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The interplay between magnetism and superconductivity can lead to unconventional proximity and Josephson effects. A related phenomenon that has recently attracted considerable attention is the superconducting diode effect, in...

article /639/301/119/1003 /639/301/119/2793 /639/925/927/1064 /639/766/119/544 /639/766/119/995 article

EXCHANGE FIELD HETEROSTRUCTURES NANOSTRUCTURES SUPERCURRENTS films WAVE

Cellulose, a major constituent of our natural environment and a structured biodegradable biopolymer, has been shown to exhibit shear piezoelectricity with potential applications in energy harvesters, biomedical sensors...

0912 Materials Engineering Nanotechnology Bioengineering

RESEARCH ARTICLE Alzheimer’s disease amyloid β protein aggregation lipid membranes aggregation kinetics cryo-electron microscopy

Misfolded α-synuclein oligomers are closely implicated in the pathology of Parkinson's disease and related synucleinopathies. The elusive nature of these aberrant assemblies makes it challenging to develop quantitative methods...

Parkinson's Disease Brain Disorders Biotechnology Acquired Cognitive Impairment aging Neurosciences Neurodegenerative 2 Aetiology 2.1 Biological and endogenous factors Neurological

cond-mat.supr-con cond-mat.supr-con cond-mat.mtrl-sci

Alzheimer’s disease aggregation kinetics amyloid β cryo-electron microscopy lipid membranes protein aggregation Humans Amyloid beta-Peptides Kinetics Biomimetics Alzheimer Disease Lipid Bilayers Peptide Fragments

Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial outer membrane porin, PorB, which is essential for ion...

Animals Apoptosis Cell Membrane Gonorrhea Humans MACROPHAGES Membrane potential Mitochondrial Mice Mice Inbred C57BL Mitochondria Neisseria gonorrhoeae Porins

Inactivation of APC is a strongly predisposing event in the development of colorectal cancer, prompting the search for vulnerabilities specific to cells that have lost APC function. Signalling through the mTOR pathway is known...

Adenomatous Polyposis Coli Protein Animals Cell Proliferation Cell Transformation Neoplastic Elongation Factor 2 Kinase Enzyme Activation Genes APC Intestinal Neoplasms Male Mechanistic Target of Rapamycin Complex 1 Mice Mice Inbred C57BL Multiprotein Complexes Oncogene Protein p55(v-myc) Peptide Chain Elongation Translational Peptide Elongation Factor 2 Ribosomal Protein S6 Kinases Signal Transduction TOR Serine-Threonine Kinases Wnt Proteins

Members of the ATP-binding cassette (ABC) transporter superfamily translocate a broad spectrum of chemically diverse substrates. While their eponymous ATP-binding cassette in the nucleotide-binding domains (NBDs) is highly...

ABC transporters ATPases X-ray crystallography cryo-EM Membrane Proteins molecular machines Phylogeny primary active transporters Sequence Alignment structural biology ATP-Binding Cassette Transporters Protein Domains Protein Folding