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Results: 491
Murine Kupffer cells: mononuclear phagocytes deficient in the generation of reactive oxygen intermediates
Lepay, D.A., Nathan, C.F., Steinman, R.M., Murray, H.W., and Cohn, Z.A. Murine Kupffer cells: mononuclear phagocytes deficient in the generation of reactive oxygen intermediates. J. Exp. Med. 161: 1079-1096, 1985
Published by: The Rockefeller University Press
Distinct pathogenic roles for resident and monocyte-derived macrophages in lupus nephritis.
Nathan Richoz, Zewen K Tuong, Kevin W Loudon, Eduardo Patiño-Martínez, John R Ferdinand, Anaïs Portet, Kathleen R Bashant, Emeline Thevenon, Francesca Rucci, Thomas Hoyler, Tobias Junt, Mariana J Kaplan, Richard M Siegel, Menna R Clatworthy
Dec 09, 2022
The impact of hypoxia on B cells in COVID-19.
Prasanti Kotagiri, Federica Mescia, Aimee L Hanson, Lorinda Turner, Laura Bergamaschi, Ana Peñalver, Nathan Richoz, Stephen D Moore, Brian M Ortmann, Benjamin J Dunmore, Michael D Morgan, Zewen Kelvin Tuong, Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration, Berthold Göttgens, Mark Toshner, Christoph Hess, Patrick H Maxwell, Menna R Clatworthy, James A Nathan, John R Bradley, Paul A Lyons, Natalie Burrows, Kenneth GC Smith
Mar 28, 2022
Archives Moving From Dacus Library and Will Reopen on Jan. 2
Winthrop University
Jan 01, 0001
Researchers, scholars, genealogists and others are expected to flock to the archives to pore over its contents, which number more than six million items. Some of the most popular draws will be the 5,000-year-old cuneiform...
Published by: Winthrop University
SIFE Team Declared as 2012 Charlotte Regional Champions
Winthrop University
Jan 01, 0001
This makes the eighth straight year that Winthrop's team has taken first place at regionals. Team members are Deja Frederick, a senior integrated marketing communication major; Kayla Dugger, a junior digital information design...
Published by: Winthrop University
Ocean acidification and the Permo-Triassic mass extinction.
MO Clarkson, SA Kasemann, RA Wood, TM Lenton, SJ Daines, S Richoz, F Ohnemueller, A Meixner, SW Poulton, ET Tipper
Jun 07, 2019
Ocean acidification triggered by Siberian Trap volcanism was a possible kill mechanism for the Permo-Triassic Boundary mass extinction, but direct evidence for an acidification event is lacking. We present a high-resolution...
Genetic approaches to understand cellular responses to oxygen availability.
Oxygen-sensing mechanisms have evolved to allow organisms to respond and adapt to oxygen availability. In metazoans, oxygen-sensing is predominantly mediated by the hypoxia inducible factors (HIFs). These transcription factors...
Metabolic Regulation of Hypoxia-Inducible Transcription Factors
Hypoxia-inducible transcription factors (HIFs) facilitate cellular adaptations to low-oxygen environments. However, it is increasingly recognised that HIFs may be activated in response to metabolic stimuli, even when oxygen is...
Energy Autonomous Sweat-Based Wearable Systems.
The continuous operation of wearable electronics demands reliable sources of energy, currently met through Li-ion batteries and various energy harvesters. These solutions are being used out of necessity despite potential safety...
Tail state mediated conduction in zinc tin oxide thinfilm phototransistors under below bandgap optical excitation.
We report on the appearance of a strong persistent photoconductivity (PPC) and conductor-like behaviour in zinc tin oxide (ZTO) thinfilm phototransistors. The active ZTO channel layer was prepared by remote plasma reactive...
The Proteasome Distinguishes between Heterotypic and Homotypic Lysine-11-Linked Polyubiquitin Chains.
Guinevere L Grice, Ian T Lobb, Michael P Weekes, Steven P Gygi, Robin Antrobus, James A Nathan
Jul 01, 2015
Murine kupffer cells: Mononuclear phagocytes deficient in the generation of reactive oxygen intermediates
[No abstract available]
Published by: Rockefeller University
Liver macrophages in murine listeriosis: Cell-mediated immunity is correlated with an influx of macrophages capable o f generating reactive oxygen intermediates
[No abstract available]
cellular immunity kupffer cell Listeria monocytogenes listeriosis macrophage reticuloendothelial system
Published by: Rockefeller University
Mono-Type TFT Logic Architectures for Low Power Systems on Panel Applications
This paper introduces novel 7-T pseudo-CMOS for enhancement mode and 6-T pseudo-CMOS for depletion mode inverter circuit architectures. The designs are built around mono-type of TFTs and consume less power consumption than...
Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis.
Chenzhi Jing, Tomas Castro-Dopico, Nathan Richoz, Zewen K Tuong, John R Ferdinand, Laurence SC Lok, Kevin W Loudon, Gemma D Banham, Rebeccah J Mathews, Zaeem Cader, Susan Fitzpatrick, Kathleen R Bashant, Mariana J Kaplan, Arthur Kaser, Randall S Johnson, Michael P Murphy, Richard M Siegel, Menna R Clatworthy
May 20, 2020
IgG antibodies cause inflammation and organ damage in autoimmune diseases such as systemic lupus erythematosus (SLE). We investigated the metabolic profile of macrophages isolated from inflamed tissues in immune complex...
Fcγ receptors Lupus Nephritis metabolism Animals Cells Cultured Cellular Reprogramming Dinoprostone Energy Metabolism Gene Expression Regulation Glycolysis Humans Immunoglobulin G Interleukin-1beta Kidney Lupus Nephritis MACROPHAGES Mice Mice Inbred C57BL Mice Knockout Reactive Oxygen Species Receptors IgG
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