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Assessing the measurement invariance and antecedents of legal cynicism in São Paulo, Zurich, and Montevideo.
INTRODUCTION: This paper accomplishes two goals. First, we assesses the measurement invariance of legal cynicism among adolescents in São Paulo, Brazil, Montevideo, Uruguay, and Zurich, Switzerland. Second, we evaluate a series...
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Health impact modelling of different travel patterns on physical activity, air pollution and road injuries for São Paulo, Brazil.
BACKGROUND: São Paulo city, Brazil, faces challenges caused by rapid urbanization. We illustrate how future travel patterns could lead to different health consequences in the city. METHODS: We evaluated the health impacts of...
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G-Quadruplexes
Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention...
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Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
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The role of social support in reducing the impact of violence on adolescents’ mental health in São Paulo, Brazil
Objectives: We investigated whether perceived social support among adolescent students moderated the association between violence exposure and internalising symptoms in São Paulo city, Brazil. Methods: We tested the...
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RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia.
In hypoxic stress conditions, glycolysis enzymes assemble into singular cytoplasmic granules called glycolytic (G) bodies. G body formation in yeast correlates with increased glucose consumption and cell survival. However, the...
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Remote stereocontrol in [3,3]-sigmatropic rearrangements
The Ireland - Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is highly stereoselective and offers excellent levels of remote...
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Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor.
Theoretical models of G protein-coupled receptor (GPCR) concentration-response relationships often assume an agonist producing a single functional response via a single active state of the receptor. These models have largely...
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Judging Beyond the Sandal
Peter Candy
Jun 22, 2020
D.19.2.31 (Alf. 5 dig. a Paulo epit.) is a remarkable text that has eluded interpretation for centuries. This exegesis shows how taking account of the text’s logical and rhetorical features facilitates its interpretation from a...
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Special issue "reflecting on Freire: a praxis of radical love and critical hope for science education"-theme: transnational collaborations and solidarities: Transnational conversations about science education
Haira Gandolfi
Mar 27, 2023
In this article I will examine some of the issues raised by the following three articles in this special issue about Paulo Freire and science education: Jenny Tilsen's "The freshness of irreverence": learning from ACT UP towards...
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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

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Amino-Acid-Derived Naphthalenediimides as Versatile G-Quadruplex Binders

The design and synthesis of water soluble, amino-acid-functionalised naphthalenediimides (NDIs) as potential ligands of native G-quadruplexes is reported. The NDIs were tested on a panel of oncogene promoters, on the human...

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The CHEK2 Variant C.349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor.
The identification of recurrent founder variants in cancer predisposing genes may have important implications for implementing cost-effective targeted genetic screening strategies. In this study, we evaluated the prevalence and...
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Behavior disorders and subjective burden among caregivers of demented patients.
UNLABELLED: Many patients with dementia live within the community supported by their family and friends. Majority of patient caregivers suffer from high levels of stress. METHODS: A quasi-experimental study, which compared the...
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