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Size Reduction in Early European Domestic Cattle Relates to Intensification of Neolithic Herding Strategies.
Our analysis of over 28,000 osteometric measurements from fossil remains dating between c. 5600 and 1500 BCE reveals a substantial reduction in body mass of 33% in Neolithic central European domestic cattle. We investigate...
Retromer and the cation-independent mannose 6-phosphate receptor-Time for a trial separation?
Matthew NJ Seaman
Feb 02, 2018
The retromer cargo-selective complex (CSC) comprising Vps35, Vps29 and Vps26 mediates the endosome-to-Golgi retrieval of the cation-independent mannose 6-phosphate receptor (CIMPR). Or does it? Recently published data have...
Hydrogel as a Medium for Fluid-Driven Fracture Study
In this paper we describe how to construct polyacrylamide hydrogels to study the processes linked with hydraulic fracturing. These transparent, linearly elastic and brittle gels permit fracturing at low pressures and speeds...
Efficient diode-pumped mid-infrared emission from acetylene-filled hollow-core fiber
We report 3.1-3.2 μm mid-infrared emission from acetylene-filled low loss antiresonant hollow-core fiber pumped with an amplified, modulated, narrowband, tunable 1.5 μm diode laser. The maximum power conversion efficiency of...
Radiofrequency properties of two different Licox® parenchymal brain tissue oxygen probe designs.
Ari Ercole
May 29, 2018
Neuroimaging and continuous multimodality neuromonitoring are both central to the intensive care management of patients with severe traumatic brain injury. Guidelines recommend the use of multimodality monitors including brain...
Using epidemiological principles to explain fungicide resistance management tactics
Whether fungicide resistance management is optimised by spraying chemicals with different modes of action as a mixture (i.e. simultaneously) or in alternation (i.e. sequentially) has been studied by experimenters and modellers...
Large-Scale Tectonic Forcing of the African Landscape
Abstract: Successful inverse modeling of observed longitudinal river profiles suggests that fluvial landscapes are responsive to continent‐wide tectonic forcing. However, inversion algorithms make simplifying assumptions about...
Navigating the Controversies of Retromer-Mediated Endosomal Protein Sorting.
The retromer complex was first identified more than 20 years ago through studies conducted in the yeast Saccharomyces cerevisiae. Data obtained using many different model systems have revealed that retromer is a key component of...
Evaluation of secondary spontaneous pneumothorax with multidetector CT.
The purpose of this article is to review the underlying causes of secondary pneumothoraces as observed on multidetector computed tomography (MDCT). Using examples from our institutional experience, we shall illustrate important...
Vertical Mixing and Heat Fluxes Conditioned by a Seismically Imaged Oceanic Front
The southwest Atlantic gyre connects several distinct water masses, which means that this oceanic region is characterized by a complex frontal system and enhanced water mass modification. Despite its significance, the...
Tm-doped fiber laser mode-locked by graphene-polymer composite.
M Zhang, EJR Kelleher, F Torrisi, Z Sun, T Hasan, D Popa, F Wang, AC Ferrari, SV Popov, JR Taylor
Sep 08, 2018
We demonstrate mode-locking of a thulium-doped fiber laser operating at 1.94 μm, using a graphene-polymer based saturable absorber. The laser outputs 3.6 ps pulses, with ~0.4 nJ energy and an amplitude fluctuation ~0.5%, at 6.46...
A new species of early Cambrian arthropod reconstructed from exceptionally preserved mandibles and associated small carbonaceous fossils (SCFs)
Abstract: Mandibulate arthropods (myriapods, hexapods and crustaceans) account for a major component of extant animal diversity but their origins remain unclear. Here, we re‐examine the record of exceptionally preserved...
The Retromer Complex
Matthew NJ Seaman
Jan 12, 2021
The retromer complex has a well-established role in endosomal protein sorting, being necessary for maintaining the dynamic localisation of hundreds of membrane proteins that traverse the endocytic system. Retromer function and...
The Clinical and Public Health Challenges of Diabetes Prevention
In an Editorial accompanying PLOS Medicine's Special Issue on Diabetes Prevention, Guest Editors Nicholas Wareham and William Herman discuss some of the challenges for researchers and policy makers in developing effective and...
Retromer and Its Role in Regulating Signaling at Endosomes.
Matthew NJ Seaman
Feb 11, 2019
The retromer complex is a key element of the endosomal protein sorting machinery being involved in trafficking of proteins from endosomes to the Golgi and also endosomes to the cell surface. There is now accumulating evidence...
The Grizzly, April 3, 2003
Anne Antanavage, '04, Kelly Gray, Quinn Dinsmore, Bart Brooks, Cassie Stewart, Tia Larese, Lindsey Fund, Fallon Szarko, Joe Calhoun, Jerel Smith, Terri Wehnert, Eric Fierro
Jan 01, 0001
Holy War, Inc.: An Inside Look at Terrorism Networks Ursinus "Wired" Since 1946 How Safe are Ursinus Students: Interview with Mike Ditty Students Sing Praise of the Talent Show Meistersingers Strike a Chord with Audience ...
Ursinus College Collegeville Pennsylvania newspaper baseball gymnastics lacrosse track team Norman David Meistersingers Airband talent show community service Phi Kappa Sigma student government campus safety Mike Ditty Peter Bergen John Mauchly ENIAC cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Perturbation theory for graphene-integrated waveguides
We present perturbation theory for analysis of generic third-order nonlinear processes in graphene-integrated photonic structures. The optical response of graphene is treated as the nonlinear boundary condition in Maxwell's...
Morphogenesis of extra-embryonic tissues directs the remodelling of the mouse embryo at implantation
Neophytos Christodoulou, Antonia Weberling, Douglas Strathdee, Kurt I. Anderson, Paul Timpson, Magdalena Zernicka-Goetz
Aug 06, 2020
Abstract: Mammalian embryos change shape dramatically upon implantation. The cellular and molecular mechanism underlying this transition are largely unknown. Here, we show that this transition is directed by cross talk between...
Obesity and Multiple Sclerosis
Lauren E Mokry, Stephanie Ross, Nicholas J Timpson, Stephen Sawcer, George Davey Smith, J Brent Richards
Jun 15, 2016
BMI as a Modifiable Risk Factor for Type 2 Diabetes
Laura J Corbin, Rebecca C Richmond, Kaitlin H Wade, Stephen Burgess, Jack Bowden, George Davey Smith, Nicholas J Timpson
Aug 17, 2016
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