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Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells.
Mohamed-Sami Trabelsi, Mehdi Daoudi, Janne Prawitt, Sarah Ducastel, Véronique Touche, Sama I Sayin, Alessia Perino, Cheryl A Brighton, Yasmine Sebti, Jérôme Kluza, Olivier Briand, Hélène Dehondt, Emmanuelle Vallez, Emilie Dorchies, Grégory Baud, Valeria Spinelli, Nathalie Hennuyer, Sandrine Caron, Kadiombo Bantubungi, Robert Caiazzo, Frank Reimann, Philippe Marchetti, Philippe Lefebvre, Fredrik Bäckhed, Fiona M Gribble, Kristina Schoonjans, François Pattou, Anne Tailleux, Bart Staels, Sophie Lestavel
Jan 31, 2020
Bile acids are signalling molecules, which activate the transmembrane receptor TGR5 and the nuclear receptor FXR. BA sequestrants (BAS) complex bile acids in the intestinal lumen and decrease intestinal FXR activity. The BAS-BA...
Animals Anticholesteremic Agents Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Bile Acids and Salts Blood Glucose Colesevelam Hydrochloride Colon Diet High-Fat Enteroendocrine Cells Glucagon-Like Peptide 1 Glycolysis Humans Ileum Insulin Insulin Secretion Insulin-Secreting Cells Intestinal Mucosa Intestines Jejunum Mice Mice Knockout Mice Obese Nuclear Proteins obesity Proglucagon RNA Messenger Receptors Cytoplasmic and Nuclear Receptors G-Protein-Coupled Sequestering Agents Signal Transduction Transcription Factors
Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
Eugene L. Opie, 1910
The Rockefeller University
Jan 01, 0001
Eugene L. Opie, M.D. Inflammation
Lecture delivered February 10th, 1910
Bacterial Infection inflammation reaction macrophage Lymphatic Vessels polynuclear leucocytes enzyme
Published by: J.B. Lippincott Company
Floer Simple Manifolds and L-Space Intervals
An oriented three-manifold with torus boundary admits either no L-space Dehn filling, a unique L-space filling, or an interval of L-space fillings. In the latter case, which we call “Floer simple,” we construct an invariant...
Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof
This work aimed to (a) characterize the microstructure and porosity of human nail and bovine hoof by mercury intrusion porosimetry and SEM image analysis, (b) study the effects of hydration and of N-acetyl-l-cysteine treatment...
The Lantern Vol. 2, No. 2, March 1934
Rose-Marie Brubaker, Joyce L. Strickland, Ruth I. Hamma, Anna May Brooks, Keturah R. Donalson, Nadine Jones, Sara E. Brown, Dorothy Witmer, Virginia A. Meyer
Jan 01, 0001
Fulfillment Through Expression Ole Man Ennis Nos Illusions by Philippe Vallee A Celtic May Day Festival Dew Drops Baker Street Fiction March Winds Winter Sunset Book Review: No Second Spring A Thought The...
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
L q -spectra of self-affine measures
Abstract: We study L q -spectra of planar self-affine measures generated by diagonal matrices. We introduce a new technique for constructing and understanding examples based on combinatorial estimates for the exponential growth...
Corinna PMG 655 (= P.Oxy. 2370) fr.1 l. 13 κόσμ[εισα λόγυ]ς
L Prauscello
May 02, 2017
0. Fr. 1 of P.Oxy. 2370 (= MP3
249; LDAB 573), published by Lobel in 1956, is so far the only papyrus
fragment among those extant in Boeotian dialect1
whose authorship can be securely ascribed to
Corinna thanks to the overlap...
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
Frank L. Horsfall, Jr., 1952
The Rockefeller University
Jan 01, 0001
Frank L. Horsfall, Jr. Experiments on chemical alteration of virus infections.
Lecture delivered November 20, 1952
Posted with permission
Published by: Academic Press Inc., Publishers
Rapid sensing of l-leucine by human and murine hypothalamic neurons
Nicholas Heeley, Peter Kirwan, Tamana Darwish, Marion Arnaud, Mark L Evans, Florian T Merkle, Frank Reimann, Fiona M Gribble, Clemence Blouet
Apr 05, 2018
OBJECTIVE: Dietary proteins are sensed by hypothalamic neurons and strongly influence multiple aspects of metabolic health, including appetite, weight gain, and adiposity. However, little is known about the mechanisms by which...
S-2-Amino-4-cyanobutanoic acid (β-cyanomethyl-L-Ala) as an atom-efficient solubilising synthon for L-glutamine
Glutamine (Gln) is often a difficult amino acid to incorporate during solution-phase peptide synthesis, owing to poor solubility and unwanted dehydrations as side-reactions. Current approaches to solving these problems are...
Microbial regulation of the L cell transcriptome.
Tulika Arora, Rozita Akrami, Ramona Pais, Linda Bergqvist, Bengt R Johansson, Thue W Schwartz, Frank Reimann, Fiona M Gribble, Fredrik Bäckhed
Apr 26, 2018
L cells are an important class of enteroendocrine cells secreting hormones such as glucagon like peptide-1 and peptide YY that have several metabolic and physiological effects. The gut is home to trillions of bacteria affecting...
Dr. Herman L. Frick Promotion
Winthrop News Service
Jan 01, 0001
Dr. Herman L. Frick, superintendent of Winthrop Training School, was named Director of Teacher Education and Graduate Study at Winthrop in October 1946 Dr. Frick worked at Winthrop from 1941 to 1949 except for 1944-1946 when he...
Winthrop College of Education Winthrop Training School Higher Education Teacher Education and Professional Development
Published by: Winthrop University
Influence of soft ferromagnetic sections on the magnetic flux density profile of a large grain, bulk Y-Ba-Cu-O superconductor
MP Philippe, MD Ainslie, L Wéra, JF Fagnard, AR Dennis, YH Shi, DA Cardwell, B Vanderheyden, P Vanderbemden
Jul 14, 2015
L(3)mbt and the LINT complex safeguard cellular identity in the Drosophila ovary.
Maintenance of cellular identity is essential for tissue development and homeostasis. At the molecular level, cell identity is determined by the coordinated activation and repression of defined sets of genes. The tumor...
L<sup>q</sup>-spectra of self-affine measures
Abstract
We study L
q
-spectra of planar...
Glucose control upon waking is unaffected by hourly sleep fragmentation during the night, but is impaired by morning caffeinated coffee
Harry A. Smith, Aaron Hengist, Joel Thomas, Jean Philippe Walhin, Philippa Heath, Oliver Perkin, Yung Chih Chen, Javier T. Gonzalez, James A. Betts
Nov 28, 2020
Morning coffee is a common remedy following disrupted sleep, yet each factor can independently impair glucose tolerance and insulin sensitivity in healthy adults. Remarkably, the combined effects of sleep fragmentation and...
L<sup>q</sup>-spectra of self-affine measures
Abstract
We study L
q
-spectra of planar...
Second-Order <i>L</i> ∞ Variational Problems and the ∞-Polylaplacian
In this paper we initiate the study of second-order variational problems in L ∞, seeking to minimise the L ∞ norm of a function of the hessian.We also derive and study the respective PDE arising as the...
Computation Provides Chemical Insight into the Diverse Hydride NMR Chemical Shifts of [Ru(NHC)<sub>4</sub>(L)H]<sup>0/+</sup> Species (NHC = N-heterocyclic carbene; L = vacant, H<sub>2</sub>, N<sub>2</sub>, CO, MeCN, O<sub>2</sub>, P<sub>4</sub>, SO<sub>2</sub>, H<sup>-</sup>, F<sup>-</sup> and Cl<sup>-</sup>) and their [Ru(R<sub>2</sub>PCH<sub>2</sub>CH<sub>2</sub>PR<sub>2</sub>)<sub>2</sub>(L)H]<sup>+</sup> Congeners
L J L Haller, Elena Mas-Marza, Mateusz K Cybulski, Rajashekharayya A Sanguramath, Stuart A Macgregor, Mary F Mahon, Christophe Raynaud, Christopher A Russell, Michael K Whittlesey
Mar 07, 2017
Relativistic density functional theory calculations, both with and without the effects of spin–orbit coupling, have been employed to model hydride NMR chemical shifts for a series of [Ru(NHC)4(L)H]0/+ species (NHC =...
Computation Provides Chemical Insight into the Diverse Hydride NMR Chemical Shifts of [Ru(NHC)<sub>4</sub>(L)H]<sup>0/+</sup> Species (NHC = N-heterocyclic carbene; L = vacant, H<sub>2</sub>, N<sub>2</sub>, CO, MeCN, O<sub>2</sub>, P<sub>4</sub>, SO<sub>2</sub>, H<sup>-</sup>, F<sup>-</sup> and Cl<sup>-</sup>) and their [Ru(R<sub>2</sub>PCH<sub>2</sub>CH<sub>2</sub>PR<sub>2</sub>)<sub>2</sub>(L)H]<sup>+</sup> Congeners
L J L Haller, Elena Mas-Marza, Mateusz K Cybulski, Rajashekharayya A Sanguramath, Stuart A Macgregor, Mary F Mahon, Christophe Raynaud, Christopher A Russell, Michael K Whittlesey
Mar 07, 2017
Relativistic density functional theory calculations, both with and without the effects of spin–orbit coupling, have been employed to model hydride NMR chemical shifts for a series of [Ru(NHC)4(L)H]0/+ species (NHC =...
L-carnitine, a friend or foe for cardiovascular disease? A Mendelian randomization study.
BACKGROUND: L-carnitine is emerging as an item of interest for cardiovascular disease (CVD) prevention and treatment, but controversy exists. To examine the effectiveness and safety of L-carnitine, we assessed how genetically...
l-carnitine, a friend or foe for cardiovascular disease? A Mendelian randomization study
Abstract
Background
l -carnitine is emerging as an item of interest for cardiovascular disease (CVD)...
Forecasting of Electricity Demand by Hybrid ANN-PSO Models
Developing economies need to invest in energy projects. Because the gestation period of the electric projects is high, it is of paramount importance to accurately forecast the energy requirements. In the present paper, the...
Published by: IGI Global Scientific Publishing
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