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G-Force PD

Roger A Barker, Lorenz Studer, Elena Cattaneo, Jun Takahashi, G-Force PD consortium

Aug 20, 2015

G-Force PD consortium

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G-Quadruplexes

Chun Kit Kwok, Catherine J Merrick

Mar 18, 2019

Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention...

G-quadruplex aptamer biosensing cell imaging next-generation sequencing nucleic acid structure Animals Biomedical Research Biosensing Techniques G-Quadruplexes Humans

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Synthesis of Novel Regenerable 13X Zeolite-Polyimide Adsorbent Foams

Ramya G, Barry Crittenden, Martin Smith, Olivier Camus, Yong-Min Chew, Semali Perera

Apr 01, 2019

A new generic synthesis method is presented for the production of a polyimide (PI)/adsorbent (80 wt% 13X zeolite) regenerable foam filter. The method uses a dual parallel reaction foaming process comprising CO ₂...

Adsorbent foam Adsorption Air Filters Isotherms modelling Polyimide /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering /dk/atira/pure/subjectarea/asjc/2200/2209 name=Industrial and Manufacturing Engineering

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Synthesis of Novel Regenerable 13X Zeolite-Polyimide Adsorbent Foams

Ramya G, Barry Crittenden, Martin Smith, Olivier Camus, Yong-Min Chew, Semali Perera

Apr 01, 2019

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Remote stereocontrol in [3,3]-sigmatropic rearrangements

Nathan W G Fairhurst, Mary F Mahon, R H Munday, David R Carbery

Feb 03, 2012

The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...

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Bubbling solutions for Moser-Trudinger type equations on compact Riemann surfaces

Pablo Figueroa, Monica Musso

Nov 15, 2018

We study an elliptic equation related to the Moser–Trudinger inequality on a compact Riemann surface (S,g), Δ _gu+λ(ue ^{u ²}−[Formula presented]∫Sue ^{u ²}dv...

Green's function Moser–Trudinger inequality /dk/atira/pure/subjectarea/asjc/2600/2603 name=Analysis

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Bubbling solutions for Moser-Trudinger type equations on compact Riemann surfaces

Pablo Figueroa, Monica Musso

Nov 15, 2018

We study an elliptic equation related to the Moser–Trudinger inequality on a compact Riemann surface (S,g), Δ _gu+λ(ue ^{u ²}−[Formula presented]∫Sue ^{u ²}dv...

Green's function Moser–Trudinger inequality /dk/atira/pure/subjectarea/asjc/2600/2603 name=Analysis

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RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia.

Gregory G Fuller, Ting Han, Mallory A Freeberg, James J Moresco, Amirhossein Ghanbari Niaki, Nathan P Roach, John R Yates, Sua Myong, John K Kim

Apr 17, 2020

In hypoxic stress conditions, glycolysis enzymes assemble into singular cytoplasmic granules called glycolytic (G) bodies. G body formation in yeast correlates with increased glucose consumption and cell survival. However, the...

RNA S. cerevisiae Cell Biology Glycolysis Hypoxia phase separation Cytoplasmic Granules Endoribonucleases Glycolysis RNA Fungal Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins

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Associations between exposure to takeaway food outlets, takeaway food consumption, and body weight in Cambridgeshire, UK

Thomas Burgoine, Nita G Forouhi, Simon J Griffin, Nicholas J Wareham, Pablo Monsivais

Nov 05, 2018

OBJECTIVES: To examine the association between environmental exposure to takeaway food outlets, takeaway food consumption, and body weight, while accounting for home, work place, and commuting route environments. DESIGN...

Adult Body Weight Cross-Sectional Studies Diet Eating England Fast Foods Female Humans Linear Models Male Middle Aged obesity Transportation workplace

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Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor.

LJ Bridge, J Mead, E Frattini, I Winfield, G Ladds

Mar 16, 2018

Theoretical models of G protein-coupled receptor (GPCR) concentration-response relationships often assume an agonist producing a single functional response via a single active state of the receptor. These models have largely...

Biased signalling G protein-coupled receptors Mathematical pharmacology ordinary differential equations Receptor theory Algorithms Animals GTP-Binding Proteins Humans Ligands Models Biological Receptors G-Protein-Coupled Signal Transduction

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Remote stereocontrol in [3,3]-sigmatropic rearrangements

Nathan W G Fairhurst, Mary F Mahon, R H Munday, David R Carbery

Feb 03, 2012

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Groups satisfying a strong complement property

Eloisa Detomi, Andrea Lucchini, Mariapia Moscatiello, Pablo Spiga, Gunnar Traustason

Oct 01, 2019

Let G=NH be a finite group where N is normal in G and H is a complement of N in G. For a given generating sequence (h1,…,hd) of H we say that (N,(h1,…,hd)) satisfies the strong complement property, if 〈h1 x1,…,hd xd〉 is a...

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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

Dora-Maria Rasadean, Bin Sheng, Jyotirmayee Dash, G. Dan Pantos

Jun 23, 2017

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

Circular dichroism DNA G-quadruplex naphthalenediimide structure–activity relationships /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry

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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

Dora-Maria Rasadean, Bin Sheng, Jyotirmayee Dash, G. Dan Pantos

Jun 23, 2017

Circular dichroism DNA G-quadruplex naphthalenediimide structure–activity relationships /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry

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Groups satisfying a strong complement property

Eloisa Detomi, Andrea Lucchini, Mariapia Moscatiello, Pablo Spiga, Gunnar Traustason

Oct 01, 2019

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Cover Image for A practical graphitic carbon nitride (g-C<sub>3</sub>N<sub>4</sub>)based fluorescence sensor for the competitive detection of trithiocyanuric acid and mercury ions

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A practical graphitic carbon nitride (g-C3N4)based fluorescence sensor for the competitive detection of trithiocyanuric acid and mercury ions

Meng Li, Bo Wang, Xufei An, Zhiyong Li, Hongtao Zhu, Boyang Mao, David G. Calatayud, Tony D. James

Nov 01, 2019

A fluorescent sensor for the detection of trithiocyanuric acid (TCA)and Hg²⁺ was developed based on competitive interactions: non-covalent stacking between g-C₃N₄ and TCA vs coordinative...

Dye sensor Fluorescent sensor functional materials graphitic carbon nitride Mercury sensing /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering /dk/atira/pure/subjectarea/asjc/1500/1508 name=Process Chemistry and Technology

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A practical graphitic carbon nitride (g-C3N4)based fluorescence sensor for the competitive detection of trithiocyanuric acid and mercury ions

Meng Li, Bo Wang, Xufei An, Zhiyong Li, Hongtao Zhu, Boyang Mao, David G. Calatayud, Tony D. James

Nov 01, 2019

A fluorescent sensor for the detection of trithiocyanuric acid (TCA)and Hg²⁺ was developed based on competitive interactions: non-covalent stacking between g-C₃N₄ and TCA vs coordinative...

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Estimation of Poisson’s Ratio and Variation of Tensile Yield Strength of Composite Clay Balls Used in Pebble Matrix Filtration

J Rajapakse, C Gallage, Biyanvilage G, G Madabhushi, RA Fenner

Apr 25, 2017

composite clay balls Poisson ratio particle image velocimetry tensile yield strength pebble matrix filtration filter media

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Plasmodium falciparum GBP2 Is a Telomere-Associated Protein That Binds to G-Quadruplex DNA and RNA

James Edwards-Smallbone, Anders L Jensen, Lydia E Roberts, Francis Isidore G Totañes, Sarah R Hart, Catherine J Merrick

Mar 08, 2022

In the early-diverging protozoan parasite Plasmodium, few telomere-binding proteins have been identified and several are unique. Plasmodium telomeres, like those of...

Cellular and Infection Microbiology Plasmodium Malaria G-quadruplex Telomere proteomics of isolated chromatin fragments GBP2

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Fungal G-protein-coupled receptors:

Neil Brown, Sanne Schrevens, Patrick van Dijck, Gustavo Goldman

Apr 01, 2018

G-protein signalling pathways are involved in sensing the environment, enabling fungi to coordinate cell function, metabolism and development with their surroundings, thereby promoting their survival, propagation and virulence....

/dk/atira/pure/subjectarea/asjc/2400/2404 name=Microbiology /dk/atira/pure/subjectarea/asjc/2400/2403 name=Immunology /dk/atira/pure/subjectarea/asjc/2400/2402 name=Applied Microbiology and Biotechnology /dk/atira/pure/subjectarea/asjc/1300/1311 name=Genetics /dk/atira/pure/subjectarea/asjc/2700/2726 name=Microbiology (medical) /dk/atira/pure/subjectarea/asjc/1300/1307 name=Cell Biology /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being

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Fungal G-protein-coupled receptors:

Neil Brown, Sanne Schrevens, Patrick van Dijck, Gustavo Goldman

Apr 01, 2018

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Cover Image for A novel G protein-biased agonist at the μ opioid receptor induces substantial receptor desensitisation through G protein-coupled receptor kinase

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A novel G protein-biased agonist at the μ opioid receptor induces substantial receptor desensitisation through G protein-coupled receptor kinase

Sam Groom, Nina K Blum, Alexandra E Conibear, Alexander Disney, Rob Hill, Stephen M Husbands, Yangmei Li, Lawrence Toll, Andrea Kliewer, Stefan Schulz, Graeme Henderson, Eamonn Kelly, Chris P Bailey

Apr 30, 2023

Background and Purpose: G protein-biased μ opioid receptor agonists have the potential to induce less receptor desensitisation and tolerance than balanced opioids. Here, we investigated if the cyclic endomorphin analogue...

G protein-coupled receptor kinases Arrestins Biased agonism Electrophysiology opiates opioids receptor desensitisation /dk/atira/pure/subjectarea/asjc/3000/3004 name=Pharmacology

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Receptor Quaternary Organization Explains G Protein-Coupled Receptor Family Structure.

James H Felce, Sarah L Latty, Rachel G Knox, Susan R Mattick, Yuan Lui, Steven F Lee, David Klenerman, Simon J Davis

May 10, 2018

The organization of Rhodopsin-family G protein-coupled receptors (GPCRs) at the cell surface is controversial. Support both for and against the existence of dimers has been obtained in studies of mostly individual receptors....

BRET G protein-coupled receptors evolution single-molecule imaging stoichiometry Fluorescence Resonance Energy Transfer HEK293 Cells Humans Protein Multimerization Protein Structure Quaternary Protein Structure Secondary Receptors G-Protein-Coupled Rhodopsin

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Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36.

Michael C Chen, Ramreddy Tippana, Natalia A Demeshkina, Pierre Murat, Shankar Balasubramanian, Sua Myong, Adrian R Ferré-D'Amaré

Aug 03, 2018

Guanine-rich nucleic acid sequences challenge the replication, transcription, and translation machinery by spontaneously folding into G-quadruplexes, the unfolding of which requires forces greater than most polymerases can...

Amino Acid Motifs Animals Cattle Crystallography X-Ray DEAD-box RNA Helicases DNA Fluorescence Resonance Energy Transfer G-Quadruplexes Models Molecular Mutation Nucleic Acid Denaturation

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G-quadruplexes in pathogens

Lynne M Harris, Catherine J Merrick

Mar 18, 2019

DNA can form several secondary structures besides the classic double helix: one that has received much attention in recent years is the G-quadruplex (G4). This is a stable four-stranded structure formed by the stacking of...

Bacteria G-Quadruplexes Humans Virulence viruses

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