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Results: 20136
Surface dissolution UV imaging for characterization of superdisintegrants and their impact on drug dissolution
Superdisintegrants are a key excipient used in immediate release formulations to promote fast tablet disintegration, therefore understanding the impact of superdisintegrant variability on product performance is important. The...
Surface dissolution UV imaging for characterization of superdisintegrants and their impact on drug dissolution
Superdisintegrants are a key excipient used in immediate release formulations to promote fast tablet disintegration, therefore understanding the impact of superdisintegrant variability on product performance is important. The...
Biopharmaceutical implications of excipient variability on drug dissolution from immediate release products
Elucidating the impact of excipient variability on oral product performance in a biopharmaceutical perspective would be beneficial and allow excipient implementation on Quality by Design (QbD) approaches. The current study...
Biopharmaceutical implications of excipient variability on drug dissolution from immediate release products
Elucidating the impact of excipient variability on oral product performance in a biopharmaceutical perspective would be beneficial and allow excipient implementation on Quality by Design (QbD) approaches. The current study...
Investigation of drug partition kinetics to fat in simulated fed state gastric conditions based on drug properties
The presence of fat in the gastric environment can affect the pharmacokinetic behaviour of drugs with mechanisms which have not been yet fully understood. The objective of the current study was to assess the drug partition to...
Affinity of Lipophilic Drugs to Mixed Lipid Aggregates in Simulated Gastrointestinal Fluids
Mixed lipid aggregates, comprising of bile salts and phospholipids, present in the small intestine assist in drug solubilization and subsequent drug dissolution and absorption through the intestinal epithelium. The increased...
Interview with Gwen P. Howell
Gwen P. Howell
Jan 01, 0001
Interview with Gwen P. Howell, member of the South Carolina Mothers Association.
Published by: Winthrop University
Affinity of Lipophilic Drugs to Mixed Lipid Aggregates in Simulated Gastrointestinal Fluids
Mixed lipid aggregates, comprising of bile salts and phospholipids, present in the small intestine assist in drug solubilization and subsequent drug dissolution and absorption through the intestinal epithelium. The increased...
Investigation of drug partition kinetics to fat in simulated fed state gastric conditions based on drug properties
The presence of fat in the gastric environment can affect the pharmacokinetic behaviour of drugs with mechanisms which have not been yet fully understood. The objective of the current study was to assess the drug partition to...
PSK Method for Solving Mixed and Type-4 Intuitionistic Fuzzy Solid Transportation Problems
P. Kumar
Apr 01, 2019
In this article, the author categorises the solid transportation problem (STP) under uncertain environments. He formulates the mixed and fully intuitionistic fuzzy solid transportation problems (FIFSTPs) and utilizes the...
Published by: IGI Global Scientific Publishing
Diabetes Prediction Using Enhanced SVM and Deep Neural Network Learning Techniques: An Algorithmic Approach for Early Screening of Diabetes
Diabetes, caused by the rise in level of glucose in blood, has many latest devices to identify from blood samples. Diabetes, when unnoticed, may bring many serious diseases like heart attack, kidney disease. In this way, there...
Published by: IGI Global Scientific Publishing
Measurement of the η<inf>c</inf>(1 S) production cross-section in p p collisions at √s=13TeV
R Aaij, CA Beteta, T Ackernley, B Adeva, M Adinolfi, H Afsharnia, CA Aidala, S Aiola, Z Ajaltouni, S Akar, P Albicocco, J Albrecht, F Alessio, M Alexander, AA Albero, G Alkhazov, PA Cartelle, AA Alves, S Amato, Y Amhis, L An, L Anderlini, G Andreassi, M Andreotti, F Archilli, P d’Argent, JA Romeu, A Artamonov, M Artuso, K Arzymatov, E Aslanides, M Atzeni, B Audurier, S Bachmann, JJ Back, S Baker, V Balagura, W Baldini, A Baranov, RJ Barlow, S Barsuk, W Barter, M Bartolini, F Baryshnikov, G Bassi, V Batozskaya, B Batsukh, A Battig, V Battista, A Bay, M Becker, F Bedeschi, I Bediaga, A Beiter, LJ Bel, V Belavin, S Belin, N Beliy, V Bellee, K Belous, I Belyaev, E Ben-Haim, G Bencivenni, S Benson, S Beranek, A Berezhnoy, R Bernet, D Berninghoff, HC Bernstein, E Bertholet, A Bertolin, C Betancourt, F Betti, MO Bettler, MV Beuzekom, I Bezshyiko, S Bhasin, J Bhom, MS Bieker, S Bifani, P Billoir, A Birnkraut, A Bizzeti, M Bjørn, MP Blago, T Blake, F Blanc, S Blusk, D Bobulska, V Bocci, OB Garcia, T Boettcher, A Boldyrev, A Bondar, N Bondar, S Borghi, M Borisyak, M Borsato, JT Borsuk, M Boubdir
Mar 02, 2021
Using a data sample corresponding to an integrated luminosity of
$2.0\,fb^{-1}$, collected by the LHCb experiment, the production of the
$\eta_c(1S)$ state in proton-proton collisions at a centre-of-mass energy of
$\sqrt{s}=13...
Empirical Investigation to Assess the Impact of ICT Deployment in SCM Using SEM
The adoption of Information & Communication Technology (ICT) is becoming increasingly ubiquitous and it is prominent in Supply Chain too. The objective of this paper is to perform an empirical investigation to assess the impact...
Published by: IGI Global Scientific Publishing
The Synthetic Chemistry of Carboxyalkyl-P, P-Diphenyl Phosphines
Larry S. Andrews
Jan 01, 0001
This 55 page thesis examines the preparation of carboxyalkyl-P and P-diphenyl phosphines to determine their acidity characteristics as a function of structure and to characterize their ability to function as chelating agents.
potassium diphenylphosphine sodium liquid ammonia Acidity Synthesis Chemistry Physical Sciences and Mathematics
Published by: Ursinus College
Intrinsically p-biharmonic maps
For a compact Riemannian manifold $N$, a domain $\Omega \subset \mathbb{R}^m$ and for $p \in (1,\infty)$, we introduce an intrinsic version $E_p$ of the $p$-biharmonic energy functional for maps $u : \Omega \to N$. This requires...
Biopharmaceutical aspects and implications of excipient variability in drug product performance
Implementation of Quality by Design approaches in pharmaceutical industry requires a sound understanding of the parameters triggering final product variability. Excipients, although generally regarded as inert components, are of...
Intrinsically p-biharmonic maps
For a compact Riemannian manifold $N$, a domain $\Omega \subset \mathbb{R}^m$ and for $p \in (1,\infty)$, we introduce an intrinsic version $E_p$ of the $p$-biharmonic energy functional for maps $u : \Omega \to N$. This requires...
Observation of the decay Lambda b0 -> chi(c1)p pi(-)
R Aaij, C Abellan Beteta, B Adeva, M Adinolfi, CA Aidala, Z Ajaltouni, S Akar, P Albicocco, J Albrecht, F Alessio, M Alexander, A Alfonso Albero, G Alkhazov, P Alvarez Cartelle, AA Jr Alves, S Amato, S Amerio, Y Amhis, L An, L Anderlini, G Andreassi, M Andreotti, JE Andrews, F Archilli, P D'Argent, J Arnau Romeu, A Artamonov, M Artuso, K Arzymatov, E Aslanides, M Atzeni, B Audurier, S Bachmann, JJ Back, S Baker, V Balagura, W Baldini, A Baranov, RJ Barlow, GC Barrand, S Barsuk, W Barter, M Bartolini, F Baryshnikov, V Batozskaya, B Batsukh, A Battig, V Battista, A Bay, J Beddow, F Bedeschi, I Bediaga, A Beiter, LJ Bel, S Belin, N Beliy, V Bellee, N Belloli, K Belous, I Belyaev, E Ben-Haim, G Bencivenni, S Benson, S Beranek, A Berezhnoy, R Bernet, D Berninghoff, E Bertholet, A Bertolin, C Betancourt, F Betti, MO Bettler, M van Beuzekom, Ia Bezshyiko, S Bhasin, J Bhom, S Bifani, P Billoir, A Birnkraut, A Bizzeti, M Bjorn, MP Blago, T Blake, F Blanc, S Blusk, D Bobulska, V Bocci, O Boente Garcia, T Boettcher, A Bondar, N Bondar, S Borghi, M Borisyak, M Borsato, F Bossu, M Boubdir, TJV Bowcock, C Bozzi, S Braun, M Brodski, J Brodzicka, A Brossa Gonzalo, D Brundu, E Buchanan, A Buonaura, C Burr, A Bursche, J Buytaert, W Byczynski, S Cadeddu, H Cai, R Calabrese, R Calladine, M Calvi, M Calvo Gomez, A Camboni, P Campana, DH Campora Perez, L Capriotti, A Carbone, G Carboni, R Cardinale, A Cardini, P Carniti, K Carvalho Akiba, G Casse, L Cassina, M Cattaneo, G Cavallero, R Cenci, D Chamont, MG Chapman, M Charles, Ph Charpentier, G Chatzikonstantinidis, M Chefdeville, V Chekalina, C Chen, S Chen, S-G Chitic, V Chobanova, M Chrzaszcz, A Chubykin, P Ciambrone, X Cid Vidal, G Ciezarek, F Cindolo, PEL Clarke, M Clemencic, HV Cliff, J Closier, V Coco, JAB Coelho, J Cogan, E Cogneras, L Cojocariu, P Collins, T Colombo, A Comerma-Montells, A Contu, G Coombs, S Coquereau, G Corti, M Corvo, CM Costa Sobral, B Couturier, GA Cowan, DC Craik, A Crocombe, M Cruz Torres, R Currie, C D'Ambrosio, F Da Cunha Marinho, CL Da Silva, E Dall'Occo, J Dalseno, A Danilina, A Davis, O De Aguiar Francisco, K De Bruyn, S De Capua, M De Cian, JM De Miranda, L De Paula, M De Serio, P De Simone, CT Dean, D Decamp, L Del Buono, B Delaney, H-P Dembinski, M Demmer, A Dendek, D Derkach, O Deschamps, F Desse, F Dettori, B Dey, A Di Canto, P Di Nezza, S Didenko, H Dijkstra, F Dordei, M Dorigo, A Dosil Suarez, L Douglas, A Dovbnya, K Dreimanis, L Dufour, G Dujany, P Durante, JM Durham, D Dutta, R Dzhelyadin, M Dziewiecki, A Dziurda, A Dzyuba, S Easo, U Egede, V Egorychev, S Eidelman, S Eisenhardt, U Eitschberger, R Ekelhof, L Eklund, S Ely, A Ene, S Escher, S Esen, T Evans, A Falabella, N Farley, S Farry, D Fazzini, P Fernandez Declara, A Fernandez Prieto, F Ferrari, L Ferreira Lopes, F Ferreira Rodrigues, M Ferro-Luzzi, S Filippov, RA Fini, M Fiorini, M Firlej, C Fitzpatrick, T Fiutowski, F Fleuret, M Fontana, F Fontanelli, R Forty, V Franco Lima, M Frank, C Frei, J Fu, W Funk, C Farber, M Feo, E Gabriel, A Gallas Torreira, D Galli, S Gallorini, S Gambetta, Y Gan, M Gandelman, P Gandini, Y Gao, LM Garcia Martin, B Garcia Plana, J Garcia Pardinas, J Garra Tico, L Garrido, D Gascon, C Gaspar, L Gavardi, G Gazzoni, D Gerick, E Gersabeck, M Gersabeck, T Gershon, D Gerstel, Ph Ghez, V Gibson, OG Girard, P Gironella Gironell, L Giubega, K Gizdov, VV Gligorov, D Golubkov, A Golutvin, A Gomes, IV Gorelov, C Gotti, E Govorkova, JP Grabowski, R Graciani Diaz, LA Granado Cardoso, E Grauges, E Graverini, G Graziani, A Grecu, R Greim, P Griffith, L Grillo, L Gruber, BR Gruberg Cazon, O Gruenberg, C Gu, E Gushchin, A Guth, Yu Guz, T Gys, C Gobel, T Hadavizadeh, C Hadjivasiliou, G Haefeli, C Haen, SC Haines, B Hamilton, X Han, TH Hancock, S Hansmann-Menzemer, N Harnew, T Harrison, C Hasse, M Hatch, J He, M Hecker, K Heinicke, A Heister, K Hennessy, L Henry, E van Herwijnen, J Heuel, M Heß, A Hicheur, R Hidalgo Charman, D Hill, M Hilton, PH Hopchev, J Hu, W Hu, W Huang, ZC Huard, W Hulsbergen, T Humair, M Hushchyn, D Hutchcroft, D Hynds, P Ibis, M Idzik, P Ilten, A Inglessi, A Inyakin, K Ivshin, R Jacobsson, J Jalocha, E Jans, BK Jashal, A Jawahery, F Jiang, M John, D Johnson, CR Jones, C Joram, B Jost, N Jurik, S Kandybei, M Karacson, JM Kariuki, S Karodia, N Kazeev, M Kecke, F Keizer, M Kelsey, M Kenzie, T Ketel, E Khairullin, B Khanji, C Khurewathanakul, KE Kim, T Kirn, VS Kirsebom, S Klaver, K Klimaszewski, T Klimkovich, S Koliiev, M Kolpin, R Kopecna, P Koppenburg, I Kostiuk, S Kotriakhova, M Kozeiha, L Kravchuk, M Kreps, F Kress, P Krokovny, W Krupa, W Krzemien, W Kucewicz, M Kucharczyk, V Kudryavtsev, AK Kuonen, T Kvaratskheliya, D Lacarrere, G Lafferty, A Lai, D Lancierini, G Lanfranchi, C Langenbruch, T Latham, C Lazzeroni, R Le Gac, Le At, R Lefevre, F Lemaitre, O Leroy, T Lesiak, B Leverington, P-R Li, Y Li, Z Li, X Liang, T Likhomanenko, R Lindner, F Lionetto, V Lisovskyi, G Liu, X Liu, D Loh, A Loi, I Longstaff, JH Lopes, GH Lovell, D Lucchesi, M Lucio Martinez, A Lupato, E Luppi, O Lupton, A Lusiani, X Lyu, F Machefert, F Maciuc, V Macko, P Mackowiak, S Maddrell-Mander, O Maev, K Maguire, D Maisuzenko, MW Majewski, S Malde, B Malecki, A Malinin, T Maltsev, G Manca, G Mancinelli, D Marangotto, J Maratas, JF Marchand, U Marconi, C Marin Benito, M Marinangeli, P Marino, J Marks, PJ Marshall, G Martellotti, M Martinelli, D Martinez Santos, F Martinez Vidal, A Massafferri, M Materok, R Matev, A Mathad, Z Mathe, C Matteuzzi, A Mauri, E Maurice, B Maurin, M McCann, A McNab, R McNulty, JV Mead, B Meadows, C Meaux, N Meinert, D Melnychuk, M Merk, A Merli, E Michielin, DA Milanes, E Millard, M-N Minard, L Minzoni, DS Mitzel, A Mogini, RD Moise, T Mombaecher, IA Monroy, S Monteil, M Morandin, G Morello, MJ Morello, O Morgunova, J Moron, AB Morris, R Mountain, F Muheim, M Mukherjee, M Mulder, CH Murphy, D Murray, A Moedden, D Mueller, J Mueller, K Mueller, V Mueller, P Naik, T Nakada, R Nandakumar, A Nandi, T Nanut, I Nasteva, M Needham, N Neri, S Neubert, N Neufeld, R Newcombe, TD Nguyen, C Nguyen-Mau, S Nieswand, R Niet, N Nikitin, A Nogay, NS Nolte, DP O'Hanlon, A Oblakowska-Mucha, V Obraztsov, R Oldeman, CJG Onderwater, A Ossowska, JM Otalora Goicochea, T Ovsiannikova, P Owen, A Oyanguren, PR Pais, T Pajero, A Palano, M Palutan, G Panshin, A Papanestis, M Pappagallo, LL Pappalardo, W Parker, C Parkes, G Passaleva, A Pastore, M Patel, C Patrignani, A Pearce, A Pellegrino, G Penso, M Pepe Altarelli, S Perazzini, D Pereima, P Perret, L Pescatore, K Petridis, A Petrolini, A Petrov, S Petrucci, M Petruzzo, B Pietrzyk, G Pietrzyk, M Pikies, M Pili, D Pinci, J Pinzino, F Pisani, A Piucci, V Placinta, S Playfer, J Plews, M Plo Casasus, F Polci, M Poli Lener, A Poluektov, N Polukhina, I Polyakov, E Polycarpo, GJ Pomery, S Ponce, A Popov, D Popov, S Poslavskii, E Price, J Prisciandaro, C Prouve, V Pugatch, A Puig Navarro, H Pullen, G Punzi, W Qian, J Qin, R Quagliani, B Quintana, NV Raab, B Rachwal, JH Rademacker, M Rama, M Ramos Pernas, MS Rangel, F Ratnikov, G Raven, M Ravonel Salzgeber, M Reboud, F Redi, S Reichert, AC dos Reis, F Reiss, C Remon Alepuz, Z Ren, V Renaudin, S Ricciardi, S Richards, K Rinnert, P Robbe, A Robert, AB Rodrigues, E Rodrigues, JA Rodriguez Lopez, M Roehrken, S Roiser, A Rollings, V Romanovskiy, A Romero Vidal, M Rotondo, MS Rudolph, T Ruf, J Ruiz Vidal, JJ Saborido Silva, N Sagidova, B Saitta, V Salustino Guimaraes, C Sanchez Gras, C Sanchez Mayordomo, B Sanmartin Sedes, R Santacesaria, C Santamarina Rios, M Santimaria, E Santovetti, G Sarpis, A Sarti, C Satriano, A Satta, M Saur, D Savrina, S Schael, M Schellenberg, M Schiller, H Schindler, M Schmelling, T Schmelzer, B Schmidt, O Schneider, A Schopper, HF Schreiner, M Schubiger, S Schulte, MH Schune, R Schwemmer, B Sciascia, A Sciubba, A Semennikov, ES Sepulveda, A Sergi, N Serra, J Serrano, L Sestini, A Seuthe, P Seyfert, M Shapkin, Y Shcheglov, T Shears, L Shekhtman, V Shevchenko, E Shmanin, BG Siddi, R Silva Coutinho, L Silva de Oliveira, G Simi, S Simone, I Skiba, N Skidmore, T Skwarnicki, MW Slater, JG Smeaton, E Smith, IT Smith, M Smith, M Soares, L Soares Lavra, MD Sokoloff, FJP Soler, B Souza De Paula, B Spaan, E Spadaro Norella, P Spradlin, F Stagni, M Stahl, S Stahl, P Stefko, S Stefkova, O Steinkamp, S Stemmle, O Stenyakin, M Stepanova, H Stevens, A Stocchi, S Stone, B Storaci, S Stracka, ME Stramaglia, M Straticiuc, U Straumann, S Strokov, J Sun, L Sun, Y Sun, K Swientek, A Szabelski, T Szumlak, M Szymanski, S T'Jampens, Z Tang, A Tayduganov, T Tekampe, G Tellarini, F Teubert, E Thomas, J van Tilburg, MJ Tilley, V Tisserand, M Tobin, S Tolk, L Tomassetti, D Tonelli, DY Tou, R Tourinho Jadallah Aoude, E Tournefier, M Traill, MT Tran, A Trisovic, A Tsaregorodtsev, G Tuci, A Tully, N Tuning, A Ukleja, A Usachov, A Ustyuzhanin, U Uwer, A Vagner, V Vagnoni, A Valassi, S Valat, G Valenti, R Vazquez Gomez, P Vazquez Regueiro, S Vecchi, M van Veghel, JJ Velthuis, M Veltri, G Veneziano, A Venkateswaran, M Vernet, M Veronesi, M Vesterinen, JV Viana Barbosa, D Vieira, M Vieites Diaz, H Viemann, X Vilasis-Cardona, A Vitkovskiy, M Vitti, V Volkov, A Vollhardt, D Vom Bruch, B Voneki, A Vorobyev, V Vorobyev, N Voropaev, JA de Vries, C Vazquez Sierra, R Waldi, J Walsh, J Wang, M Wang, Y Wang, Z Wang, DR Ward, HM Wark, NK Watson, D Websdale, A Weiden, C Weisser, M Whitehead, G Wilkinson, M Wilkinson, I Williams, MRJ Williams, M Williams, T Williams, FF Wilson, M Winn, W Wislicki, M Witek, G Wormser, SA Wotton, K Wyllie, D Xiao, Y Xie, A Xu, M Xu, Q Xu, Z Xu, Z Xu, Z Yang, Z Yang, Y Yao, LE Yeomans, H Yin, J Yu, X Yuan, O Yushchenko, KA Zarebski, M Zavertyaev, D Zhang, L Zhang, WC Zhang, Y Zhang, A Zhelezov, Y Zheng, X Zhu, V Zhukov, JB Zonneveld, S Zucchelli
Sep 03, 2021
The Cabibbo-suppressed decay $\Lambda_b^0\rightarrow\chi_{c1}p\pi^-$ is
observed for the first time using data from proton-proton collisions
corresponding to an integrated luminosity of 6fb$^{-1}$, collected with the
LHCb...
Performance Characteristics of Discrete-Time Queue With Variant Working Vacations
This article analyzes an infinite buffer discrete-time single server queueing system with variant working vacations in which customers arrive according to a geometric process. As soon as the system becomes empty, the server...
Published by: IGI Global Scientific Publishing
Biopharmaceutical aspects and implications of excipient variability in drug product performance
Implementation of Quality by Design approaches in pharmaceutical industry requires a sound understanding of the parameters triggering final product variability. Excipients, although generally regarded as inert components, are of...
The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells
Heather P Harding, Adriana Ordonez, Felicity Allen, Leopold Parts, Alison J Inglis, Roger L Williams, David Ron
Dec 19, 2019
The eukaryotic translation initiation factor 2α (eIF2α) kinase GCN2 is activated by amino acid starvation to elicit a rectifying physiological program known as the Integrated Stress Response (ISR). A role for uncharged tRNAs as...
A Potent View on the Effects of E-Learning
Due to the pandemic, there has been a drastic change in the advancement of online learning platforms. This article will help us understand the reasons for the increase and decrease of using online learning platforms. Based on...
Published by: IGI Global Scientific Publishing
Detailed structural analysis of amorphous Pd<sub>40</sub>Cu<sub>40</sub>P<sub>20</sub>
Shinya Hosokawa, Jean François Bérar, Nathalie Boudet, Wolf Christian Pilgrim, László Pusztai, Satoshi Hiroi, Shinji Kohara, Hidemi Kato, Henry E. Fischer, Anita Zeidler
Mar 01, 2021
To clarify the relationship between the glass-forming ability (GFA) and local atomic structure of Pd-based metallic glasses, the structures of an amorphous Pd40Cu40P20 (PCP) were investigated...
Anomalous X-ray scattering Glass-forming ability Hyper-ordered structures metallic glasses neutron diffraction Reverse Monte Carlo modeling /dk/atira/pure/subjectarea/asjc/2500/2504 name=Electronic, Optical and Magnetic Materials /dk/atira/pure/subjectarea/asjc/2500/2503 name=Ceramics and Composites /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry
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