Search
Results: 201
A field study of indoor thermal comfort in the subtropical highland climate of Bogota, Colombia
This paper undertakes the first field study of indoor thermal comfort in Colombia. The objective of this study was to compare thermal comfort data gathered in office buildings in Bogota, Colombia with the predictions made by...
A field study of indoor thermal comfort in the subtropical highland climate of Bogota, Colombia
This paper undertakes the first field study of indoor thermal comfort in Colombia. The objective of this study was to compare thermal comfort data gathered in office buildings in Bogota, Colombia with the predictions made by...
GTPase-activating protein Rasal1 associates with ZAP-70 of the TCR and negatively regulates T-cell tumor immunity.
Immunotherapy involving checkpoint blockades of inhibitory co-receptors is effective in combating cancer. Despite this, the full range of mediators that inhibit T-cell activation and influence anti-tumor immunity is unclear....
Animals CD4-Positive T-Lymphocytes Extracellular Signal-Regulated MAP Kinases Female GTPase-Activating Proteins Lymphocyte Activation Male Melanoma Experimental Mice Inbred BALB C Mice Inbred C57BL Mice Transgenic Protein Domains RNA Small Interfering Receptors Antigen T-Cell T-Lymphocytes ZAP-70 Protein-Tyrosine Kinase
Reference Genes for Expression Studies in Human CD8 + Naïve and Effector Memory T Cells under Resting and Activating Conditions
Marco Geigges, Patrick M. Gubser, Gunhild Unterstab, Yannic Lecoultre, Renato Paro, Christoph Hess
Jun 10, 2021
Abstract: Reverse-transcription quantitative real-time polymerase chain reaction (RT-qPCR) is widely used for mRNA quantification. To accurately measure changing gene transcript levels under different experimental conditions...
Reference Genes for Expression Studies in Human CD8+ Naïve and Effector Memory T Cells under Resting and Activating Conditions.
Marco Geigges, Patrick M Gubser, Gunhild Unterstab, Yannic Lecoultre, Renato Paro, Christoph Hess
Jun 22, 2020
Reverse-transcription quantitative real-time polymerase chain reaction (RT-qPCR) is widely used for mRNA quantification. To accurately measure changing gene transcript levels under different experimental conditions, the use of...
Nitrous oxide emissions from sugarcane fields in the Brazilian Cerrado
J Fonseca da Silva, A Moreira de Carvalho, TA Rein, T Rodrigues Coser, W Quadros Ribeiro, D Lino Vieira, DA Coomes
Nov 24, 2017
Brazil meets about 16% of its energy needs with bioethanol and other sugarcane products and leads the world in biofuel energy production. However, there are concerns over the environmental credentials of the sugarcane given the...
Immune adaptor SKAP1 acts a scaffold for Polo-like kinase 1 (PLK1) for the optimal cell cycling of T-cells.
While the immune cell adaptor protein SKAP1 mediates LFA-1 activation induced by antigen-receptor (TCR/CD3) ligation on T-cells, it is unclear whether the adaptor interacts with other mediators of T-cell function. In this...
“Mind reading” building operation behaviour
Modern buildings are operationally classified as fully naturally ventilated (free running, FR), fully mechanically ventilated and conditioned (air-conditioned, AC) or intermediary (mixed mode, MM). Each strategy implies (i)...
“Mind reading” building operation behaviour
Modern buildings are operationally classified as fully naturally ventilated (free running, FR), fully mechanically ventilated and conditioned (air-conditioned, AC) or intermediary (mixed mode, MM). Each strategy implies (i)...
Autism and the right to education in the EU
Monika Roleska, Andres Roman-Urrestarazu, Sarah Griffiths, Amber NV Ruigrok, Rosemary Holt, Robin van Kessel, Kathleen McColl, William Sherlaw, Carol Brayne, Kasia Czabanowska
Dec 17, 2018
INTRODUCTION: Autistic people may have different educational needs that need to be met to allow them to develop their full potential. Education and disability policies remain within the competence of EU Member States, with...
Activated Cdc42-associated kinase 1 (ACK1) binds the sterile α motif (SAM) domain of the adaptor SLP-76 and phosphorylates proximal tyrosines
T cell Cell Signaling cluster of differentiation 4 (CD4) immunology non-receptor tyrosine kinase (nRTK) protein phosphorylation sterile α motif (SAM) Adaptor Proteins Signal Transducing Amino Acid Motifs Amino Acid Substitution Animals Humans Jurkat Cells Lymphocyte Activation Mice Mutation Missense Phosphoproteins Phosphorylation Protein Domains Protein-Tyrosine Kinases Receptors Antigen T-Cell T-Lymphocytes Tyrosine
Positron Emission Tomography and Magnetic Resonance Imaging of Cellular Inflammation in Patients with Abdominal Aortic Aneurysms.
OMB McBride, NV Joshi, JMJ Robson, TJ MacGillivray, CD Gray, AM Fletcher, MR Dweck, EJR van Beek, JHF Rudd, DE Newby, SI Semple
Apr 20, 2016
Abdominal aortic aneurysms Computed tomography Magnetic Resonance Imaging positron emission tomography Aged Aorta Abdominal Aortic Aneurysm Abdominal Aortitis Aortography Contrast Media Dextrans Female Fluorodeoxyglucose F18 Glycolysis Humans MACROPHAGES Magnetic Resonance Imaging Magnetite Nanoparticles Male Multimodal Imaging Phagocytosis Positron-Emission Tomography Predictive Value of Tests Radiopharmaceuticals Tomography X-Ray Computed
Maternal age, autistic-like traits and mentalizing as predictors of child autistic-like traits in a population-based cohort.
Novika Purnama Sari, Pauline W Jansen, Laura ME Blanken, Amber NV Ruigrok, Peter Prinzie, Henning Tiemeier, Simon Baron-Cohen, Marinus H van IJzendoorn, Tonya White
Jul 16, 2022
BACKGROUND: Many empirical studies suggest that higher maternal age increases the likelihood of having an autistic child. However, little is known about factors that may explain this relationship or if higher maternal age is...
Maternal age, autistic-like traits and mentalizing as predictors of child autistic-like traits in a population-based cohort.
A meta-analysis of sex differences in human brain structure.
Amber NV Ruigrok, Gholamreza Salimi-Khorshidi, Meng-Chuan Lai, Simon Baron-Cohen, Michael V Lombardo, Roger J Tait, John Suckling
Aug 08, 2017
The prevalence, age of onset, and symptomatology of many neuropsychiatric conditions differ between males and females. To understand the causes and consequences of sex differences it is important to establish where they occur in...
Enhancement of indirect functional connections with shortest path length in the adult autistic brain.
Xiaonan Guo, Tiago Simas, Meng-Chuan Lai, Michael V Lombardo, Bhismadev Chakrabarti, Amber NV Ruigrok, Edward T Bullmore, Simon Baron-Cohen, Huafu Chen, John Suckling, MRC AIMS Consortium
Sep 16, 2019
Autism is a neurodevelopmental condition characterized by atypical brain functional organization. Here we investigated the intrinsic indirect (semi-metric) connectivity of the functional connectome associated with autism....
Neural self-representation in autistic women and association with 'compensatory camouflaging'.
Meng-Chuan Lai, Michael V Lombardo, Bhismadev Chakrabarti, Amber NV Ruigrok, Edward T Bullmore, John Suckling, Bonnie Auyeung, Francesca Happé, Peter Szatmari, Simon Baron-Cohen, MRC AIMS Consortium
Dec 03, 2018
Prior work has revealed sex/gender-dependent autistic characteristics across behavioural and neural/biological domains. It remains unclear whether and how neural sex/gender differences are related to behavioural sex/gender...
Adult autism camouflaging compensation functional magnetic resonance imaging Gender Heterogeneity Mentalizing Self sex Adolescent Adult Autistic Disorder Brain Case-Control Studies Female Functional Neuroimaging Humans Magnetic Resonance Imaging Male mentalization Middle Aged Self Concept Sex Factors Social Behavior Young Adult
Current Status of Cell-Based Therapies for Vitiligo.
Anna Domaszewska-Szostek, Agnieszka Polak, Monika Słupecka-Ziemilska, Marta Krzyżanowska, Monika Puzianowska-Kuźnicka
Mar 28, 2023
Vitiligo is a chronic pigmentary disease with complex etiology, the signs of which are caused by the destruction of melanocytes in the epidermis, leading to the lack of melanin pigment responsible for skin coloration. The...
Keratinocytes Melanocytes Cell transplantation vitiligo melanogenesis cell-based therapies epidermis Humans Hypopigmentation Treatment Outcome
Published by: International journal of molecular sciences
Improving effect size estimation and statistical power with multi-echo fMRI and its impact on understanding the neural systems supporting mentalizing.
Concentration and origin of lead (Pb) in liver and bone of Eurasian buzzards (Buteo buteo) in the United Kingdom.
Mark A Taggart, Richard F Shore, Deborah J Pain, Gabriela Peniche, Mónica Martinez-Haro, Rafael Mateo, Julia Homann, Andrea Raab, Joerg Feldmann, Alan J Lawlor, Elaine D Potter, Lee A Walker, David W Braidwood, Andrew S French, Jemima Parry-Jones, John A Swift, Rhys E Green
Sep 10, 2020
Ingestion of lead (Pb) derived from ammunition used in the hunting of game animals is recognised to be a significant potential source of Pb exposure of wild birds, including birds of prey. However, there are only limited data...
In Vivo Evidence of Reduced Integrity of the Gray-White Matter Boundary in Autism Spectrum Disorder.
Derek Sayre Andrews, Thomas A Avino, Maria Gudbrandsen, Eileen Daly, Andre Marquand, Clodagh M Murphy, Meng-Chuan Lai, Michael V Lombardo, Amber NV Ruigrok, Steven C Williams, Edward T Bullmore, The Mrc Aims Consortium, John Suckling, Simon Baron-Cohen, Michael C Craig, Declan GM Murphy, Christine Ecker
Aug 17, 2017
Atypical cortical organization and reduced integrity of the gray-white matter boundary have been reported by postmortem studies in individuals with autism spectrum disorder (ASD). However, there are no in vivo studies that...
|
|< |
< |
1 |