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Patrick Dougherty Project Continues with New Gallery Exhibitions in March
Winthrop University
Jan 01, 0001
"Patrick Dougherty: Stick Work," a series of photographs of Dougherty's past installations, will run March 31-May 7 at Gallery Up in Rock Hill. Opening March 26, an exhibition of the works of N.C. painter Jeremiah Miller will...
Published by: Winthrop University
Winthrop Alumnus Steven Patrick Awarded NCAA Postgraduate Scholarship
Winthrop University
Jan 01, 0001
Patrick, a native of Knoxville, Tennessee, will use the $7,500 award to attend medical school at Western University of Health Sciences of Osteopathic Medicine of the Pacific in Pomona, California. He was a recipient last year of...
Published by: Winthrop University
G-Quadruplexes
Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention...
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Incarnate Quested Speaking
Patrick Brown
Jun 23, 2022
Patrick Brown is an independent scholar in Honolulu, Hawaii. Before moving to Hawaii, he taught in the philosophy department and the school of law at Seattle University. Brown received his Ph.D. in philosophy from Boston...
Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
Published by:
Incarnate Quested Speaking
Patrick Brown
Jun 23, 2022
Patrick Brown is an independent scholar in Honolulu, Hawaii. Before moving to Hawaii, he taught in the philosophy department and the school of law at Seattle University. Brown received his Ph.D. in philosophy from Boston...
RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia.
In hypoxic stress conditions, glycolysis enzymes assemble into singular cytoplasmic granules called glycolytic (G) bodies. G body formation in yeast correlates with increased glucose consumption and cell survival. However, the...
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Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
Published by:
Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor.
Theoretical models of G protein-coupled receptor (GPCR) concentration-response relationships often assume an agonist producing a single functional response via a single active state of the receptor. These models have largely...
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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

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