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Results: 94
Interview with Doug Echols
Doug Echols
Jan 01, 0001
In his March 16, 2015 interview with Rebecca Masters, Doug Echols comments on the transitions that took place at Winthrop from 1982- present. In particular, Echols provides detail on the efforts of the DiGiorgio Administration...
Winthrop History Athletics Winthrop Coliseum Presidents DiGiorgio Administration Rock Hill Knowledge Park College Town economic development trolley Jamie Comstock Debra Boyd Oral History
Published by: Winthrop University
Interview with Nathaniel Jaggers - OH 704
This interview was conducted by Dr. George Garrison, an African American studies scholar, with Rock Hill native Nathaniel Jaggers (b.1934). Mr. Jaggers, an Emmett Scott attendee (1940-1951), discusses his experiences and...
Published by: Winthrop University
Sylvia Echols' Tribute Benefits Early Learning Partnership at Winthrop
Winthrop University
Jan 01, 0001
The tribute focused on Echols' lifelong commitment to advocacy for children, especially in York County, where she was a founding member of the Early Learning Partnership of S.C. (formerly Success by 6). Led by Board Chair John...
Published by: Winthrop University
Phaser.MRage
Gábor Bunkóczi, Nathaniel Echols, Airlie J McCoy, Robert D Oeffner, Paul D Adams, Randy J Read
May 11, 2020
Phaser.MRage is a molecular-replacement automation framework that implements a full model-generation workflow and provides several layers of model exploration to the user. It is designed to handle a large number of models and...
phenix.mr_rosetta
Thomas C Terwilliger, Frank Dimaio, Randy J Read, David Baker, Gábor Bunkóczi, Paul D Adams, Ralf W Grosse-Kunstleve, Pavel V Afonine, Nathaniel Echols
May 11, 2020
The combination of algorithms from the structure-modeling field with those of crystallographic structure determination can broaden the range of templates that are useful for structure determination by the method of molecular...
Macromolecular X-ray structure determination using weak, single-wavelength anomalous data.
Gábor Bunkóczi, Airlie J McCoy, Nathaniel Echols, Ralf W Grosse-Kunstleve, Paul D Adams, James M Holton, Randy J Read, Thomas C Terwilliger
May 11, 2020
We describe a likelihood-based method for determining the substructure of anomalously scattering atoms in macromolecular crystals that allows successful structure determination by single-wavelength anomalous diffraction (SAD)...
Automated identification of elemental ions in macromolecular crystal structures.
Nathaniel Echols, Nader Morshed, Pavel V Afonine, Airlie J McCoy, Mitchell D Miller, Randy J Read, Jane S Richardson, Thomas C Terwilliger, Paul D Adams
May 11, 2020
Many macromolecular model-building and refinement programs can automatically place solvent atoms in electron density at moderate-to-high resolution. This process frequently builds water molecules in place of elemental ions, the...
Automating crystallographic structure solution and refinement of protein-ligand complexes.
Nathaniel Echols, Nigel W Moriarty, Herbert E Klei, Pavel V Afonine, Gábor Bunkóczi, Jeffrey J Headd, Airlie J McCoy, Robert D Oeffner, Randy J Read, Thomas C Terwilliger, Paul D Adams
May 11, 2020
High-throughput drug-discovery and mechanistic studies often require the determination of multiple related crystal structures that only differ in the bound ligands, point mutations in the protein sequence and minor...
Commencement Highlights Include Photography Major's Finish and Honorary Degrees
Winthrop University
Jan 01, 0001
Austin Harmon is one of more than 310 students receiving their undergraduate degrees on Saturday at 11 a.m. at the Winthrop Coliseum. President Anthony DiGiorgio also will present honorary degrees to S.C. State Senator Hugh...
Published by: Winthrop University
Graphical tools for macromolecular crystallography in PHENIX.
Nathaniel Echols, Ralf W Grosse-Kunstleve, Pavel V Afonine, Gábor Bunkóczi, Vincent B Chen, Jeffrey J Headd, Airlie J McCoy, Nigel W Moriarty, Randy J Read, David C Richardson, Jane S Richardson, Thomas C Terwilliger, Paul D Adams
May 11, 2020
A new Python-based graphical user interface for the PHENIX suite of crystallography software is described. This interface unifies the command-line programs and their graphical displays, simplifying the development of new...
Winthrop Alumni Named Come-See-Me Festival's 2016 Community Service Award Winners
Winthrop University
Jan 01, 0001
2016 Community Service awards are given to volunteers who demonstrate selfless service and commitment to others. Both Dalton and Echols live in Rock Hill.
Published by: Winthrop University
PHENIX
Paul D Adams, Pavel V Afonine, Gábor Bunkóczi, Vincent B Chen, Ian W Davis, Nathaniel Echols, Jeffrey J Headd, Li-Wei Hung, Gary J Kapral, Ralf W Grosse-Kunstleve, Airlie J McCoy, Nigel W Moriarty, Robert Oeffner, Randy J Read, David C Richardson, Jane S Richardson, Thomas C Terwilliger, Peter H Zwart
Nov 06, 2019
Macromolecular X-ray crystallography is routinely applied to understand biological processes at a molecular level. However, significant time and effort are still required to solve and complete many of these structures because of...
Small Molecule Activation of Yap for Inner-Ear Regeneration and Beyond
Nathaniel Kastan
Jan 01, 0001
Hippo signaling is an evolutionarily conserved pathway that restricts organ growth during development and suppresses regeneration in mature organs. Using a highthroughput phenotypic screen, we have identified a potent...
Published by: Rockefeller University
Local Perspectives on Spatial Accessibility to Market in the Afram Plains, Ghana
The capacity to reach surrounding areas from a location, commonly known as spatial accessibility, is crucial in the economic development of such a location. The Afram Plains in Ghana, despite been touted as the food basket of...
Published by: IGI Global Scientific Publishing
Making Discoveries that Transform Science
The Rockefeller University
Jan 01, 0001
Written and designed by the Office of Communications and Public Affairs for The Rockefeller University, this publication spotlights pathbreaking research of a few of the university's 75 major laboratories: Roderick MacKinnon...
Published by: The Rockefeller University
Rock Hill City Election Candidate Forum Set for Winthrop on Oct. 3
Winthrop University
Jan 01, 0001
The Oct. 3 forum will feature a 6:30 p.m. question and answer time for City Council candidates and a 7 p.m. question and answer time for mayoral candidates. Voters will go to the polls on Oct. 17 to elect a new mayor and members...
Published by: Winthrop University
Small-Molecule Activation of YAP for Inner-Ear Regeneration and Beyond
Nathaniel Kastan
Jan 01, 0001
Hippo signaling is an evolutionarily conserved pathway that restricts organ growth during development and suppresses regeneration in mature organs. Using a highthroughput phenotypic screen, we have identified a potent...
Published by: Rockefeller University
Winthrop Begins Katrina Emergency Relief Response
Winthrop University
Jan 01, 0001
Winthrop University has joined Mayor Doug Echols of Rock Hill who convened concerned community leaders from York County to help coordinate a concentrated effort on behalf of the countless victims of this disaster. The Winthrop...
Published by: Winthrop University
Dignitaries From State, D.C. Praise President DiGiorgio at Tribute
Winthrop University
Jan 01, 0001
DiGiorgio will step down in 2013 after 24 years as president. U.S. Sen. Lindsey Graham, R-S.C., called DiGiorgio the "Strom Thurmond of higher education." Rock Hill Mayor Doug Echols presented DiGiorgio and wife Gale with a key...
Published by: Winthrop University
Focality and Asymmetry in Multi-battle Contests
This article examines the influence of focality in Colonel Blotto games with a lottery contest success function, where the equilibrium is unique and in pure strategies. We hypothesize that the salience of battlefields affects...
Influence of shear-thinning blood rheology on the laminar-turbulent transition over a backward facing step
Cardiovascular diseases are the leading cause of death globally and there is an unmet need for effective, safer blood-contacting devices, including valves, stents and artificial hearts. In these, recirculation regions promote...
Influence of shear-thinning blood rheology on the laminar-turbulent transition over a backward facing step
Cardiovascular diseases are the leading cause of death globally and there is an unmet need for effective, safer blood-contacting devices, including valves, stents and artificial hearts. In these, recirculation regions promote...
Perception and Periodization
Nathaniel Zetter
Mar 23, 2016
This is the final version of the article. It first appeared from Studies in Control Societies via http://studiesincontrolsocieties.org/perception-and-periodization/.
Training flexible conceptual retrieval in post-stroke aphasia.
Sara Stampacchia, Glyn P Hallam, Hannah E Thompson, Upasana Nathaniel, Lucilla Lanzoni, Jonathan Smallwood, Matthew A Lambon Ralph, Elizabeth Jefferies
Mar 08, 2021
Semantic therapy in post-stroke aphasia typically focusses on strengthening links between conceptual representations and their lexical-articulatory forms to aid word retrieval. However, research has shown that semantic deficits...
Prioritized memory access explains planning and hippocampal replay.
To make decisions, animals must evaluate candidate choices by accessing memories of relevant experiences. Yet little is known about which experiences are considered or ignored during deliberation, which ultimately governs...
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