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Purification and Characterization of Nickel Uptake Regulator (NUR) and Single NUR Mutants from <em>Streptomyces coelicolor</em>
The Nickel Uptake Regulator (NUR) is a metalloregulatory protein found in the microorganism Streptomyces coelicolor. S.coelicolor is a gram-positive bacterium that plays an important role in antibiotic production. NUR is...
Published by: Winthrop University
Cloning and characterization of nickel uptake regulator NUR mutants from <em>Streptomyces coelicolor</em>
Sufficient concentrations of metal within a cell are required for proper cellular function; however, metals become toxic at very high concentrations. Therefore, it is important for an organism to have a mechanism for maintaining...
Published by: Winthrop University
Rheumatology, collaboration, and modern-day research
Benjamin Edwards
Jan 01, 2023
An interview with Dr. Proton Rahman, a rheumatologist, genetic epidemiologist, and professor at Memorial University. Dr. Rahman has been working in the province for the past 24 years and in addition to his clinical work, has...
Published by: Memorial University Libraries
Rheumatology, collaboration, and modern-day research
Benjamin Edwards
Jan 01, 2023
An interview with Dr. Proton Rahman, a rheumatologist, genetic epidemiologist, and professor at Memorial University. Dr. Rahman has been working in the province for the past 24 years and in addition to his clinical work, has...
Published by: Memorial University Libraries
Erratum:Compounds Related to Saudin and Three New Series of Diterpenoids from Clutia lanceolata (Journal of Natural Products (2023) 86: 5 (1129−1149) DOI
Sarfaraz Ahmed, Mohammad Nur-E-Alam, Ifat Parveen, Michael Threadgill, James B. Orton, Rahman M. Hafizur, Israr Khan, Mai Al-Oqail, Adnan J. Al-Rehaily
Oct 27, 2023
Re-examination and reinterpretation of the NOESY NMR data for 11 and 12 has led to reassignment of the relative stereochemical configurations at C-5 and C-10 for both compounds. The text discussing the relative configurations...
Erratum:Compounds Related to Saudin and Three New Series of Diterpenoids from Clutia lanceolata (Journal of Natural Products (2023) 86: 5 (1129−1149) DOI
Sarfaraz Ahmed, Mohammad Nur-E-Alam, Ifat Parveen, Michael Threadgill, James B. Orton, Rahman M. Hafizur, Israr Khan, Mai Al-Oqail, Adnan J. Al-Rehaily
Oct 27, 2023
Re-examination and reinterpretation of the NOESY NMR data for 11 and 12 has led to reassignment of the relative stereochemical configurations at C-5 and C-10 for both compounds. The text discussing the relative configurations...
New flavonoids from the Saudi Arabian plant
Mohammad Nur-E-Alam, Muhammad Yousaf, Ifat Parveen, Rahman Hafizur, Usman Ghani, Sarfaraz Ahmed, Abdul Hameed, Michael Threadgill, Adnan N. Al-Rehaily
Feb 07, 2019
Retama raetam is a bush which is a member of the family Fabaceae. It is used traditionally in North Africa and Saudi Arabia for the treatment of diabetes. Several flavonoids and alkaloids are already known from this plant....
/dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1600/1606 name=Physical and Theoretical Chemistry /dk/atira/pure/subjectarea/asjc/1600/1605 name=Organic Chemistry /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
New flavonoids from the Saudi Arabian plant
Mohammad Nur-E-Alam, Muhammad Yousaf, Ifat Parveen, Rahman Hafizur, Usman Ghani, Sarfaraz Ahmed, Abdul Hameed, Michael Threadgill, Adnan N. Al-Rehaily
Feb 07, 2019
Retama raetam is a bush which is a member of the family Fabaceae. It is used traditionally in North Africa and Saudi Arabia for the treatment of diabetes. Several flavonoids and alkaloids are already known from this plant....
/dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1600/1606 name=Physical and Theoretical Chemistry /dk/atira/pure/subjectarea/asjc/1600/1605 name=Organic Chemistry /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
The road to recovery
Lindsay F Banin, Elizabeth H Raine, Lucy M Rowland, Robin L Chazdon, Stuart W Smith, Nur Estya Binte Rahman, Adam Butler, Christopher Philipson, Grahame G Applegate, E Petter Axelsson, Sugeng Budiharta, Siew Chin Chua, Mark EJ Cutler, Stephen Elliott, Elva Gemita, Elia Godoong, Laura LB Graham, Robin M Hayward, Andy Hector, Ulrik Ilstedt, Joel Jensen, Srinivasan Kasinathan, Christopher J Kettle, Daniel Lussetti, Benjapan Manohan, Colin Maycock, Kang Min Ngo, Michael J O'Brien, Anand M Osuri, Glen Reynolds, Yap Sauwai, Stefan Scheu, Mangarah Silalahi, Eleanor M Slade, Tom Swinfield, David A Wardle, Charlotte Wheeler, Kok Loong Yeong, David FRP Burslem
Dec 15, 2022
Current policy is driving renewed impetus to restore forests to return ecological function, protect species, sequester carbon and secure livelihoods. Here we assess the contribution of tree planting to ecosystem restoration in...
Stimulation of insulin secretion by 5-methylcoumarins and its sulfur analogues isolated from Clutia lanceolata Forssk
Sarfaraz Ahmed, Mohammad Nur-E-Alam, Ifat Parveen, Simon J. Coles, Rahman M. Hafizur, Abdul Hameed, James B. Orton, Michael D. Threadgill, Muhammad Yousaf, Abdulaziz M. Alqahtani, Adnan J. Al-Rehaily
Feb 01, 2020
Clutia lanceolata Forssk. (C. lanceolata) is a medicinal plant native to sub-Saharan Africa and the Arabian Peninsula. Phytochemical investigation of the aerial parts of C. lanceolata yielded twenty-one coumarins including...
Clutia lanceolata Forssk Coumarins Insulin Methylthiocoumarins Murine islets Peraceae Single X-ray crystallography /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1312 name=Molecular Biology /dk/atira/pure/subjectarea/asjc/1100/1110 name=Plant Science /dk/atira/pure/subjectarea/asjc/1100/1108 name=Horticulture /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
A neoclerodane orthoester and other new neoclerodane diterpenoids from <i>Teucrium yemense</i> chemistry and effect on secretion of insulin
Mohammad Nur-E-Alam, Ifat Parveen, Barrie Wilkinson, Sarfaraz Ahmed, Rahman M. Hafizur, Ahmed Bari, Timothy Woodman, Michael Threadgill, Adnan J. Al-Rehaily
Apr 13, 2021
Teucrium yemense, a medicinal plant commonly grown in Saudi Arabia and Yemen, is traditionally used
to treat infections, kidney diseases, rheumatism, and diabetes. Extraction of the dried aerial parts
of the...
to treat infections, kidney diseases, rheumatism, and diabetes. Extraction of the dried aerial parts
of the...
A neoclerodane orthoester and other new neoclerodane diterpenoids from <i>Teucrium yemense</i> chemistry and effect on secretion of insulin
Mohammad Nur-E-Alam, Ifat Parveen, Barrie Wilkinson, Sarfaraz Ahmed, Rahman M. Hafizur, Ahmed Bari, Timothy Woodman, Michael Threadgill, Adnan J. Al-Rehaily
Apr 13, 2021
Teucrium yemense, a medicinal plant commonly grown in Saudi Arabia and Yemen, is traditionally used
to treat infections, kidney diseases, rheumatism, and diabetes. Extraction of the dried aerial parts
of the...
to treat infections, kidney diseases, rheumatism, and diabetes. Extraction of the dried aerial parts
of the...
The road to recovery
Lindsay F Banin, Elizabeth H Raine, Lucy M Rowland, Robin L Chazdon, Stuart W Smith, Nur Estya Binte Rahman, Adam Butler, Christopher Philipson, Grahame G Applegate, E Petter Axelsson, Sugeng Budiharta, Siew Chin Chua, Mark EJ Cutler, Stephen Elliott, Elva Gemita, Elia Godoong, Laura LB Graham, Robin M Hayward, Andy Hector, Ulrik Ilstedt, Joel Jensen, Srinivasan Kasinathan, Christopher J Kettle, Daniel Lussetti, Benjapan Manohan, Colin Maycock, Kang Min Ngo, Michael J O'Brien, Anand M Osuri, Glen Reynolds, Yap Sauwai, Stefan Scheu, Mangarah Silalahi, Eleanor M Slade, Tom Swinfield, David A Wardle, Charlotte Wheeler, Kok Loong Yeong, David FRP Burslem
Nov 15, 2022
Stimulation of insulin secretion by 5-methylcoumarins and its sulfur analogues isolated from Clutia lanceolata Forssk
Sarfaraz Ahmed, Mohammad Nur-E-Alam, Ifat Parveen, Simon J. Coles, Rahman M. Hafizur, Abdul Hameed, James B. Orton, Michael D. Threadgill, Muhammad Yousaf, Abdulaziz M. Alqahtani, Adnan J. Al-Rehaily
Feb 01, 2020
Clutia lanceolata Forssk. (C. lanceolata) is a medicinal plant native to sub-Saharan Africa and the Arabian Peninsula. Phytochemical investigation of the aerial parts of C. lanceolata yielded twenty-one coumarins including...
Clutia lanceolata Forssk Coumarins Insulin Methylthiocoumarins Murine islets Peraceae Single X-ray crystallography /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1312 name=Molecular Biology /dk/atira/pure/subjectarea/asjc/1100/1110 name=Plant Science /dk/atira/pure/subjectarea/asjc/1100/1108 name=Horticulture /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Management Progression and Prospects- A Comparative Global and Historical Overview of the National and Multinational Organizations in the Context of Pakistani Business Environment
Organizations are essential entity for the survival and sustainability of an economy. In today’s dynamic world the survival of an organization itself is big challenge in the face of unpredictable threat, challenges and...
Published by: Department of History, University of Karachi
Village Financial Transparency And Accountability (Empirical Study in Disadvantaged Villages in West Halmahera Regency)
This study aims to reveal the application of the principles of Transparency and Accountability in the administration of Village Government which is categorized as Disadvantaged in West Halmahera Regency. Transparency is related...
Published by: Indonesia Strategic Sustainability
Factor Influence Mental In Adolences
The mental condition of adolescents and children in Indonesia is currently alarming. Adolescents are vulnerable to various problems at the stage of development, such as mental and emotional problems related to emotional...
Published by: Indonesia Strategic Sustainability
A stochastic programming approach for chemotherapy appointment scheduling
Chemotherapy appointment scheduling is a challenging problem due to the uncertainty in premedication and infusion durations. In this paper, we formulate a two‐stage stochastic mixed integer programming model for the chemotherapy...
appointment scheduling Chemotherapy progressive hedging scheduling stochastic programming /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2600/2611 name=Modelling and Simulation /dk/atira/pure/subjectarea/asjc/1800/1803 name=Management Science and Operations Research
A stochastic programming approach for chemotherapy appointment scheduling
Chemotherapy appointment scheduling is a challenging problem due to the uncertainty in premedication and infusion durations. In this paper, we formulate a two‐stage stochastic mixed integer programming model for the chemotherapy...
appointment scheduling Chemotherapy progressive hedging scheduling stochastic programming /dk/atira/pure/subjectarea/asjc/2200/2212 name=Ocean Engineering /dk/atira/pure/subjectarea/asjc/2600/2611 name=Modelling and Simulation /dk/atira/pure/subjectarea/asjc/1800/1803 name=Management Science and Operations Research
Behaviour and Bot Analysis on Online Social Networks
The internet is home to a multitude of social networks that provide users with a sense of community and connection across the world. Among these, Twitter and Reddit are two of the most popular. While Twitter users follow and...
Published by: IGI Global Scientific Publishing
Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation.
Li Ren Kong, Richard Weijie Ong, Tuan Zea Tan, Nur Afiqah Binte Mohamed Salleh, Matan Thangavelu, Jane Vin Chan, Lie Yong Judice Koh, Giridharan Periyasamy, Jieying Amelia Lau, Thi Bich Uyen Le, Lingzhi Wang, MiYoung Lee, Srinivasaraghavan Kannan, Chandra S Verma, Chwee Ming Lim, Wee Joo Chng, David P Lane, Ashok Venkitaraman, Huynh The Hung, Chit Fang Cheok, Boon Cher Goh
May 15, 2020
Gain of function (GOF) DNA binding domain (DBD) mutations of TP53 upregulate chromatin regulatory genes that promote genome-wide histone methylation and acetylation. Here, we therapeutically exploit the oncogenic GOF mechanisms...
Acetylation Animals Antineoplastic Agents Apoptosis Caspase 3 Cell Line Tumor Cell Proliferation cisplatin Codon Epigenesis Genetic Gain of Function Mutation Gene Expression Regulation Neoplastic Humans Hydroxamic Acids Mice SCID Models Biological Mutant Proteins Mutation NF-kappa B Neoplasms Nucleotide Motifs Poly(ADP-ribose) Polymerases Protein Binding Protein Isoforms Sulfonamides Topotecan Tumor Suppressor Protein p53 Ubiquitin-Protein Ligases Xenograft Model Antitumor Assays
Optimizing The Performance Of Village Owned Enterprises
This study aims to build a model for optimizing the performance of Village Owned Enterprises in the West Halmahera Regency. As a result of all that the existence of BUMDes has not been able to contribute to Village Original...
Published by: Indonesia Strategic Sustainability
Factor Influence Mental In Adolences
The mental condition of adolescents and children in Indonesia is currently alarming. Adolescents are vulnerable to various problems at the stage of development, such as mental and emotional problems related to emotional...
Published by: Indonesia Strategic Sustainability
Training Effectiveness in Times of Austerity
Due to the fall in oil price, many companies are looking into ways to cut cost. Despite such cost-cutting efforts fuelled by the constant pressure for companies to stay competitive, the importance of training is still widely...
Published by: IGI Global Scientific Publishing
Unveiling some FDA-approved drugs as inhibitors of the store-operated Ca2+ entry pathway.
The store-operated calcium entry (SOCE) pathway is an important route for generating cytosolic Ca2+ signals that regulate a diverse array of biological processes. Abnormal SOCE seem to underlie several diseases that notably...
Anilides Animals Biological Assay Calcium Calcium Signaling Cell Nucleus Drug Approval Drug Evaluation Preclinical HEK293 Cells HeLa Cells Humans Ion Channel Gating Ligands NFATC Transcription Factors ORAI1 Protein Protein Multimerization Protein Transport Rats Stromal Interaction Molecule 1 Thapsigargin Thiadiazoles United States United States Food and Drug Administration User-Computer Interface
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