the challenges she faced as an educator during the Civil Rights Era and...
Civil Rights Movement Black women race Education Rock Hill School District Divine 9 Delta Sigma Theta law
Published by: Winthrop University
How Do We Construct a Child-Friendly Emergency Management Framework?
Monica Sanders
Jan 01, 2022
When considering vulnerable populations, or those with the most cascading obstacles that cause them to be susceptible to certain hazards and events, children are among the most vulnerable. Those living in poverty or in...
Published by: IGI Global Scientific Publishing
The evolution of the dust temperatures of galaxies in the SFR-<i>M</i> plane up to z sim 2
B. Magnelli, D. Lutz, A. Saintonge, S. Berta, P. Santini, M. Symeonidis, B. Altieri, P. Andreani, H. Aussel, M. Béthermin, J. Bock, A. Bongiovanni, J. Cepa, A. Cimatti, A. Conley, E. Daddi, D. Elbaz, N. M. Förster Schreiber, R. Genzel, R. J. Ivison, E. Le Floc'h, G. Magdis, R. Maiolino, R. Nordon, S. J. Oliver, M. Page, A. Pérez García, A. Poglitsch, P. Popesso, F. Pozzi, L. Riguccini, G. Rodighiero, D. Rosario, I. Roseboom, M. Sanchez-Portal, D. Scott, E. Sturm, L. J. Tacconi, I. Valtchanov, L. Wang, S. Wuyts
Jan 01, 2014
We study the evolution of the dust temperature of galaxies in the SFR− M∗ plane up to z ~ 2 using far-infrared and submillimetre observations from the Herschel Space Observatory taken as part of the PACS Evolutionary Probe (PEP)...
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