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Restoration of visual acuity with “ISOTINE” eye drops -an Ayurvedic formulation
Approximately 8 million to 2.3 million people worldwide have impaired vision due to uncorrected refractive error and cataract1. Hence the World Health Organization (WHO) has initiated Vision 2020 global program – “The right to...
Published by: IJHS Medical Association
Restoration of visual acuity with “ISOTINE” eye drops -an Ayurvedic formulation
Approximately 8 million to 2.3 million people worldwide have impaired vision due to uncorrected refractive error and cataract1. Hence the World Health Organization (WHO) has initiated Vision 2020 global program – “The right to...
Published by: IJHS Medical Association
Detectable abundance of cyanoacetylene (hc3n) predicted on reduced nitrogen-rich super-earth atmospheres
Abstract: We predict that cyanoacetylene (HC3N) is produced photochemically in the atmosphere of GJ 1132 b in abundances detectable by the James Webb Space Telescope (JWST), assuming that the atmosphere is hydrogen dominated and...
Detectable Abundance of Cyanoacetylene (HC 3 N) Predicted on Reduced Nitrogen-rich Super-Earth Atmospheres
Abstract: We predict that cyanoacetylene (HC3N) is produced photochemically in the atmosphere of GJ 1132 b in abundances detectable by the James Webb Space Telescope (JWST), assuming that the atmosphere is hydrogen dominated and...
Proteome-Wide Prediction of Acetylation Substrates
Amrita Basu
Jan 01, 0001
Eukaryotic DNA is found packaged with proteins and RNA, which forms a substance called chromatin. This packaging is dynamic and regulates access to DNA for essential cellular processes such as transcription, replication, and...
Published by: Rockefeller University
Single cell studies of mouse embryonic stem cell (mESC) differentiation by electrical impedance measurements in a microfluidic device.
Vedantic variations in the presence of Europe
Ankur Barua
May 05, 2017
Abstract
We will offer in this essay an analytic overview of four texts from the second half of the nineteenth century which elaborated different variations on the Hindu dharma. These are Rajnarayan Basu’s Hindu...
Enhancer-Promoter Communication
Cis-regulatory elements such as enhancers can be located even a million base pairs away from their cognate promoter and yet modulate gene transcription. Indeed, the 3D organisation of chromatin enables the establishment of...
Triangulations of monotone families I
Let K⊂Rn be a compact definable set in an o-minimal structure over R, for example, a semi-algebraic or a subanalytic set. A definable family {Sδ|0<δ∈R} of compact subsets of K is called a monotone family if Sδ⊂Sη for all...
Early Phase Clinical Trial Designs - State of Play and Adapting for the Future.
The process of anti-cancer drug development is complex, with high attrition rates. Factors that may optimise this process include well-constructed and relevant pre-clinical testing and use of biomarkers for patient selection....
RNA, Genome Output and Input.
RNA, the transcriptional output of genomes, not only templates protein synthesis or directly engages in catalytic functions, but can feed back to the genome and serve as regulatory input for gene expression. Transcripts...
Inner-View of Nanomaterial Incited Protein Conformational Changes
Nanoparticle bioreactivity critically depends upon interaction between proteins and nanomaterials (NM). The formation of the "protein corona" (PC) is the effect of such nanoprotein interactions. PC has a wide usage in...
Update on the Genetics of and Systemic Therapy Options for Combined Hepatocellular Cholangiocarcinoma.
Alexander A Azizi, Andreas V Hadjinicolaou, Carla Goncalves, Adam Duckworth, Bristi Basu
Sep 28, 2020
Combined hepatocellular-cholangiocarcinoma (cHCC-ICC) is an uncommon and aggressive form of primary liver cancer. Currently, there are no international guidelines for optimal management. For localized tumors, radical resection...
RNA, Genome Output and Input
RNA, the transcriptional output of genomes, not only templates protein synthesis or directly engages in catalytic functions, but can feed back to the genome and serve as regulatory input for gene expression. Transcripts...
Dynamic monitoring of single cell lysis in an impedance-based microfluidic device.
Impedance spectroscopy Microfluidics Real-time measurements Single cell trapping Stem Cells Animals Cell Membrane Dimethylpolysiloxanes Electric Capacitance Electric Impedance Embryonic Stem Cells Equipment Design Evaluation Studies as Topic Lab-On-A-Chip Devices Mice Microfluidic Analytical Techniques Models Theoretical Single-Cell Analysis
Calculation of 3D genome structures for comparison of chromosome conformation capture experiments with microscopy
Single-cell chromosome conformation capture approaches are revealing the extent of cell-to-cell variability in the organization and packaging of genomes. These single-cell methods, unlike their multi-cell counterparts, allow...
A zebrafish model for ocular tuberculosis.
Ocular tuberculosis (TB) commonly causes severe inflammation and vision loss in TB-endemic countries. The mechanism by which tuberculous infection becomes established in the eye is poorly understood. We have developed the...
Changing the narratives for patient safety
Mary Dixon-Woods is supported by a Wellcome Trust Senior Investigator award (WT097899).
Triangulations of monotone families I
Let K⊂Rn be a compact definable set in an o-minimal structure over R, for example, a semi-algebraic or a subanalytic set. A definable family {Sδ|0<δ∈R} of compact subsets of K is called a monotone family if Sδ⊂Sη for all...
A microfluidic platform for trapping, releasing and super-resolution imaging of single cells.
Ying Zhou, Srinjan Basu, Kai J Wohlfahrt, Steven F Lee, David Klenerman, Ernest D Laue, Ashwin A Seshia
Apr 08, 2016
Diagnosis of coeliac disease by flow cytometry of intraepithelial lymphocytes
Kaninika Basu, Hannah Creasey, Nina Bruggemann, Jennifer Stevens, David Bloxham, Jeremy Mark Woodward
Apr 22, 2021
OBJECTIVE: The analysis of intraepithelial lymphocytes (IELs) by flow cytometry of duodenal biopsies-the 'IEL' lymphogram-has been proposed as a diagnostic test for coeliac disease. However, its clinical applicability has been...
Update on the Genetics of and Systemic Therapy Options for Combined Hepatocellular Cholangiocarcinoma
Alexander A. Azizi, Andreas V. Hadjinicolaou, Carla Goncalves, Adam Duckworth, Bristi Basu
Oct 09, 2020
Combined hepatocellular-cholangiocarcinoma (cHCC-ICC) is an uncommon and aggressive form of primary liver cancer. Currently, there are no international guidelines for optimal management. For localized tumors, radical resection...
Three-Dimensional Super-Resolution in Eukaryotic Cells Using the Double-Helix Point Spread Function
AR Carr, A Ponjavic, S Basu, J McColl, AM Santos, S Davis, ED Laue, D Klenerman, SF Lee
May 10, 2017
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