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Results: 29
Can short PROMs support valid factor-based sub-scores? Example of COMQ-12 in chronic otitis media.
PURPOSE: Interpretable factor solutions for questionnaire instruments are typically taken as justification for use of factor-based sub-scores. They can indeed articulate content and construct validities of a total and components...
Can short PROMs support valid factor-based sub-scores? Example of COMQ-12 in chronic otitis media.
PURPOSE: Interpretable factor solutions for questionnaire instruments are typically taken as justification for use of factor-based sub-scores. They can indeed articulate content and construct validities of a total and components...
An Ontology and Semantic Web Service for Quantum Chemistry Calculations.
Nenad Krdzavac, Sebastian Mosbach, Daniel Nurkowski, Philipp Buerger, Jethro Akroyd, Jacob Martin, Angiras Menon, Markus Kraft
Jun 17, 2019
Low- and high-fidelity modeling of sandwich-structured composite response to bird strike, as tools for a digital-twin-assisted damage diagnosis
Efthimis Giannaros, Athanasios Kotzakolios, Vassilis Kostopoulos, George Sotiriadis, Rade Vignjevic, Nenad Djordjevic, Marco Boccaccio, Michele Meo
Feb 28, 2022
The constant requirement of aerospace industry to enhance the structural efficiency has driven to the usage of high-performance composite materials, either monolithic or sandwich. However, aerospace composite structures are...
Bird strike COMPOSITES digital twin FBG sensors FEM-SPH LS-DYNA Sandwich panel Soft body impact /dk/atira/pure/subjectarea/asjc/2200/2205 name=Civil and Structural Engineering /dk/atira/pure/subjectarea/asjc/2200/2203 name=Automotive Engineering /dk/atira/pure/subjectarea/asjc/2200/2202 name=Aerospace Engineering /dk/atira/pure/subjectarea/asjc/2200/2213 name=Safety, Risk, Reliability and Quality /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2200/2211 name=Mechanics of Materials /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering
Multiscale Cross-Domain Thermochemical Knowledge-Graph.
Sebastian Mosbach, Angiras Menon, Feroz Farazi, Nenad Krdzavac, Xiaochi Zhou, Jethro Akroyd, Markus Kraft
Jun 02, 2021
In this paper, we develop a set of software agents which improve a knowledge-graph containing thermodynamic data of chemical species by means of quantum chemical calculations and error-canceling balanced reactions. The...
Low- and high-fidelity modeling of sandwich-structured composite response to bird strike, as tools for a digital-twin-assisted damage diagnosis
Efthimis Giannaros, Athanasios Kotzakolios, Vassilis Kostopoulos, George Sotiriadis, Rade Vignjevic, Nenad Djordjevic, Marco Boccaccio, Michele Meo
Feb 28, 2022
The constant requirement of aerospace industry to enhance the structural efficiency has driven to the usage of high-performance composite materials, either monolithic or sandwich. However, aerospace composite structures are...
Bird strike COMPOSITES digital twin FBG sensors FEM-SPH LS-DYNA Sandwich panel Soft body impact /dk/atira/pure/subjectarea/asjc/2200/2205 name=Civil and Structural Engineering /dk/atira/pure/subjectarea/asjc/2200/2203 name=Automotive Engineering /dk/atira/pure/subjectarea/asjc/2200/2202 name=Aerospace Engineering /dk/atira/pure/subjectarea/asjc/2200/2213 name=Safety, Risk, Reliability and Quality /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2200/2211 name=Mechanics of Materials /dk/atira/pure/subjectarea/asjc/2200/2210 name=Mechanical Engineering
BMI-related cortical morphometry changes are associated with altered white matter structure.
Nenad Medic, Peter Kochunov, Hisham Ziauddeen, Karen D Ersche, Pradeep J Nathan, Lisa Ronan, Paul C Fletcher
Jan 07, 2019
Dopamine modulates the neural representation of subjective value of food in hungry subjects.
Nenad Medic, Hisham Ziauddeen, Martin D Vestergaard, Elana Henning, Wolfram Schultz, I Sadaf Farooqi, Paul C Fletcher
Aug 14, 2014
MiR-221 influences effector functions and actin cytoskeleton in mast cells.
Ramon J Mayoral, Lorenzo Deho, Nicole Rusca, Nenad Bartonicek, Harpreet Kaur Saini, Anton J Enright, Silvia Monticelli
Jan 23, 2018
Mast cells have essential effector and immunoregulatory functions in IgE-associated allergic disorders and certain innate and adaptive immune responses, but the role of miRNAs in regulating mast cell functions is almost...
3T3 Cells Actin Cytoskeleton Actins Animals Base Sequence Bone Marrow Cells Cell Adhesion Cell Degranulation Cell Differentiation Cell Movement Cell Proliferation Cyclin-Dependent Kinase Inhibitor p27 Down-Regulation FIBROBLASTS Gene Knockdown Techniques Lentivirus Mast Cells Mice Mice Inbred C57BL MicroRNAs Molecular Sequence Data Oligonucleotide Array Sequence Analysis Up-Regulation
The miR-144/451 locus is required for erythroid homeostasis.
Kasper D Rasmussen, Salvatore Simmini, Cei Abreu-Goodger, Nenad Bartonicek, Monica Di Giacomo, Daniel Bilbao-Cortes, Rastislav Horos, Marieke von Lindern, Anton J Enright, Dónal O'Carroll
Jan 23, 2018
The process of erythropoiesis must be efficient and robust to supply the organism with red bloods cells both under condition of homeostasis and stress. The microRNA (miRNA) pathway was recently shown to regulate erythroid...
Large-scale identification of microRNA targets in murine Dgcr8-deficient embryonic stem cell lines.
Matthew PA Davis, Cei Abreu-Goodger, Stijn van Dongen, Dong Lu, Peri H Tate, Nenad Bartonicek, Claudia Kutter, Pentao Liu, William C Skarnes, Anton J Enright, Ian Dunham
Nov 16, 2017
Small RNAs such as microRNAs play important roles in embryonic stem cell maintenance and differentiation. A broad range of microRNAs is expressed in embryonic stem cells while only a fraction of their targets have been...
miR-221 affects multiple cancer pathways by modulating the level of hundreds messenger RNAs.
Laura Lupini, Cristian Bassi, Manuela Ferracin, Nenad Bartonicek, Lucilla D'Abundo, Barbara Zagatti, Elisa Callegari, Gentian Musa, Farzaneh Moshiri, Laura Gramantieri, Fernando J Corrales, Anton J Enright, Silvia Sabbioni, Massimo Negrini
Jan 23, 2018
microRNA miR-221 is frequently over-expressed in a variety of human neoplasms. Aim of this study was to identify new miR-221 gene targets to improve our understanding on the molecular tumor-promoting mechanisms affected by...
Pressure-Induced Enhancement of Thermoelectric Figure of Merit and Structural Phase Transition in TiNiSn.
Jason L Baker, Changyong Park, Curtis Kenney-Benson, Vineet Kumar Sharma, V Kanchana, G Vaitheeswaran, Chris J Pickard, Andrew Cornelius, Nenad Velisavljevic, Ravhi S Kumar
Jan 13, 2021
Half-Heusler thermoelectric materials are potential candidates for high thermoelectric efficiency. We report high-pressure thermoelectric and structural property measurements, density functional theory calculations on the...
The Presence of Real Food Usurps Hypothetical Health Value Judgment in Overweight People.
Nenad Medic, Hisham Ziauddeen, Suzanna E Forwood, Kirsty M Davies, Amy L Ahern, Susan A Jebb, Theresa M Marteau, Paul C Fletcher
Mar 21, 2016
eating behavior food choices Impulsivity obesity subjective value vmPFC Adolescent Adult Brain Choice Behavior Feeding Behavior Female Food Preferences Humans Image Processing Computer-Assisted Impulsive Behavior Judgment Male Models Theoretical Neuropsychological Tests Overweight Oxygen Photic Stimulation Reaction Time Taste Perception Time Factors Young Adult
Failure of sucrose replacement with the non-nutritive sweetener erythritol to alter GLP-1 or PYY release or test meal size in lean or obese people.
Joost Overduin, Tinh-Hai Collet, Nenad Medic, Elana Henning, Julia M Keogh, Faye Forsyth, Cheryl Stephenson, Marja W Kanning, Rianne MAJ Ruijschop, I Sadaf Farooqi, Agatha A van der Klaauw
Oct 28, 2016
ELF5 modulates the estrogen receptor cistrome in breast cancer.
Catherine L Piggin, Daniel L Roden, Andrew MK Law, Mark P Molloy, Christoph Krisp, Alexander Swarbrick, Matthew J Naylor, Maria Kalyuga, Warren Kaplan, Samantha R Oakes, David Gallego-Ortega, Susan J Clark, Jason S Carroll, Nenad Bartonicek, Christopher J Ormandy
Feb 13, 2020
Acquired resistance to endocrine therapy is responsible for half of the therapeutic failures in the treatment of breast cancer. Recent findings have implicated increased expression of the ETS transcription factor ELF5 as a...
Non-coding RNAs underlie genetic predisposition to breast cancer.
Mahdi Moradi Marjaneh, Jonathan Beesley, Tracy A O'Mara, Pamela Mukhopadhyay, Lambros T Koufariotis, Stephen Kazakoff, Nehal Hussein, Laura Fachal, Nenad Bartonicek, Kristine M Hillman, Susanne Kaufmann, Haran Sivakumaran, Chanel E Smart, Amy E McCart Reed, Kaltin Ferguson, Jodi M Saunus, Sunil R Lakhani, Daniel R Barnes, Antonis C Antoniou, Marcel E Dinger, Nicola Waddell, Douglas F Easton, Alison M Dunning, Georgia Chenevix-Trench, Stacey L Edwards, Juliet D French
Feb 08, 2020
BACKGROUND:Genetic variants identified through genome-wide association studies (GWAS) are predominantly non-coding and typically attributed to altered regulatory elements such as enhancers and promoters. However, the...
Published by: Genome biology
Non-coding RNAs underlie genetic predisposition to breast cancer
Mahdi Moradi Marjaneh, Jonathan Beesley, Tracy A. O’Mara, Pamela Mukhopadhyay, Lambros T. Koufariotis, Stephen Kazakoff, Nehal Hussein, Laura Fachal, Nenad Bartonicek, Kristine M. Hillman, Susanne Kaufmann, Haran Sivakumaran, Chanel E. Smart, Amy E. McCart Reed, Kaltin Ferguson, Jodi M. Saunus, Sunil R. Lakhani, Daniel R. Barnes, Antonis C. Antoniou, Marcel E. Dinger, Nicola Waddell, Douglas F. Easton, Alison M. Dunning, Georgia Chenevix-Trench, Stacey L. Edwards, Juliet D. French
Jun 06, 2020
Non-coding RNAs underlie genetic predisposition to breast cancer.
Mahdi Moradi Marjaneh, Jonathan Beesley, Tracy A O'Mara, Pamela Mukhopadhyay, Lambros T Koufariotis, Stephen Kazakoff, Nehal Hussein, Laura Fachal, Nenad Bartonicek, Kristine M Hillman, Susanne Kaufmann, Haran Sivakumaran, Chanel E Smart, Amy E McCart Reed, Kaltin Ferguson, Jodi M Saunus, Sunil R Lakhani, Daniel R Barnes, Antonis C Antoniou, Marcel E Dinger, Nicola Waddell, Douglas F Easton, Alison M Dunning, Georgia Chenevix-Trench, Stacey L Edwards, Juliet D French
Dec 16, 2019
BACKGROUND: Genetic variants identified through genome-wide association studies (GWAS) are predominantly non-coding and typically attributed to altered regulatory elements such as enhancers and promoters. However, the...
Non-coding RNAs underlie genetic predisposition to breast cancer
Mahdi Moradi Marjaneh, Jonathan Beesley, Tracy A. O’Mara, Pamela Mukhopadhyay, Lambros T. Koufariotis, Stephen Kazakoff, Nehal Hussein, Laura Fachal, Nenad Bartonicek, Kristine M. Hillman, Susanne Kaufmann, Haran Sivakumaran, Chanel E. Smart, Amy E. McCart Reed, Kaltin Ferguson, Jodi M. Saunus, Sunil R. Lakhani, Daniel R. Barnes, Antonis C. Antoniou, Marcel E. Dinger, Nicola Waddell, Douglas F. Easton, Alison M. Dunning, Georgia Chenevix-Trench, Stacey L. Edwards, Juliet D. French
Jan 06, 2021
Extent, causes, and consequences of small RNA expression variation in human adipose tissue.
Leopold Parts, Åsa K Hedman, Sarah Keildson, Andrew J Knights, Cei Abreu-Goodger, Martijn van de Bunt, José Afonso Guerra-Assunção, Nenad Bartonicek, Stijn van Dongen, Reedik Mägi, James Nisbet, Amy Barrett, Mattias Rantalainen, Alexandra C Nica, Michael A Quail, Kerrin S Small, Daniel Glass, Anton J Enright, John Winn, MuTHER Consortium, Panos Deloukas, Emmanouil T Dermitzakis, Mark I McCarthy, Timothy D Spector, Richard Durbin, Cecilia M Lindgren
Jan 18, 2018
Small RNAs are functional molecules that modulate mRNA transcripts and have been implicated in the aetiology of several common diseases. However, little is known about the extent of their variability within the human population....
Animals Blood Glucose Body Fat Distribution Body Mass Index Fasting Female Gene Expression Regulation genetic variation Genome-Wide Association Study Genotype High-Throughput Nucleotide Sequencing Humans Insulin MicroRNAs Middle Aged Polymorphism Single Nucleotide RNA Messenger RNA Small Nucleolar RNA Small Untranslated Subcutaneous Fat
Changing climate both increases and decreases European river floods
Gunter Bloschl, Julia Hall, Alberto Viglione, Rui A. P. Perdigao, Juraj Parajka, Bruno Merz, David Lun, Berit Arheimer, Guiseppe T. Aronica, Ardian Bilibashi, Milon Bohac, Ognjen Bonacci, Marco Borga, Ivan Canjevac, Attilio Castellarin, Giovanni B. Chirico, Pierluigi Claps, Natalia Frolova, Daniele Ganora, Liudmyla Gorbachova, Ali Gul, Jamie Hannaford, Shaun Harrigan, Maria Kireeva, Andrea Kiss, Thomas Kjeldsen, Silvia Kohnova, Jarkko J. Koskela, Ondrej Ledvinka, Neil Macdonald, Maria Mavrova-Guirguinova, Luis Mediero, Ralf Merz, Peter Molnar, Alberto Montanari, Conor Murphy, Marzena Osuch, Valeryia Ovcharuk, Ivan Radevski, Jose L. Salinas, Eric Sauquet, Mojca Sraj, Jan Szolgay, Elena Volpi, Donna Wilson, Klodian Zaimi, Nenad Zivkovic
Sep 05, 2019
Climate change has led to concerns about increasing river floods resulting from the greater water-holding capacity of a warmer atmosphere 1. These concerns are reinforced by evidence of increasing economic losses...
Changing climate both increases and decreases European river floods
Gunter Bloschl, Julia Hall, Alberto Viglione, Rui A. P. Perdigao, Juraj Parajka, Bruno Merz, David Lun, Berit Arheimer, Guiseppe T. Aronica, Ardian Bilibashi, Milon Bohac, Ognjen Bonacci, Marco Borga, Ivan Canjevac, Attilio Castellarin, Giovanni B. Chirico, Pierluigi Claps, Natalia Frolova, Daniele Ganora, Liudmyla Gorbachova, Ali Gul, Jamie Hannaford, Shaun Harrigan, Maria Kireeva, Andrea Kiss, Thomas Kjeldsen, Silvia Kohnova, Jarkko J. Koskela, Ondrej Ledvinka, Neil Macdonald, Maria Mavrova-Guirguinova, Luis Mediero, Ralf Merz, Peter Molnar, Alberto Montanari, Conor Murphy, Marzena Osuch, Valeryia Ovcharuk, Ivan Radevski, Jose L. Salinas, Eric Sauquet, Mojca Sraj, Jan Szolgay, Elena Volpi, Donna Wilson, Klodian Zaimi, Nenad Zivkovic
Sep 05, 2019
Climate change has led to concerns about increasing river floods resulting from the greater water-holding capacity of a warmer atmosphere 1. These concerns are reinforced by evidence of increasing economic losses...
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.
Scott E Youlten, John P Kemp, John G Logan, Elena J Ghirardello, Claudio M Sergio, Michael RG Dack, Siobhan E Guilfoyle, Victoria D Leitch, Natalie C Butterfield, Davide Komla-Ebri, Ryan C Chai, Alexander P Corr, James T Smith, Sindhu T Mohanty, John A Morris, Michelle M McDonald, Julian MW Quinn, Amelia R McGlade, Nenad Bartonicek, Matt Jansson, Konstantinos Hatzikotoulas, Melita D Irving, Ana Beleza-Meireles, Fernando Rivadeneira, Emma Duncan, J Brent Richards, David J Adams, Christopher J Lelliott, Robert Brink, Tri Giang Phan, John A Eisman, David M Evans, Eleftheria Zeggini, Paul A Baldock, JH Duncan Bassett, Graham R Williams, Peter I Croucher
Jun 07, 2021
Osteocytes are master regulators of the skeleton. We mapped the transcriptome of osteocytes from different skeletal sites, across age and sexes in mice to reveal genes and molecular programs that control this complex...
Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.
Marc Emmenegger, Elena De Cecco, David Lamparter, Raphaël PB Jacquat, Julien Riou, Dominik Menges, Tala Ballouz, Daniel Ebner, Matthias M Schneider, Itzel Condado Morales, Berre Doğançay, Jingjing Guo, Anne Wiedmer, Julie Domange, Marigona Imeri, Rita Moos, Chryssa Zografou, Leyla Batkitar, Lidia Madrigal, Dezirae Schneider, Chiara Trevisan, Andres Gonzalez-Guerra, Alessandra Carrella, Irina L Dubach, Catherine K Xu, Georg Meisl, Vasilis Kosmoliaptsis, Tomas Malinauskas, Nicola Burgess-Brown, Ray Owens, Stephanie Hatch, Juthathip Mongkolsapaya, Gavin R Screaton, Katharina Schubert, John D Huck, Feimei Liu, Florence Pojer, Kelvin Lau, David Hacker, Elsbeth Probst-Müller, Carlo Cervia, Jakob Nilsson, Onur Boyman, Lanja Saleh, Katharina Spanaus, Arnold von Eckardstein, Dominik J Schaer, Nenad Ban, Ching-Ju Tsai, Jacopo Marino, Gebhard FX Schertler, Nadine Ebert, Volker Thiel, Jochen Gottschalk, Beat M Frey, Regina R Reimann, Simone Hornemann, Aaron M Ring, Tuomas PJ Knowles, Milo A Puhan, Christian L Althaus, Ioannis Xenarios, David I Stuart, Adriano Aguzzi
Feb 09, 2023
Effective public health measures against SARS-CoV-2 require granular knowledge of population-level immune responses. We developed a Tripartite Automated Blood Immunoassay (TRABI) to assess the IgG response against three...
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