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Results: 9286
A sinister black finding in the stomach.
Wladyslaw Januszewicz, Pippa Corrie, Hongxiang Liu, James Chan, Rebecca C Fitzgerald, Massimiliano di Pietro
Oct 08, 2019
A 68-year-old woman undergoing a routine surveillance endoscopy—part of her follow-up for a Barrett's oesophagus—was found to have a solitary, black lesion, approximately 4 mm in diameter, in the gastric body (figure).
Acrylonitrile Aged Aniline Compounds Barrett Esophagus Benzimidazoles Drug Therapy Combination endoscopy Digestive System Female Humans Liver Liver Neoplasms Magnetic Resonance Imaging Melanoma Mutation Neoplasm Metastasis Paclitaxel Prognosis Stomach Tomography X-Ray Computed Tubulin Modulators Uveal Neoplasms
Expert Elicitation of Multinomial Probabilities for Decision-Analytic Modeling
BACKGROUND: Expert elicitation is required to inform decision making when relevant "better quality" data either do not exist or cannot be collected. An example of this is to inform decisions as to whether to screen for melanoma....
Retrospective review of outcomes associated with metastatic melanoma patients treated with 1st-line BRAF-targeted therapy.
BRAF-mutant melanoma patients can theoretically access both immunotherapy and BRAF-targeted therapy as treatment for metastatic disease. BRAF-targeted therapy is increasingly used 1st line for poorer prognostic patients, so we...
Evolving treatment landscape
A 57-year-old woman diagnosed with primary melanoma was managed with a wide variety of treatments over 18 years. Given her long history of disease, the array of therapies she has received range from those no longer recommended...
Seasonal variation in diagnosis of invasive cutaneous melanoma in Eastern England and Scotland.
Fiona M Walter, Gary A Abel, Georgios Lyratzopoulos, Jane Melia, David Greenberg, David H Brewster, Helen Butler, Pippa G Corrie, Christine Campbell
Jun 26, 2015
Intravital Imaging of Adoptive T-Cell Morphology, Mobility and Trafficking Following Immune Checkpoint Inhibition in a Mouse Melanoma Model
Doreen Lau, Fabien Garçon, Anita Chandra, Laura M. Lechermann, Luigi Aloj, Edwin R. Chilvers, Pippa G. Corrie, Klaus Okkenhaug, Ferdia A. Gallagher
Aug 05, 2020
Efficient T-cell targeting, infiltration and activation within tumors is crucial for successful adoptive T-cell therapy. Intravital microscopy is a powerful tool for the visualization of T-cell behavior within tumors, as well as...
Burden of cancer trial participation
Chidiebere Nwolise, Pippa Corrie, Ray Fitzpatrick, Avinash Gupta, Crispin Jenkinson, Mark Middleton, Rubeta Matin
Jan 14, 2023
Intravital Imaging of Adoptive T-Cell Morphology, Mobility and Trafficking Following Immune Checkpoint Inhibition in a Mouse Melanoma Model.
Doreen Lau, Fabien Garçon, Anita Chandra, Laura M Lechermann, Luigi Aloj, Edwin R Chilvers, Pippa G Corrie, Klaus Okkenhaug, Ferdia A Gallagher
Jun 12, 2020
adoptive T-cell therapy Immune Checkpoint Inhibitors immunocompetent intravital imaging Melanoma Adoptive Transfer Animals Antigens Neoplasm Cell Line Tumor Cell Movement Combined Modality Therapy Disease Models Animal Fluorescent Antibody Technique Image Processing Computer-Assisted Immune Checkpoint Inhibitors Immunotherapy Adoptive Lymphocyte Activation Melanoma Experimental Mice Molecular Imaging T-Cell Antigen Receptor Specificity T-Lymphocytes
Correlating Radiomic Features of Heterogeneity on CT with Circulating Tumor DNA in Metastatic Melanoma.
Andrew B Gill, Leonardo Rundo, Jonathan CM Wan, Doreen Lau, Jeries P Zawaideh, Ramona Woitek, Fulvio Zaccagna, Lucian Beer, Davina Gale, Evis Sala, Dominique-Laurent Couturier, Pippa G Corrie, Nitzan Rosenfeld, Ferdia A Gallagher
Nov 18, 2020
Clinical imaging methods, such as computed tomography (CT), are used for routine tumor response monitoring. Imaging can also reveal intratumoral, intermetastatic, and interpatient heterogeneity, which can be quantified using...
The forgotten appearance of metastatic melanoma in the small bowel
Eva Mendes Serrao, Emily Joslin, Victoria McMorran, Caroline Hough, Cheryl Palmer, Sarah McDonald, Emma Cargill, Ashley S Shaw, Brent O’Carrigan, Christine A Parkinson, Pippa G Corrie, Timothy J Sadler
Jun 14, 2022
Abstract: Background: Melanoma is the most aggressive form of skin cancer, with a tendency to metastasise to any organ of the human body. While the most common body organs affected include liver, lungs, brain and soft tissues...
Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase
Claire M Connell, Rebecca Brais, Hayley Whitaker, Sara Upponi, Ian Beh, Jane Risdall, Pippa Corrie, Tobias Janowitz, Duncan I Jodrell
Jan 09, 2020
Cytidine Deaminase DRUG METABOLISM Gemcitabine Pancreatic Adenosquamous Carcinoma Antimetabolites Antineoplastic Carcinoma Adenosquamous Chemotherapy Adjuvant Cytidine Deaminase Deoxycytidine Female Gene Expression Humans Immunohistochemistry Magnetic Resonance Imaging Middle Aged Pancreatic Neoplasms Recurrence Retreatment Tomography X-Ray Computed Treatment Outcome Gemcitabine
The forgotten appearance of metastatic melanoma in the small bowel.
Eva Mendes Serrao, Emily Joslin, Victoria McMorran, Caroline Hough, Cheryl Palmer, Sarah McDonald, Emma Cargill, Ashley S Shaw, Brent O'Carrigan, Christine A Parkinson, Pippa G Corrie, Timothy J Sadler
Jul 15, 2022
Protocol for the OUTREACH trial: a randomised trial comparing delivery of cancer systemic therapy in three different settings
Pippa G Corrie, Margaret Moody, Victoria Wood, Linda Bavister, Toby Prevost, Richard A Parker, Ramon Sabes-Figuera, Paul McCrone, Helen Balsdon, Karen McKinnon, Brendan O'Sullivan, Ray S Tan, Stephen Ig Barclay
Nov 15, 2011
The different faces of metastatic melanoma in the gastrointestinal tract
Abstract Melanoma is the most aggressive form of skin cancer, with tendency to spread to any organ of the human body, including the gastrointestinal tract (GIT). The diagnosis of metastases to the...
Eva Mendes Serrao, Ana Maria Costa, Sergio Ferreira, Victoria McMorran, Emma Cargill, Caroline Hough, Ashley S Shaw, Brent O’Carrigan, Christine A Parkinson, Pippa G Corrie, Timothy J Sadler
Oct 05, 2022
Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase
Claire M. Connell, Rebecca Brais, Hayley Whitaker, Sara Upponi, Ian Beh, Jane Risdall, Pippa Corrie, Tobias Janowitz, Duncan I. Jodrell
Jun 06, 2020
Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase
Claire M Connell, Rebecca Brais, Hayley Whitaker, Sara Upponi, Ian Beh, Jane Risdall, Pippa Corrie, Tobias Janowitz, Duncan I Jodrell
Feb 15, 2020
BACKGROUND:Pancreatic adenosquamous carcinoma has a poor prognosis, with limited prospective trial data to guide optimal treatment. The potential impact of drug metabolism on the treatment response of patients with pancreatic...
Published by: BMC cancer
G-Quadruplexes
Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention...
The MITRE trial protocol
Nicola A Thompson, Grant Stewart, Sarah Welsh, Gary Doherty, Matthew J Robinson, B Anne Neville, Kevin Vervier, Simon R Harris, David J Adams, Katy Dalchau, David Bruce, Nikolaos Demiris, Trevor D Lawley, Pippa G Corrie
Jan 28, 2022
BACKGROUND: The gut microbiome is implicated as a marker of response to immune checkpoint inhibitors (ICI) based on preclinical mouse models and preliminary observations in limited patient series. Furthermore, early studies...
Correlating Radiomic Features of Heterogeneity on CT with Circulating Tumor DNA in Metastatic Melanoma
Andrew B Gill, Leonardo Rundo, Jonathan C. M. Wan, Doreen Lau, Jeries P. Zawaideh, Ramona Woitek, Fulvio Zaccagna, Lucian Beer, Davina Gale, Evis Sala, Dominique-Laurent Couturier, Pippa G. Corrie, Nitzan Rosenfeld, Ferdia A. Gallagher
Nov 25, 2020
Clinical imaging methods, such as computed tomography (CT), are used for routine tumor response monitoring. Imaging can also reveal intratumoral, intermetastatic, and interpatient heterogeneity, which can be quantified using...
WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma.
Nicholas Coupe, Lina Guo, Esther Bridges, Leticia Campo, Olivia Espinosa, Richard Colling, Andrea Marshall, Ashwin Nandakumar, Ruud van Stiphout, Francesca M Buffa, Pippa G Corrie, Mark R Middleton, Valentine M Macaulay
Mar 29, 2023
The different faces of metastatic melanoma in the gastrointestinal tract.
Eva Mendes Serrao, Ana Maria Costa, Sergio Ferreira, Victoria McMorran, Emma Cargill, Caroline Hough, Ashley S Shaw, Brent O'Carrigan, Christine A Parkinson, Pippa G Corrie, Timothy J Sadler
Nov 04, 2022
Melanoma is the most aggressive form of skin cancer, with tendency to spread to any organ of the human body, including the gastrointestinal tract (GIT). The diagnosis of metastases to the GIT can be difficult, as they may be...
Synthesis of Novel Regenerable 13X Zeolite-Polyimide Adsorbent Foams
A new generic synthesis method is presented for the production of a polyimide (PI)/adsorbent (80 wt% 13X zeolite) regenerable foam filter. The method uses a dual parallel reaction foaming process comprising CO 2...
Adsorbent foam Adsorption Air Filters Isotherms modelling Polyimide /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering /dk/atira/pure/subjectarea/asjc/2200/2209 name=Industrial and Manufacturing Engineering
Synthesis of Novel Regenerable 13X Zeolite-Polyimide Adsorbent Foams
A new generic synthesis method is presented for the production of a polyimide (PI)/adsorbent (80 wt% 13X zeolite) regenerable foam filter. The method uses a dual parallel reaction foaming process comprising CO 2...
Adsorbent foam Adsorption Air Filters Isotherms modelling Polyimide /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/1500/1500 name=General Chemical Engineering /dk/atira/pure/subjectarea/asjc/2200/2209 name=Industrial and Manufacturing Engineering
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