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Structure-Guided Computational Approaches to Unravel Druggable Proteomic Landscape of Mycobacterium leprae.
Leprosy, caused by Mycobacterium leprae (M. leprae), is treated with a multidrug regimen comprising Dapsone, Rifampicin, and Clofazimine. These drugs exhibit bacteriostatic, bactericidal and anti-inflammatory properties...
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The Molecular Organization of Human cGMP Specific Phosphodiesterase 6 (PDE6)
In the cyclic guanosine monophosphate (cGMP) signaling pathway, phosphodiesterase 6 (PDE6) maintains a critical balance of the intracellular concentration of cGMP by catalyzing it to 5' guanosine monophosphate (5'-GMP). To gain...
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Spanish Professor Selected as Thompson Scholar
Winthrop University
Jan 01, 0001
Spanish professor Pedro Muñoz has been chosen as the new Thompson Scholar. Muñoz, a native of Spain, will spend a year researching service learning courses for at-risk Hispanic students.
Published by: Winthrop University
Holism as the empirical significance of symmetries
Henrique Gomes
Sep 28, 2021
AbstractNot all symmetries are on a par. For instance, within Newtonian mechanics, we seem to have a good grasp on the empirical significance of boosts, by applying it to subsystems. This is...
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Holism as the empirical significance of symmetries
Henrique Gomes
Aug 13, 2021
Abstract: Not all symmetries are on a par. For instance, within Newtonian mechanics, we seem to have a good grasp on the empirical significance of boosts, by applying it to subsystems. This is exemplified by the thought...
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Access to long-term credit and productivity of small and medium firms
This letter assesses the impact of a variation in access to a targeted loan program from Brazil’s development bank on investment and productivity. Results suggest that eligible firms increased their relative investment rate and...
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Behavior disorders and subjective burden among caregivers of demented patients.
UNLABELLED: Many patients with dementia live within the community supported by their family and friends. Majority of patient caregivers suffer from high levels of stress. METHODS: A quasi-experimental study, which compared the...
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A Josephson relation for fractionally charged anyons.
Anyons occur in two-dimensional electron systems as excitations with fractional charge in the topologically ordered states of the fractional quantum Hall effect (FQHE). Their dynamics are of utmost importance for topological...
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Analysis of word number and content in discourse of patients with mild to moderate Alzheimer's disease.
UNLABELLED: Alzheimer's disease (AD) is characterized by impairments in memory and other cognitive functions such as language, which can be affected in all aspects including discourse. A picture description task is considered an...
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The Effect of Coercive Digitization on Organizational Performance
This article investigates the influence of institutional pressure on digitalization and performance, exploring the role of consulting companies in their relationships. The study is based on empirical findings administered to 600...

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