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Mind the Gap
The way organelles are viewed by cell biologists is quickly changing. For many years, these cellular entities were thought to be unique and singular structures that performed specific roles. However, in recent decades...
Colombia's Fork in the Road? President Santos' Treaty with The Revolutionary Armed Forces of Colombia (FARC)
Ella Adriana Chirinos
Aug 22, 2017
Colombia is considered Latin America’s most stable democracy; meanwhile, it is war-torn by the internal conflict with the guerrilla group, the Revolutionary Armed Forces of Colombia (FARC). The armed conflict with the FARC has...
Published by: Memorial University of Newfoundland
Paracetamol Is Associated with a Lower Risk of COVID-19 Infection and Decreased ACE2 Protein Expression
Ibuprofen is a common over-the-counter drug taken for pain relief. However, recent studies have raised concerns about its potential toxic effect with coronavirus disease 2019 (COVID-19), which is caused by severe acute...
Colombia's Fork in the Road? President Santos' Treaty with The Revolutionary Armed Forces of Colombia (FARC)
Ella Adriana Chirinos
Aug 22, 2017
Colombia is considered Latin America’s most stable democracy; meanwhile, it is war-torn by the internal conflict with the guerrilla group, the Revolutionary Armed Forces of Colombia (FARC). The armed conflict with the FARC has...
Published by: Memorial University of Newfoundland
Alzheimer's and Parkinson's Diseases Predict Different COVID-19 Outcomes
In December 2019, a coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began infecting humans, causing a novel disease, coronavirus disease 19 (COVID-19). This was first described in the Wuhan province of...
Alzheimer’s and Parkinson’s Diseases Predict Different COVID-19 Outcomes
In December 2019, a coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began infecting humans, causing a novel disease, coronavirus disease 19 (COVID-19). This was first described in the Wuhan province of...
Links between air pollution and COVID-19 in England.
Marco Travaglio, Yizhou Yu, Rebeka Popovic, Liza Selley, Nuno Santos Leal, Luis Miguel Martins
Feb 26, 2021
In December 2019, a novel disease, coronavirus disease 19 (COVID-19), emerged in Wuhan, People's Republic of China. COVID-19 is caused by a novel coronavirus (SARS-CoV-2) presumed to have jumped species from another mammal to...
Blocking dPerk in the intestine suppresses neurodegeneration in a Drosophila model of Parkinson's disease.
Rebeka Popovic, Amrita Mukherjee, Nuno Santos Leal, Lydia Morris, Yizhou Yu, Samantha H Y Loh, L Miguel Martins
Apr 17, 2023
Parkinson's disease (PD) is characterised by selective death of dopaminergic (DA) neurons in the midbrain and motor function impairment. Gastrointestinal issues often precede motor deficits in PD, indicating that the gut-brain...
Animals Drosophila Drosophila melanogaster Parkinson Disease Drosophila Proteins Unfolded Protein Response Protein Serine-Threonine Kinases
Published by: Cell Death & Disease
Blowups with log canonical singularities
We show that the minimum weight of a weighted blowup of Ad with ε–log canonical singularities is bounded by a constant depending only on ε and d . This was conjectured by Birkar. Using the recent classification of...
Blowups with log canonical singularities
We show that the minimum weight of a weighted blowup of Ad with ε–log canonical singularities is bounded by a constant depending only on ε and d . This was conjectured by Birkar. Using the recent classification of...
Amyloid Β-Peptide Increases Mitochondria-Endoplasmic Reticulum Contact Altering Mitochondrial Function and Autophagosome Formation in Alzheimer's Disease-Related Models.
Nuno Santos Leal, Giacomo Dentoni, Bernadette Schreiner, Luana Naia, Antonio Piras, Caroline Graff, Antonio Cattaneo, Giovanni Meli, Maho Hamasaki, Per Nilsson, Maria Ankarcrona
Nov 29, 2020
Recent findings have shown that the connectivity and crosstalk between mitochondria and the endoplasmic reticulum (ER) at mitochondria-ER contact sites (MERCS) are altered in Alzheimer's disease (AD) and in AD-related models....
Alzheimer’s disease Mitochondria-ER contact sites amyloid β-peptide Autophagy Mitochondria Aged Aged 80 and over Alzheimer Disease Amyloid beta-Peptides Animals Autophagosomes Brain Disease Models Animal Endoplasmic Reticulum Female Homeostasis Humans Male Mice Mice Transgenic Middle Aged Mitochondria Mitochondrial Membrane Transport Proteins Mitochondrial Membranes Neurons Up-Regulation
On the appearance of nitrite anion in [PdX(OAc)L<sub>2</sub>] and [Pd(X)(C∧N)L] syntheses (X = OAc or NO<sub>2</sub>)
S E Bajwa, T E Storr, Lauren E Hatcher, T J Williams, C G Baumann, A C Whitwood, D R Allan, S J Teat, Paul R Raithby, I J S Fairlamb
May 01, 2012
Pd 3(OAc) 5NO 2, an impurity in "Pd(OAc) 2" {formally Pd 3(OAc) 6}, emerges as a serious issue in the synthesis of pure Pd II complexes derived from Pd(OAc) 2, for example in our C-H activation precatalyst, Pd(OAc) 2(pip) 2 (pip...
Bridging pre-surgical endocrine therapy for breast cancer during the COVID-19 pandemic
Rajiv V Dave, Beatrix Elsberger, Vicky P Taxiarchi, Ashu Gandhi, Cliona C Kirwan, Baek Kim, Elizabeth M Camacho, Charlotte E Coles, Ellen Copson, Alona Courtney, Kieran Horgan, Patricia Fairbrother, Chris Holcombe, Jamie J Kirkham, Daniel R Leff, Stuart A McIntosh, Rachel O'Connell, Ricardo Pardo, Shelley Potter, Tim Rattay, Nisha Sharma, Raghavan Vidya, Ramsey I Cutress, B-MaP-C study collaborative
Apr 17, 2023
PURPOSE: The B-MaP-C study investigated changes to breast cancer care that were necessitated by the COVID-19 pandemic. Here we present a follow-up analysis of those patients commenced on bridging endocrine therapy (BrET), whilst...
On the appearance of nitrite anion in [PdX(OAc)L<sub>2</sub>] and [Pd(X)(C∧N)L] syntheses (X = OAc or NO<sub>2</sub>)
S E Bajwa, T E Storr, Lauren E Hatcher, T J Williams, C G Baumann, A C Whitwood, D R Allan, S J Teat, Paul R Raithby, I J S Fairlamb
May 01, 2012
Pd 3(OAc) 5NO 2, an impurity in "Pd(OAc) 2" {formally Pd 3(OAc) 6}, emerges as a serious issue in the synthesis of pure Pd II complexes derived from Pd(OAc) 2, for example in our C-H activation precatalyst, Pd(OAc) 2(pip) 2 (pip...
Circulating vitamin C and digestive system cancers
Susanna C Larsson, Amy M Mason, Mathew Vithayathil, Paul Carter, Siddhartha Kar, Ju-Sheng Zheng, Stephen Burgess
Sep 20, 2022
BACKGROUND & AIMS: Vitamin C is an antioxidant with a potential role in the prevention of digestive system cancers, but there is yet no consensus whether vitamin C has a causal role in these cancers. The aim of this study was to...
Breast cancer management pathways during the COVID-19 pandemic
Rajiv V Dave, Baek Kim, Alona Courtney, Rachel O'Connell, Tim Rattay, Vicky P Taxiarchi, Jamie J Kirkham, Elizabeth M Camacho, Patricia Fairbrother, Nisha Sharma, Christopher WJ Cartlidge, Kieran Horgan, Stuart A McIntosh, Daniel R Leff, Raghavan Vidya, Shelley Potter, Chris Holcombe, Ellen Copson, Charlotte E Coles, Ramsey I Cutress, Ashu Gandhi, Cliona C Kirwan, B-MaP-C study collaborative
Apr 14, 2021
BACKGROUND: The B-MaP-C study aimed to determine alterations to breast cancer (BC) management during the peak transmission period of the UK COVID-19 pandemic and the potential impact of these treatment decisions. METHODS: This...
The ALPINE–ALMA [C ii] Survey
Abstract
We present the radio properties of 66 spectroscopically confirmed normal star-forming galaxies (SFGs) at 4.4 < z < 5.9 in the COSMOS field...
Lu Shen, Brian C Lemaux, Lori M Lubin, Guilin Liu, Matthieu Béthermin, Médéric Boquien, Olga Cucciati, Olivier Le Fèvre, Margherita Talia, Daniela Vergani, Gianni Zamorani, Andreas L Faisst, Michele Ginolfi, Carlotta Gruppioni, Gareth C Jones, Sandro Bardelli, Nimish Hathi, Anton M Koekemoer, Michael Romano, Daniel Schaerer, Elena Zucca, Wenjuan Fang, Ben Forrest, Roy Gal, Denise Hung, Ekta A Shah, Priti Staab, Brittany Vanderhoof, Eduardo Ibar
Aug 24, 2022
Upgrading biogenic furans
Benzaldehyde lyase (BAL) results in an efficient biocatalyst for theumpolung carboligation of furfural, HMF, and mixtures of them,leading to blended C10–C12 platform chemicals. Subsequently, themixing and...
A Transcriptomic Analysis of Xylan Mutants Does Not Support the Existence of a Secondary Cell Wall Integrity System in Arabidopsis.
Yeast have long been known to possess a cell wall integrity (CWI) system, and recently an analogous system has been described for the primary walls of plants (PCWI) that leads to changes in plant growth and cell wall...
ISG15-Induced IL-10 Is a Novel Anti-Inflammatory Myeloid Axis Disrupted during Active Tuberculosis.
Upgrading biogenic furans
Benzaldehyde lyase (BAL) results in an efficient biocatalyst for theumpolung carboligation of furfural, HMF, and mixtures of them,leading to blended C10–C12 platform chemicals. Subsequently, themixing and...
Search for the doubly heavy baryons Ω<inf>bc</inf><sup>0</sup>and Ξ<inf>bc</inf><sup>0</sup>decaying to Λ<inf>c</inf><sup>+</sup>π- And Ξ<inf>c</inf><sup>+</sup>π- And c
C Nguyen-Mau, R Aaij, C Abellán Beteta, T Ackernley, B Adeva, M Adinolfi, H Afsharnia, CA Aidala, S Aiola, Z Ajaltouni, S Akar, J Albrecht, F Alessio, M Alexander, A Alfonso Albero, Z Aliouche, G Alkhazov, P Alvarez Cartelle, S Amato, Y Amhis, L An, L Anderlini, A Andreianov, M Andreotti, F Archilli, A Artamonov, M Artuso, K Arzymatov, E Aslanides, M Atzeni, B Audurier, S Bachmann, M Bachmayer, JJ Back, P Baladron Rodriguez, V Balagura, W Baldini, J Baptista Leite, RJ Barlow, S Barsuk, W Barter, M Bartolini, F Baryshnikov, JM Basels, G Bassi, B Batsukh, A Battig, A Bay, M Becker, F Bedeschi, I Bediaga, A Beiter, V Belavin, S Belin, V Bellee, K Belous, I Belov, I Belyaev, G Bencivenni, E Ben-Haim, A Berezhnoy, R Bernet, D Berninghoff, HC Bernstein, C Bertella, A Bertolin, C Betancourt, F Betti, I Bezshyiko, S Bhasin, J Bhom, L Bian, MS Bieker, S Bifani, P Billoir, M Birch, FCR Bishop, A Bitadze, A Bizzeti, M Bj rn, MP Blago, T Blake, F Blanc, S Blusk, D Bobulska, JA Boelhauve, O Boente Garcia, T Boettcher, A Boldyrev, A Bondar, N Bondar, S Borghi, M Borisyak, M Borsato, JT Borsuk, SA Bouchiba, TJV Bowcock, A Boyer, C Bozzi, MJ Bradley
Aug 31, 2021
The first search for the doubly heavy $\it{\Omega}_{bc}^{\rm0}$ baryon and a
search for $\it{\Xi}_{bc}^{\rm0}$ baryon are performed using $pp$ collision
data collected via the LHCb experiment from 2016 to 2018 at a...
Precision measurement of the Lambda(+)(c) baryon mass
B Aubert, R Barate, D Boutigny, F Couderc, Y Karyotakis, JP Lees, V Poireau, V Tisserand, A Zghiche, E Grauges, A Palano, M Pappagallo, A Pompili, JC Chen, ND Qi, G Rong, P Wang, YS Zhu, G Eigen, I Ofte, B Stugu, GS Abrams, M Battaglia, AB Breon, DN Brown, J Button-Shafer, RN Cahn, E Charles, CT Day, MS Gill, AV Gritsan, Y Groysman, RG Jacobsen, RW Kadel, J Kadyk, LT Kerth, YG Kolomensky, G Kukartsev, G Lynch, LM Mir, PJ Oddone, TJ Orimoto, M Pripstein, NA Roe, MT Ronan, WA Wenzel, M Barrett, KE Ford, TJ Harrison, AJ Hart, CM Hawkes, SE Morgan, AT Watson, M Fritsch, K Goetzen, T Held, H Koch, B Lewandowski, M Pelizaeus, K Peters, T Schroeder, M Steinke, JT Boyd, JP Burke, N Chevalier, WN Cottingham, T Cuhadar-Donszelmann, BG Fulsom, C Hearty, NS Knecht, TS Mattison, JA McKenna, A Khan, P Kyberd, M Saleem, L Teodorescu, AE Blinov, VE Blinov, AD Bukin, VP Druzhinin, VB Golubev, EA Kravchenko, AP Onuchin, SI Serednyakov, YI Skovpen, EP Solodov, AN Yushkov, D Best, M Bondioli, M Bruinsma, M Chao, S Curry, I Eschrich, D Kirkby, AJ Lankford, P Lund, M Mandelkern, RK Mommsen, W Roethel, DP Stoker, C Buchanan, BL Hartfiel, AJR Weinstein, SD Foulkes, JW Gary, O Long, BC Shen, K Wang, L Zhang, D Del Re, HK Hadavand, EJ Hill, DB MacFarlane, HP Paar, S Rahatlou, V Sharma, JW Berryhill, C Campagnari, A Cunha, B Dahmes, TM Hong, MA Mazur, JD Richman, W Verkerke, TW Beck, AM Eisner, CJ Flacco, CA Heusch, J Kroseberg, WS Lockman, G Nesom, T Schalk, BA Schumm, A Seiden, P Spradlin, DC Williams, MG Wilson, J Albert, E Chen, GP Dubois-Felsmann, A Dvoretskii, DG Hitlin, I Narsky, T Piatenko, FC Porter, A Ryd, A Samuel, R Andreassen, S Jayatilleke, G Mancinelli, BT Meadows, MD Sokoloff, F Blanc, P Bloom, S Chen, WT Ford, JF Hirschauer, A Kreisel, U Nauenberg, A Olivas, P Rankin, WO Ruddick, JG Smith, KA Ulmer, SR Wagner, J Zhang, A Chen, EA Eckhart, A Soffer, WH Toki, RJ Wilson, Q Zeng, D Altenburg, E Feltresi, A Hauke, B Spaan, T Brandt, J Brose, M Dickopp, V Klose, HM Lacker, R Nogowski, S Otto, A Petzold, G Schott, J Schubert, KR Schubert, R Schwierz, JE Sundermann, D Bernard, GR Bonneaud, P Grenier, S Schrenk, C Thiebaux, G Vasileiadis, M Verderi, DJ Bard, PJ Clark, W Gradl, F Muheim, S Playfer, Y Xie, M Andreotti, V Azzolini, D Bettoni, C Bozzi, R Calabrese, G Cibinetto, E Luppi, M Negrini, L Piemontese, F Anulli, R Baldini-Ferroli, A Calcaterra, R De Sangro, G Finocchiaro, P Patteri, IM Peruzzi, M Piccolo, A Zallo, A Buzzo, R Capra, R Contri, M Lo Vetere, M Macri, MR Monge, S Passaggio, C Patrignani, E Robutti, A Santroni, S Tosi, G Brandenburg, KS Chaisanguanthum, M Morii, E Won, J Wu, RS Dubitzky, U Langenegger, J Marks, S Schenk, U Uwer, W Bhimji, DA Bowerman, PD Dauncey, U Egede, RL Flack, JR Gaillard, GW Morton, JA Nash, MB Nikolich, GP Taylor, WP Vazquez, MJ Charles, WF Mader, U Mallik, AK Mohapatra, J Cochran, HB Crawley, V Eyges, WT Meyer, S Prell, EI Rosenberg, AE Rubin, J Yi, N Arnaud, M Davier, X Giroux, G Grosdidier, A Hocker, F Le Diberder, V Lepeltier, AM Lutz, A Oyanguren, TC Petersen, M Pierini, S Plaszczynski, S Rodier, P Roudeau, MH Schune, A Stocchi, G Wormser, CH Cheng, DJ Lange, MC Simani, DM Wright, AJ Bevan, CA Chavez, IJ Forster, JR Fry, E Gabathuler, R Gamet, KA George, DE Hutchcroft, RJ Parry, DJ Payne, KC Schofield, C Touramanis, CM Cormack, F Di Lodovico, W Menges, R Sacco, CL Brown, G Cowan, HU Flaecher, MG Green, DA Hopkins, PS Jackson, TR McMahon, S Ricciardi, F Salvatore, D Brown, CL Davis, J Allison, NR Barlow, RJ Barlow, CL Edgar, MC Hodgkinson, MP Kelly, GD Lafferty, MT Naisbit, JC Williams, C Chen, WD Hulsbergen, A Jawahery, D Kovalskyi, CK Lae, DA Roberts, G Simi, G Blaylock, C Dallapiccola, SS Hertzbach, R Kofler, VB Koptchev, X Li, TB Moore, S Saremi, H Staengle, S Willocq, R Cowan, K Koeneke, G Sciolla, SJ Sekula, M Spitznagel, F Taylor, RK Yamamoto, H Kim, PM Patel, SH Robertson, A Lazzaro, V Lombardo, F Palombo, JM Bauer, L Cremaldi, V Eschenburg, R Godang, R Kroeger, J Reidy, DA Sanders, DJ Summers, HW Zhao, S Brunet, D Cote, P Taras, B Viaud, H Nicholson, N Cavallo, G De Nardo, F Fabozzi, C Gatto, L Lista, D Monorchio, P Paolucci, D Piccolo, C Sciacca, M Baak, H Bulten, G Raven, HL Snoek, L Wilden, CP Jessop, JM LoSecco, T Allmendinger, G Benelli, KK Gan, K Honscheid, D Hufnagel, PD Jackson, H Kagan, R Kass, T Pulliam, AM Rahimi, R Ter-Antonyan, QK Wong, J Brau, R Frey, O Igonkina, M Lu, CT Potter, NB Sinev, D Strom, J Strube, E Torrence, F Galeazzi, M Margoni, M Morandin, M Posocco, M Rotondo, F Simonetto, R Stroili, C Voci, M Benayoun, H Briand, J Chauveau, P David, L Del Buono, C de la Vaissiere, O Hamon, MJJ John, P Leruste, J Malcles, J Ocariz, L Roos, G Therin, PK Behera, L Gladney, QH Guo, J Panetta, M Biasini, R Covarelli, S Pacetti, M Pioppi, C Angelini, G Batignani, S Bettarini, F Bucci, G Calderini, M Carpinelli, R Cenci, F Forti, MA Giorgi, A Lusiani, G Marchiori, M Morganti, N Neri, E Paoloni, M Rama, G Rizzo, J Walsh, M Haire, D Judd, DE Wagoner, J Biesiada, N Danielson, P Elmer, YP Lau, C Lu, J Olsen, AJS Smith, AV Telnov, F Bellini, G Cavoto, A D'Orazio, E Di Marco, R Faccini, F Ferrarotto, F Ferroni, M Gaspero, L Li Gioi, MA Mazzoni, S Morganti, G Piredda, F Polci, FS Tehrani, C Voena, H Schroder, G Wagner, R Waldi, T Adye, N De Groot, B Franek, GP Gopal, EO Olaiya, FF Wilson, R Aleksan, S Emery, A Gaidot, SF Ganzhur, PF Giraud, G Graziani, GH de Monchenault, W Kozanecki, M Legendre, GW London, B Mayer, G Vasseur, C Yeche, M Zito, MV Purohit, AW Weidemann, JR Wilson, FX Yumiceva, T Abe, MT Allen, D Aston, N Bakel, R Bartoldus, N Berger, AM Boyarski, OL Buchmueller, R Claus, JP Coleman, MR Convery, M Cristinziani, JC Dingfelder, D Dong, J Dorfan, D Dujmic, W Dunwoodie, S Fan, RC Field, T Glanzman, SJ Gowdy, T Hadig, V Halyo, C Hast, T Hryn'ova, WR Innes, MH Kelsey, P Kim, ML Kocian, DWGS Leith, J Libby, S Luitz, V Luth, HL Lynch, H Marsiske, R Messner, DR Muller, CP O'Grady, VE Ozcan, A Perazzo, M Perl, BN Ratcliff, A Roodman, AA Salnikov, RH Schindler, J Schwiening, A Snyder, J Stelzer, D Su, MK Sullivan, K Suzuki, S Swain, JM Thompson, J Va'Vra, M Weaver, WJ Wisniewski, M Wittgen, DH Wright, AK Yarritu, K Yi, CC Young, PR Burchat, AJ Edwards, SA Majewski, BA Petersen, C Roat, M Ahmed, S Ahmed, MS Alam, JA Ernst, MA Saeed, FR Wappler, SB Zain, W Bugg, M Krishnamurthy, SM Spanier, R Eckmann, JL Ritchie, A Satpathy, RF Schwitters, JM Izen, I Kitayama, XC Lou, S Ye, F Bianchi, M Bona, F Gallo, D Gamba, M Bomben, L Bosisio, C Cartaro, F Cossutti, G Della Ricca, S Dittongo, S Grancagnolo, L Lanceri, L Vitale, F Martinez-Vidal, RS Panvini, S Banerjee, B Bhuyan, CM Brown, D Fortin, K Hamano, R Kowalewski, JM Roney, RJ Sobie, JJ Back, PF Harrison, TE Latham, GB Mohanty, HR Band, X Chen, B Cheng, S Dasu, M Datta, AM Eichenbaum, KT Flood, M Graham, JJ Hollar, JR Johnson, PE Kutter, H Li, R Liu, B Mellado, A Mihalyi, Y Pan, R Prepost, P Tan, JH von Wimmersperg-Toeller, SL Wu, Z Yu, H Neal, BaBar Collaboration
Jul 28, 2021
A precision measurement of the $B_{c}^{+}$ meson mass is performed using
proton-proton collision data collected with the LHCb experiment at
centre-of-mass energies of $7, 8$ and $13$ TeV, corresponding to a total
integrated...
Selective Dealkenylative Functionalization of Styrenes via C-C Bond Cleavage.
As a readily available feedstock, styrene with about 25 million tons of global annual production serves as an important building block and organic synthon for the synthesis of fine chemicals, polystyrene plastics, and...
Carbothermal reduction of mill scales formed on steel billets during continuous casting
S. M. Espinoza Suarez, L. E. Borja-Castro, M. I. Valerio-Cuadros, A. Bustamante Domínguez, H. A. Cabrera-Tinoco, E. Huaman, R. A. Valencia-Bedregal, Xiaoli Zhao, Youyun Zhang, Deliang Zhang, C. H. W. Barnes, L. De Los Santos Valladares
Nov 22, 2021
Abstract: A billet is a bar made from crude steel which surface contains scales which are rich in iron oxides. This study presents the carbothermal reduction of the scales formed in steel billets. The process included the...
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