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Rough Music and Charivari
Alexandra Walsham
Oct 31, 2018
In 1971 Natalie Zemon Davis published a seminal article in the pages of Past and Present, entitled ‘The Reasons of Misrule: Youth Groups and Charivaris in Sixteenth-Century France’. A study of the carnivalesque rituals of...
Winthrop Student's Photograph Chosen for National Publication
Winthrop University
Jan 01, 0001
Winthrop freshman considered a finalist in the 29th Annual College Photography contest. Natalie Gann's photograph was taken in the yard of a historical museum in Georgetown, S.C.
Published by: Winthrop University
Open questions
Judy Hirst
Sep 11, 2019
The Grizzly, November 16, 2023
Marie Sykes, Sidney Belleroche, Isabel Martinez-Robles, Erin Corcoran, Zachary Hassett, Andrew J. Perez, Charlotte DiLello, Dominic Minicozzi
Jan 01, 0001
Fantastic Strings Ensemble Crossword Celebration of Lights (In Photos) A Conversation With Ursinus' Archivist, Carolyn Weigel Food Forest Continues to Grow The Creative Collegeville Italian Bakery From Opponent to Family...
Ursinus College Collegeville Pennsylvania newspaper Ursinus Strings Ensemble Celebration of Lights Ursinusiana Carolyn Weigel food forest Lenape Collegeville Italian Bakery Natalie Mehl Football cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Comment on "Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry".
Chorev et al (Reports, 16 November 2018, p. 829) describe mass spectrometry on mitochondrial membrane proteins ionized directly from their native environment. However, the assignments made to measured masses are incorrect or...
Paracoccus denitrificans
Mitochondrial complex I (NADH:ubiquinone oxidoreductase) is a crucial metabolic enzyme that couples the free energy released from NADH oxidation and ubiquinone reduction to the translocation of four protons across the inner...
Published by: Scientific reports
Performance Information Artifacts
The field of performance management is premised on the centrality of measurement and performance information use in everyday decision making and practice. Information is managed through the use of information systems, but...
Published by: IGI Global Scientific Publishing
Structure of mammalian respiratory complex I.
Complex I (NADH:ubiquinone oxidoreductase), one of the largest membrane-bound enzymes in the cell, powers ATP synthesis in mammalian mitochondria by using the reducing potential of NADH to drive protons across the inner...
Mitochondrial Supercomplexes Do Not Enhance Catalysis by Quinone Channeling.
Mitochondrial respiratory supercomplexes, comprising complexes I, III, and IV, are the minimal functional units of the electron transport chain. Assembling the individual complexes into supercomplexes may stabilize them, provide...
alternative oxidase channeling Mitochondria Oxidative Phosphorylation respirasome supercomplex Ubiquinone Animals Benzoquinones Biocatalysis Cattle Cell Respiration Electron Transport Complex I Electron Transport Complex III Electron Transport Complex IV Female Kinetics Male Mitochondria Heart Mitochondrial Membranes Oxidation-Reduction Oxidative Phosphorylation Oxidoreductases
Membrane-domain mutations in respiratory complex I impede catalysis but do not uncouple proton pumping from ubiquinone reduction.
Respiratory complex I [NADH:ubiquinone (UQ) oxidoreductase] captures the free energy released from NADH oxidation and UQ reduction to pump four protons across an energy-transducing membrane and power ATP synthesis. Mechanisms...
Mammalian Respiratory Complex I Through the Lens of Cryo-EM.
Single-particle electron cryomicroscopy (cryo-EM) has led to a revolution in structural work on mammalian respiratory complex I. Complex I (mitochondrial NADH:ubiquinone oxidoreductase), a membrane-bound redox-driven proton...
Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation.
Mitochondrial complex I powers ATP synthesis by oxidative phosphorylation, exploiting the energy from ubiquinone reduction by NADH to drive protons across the energy-transducing inner membrane. Recent cryo-EM analyses of...
Using a chimeric respiratory chain and EPR spectroscopy to determine the origin of semiquinone species previously assigned to mitochondrial complex I
Abstract: Background: For decades, semiquinone intermediates have been suggested to play an essential role in catalysis by one of the most enigmatic proton-pumping enzymes, respiratory complex I, and different mechanisms have...
Using a chimeric respiratory chain and EPR spectroscopy to determine the origin of semiquinone species previously assigned to mitochondrial complex I
Abstract: Background: For decades, semiquinone intermediates have been suggested to play an essential role in catalysis by one of the most enigmatic proton-pumping enzymes, respiratory complex I, and different mechanisms have...
Respiratory Complex I in Bos taurus and Paracoccus denitrificans Pumps Four Protons across the Membrane for Every NADH Oxidized.
Respiratory complex I couples electron transfer between NADH and ubiquinone to proton translocation across an energy-transducing membrane to support the proton-motive force that drives ATP synthesis. The proton-pumping...
Complex I electron transfer complex Mitochondria mitochondrial respiratory chain complex Oxidative Phosphorylation proton motive force Adenosine Triphosphate Animals Cattle Electron Transport Electron Transport Complex I Mitochondria NAD Oxidation-Reduction Oxidative Phosphorylation Paracoccus denitrificans Proton-Motive Force Protons
Rag GTPases and phosphatidylinositol 3-phosphate mediate recruitment of the AP-5/SPG11/SPG15 complex.
Adaptor protein complex 5 (AP-5) and its partners, SPG11 and SPG15, are recruited onto late endosomes and lysosomes. Here we show that recruitment of AP-5/SPG11/SPG15 is enhanced in starved cells and occurs by coincidence...
Adaptor Proteins Vesicular Transport Carrier Proteins Endosomes HEK293 Cells HeLa Cells Humans Lysosomes Mechanistic Target of Rapamycin Complex 1 Models Biological Monomeric GTP-Binding Proteins Multiprotein Complexes Nucleotides Phosphatidylinositol 3-Kinases Phosphatidylinositol Phosphates Protein Domains Proteins
Transparent Quasi-Random Structures for Multimodal Light Trapping in Ultrathin Solar Cells with Broad Engineering Tolerance.
Waveguide modes are well-known to be a valuable light-trapping resource for absorption enhancement in solar cells. However, their scarcity in the thinnest device stacks compromises the multiresonant performance required to reach...
Molecular features of biguanides required for targeting of mitochondrial respiratory complex I and activation of AMP-kinase.
BACKGROUND: The biguanides are a family of drugs with diverse clinical applications. Metformin, a widely used anti-hyperglycemic biguanide, suppresses mitochondrial respiration by inhibiting respiratory complex I. Phenformin, a...
AMP kinase Biguanide Metformin NADH:ubiquinone oxidoreductase Respiratory complex I Adenylate Kinase Animals Biguanides Cattle Cell Line Tumor Cell Membrane Permeability Cell Respiration Electron Transport Complex I Enzyme Activation Mice Mitochondria Mitochondrial Membranes Oxygen Consumption Phenformin Rats Rotenone Solubility
Complexome profile of Toxoplasma gondii mitochondria identifies divergent subunits of respiratory chain complexes including new subunits of cytochrome bc1 complex.
Andrew E Maclean, Hannah R Bridges, Mariana F Silva, ShuJing Ding, Jana Ovciarikova, Judy Hirst, Lilach Sheiner
Mar 23, 2021
The mitochondrial electron transport chain (mETC) and F1Fo-ATP synthase are of central importance for energy and metabolism in eukaryotic cells. The Apicomplexa, important pathogens of humans causing diseases such as...
Paracoccus denitrificans
Abstract: Mitochondrial complex I (NADH:ubiquinone oxidoreductase) is a crucial metabolic enzyme that couples the free energy released from NADH oxidation and ubiquinone reduction to the translocation of four protons across the...
If S/He Be Worthy
This study examined Redditors' reactions to the announcement that Natalie Portman will play female Thor in Thor: Love and Thunder. The discussions on Reddit allowed fans to voice support, trepidation, and condemnation of the...
Civic Engagement & Social Justice Social Sciences and Humanities Gender and Diversity Government and Law
Published by: IGI Global Scientific Publishing
Using a chimeric respiratory chain and EPR spectroscopy to determine the origin of semiquinone species previously assigned to mitochondrial complex I.
BACKGROUND: For decades, semiquinone intermediates have been suggested to play an essential role in catalysis by one of the most enigmatic proton-pumping enzymes, respiratory complex I, and different mechanisms have been...
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