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Interview with Deitre Owens Helvy
This interview was conducted by Winthrop student Michaela Bessinger with Deitre Owens Helvy as part of Project 2020: A Collaborative Oral History. Helvy details her experiences as a Black female educator in Greenville County...
Covid-19 pandemic 2020 Education Virtual learning Greenville County School District social justice race
Published by: Winthrop University
Interview with Mazie Owens - OH 204
Mazie Owens
Jan 01, 0001
In her interview with Michael Cooke, Mazie Owens discusses her experience and efforts to encourage the black community to register to vote in South Carolina. Mrs. Owens details her involvement in the efforts to assist people...
Published by: Winthrop University
Advances in modelling the human microbiome-gut-brain axis in vitro.
The human gut microbiome has emerged as a key player in the bidirectional communication of the gut-brain axis, affecting various aspects of homeostasis and pathophysiology. Until recently, the majority of studies that seek to...
In Vitro Models for Studying Respiratory Host-Pathogen Interactions.
Respiratory diseases and lower respiratory tract infections are among the leading cause of death worldwide and, especially given the recent severe acute respiratory syndrome coronavirus-2 pandemic, are of high and prevalent...
In Vitro Models for Studying Respiratory Host–Pathogen Interactions
Abstract: Respiratory diseases and lower respiratory tract infections are among the leading cause of death worldwide and, especially given the recent severe acute respiratory syndrome coronavirus‐2 pandemic, are of high and...
Review Reviews host–pathogens immunology In vitro models Infection lungs pathogens Respiratory System
Published by: Advanced Biology
Combined optical and electronic sensing of epithelial cells using planar organic transistors.
A planar, conducting-polymer-based transistor for combined optical and electronic monitoring of live cells provides a unique platform for monitoring the health of cells in vitro. Monitoring of MDCK-I epithelial cells over...
A human-derived neurovascular unit in vitro model to study the effects of cellular cross-talk and soluble factors on barrier integrity.
Chiara Barberio, Aimee Withers, Yash Mishra, Pierre-Olivier Couraud, Ignacio A Romero, Babette Weksler, Róisín M Owens
Dec 19, 2022
Advances in Engineering Human Tissue Models.
Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate the investigation and understanding of specific biological events and processes under different conditions. The quality of such...
Advances in Engineering Human Tissue Models
Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate the investigation and understanding of specific biological events and processes under different conditions. The quality of such...
Sensing of EGTA Mediated Barrier Tissue Disruption with an Organic Transistor.
Barrier tissue protects the body against external factors by restricting the passage of molecules. The gastrointestinal epithelium is an example of barrier tissue with the primary purpose of allowing the passage of ions and...
New Classroom Building Named Owens Hall
Winthrop University
Jan 01, 0001
Owens Hall has been named in honor of Winthrop volunteer and supporter Glenda Pittman Howens. All academic units will use the facility.
Published by: Winthrop University
Organic electronic transmembrane device for hosting and monitoring 3D cell cultures.
Charalampos Pitsalidis, Douglas van Niekerk, Chrysanthi-Maria Moysidou, Alexander J Boys, Aimee Withers, Romane Vallet, Róisín M Owens
Oct 18, 2022
3D cell models have made strides in the past decades in response to failures of 2D cultures to translate targets during the drug discovery process. Here, we report on a novel multiwell plate bioelectronic platform, namely, the...
All-plastic electrochemical transistor for glucose sensing using a ferrocene mediator.
Na Young Shim, Daniel A Bernards, Daniel J Macaya, John A Defranco, Maria Nikolou, Róisín M Owens, George G Malliaras
Mar 27, 2018
We demonstrate a glucose sensor based on an organic electrochemical transistor (OECT) in which the channel, source, drain, and gate electrodes are made from the conducting polymer poly(3,4-ethylenedioxythiophene) doped with...
Rock Hill Fire Department Provides Update on Owens Hall Fire
Winthrop University
Jan 01, 0001
The fire started outside the building on a small section of flat roof located where Owens Hall and Bancroft Annex join. Fire investigators reviewed and ruled out the mechanical room, HVAC and elevator systems.
Published by: Winthrop University
A highly sensitive molecular structural probe applied to in situ biosensing of metabolites using PEDOT
Ellasia Tan, Anna-Maria Pappa, Charalampos Pitsalidis, James Nightingale, Sebastian Wood, Fernando A Castro, Róisín M Owens, Ji-Seon Kim
Oct 14, 2019
3D Bioelectronics with a Remodellable Matrix for Long-Term Tissue Integration and Recording.
Alexander J Boys, Alejandro Carnicer-Lombarte, Amparo Güemes-Gonzalez, Douglas C van Niekerk, Sam Hilton, Damiano G Barone, Christopher M Proctor, Róisín M Owens, George G Malliaras
Dec 21, 2022
Bioelectronics hold the key for understanding and treating disease. However, achieving stable, long-term interfaces between electronics and the body remains a challenge. Implantation of a bioelectronic device typically initiates...
Conducting Polymer Scaffolds Based on Poly(3,4-ethylenedioxythiophene) and Xanthan Gum for Live-Cell Monitoring.
Isabel Del Agua, Sara Marina, Charalampos Pitsalidis, Daniele Mantione, Magali Ferro, Donata Iandolo, Ana Sanchez-Sanchez, George G Malliaras, Róisín M Owens, David Mecerreyes
Sep 08, 2018
Conducting polymer scaffolds can promote cell growth by electrical stimulation, which is advantageous for some specific type of cells such as neurons, muscle, or cardiac cells. As an additional feature, the measure of their...
Direct metabolite detection with an n-type accumulation mode organic electrochemical transistor.
Anna Maria Pappa, David Ohayon, Alexander Giovannitti, Iuliana Petruta Maria, Achilleas Savva, Ilke Uguz, Jonathan Rivnay, Iain McCulloch, Róisín M Owens, Sahika Inal
Nov 01, 2018
The inherent specificity and electrochemical reversibility of enzymes poise them as the biorecognition element of choice for a wide range of metabolites. To use enzymes efficiently in biosensors, the redox centers of the protein...
Self-Assembly of Mammalian-Cell Membranes on Bioelectronic Devices with Functional Transmembrane Proteins.
Han-Yuan Liu, Anna-Maria Pappa, Aimie Pavia, Charalampos Pitsalidis, Quentin Thiburce, Alberto Salleo, Róisín M Owens, Susan Daniel
Jun 02, 2020
Transmembrane proteins (TMPs) regulate processes occurring at the cell surface and are essential gatekeepers of information flow across the membrane. TMPs are difficult to study, given the complex environment of the membrane and...
Biosensor for Multimodal Characterization of an Essential ABC Transporter for Next-Generation Antibiotic Research.
Karan Bali, Charlotte Guffick, Reece McCoy, Zixuan Lu, Clemens F Kaminski, Ioanna Mela, Róisín M Owens, Hendrik W van Veen
Apr 02, 2023
MsbA PEDOT:PSS Atomic force microscopy Biosensor electrochemical impedance spectroscopy Electrophysiology structured illumination microscopy Supported lipid bilayer ATP-Binding Cassette Transporters Bacterial Proteins Lipid Bilayers Anti-Bacterial Agents Escherichia coli Adenosine Triphosphate Biosensing Techniques
Biomimetic Electronic Devices for Measuring Bacterial Membrane Disruption.
Charalampos Pitsalidis, Anna-Maria Pappa, Mintu Porel, Christine M Artim, Gregorio C Faria, Duc D Duong, Christopher A Alabi, Susan Daniel, Alberto Salleo, Róisín M Owens
Sep 17, 2018
Dual Mode Sensing of Binding and Blocking of Cancer Exosomes to Biomimetic Human Primary Stem Cell Surfaces.
Johana Uribe, Walther C Traberg, Adel Hama, Victor Druet, Zeinab Mohamed, Amanda Ooi, Anna-Maria Pappa, Miriam Huerta, Sahika Inal, Róisín M Owens, Susan Daniel
Nov 24, 2021
Optical and Electronic Ion Channel Monitoring from Native Human Membranes.
Anna-Maria Pappa, Han-Yuan Liu, Walther Traberg-Christensen, Quentin Thiburce, Achilleas Savva, Aimie Pavia, Alberto Salleo, Susan Daniel, Róisín M Owens
Jun 02, 2020
Transmembrane proteins represent a major target for modulating cell activity, both in terms of therapeutics drugs and for pathogen interactions. Work on screening such therapeutics or identifying toxins has been severely limited...
3D Cell Culture
Sahika Inal, Adel Hama, Magali Ferro, Charalampos Pitsalidis, Julie Oziat, Donata Iandolo, Anna-Maria Pappa, Mikhael Hadida, Miriam Huerta, David Marchat, Pascal Mailley, Róisín M Owens
Nov 15, 2019
This work reports the design of a live-cell monitoring platform based on a
macroporous scaffold of a conducting polymer, poly(3,4-ethylene dioxythiophene):
poly(styrenesulfonate). The conducting polymer scaffolds support 3D
cell...
Biomimetic and electroactive 3D scaffolds for human neural crest-derived stem cell expansion and osteogenic differentiation
Donata Iandolo, Jonathan Sheard, Galit Karavitas Levy, Charalampos Pitsalidis, Ellasia Tan, Anthony Dennis, Ji-Seon Kim, Athina E. Markaki, Darius Widera, Róisín M. Owens
Dec 03, 2020
Abstract: Osteoporosis is a skeletal disease characterized by bone loss and bone microarchitectural deterioration. The combination of smart materials and stem cells represents a new therapeutic approach. In the present study...
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