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Results: 23
Updating the Psoriatic Arthritis (PsA) core domain set
Ana-Maria Orbai, Maarten de Wit, Philip J Mease, Kristina Callis Duffin, Musaab Elmamoun, William Tillett, Willemina Campbell, Oliver FitzGerald, Dafna D Gladman, Niti Goel, Laure Gossec, Pil Hoejgaard, Ying Ying Leung, Chris Lindsay, Vibeke Strand, Désirée M van der Heijde, Bev Shea, Robin Christensen, Laura Coates, Lihi Eder, Neil McHugh, Umut Kalyoncu, Ingrid Steinkoenig, Alexis Ogdie
Oct 01, 2017
OBJECTIVE: To include the patient perspective in accordance with the Outcome Measures in Rheumatology (OMERACT) Filter 2.0 in the updated Psoriatic Arthritis (PsA) Core Domain Set for randomized controlled trials (RCT) and...
Group Contests with Internal Conflict and Power Asymmetry
We investigate simultaneous inter- and intra-group conflict in the shadow of within-group power asymmetry and complementarity in members' group-conflict efforts. A more symmetric group faces a higher degree of internal conflict...
A Consortium Blockchain-Enabled Evidence Sharing System for Public Interest Litigation
Procuratorates, as the prosecutor in public interest litigation (PIL), need to obtain evidence from other PIL stakeholders including citizens, companies, governmental agencies, IoT monitoring devices and so on. However, the...
Published by: IGI Global Scientific Publishing
Updating the Psoriatic Arthritis (PsA) core domain set
Ana-Maria Orbai, Maarten de Wit, Philip J Mease, Kristina Callis Duffin, Musaab Elmamoun, William Tillett, Willemina Campbell, Oliver FitzGerald, Dafna D Gladman, Niti Goel, Laure Gossec, Pil Hoejgaard, Ying Ying Leung, Chris Lindsay, Vibeke Strand, Désirée M van der Heijde, Bev Shea, Robin Christensen, Laura Coates, Lihi Eder, Neil McHugh, Umut Kalyoncu, Ingrid Steinkoenig, Alexis Ogdie
Oct 01, 2017
OBJECTIVE: To include the patient perspective in accordance with the Outcome Measures in Rheumatology (OMERACT) Filter 2.0 in the updated Psoriatic Arthritis (PsA) Core Domain Set for randomized controlled trials (RCT) and...
Group Contests with Internal Conflict and Power Asymmetry
We investigate simultaneous inter- and intra-group conflict in the shadow of within-group power asymmetry and complementarity in members' group-conflict efforts. A more symmetric group faces a higher degree of internal conflict...
Clinical trial discrimination of physical function instruments for psoriatic arthritis
Ying-Ying Leung, Richard Holland, Ashish J Mathew, Christine Lindsay, Niti Goel, Alexis Ogdie, Ana-Maria Orbai, Pil Hojgaard, Jeffrey Chau, Laura C Coates, Vibeke Strand, Dafna D Gladman, Robin Christensen, William Tillett, Philip Mease
Oct 01, 2020
OBJECTIVES: Physical function (PF) is a core domain to be measured in randomized controlled trials (RCTs) of psoriatic arthritis (PsA), yet the discriminative performance of patient reported outcome measures (PROMs) for PF in...
Appraisal of candidate instruments for assessment of the physical function domain in patients with psoriatic arthritis
Ying Ying Leung, Ana Maria Orbai, Alexis Ogdie, Pil Hojgaard, Richard Holland, Niti Goel, Jeffrey Chau, Laura C. Coates, Vibeke Strand, Dafna D. Gladman, Philip J. Mease, Robin Christensen, William Tillett
Jan 01, 2021
Objective. Numerous patient-reported outcome measures (PROM) exist for the measurement of physical function for psoriatic arthritis (PsA), but only a few are validated comprehensively. The objective of this project was to...
Clinical trial discrimination of physical function instruments for psoriatic arthritis
Ying-Ying Leung, Richard Holland, Ashish J Mathew, Christine Lindsay, Niti Goel, Alexis Ogdie, Ana-Maria Orbai, Pil Hojgaard, Jeffrey Chau, Laura C Coates, Vibeke Strand, Dafna D Gladman, Robin Christensen, William Tillett, Philip Mease
Oct 01, 2020
OBJECTIVES: Physical function (PF) is a core domain to be measured in randomized controlled trials (RCTs) of psoriatic arthritis (PsA), yet the discriminative performance of patient reported outcome measures (PROMs) for PF in...
OMERACT Filter 2.1 Instrument Selection for Physical Function Domain in Psoriatic Arthritis
Ying-Ying Leung, Ana-Maria Orbai, Pil Hojgaard, Richard Holland, Ashish J Mathew, Niti Goel, Jeffrey Chau, William Tillett, Christine Lindsay, Alexis Ogdie, Laura C Coates, Dafna D Gladman, Robin Christensen, Philip Mease, Vibeke Strand
Oct 01, 2021
OBJECTIVES: Physical function is one of the core domains to be measured in all trials in psoriatic arthritis (PsA). We aimed to evaluate two instruments for physical function in PsA: The Health Assessment...
Appraisal of candidate instruments for assessment of the physical function domain in patients with psoriatic arthritis
Ying Ying Leung, Ana Maria Orbai, Alexis Ogdie, Pil Hojgaard, Richard Holland, Niti Goel, Jeffrey Chau, Laura C. Coates, Vibeke Strand, Dafna D. Gladman, Philip J. Mease, Robin Christensen, William Tillett
Jan 01, 2021
Objective. Numerous patient-reported outcome measures (PROM) exist for the measurement of physical function for psoriatic arthritis (PsA), but only a few are validated comprehensively. The objective of this project was to...
Content and Face Validity and Feasibility of 5 Candidate Instruments for Psoriatic Arthritis Randomized Controlled Trials
Richard Holland, William Tillett, Alexis Ogdie, Ying Y Leung, Dafna D Gladman, Kristina Callis Duffin, Laura C Coates, Philip J Mease, Lihi Eder, Vibeke Strand, Musaab Elmamoun, Pil Højgaard, Jeffrey Chau, Maarten de Wit, Niti Goel, Chris A Lindsay, Oliver FitzGerald, Bev Shea, Dorcas Beaton, Ana-Maria Orbai
Jun 01, 2018
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-Outcome Measures in Rheumatology (OMERACT) Psoriatic Arthritis (PsA) Core Set working group is in the process of selecting core instruments...
PsAID12 Provisionally Endorsed at OMERACT 2018 as Core Outcome Measure to Assess Psoriatic Arthritis-specific Health-related Quality of Life in Clinical Trials
Ana-Maria Orbai, Richard Holland, Ying Ying Leung, William Tillett, Niti Goel, Robin Christensen, Neil McHugh, Laure Gossec, Maarten de Wit, Pil Højgaard, Laura C Coates, Philip J Mease, Julie Birt, Lara Fallon, Oliver FitzGerald, Alexis Ogdie, Beverly Shea, Vibeke Strand, Kristina Callis Duffin, Peter Tugwell, Dorcas Beaton, Dafna D Gladman
Aug 01, 2019
OBJECTIVE: The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) and Outcome Measures in Rheumatology (OMERACT) psoriatic arthritis (PsA) working group is developing a Core Outcome Measurement...
A systematic review of measurement properties of patient reported outcome measures in psoriatic arthritis
Pil Højgaard, Louise Klokker, Ana-Maria Orbai, Kim Holmsted, Else M Bartels, Ying Ying Leung, Niti Goel, Maarten de Wit, Dafna D Gladman, Philip J Mease, Lene Dreyer, Lars E Kristensen, Oliver FitzGerald, William Tillett, Laure Gossec, Philip Helliwell, Vibeke Strand, Alexis Ogdie, Caroline B Terwee, Robin Christensen
Apr 01, 2018
BACKGROUND: An updated psoriatic arthritis (PsA) core outcome set (COS) for randomized controlled trials (RCTs) was endorsed at the Outcome Measures in Rheumatology (OMERACT) meeting in 2016.
OBJECTIVES: To synthesize...
PsAID12 Provisionally Endorsed at OMERACT 2018 as Core Outcome Measure to Assess Psoriatic Arthritis-specific Health-related Quality of Life in Clinical Trials
Ana-Maria Orbai, Richard Holland, Ying Ying Leung, William Tillett, Niti Goel, Robin Christensen, Neil McHugh, Laure Gossec, Maarten de Wit, Pil Højgaard, Laura C Coates, Philip J Mease, Julie Birt, Lara Fallon, Oliver FitzGerald, Alexis Ogdie, Beverly Shea, Vibeke Strand, Kristina Callis Duffin, Peter Tugwell, Dorcas Beaton, Dafna D Gladman
Aug 01, 2019
OBJECTIVE: The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) and Outcome Measures in Rheumatology (OMERACT) psoriatic arthritis (PsA) working group is developing a Core Outcome Measurement...
OMERACT Filter 2.1 Instrument Selection for Physical Function Domain in Psoriatic Arthritis
Ying-Ying Leung, Ana-Maria Orbai, Pil Hojgaard, Richard Holland, Ashish J Mathew, Niti Goel, Jeffrey Chau, William Tillett, Christine Lindsay, Alexis Ogdie, Laura C Coates, Dafna D Gladman, Robin Christensen, Philip Mease, Vibeke Strand
Oct 01, 2021
OBJECTIVES: Physical function is one of the core domains to be measured in all trials in psoriatic arthritis (PsA). We aimed to evaluate two instruments for physical function in PsA: The Health Assessment...
Content and Face Validity and Feasibility of 5 Candidate Instruments for Psoriatic Arthritis Randomized Controlled Trials
Richard Holland, William Tillett, Alexis Ogdie, Ying Y Leung, Dafna D Gladman, Kristina Callis Duffin, Laura C Coates, Philip J Mease, Lihi Eder, Vibeke Strand, Musaab Elmamoun, Pil Højgaard, Jeffrey Chau, Maarten de Wit, Niti Goel, Chris A Lindsay, Oliver FitzGerald, Bev Shea, Dorcas Beaton, Ana-Maria Orbai
Jun 01, 2018
The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-Outcome Measures in Rheumatology (OMERACT) Psoriatic Arthritis (PsA) Core Set working group is in the process of selecting core instruments...
High-resolution label-free 3D mapping of extracellular pH of single living cells.
Yanjun Zhang, Yasufumi Takahashi, Sung Pil Hong, Fengjie Liu, Joanna Bednarska, Philip S Goff, Pavel Novak, Andrew Shevchuk, Sahana Gopal, Iros Barozzi, Luca Magnani, Hideki Sakai, Yoshimoto Suguru, Takuto Fujii, Alexander Erofeev, Peter Gorelkin, Alexander Majouga, Dominik J Weiss, Christopher Edwards, Aleksandar P Ivanov, David Klenerman, Elena V Sviderskaya, Joshua B Edel, Yuri Korchev
Feb 03, 2020
Dynamic mapping of extracellular pH (pHe) at the single-cell level is critical for understanding the role of H+ in cellular and subcellular processes, with particular importance in cancer. While several pHe sensing techniques...
A systematic review of measurement properties of patient reported outcome measures in psoriatic arthritis
Pil Højgaard, Louise Klokker, Ana-Maria Orbai, Kim Holmsted, Else M Bartels, Ying Ying Leung, Niti Goel, Maarten de Wit, Dafna D Gladman, Philip J Mease, Lene Dreyer, Lars E Kristensen, Oliver FitzGerald, William Tillett, Laure Gossec, Philip Helliwell, Vibeke Strand, Alexis Ogdie, Caroline B Terwee, Robin Christensen
Apr 01, 2018
BACKGROUND: An updated psoriatic arthritis (PsA) core outcome set (COS) for randomized controlled trials (RCTs) was endorsed at the Outcome Measures in Rheumatology (OMERACT) meeting in 2016.
OBJECTIVES: To synthesize...
ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism.
Tetsuro Murakami, Seung-Pil Yang, Lin Xie, Taizo Kawano, Donald Fu, Asuka Mukai, Christopher Bohm, Fusheng Chen, Janice Robertson, Hiroshi Suzuki, Gian Gaetano Tartaglia, Michele Vendruscolo, Gabriele S Kaminski Schierle, Fiona TS Chan, Aileen Moloney, Damian Crowther, Clemens F Kaminski, Mei Zhen, Peter St George-Hyslop
Feb 12, 2020
It is unclear whether mutations in fused in sarcoma (FUS) cause familial amyotrophic lateral sclerosis via a loss-of-function effect due to titrating FUS from the nucleus or a gain-of-function effect from cytoplasmic...
High-resolution label-free 3D mapping of extracellular pH of single living cells.
Yanjun Zhang, Yasufumi Takahashi, Sung Pil Hong, Fengjie Liu, Joanna Bednarska, Philip S Goff, Pavel Novak, Andrew Shevchuk, Sahana Gopal, Iros Barozzi, Luca Magnani, Hideki Sakai, Yoshimoto Suguru, Takuto Fujii, Alexander Erofeev, Peter Gorelkin, Alexander Majouga, Dominik J Weiss, Christopher Edwards, Aleksandar P Ivanov, David Klenerman, Elena V Sviderskaya, Joshua B Edel, Yuri Korchev
Jan 07, 2020
Dynamic mapping of extracellular pH (pHe) at the single-cell level is critical for understanding the role of H+ in cellular and subcellular processes, with particular importance in cancer. While several pHe sensing techniques...
High-resolution label-free 3D mapping of extracellular pH of single living cells
Yanjun Zhang, Yasufumi Takahashi, Sung Pil Hong, Fengjie Liu, Joanna Bednarska, Philip S. Goff, Pavel Novak, Andrew Shevchuk, Sahana Gopal, Iros Barozzi, Luca Magnani, Hideki Sakai, Yoshimoto Suguru, Takuto Fujii, Alexander Erofeev, Peter Gorelkin, Alexander Majouga, Dominik J. Weiss, Christopher Edwards, Aleksandar P. Ivanov, David Klenerman, Elena V. Sviderskaya, Joshua B. Edel, Yuri Korchev
Dec 05, 2020
Abstract: Dynamic mapping of extracellular pH (pHe) at the single-cell level is critical for understanding the role of H+ in cellular and subcellular processes, with particular importance in cancer. While several pHe sensing...
ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function.
Tetsuro Murakami, Seema Qamar, Julie Qiaojin Lin, Gabriele S Kaminski Schierle, Eric Rees, Akinori Miyashita, Ana R Costa, Roger B Dodd, Fiona TS Chan, Claire H Michel, Deborah Kronenberg-Versteeg, Yi Li, Seung-Pil Yang, Yosuke Wakutani, William Meadows, Rodylyn Rose Ferry, Liang Dong, Gian Gaetano Tartaglia, Giorgio Favrin, Wen-Lang Lin, Dennis W Dickson, Mei Zhen, David Ron, Gerold Schmitt-Ulms, Paul E Fraser, Neil A Shneider, Christine Holt, Michele Vendruscolo, Clemens F Kaminski, Peter St George-Hyslop
Oct 22, 2015
Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness.
Vivek L Patel, Evan L Busch, Tara M Friebel, Angel Cronin, Goska Leslie, Lesley McGuffog, Julian Adlard, Simona Agata, Bjarni A Agnarsson, Munaza Ahmed, Kristiina Aittomäki, Elisa Alducci, Irene L Andrulis, Adalgeir Arason, Norbert Arnold, Grazia Artioli, Brita Arver, Bernd Auber, Jacopo Azzollini, Judith Balmaña, Rosa B Barkardottir, Daniel R Barnes, Alicia Barroso, Daniel Barrowdale, Muriel Belotti, Javier Benitez, Birgitte Bertelsen, Marinus J Blok, Istvan Bodrogi, Valérie Bonadona, Bernardo Bonanni, Davide Bondavalli, Susanne E Boonen, Julika Borde, Ake Borg, Angela R Bradbury, Angela Brady, Carole Brewer, Joan Brunet, Bruno Buecher, Saundra S Buys, Santiago Cabezas-Camarero, Trinidad Caldés, Almuth Caliebe, Maria A Caligo, Mariarosaria Calvello, Ian G Campbell, Ileana Carnevali, Estela Carrasco, Tsun L Chan, Annie TW Chu, Wendy K Chung, Kathleen BM Claes, Gemo Study Collaborators, Embrace Collaborators, Jackie Cook, Laura Cortesi, Fergus J Couch, Mary B Daly, Giuseppe Damante, Esther Darder, Rosemarie Davidson, Miguel de la Hoya, Lara Della Puppa, Joe Dennis, Orland Díez, Yuan Chun Ding, Nina Ditsch, Susan M Domchek, Alan Donaldson, Bernd Dworniczak, Douglas F Easton, Diana M Eccles, Rosalind A Eeles, Hans Ehrencrona, Bent Ejlertsen, Christoph Engel, D Gareth Evans, Laurence Faivre, Ulrike Faust, Lídia Feliubadaló, Lenka Foretova, Florentia Fostira, George Fountzilas, Debra Frost, Vanesa García-Barberán, Pilar Garre, Marion Gauthier-Villars, Lajos Géczi, Andrea Gehrig, Anne-Marie Gerdes, Paul Gesta, Giuseppe Giannini, Gord Glendon, Andrew K Godwin, David E Goldgar, Mark H Greene, Angelica M Gutierrez-Barrera, Eric Hahnen, Ute Hamann, Jan Hauke, Natalie Herold, Frans BL Hogervorst, Ellen Honisch, John L Hopper, Peter J Hulick, KConFaB Investigators, Hebon Investigators, Louise Izatt, Agnes Jager, Paul James, Ramunas Janavicius, Uffe Birk Jensen, Thomas Dyrso Jensen, Oskar Th Johannsson, Esther M John, Vijai Joseph, Eunyoung Kang, Karin Kast, Johanna I Kiiski, Sung-Won Kim, Zisun Kim, Kwang-Pil Ko, Irene Konstantopoulou, Gero Kramer, Lotte Krogh, Torben A Kruse, Ava Kwong, Mirjam Larsen, Christine Lasset, Charlotte Lautrup, Conxi Lazaro, Jihyoun Lee, Jong Won Lee, Min Hyuk Lee, Johannes Lemke, Fabienne Lesueur, Annelie Liljegren, Annika Lindblom, Patricia Llovet, Adria Lopez-Fernández, Irene Lopez-Perolio, Victor Lorca, Jennifer T Loud, Edmond SK Ma, Phuong L Mai, Siranoush Manoukian, Veronique Mari, Lynn Martin, Laura Matricardi, Noura Mebirouk, Veronica Medici, Hanne EJ Meijers-Heijboer, Alfons Meindl, Arjen R Mensenkamp, Clare Miller, Denise Molina Gomes, Marco Montagna, Thea M Mooij, Lidia Moserle, Emmanuelle Mouret-Fourme, Anna Marie Mulligan, Katherine L Nathanson, Marie Navratilova, Heli Nevanlinna, Dieter Niederacher, Finn C Cilius Nielsen, Liene Nikitina-Zake, Kenneth Offit, Edith Olah, Olufunmilayo I Olopade, Kai-Ren Ong, Ana Osorio, Claus-Eric Ott, Domenico Palli, Sue K Park, Michael T Parsons, Inge Sokilde Pedersen, Bernard Peissel, Ana Peixoto, Pedro Pérez-Segura, Paolo Peterlongo, Annabeth Høgh Petersen, Mary E Porteous, Miguel Angel Pujana, Paolo Radice, Juliane Ramser, Johanna Rantala, Muhammad U Rashid, Kerstin Rhiem, Piera Rizzolo, Mark E Robson, Matti A Rookus, Caroline M Rossing, Kathryn J Ruddy, Catarina Santos, Claire Saule, Rosa Scarpitta, Rita K Schmutzler, Hélène Schuster, Leigha Senter, Caroline M Seynaeve, Payal D Shah, Priyanka Sharma, Vivian Y Shin, Valentina Silvestri, Jacques Simard, Christian F Singer, Anne-Bine Skytte, Katie Snape, Angela R Solano, Penny Soucy, Melissa C Southey, Amanda B Spurdle, Linda Steele, Doris Steinemann, Dominique Stoppa-Lyonnet, Agostina Stradella, Lone Sunde, Christian Sutter, Yen Y Tan, Manuel R Teixeira, Soo Hwang Teo, Mads Thomassen, Maria Grazia Tibiletti, Marc Tischkowitz, Silvia Tognazzo, Amanda E Toland, Stefania Tommasi, Diana Torres, Angela Toss, Alison H Trainer, Nadine Tung, Christi J van Asperen, Frederieke H van der Baan, Lizet E van der Kolk, Rob B van der Luijt, Liselotte P van Hest, Liliana Varesco, Raymonda Varon-Mateeva, Alessandra Viel, Jeroen Vierstraete, Roberta Villa, Anna von Wachenfeldt, Philipp Wagner, Shan Wang-Gohrke, Barbara Wappenschmidt, Jeffrey N Weitzel, Greet Wieme, Siddhartha Yadav, Drakoulis Yannoukakos, Sook-Yee Yoon, Cristina Zanzottera, Kristin K Zorn, Anthony V D'Amico, Matthew L Freedman, Mark M Pomerantz, Georgia Chenevix-Trench, Antonis C Antoniou, Susan L Neuhausen, Laura Ottini, Henriette Roed Nielsen, Timothy R Rebbeck
Oct 01, 2019
Pathogenic sequence variants (PSV) in BRCA1 or BRCA2 (BRCA1/2) are associated with increased risk and severity of prostate cancer. We evaluated whether PSVs in BRCA1/2 were associated with risk of overall prostate cancer or high...