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Results: 12780
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.
Parasvi S Patel, Karan Joshua Abraham, Kiran Kumar Naidu Guturi, Marie-Jo Halaby, Zahra Khan, Luis Palomero, Brandon Ho, Shili Duan, Jonathan St-Germain, Arash Algouneh, Francesca Mateo, Samah El Ghamrasni, Haithem Barbour, Daniel R Barnes, Jonathan Beesley, Otto Sanchez, Hal K Berman, Grant W Brown, El Bachir Affar, Georgia Chenevix-Trench, Antonis C Antoniou, Cheryl H Arrowsmith, Brian Raught, Miquel Angel Pujana, Karim Mekhail, Anne Hakem, Razqallah Hakem
Feb 15, 2021
Germline mutations in BRCA1 and BRCA2 (BRCA1/2) genes considerably increase breast and ovarian cancer risk. Given that tumors with these mutations have elevated genomic instability, they exhibit relative vulnerability to certain...
R/BHC
BACKGROUND: Although the use of clustering methods has rapidly become one of the standard computational approaches in the literature of microarray gene expression data analysis, little attention has been paid to uncertainty in...
Beyond dehydrocoupling
David J. Liptrot, Merle Arrowsmith, Annie L. Colebatch, Terrance J. Hadlington, Michael S. Hill, Gabriele Kociok-Kohn, Mary F. Mahon
Dec 07, 2015
The alkaline earth bis(trimethylsilyl)amides, [Ae{N(SiMe3)2}2(THF)2] [Ae = Mg, Ca, Sr], are effective pre-catalysts for boron-nitrogen bond formation through the desilacoupling of amines, RR’NH (R = alkyl, aryl; R′ = H, alkyl...
The Expansion of Approximant /r/ in Dutch
Renée Van Bezooijen
Sep 30, 2014
In present-day Standard Dutch as spoken in the Netherlands, three main categories of pronunciation variants of Irl can be distinguished, namely alveolar /r/, uvular /r/, and approximant /r/. Approximant /r/, the focus of this...
Published by: Atlantic Provinces Linguistic Association
Alphonse R. Dochez, 1925
The Rockefeller University
Jan 01, 0001
Alphonse R. Dochez. Etiology of Scarlet Fever
Lecture delivered January 17th, 1925
Posted with permission
Published by: J.B. Lippincott Company
Florence R. Sabin, 1915
The Rockefeller University
Jan 01, 0001
Prof. Florence R. Sabin. The Method of Growth of the Lymphatic System
Lecture delivered December 18th, 1915
Published by: J.B. Lippincott Company
Personality Antecedents of EWoM in Determining Online Customer Purchase Behavior
Electronic word of mouth (EWoM) is similar to the standard word of mouth- the only difference is, the use of Internet as a base in EWoM. By understanding the personality antecedents of EWoM, the consumer buyer beahviour could be...
Published by: IGI Global Scientific Publishing
Beyond dehydrocoupling
David J. Liptrot, Merle Arrowsmith, Annie L. Colebatch, Terrance J. Hadlington, Michael S. Hill, Gabriele Kociok-Kohn, Mary F. Mahon
Dec 07, 2015
The alkaline earth bis(trimethylsilyl)amides, [Ae{N(SiMe3)2}2(THF)2] [Ae = Mg, Ca, Sr], are effective pre-catalysts for boron-nitrogen bond formation through the desilacoupling of amines, RR’NH (R = alkyl, aryl; R′ = H, alkyl...
The Expansion of Approximant /r/ in Dutch
Renée Van Bezooijen
Sep 30, 2014
In present-day Standard Dutch as spoken in the Netherlands, three main categories of pronunciation variants of Irl can be distinguished, namely alveolar /r/, uvular /r/, and approximant /r/. Approximant /r/, the focus of this...
Published by: Atlantic Provinces Linguistic Association
Bayesian Spatial Modelling with R-INLA
The principles behind the interface to continuous domain spatial models in the R- INLA software package for R are described. The integrated nested Laplace approximation (INLA) approach proposed by Rue, Martino, and Chopin (2009)...
Bayesian Spatial Modelling with R-INLA
The principles behind the interface to continuous domain spatial models in the R- INLA software package for R are described. The integrated nested Laplace approximation (INLA) approach proposed by Rue, Martino, and Chopin (2009)...
Using R and Bioconductor for proteomics data analysis.
This review presents how R, the popular statistical environment and programming language, can be used in the frame of proteomics data analysis. A short introduction to R is given, with special emphasis on some of the features...
A farewell to <i>R</i>
The time-dependent reproduction number, Rt, is a key metric used by epidemiologists to assess the current state of an outbreak of an infectious disease. This quantity is usually estimated using...
Orchestrating privacy-protected big data analyses of data from different resources with R and DataSHIELD.
Yannick Marcon, Tom Bishop, Demetris Avraam, Xavier Escriba-Montagut, Patricia Ryser-Welch, Stuart Wheater, Paul Burton, Juan R González
Apr 09, 2021
Combined analysis of multiple, large datasets is a common objective in the health- and biosciences. Existing methods tend to require researchers to physically bring data together in one place or follow an analysis plan and share...
Explanatory Adequacy in Phonology
Eric Russell Webb
Aug 01, 2013
This work reexamines phonological variation particular to the /R/ of convergent French, departing from the hypothesis that a deductive approach to this question can offer explanatory advantages. In contrast to data-driven...
Published by: Atlantic Provinces Linguistic Association
Re and<sup> 99m</sup>Tc complexes of BodP<sub>3</sub> – multi-modality imaging probes
Laura H. Davies, Benjamin B. Kasten, Paul D. Benny, R Arrowsmith, Haobo Ge, Sofia Pascu, Stan W. Botchway, William Clegg, Ross W. Harrington, Lee J. Higham
Dec 21, 2014
A fluorescent tridentate phosphine, BodP3 (2), forms rhenium complexes which effectively image cancer cells. Related technetium analogues are also readily prepared and have potential as dual SPECT/fluorescent biological probes.
Asymmetric Information and R&D Disclosure
We examine how asymmetric information in financial markets affects voluntary research and development (R&D) disclosure, considering scientific publications as a disclosure channel. Difference-in-differences regressions...
Asymmetric Information and R&D Disclosure
We examine how asymmetric information in financial markets affects voluntary research and development (R&D) disclosure, considering scientific publications as a disclosure channel. Difference-in-differences regressions...
The CBI-R detects early behavioural impairment in genetic frontotemporal dementia.
Annabel Nelson, Lucy L Russell, Georgia Peakman, Rhian S Convery, Arabella Bouzigues, Caroline V Greaves, Martina Bocchetta, David M Cash, John C van Swieten, Lize Jiskoot, Fermin Moreno, Raquel Sanchez-Valle, Robert Laforce, Caroline Graff, Mario Masellis, Maria Carmela Tartaglia, James B Rowe, Barbara Borroni, Elizabeth Finger, Matthis Synofzik, Daniela Galimberti, Rik Vandenberghe, Alexandre de Mendonça, Chris R Butler, Alexander Gerhard, Simon Ducharme, Isabelle Le Ber, Isabel Santana, Florence Pasquier, Johannes Levin, Markus Otto, Sandro Sorbi, Jonathan D Rohrer, Genetic FTD Initiative (GENFI)
Sep 10, 2022
INTRODUCTION: Behavioural dysfunction is a key feature of genetic frontotemporal dementia (FTD) but validated clinical scales measuring behaviour are lacking at present. METHODS: We assessed behaviour using the revised version...
Optimal protamine dosing after cardiopulmonary bypass
Lachlan F Miles, Christiana Burt, Joseph Arrowsmith, Mikel A Mckie, Sofia S Villar, Pooveshnie Govender, Ruth Shaylor, Zihui Tan, Ravi de Silva, Florian Falter
Jun 17, 2021
BACKGROUND: The dose of protamine required following cardiopulmonary bypass (CPB) is often determined by the dose of heparin required pre-CPB, expressed as a fixed ratio. Dosing based on mathematical models of heparin clearance...
Optimal protamine dosing after cardiopulmonary bypass
Lachlan F Miles, Christiana Burt, Joseph Arrowsmith, Mikel A Mckie, Sofia S Villar, Pooveshnie Govender, Ruth Shaylor, Zihui Tan, Ravi de Silva, Florian Falter
Jul 28, 2021
Background
The dose of protamine required following cardiopulmonary bypass (CPB) is often determined by the dose of heparin required pre-CPB, expressed as a fixed ratio. Dosing based on mathematical models of heparin...
Published by: PLoS Medicine
rpsftm
Treatment switching in a randomised controlled trial occurs when participants change from their randomised treatment to the other trial treatment during the study. Failure to account for treatment switching in the analysis (i.e....
Timing the r-process Enrichment of the Ultra-faint Dwarf Galaxy Reticulum II
Abstract
The ultra-faint dwarf galaxy Reticulum II (Ret II) exhibits a unique chemical evolution history, with
Joshua D Simon, Thomas M Brown, Burcin Mutlu-Pakdil, Alexander P Ji, Alex Drlica-Wagner, Roberto J Avila, Clara E Martinez-Vazquez, Ting S Li, Eduardo Balbinot, Keith Bechtol, Anna Frebel, Marla Geha, Terese T Hansen, David J James, Andrew B Pace, M Aguena, O Alves, F Andrade-Oliveira, J Annis, D Bacon, E Bertin, D Brooks, DL Burke, A Carnero Rosell, M Carrasco Kind, J Carretero, M Costanzi, LN Da Costa, J De Vicente, S Desai, P Doel, S Everett, I Ferrero, J Frieman, J Garcia-Bellido, M Gatti, DW Gerdes, D Gruen, RA Gruendl, J Gschwend, G Gutierrez, SR Hinton, DL Hollowood, K Honscheid, K Kuehn, N Kuropatkin, JL Marshall, J Mena-Fernandez, R Miquel, A Palmese, F Paz-Chinchon, MES Pereira, A Pieres, AA Plazas Malagon, M Raveri, M Rodriguez-Monroy, E Sanchez, B Santiago, V Scarpine, I Sevilla-Noarbe, M Smith, E Suchyta, MEC Swanson, G Tarle, C To, M Vincenzi, N Weaverdyck, RD Wilkinson
Feb 10, 2023
A quantitative analysis 0f word-final /r/-deletion in Brazilian Portugese
Walcir Cardoso
Jul 18, 2013
This study provides a quantitative analysis for the process of word-final /r/-deletion in the dialect of Portuguese spoken in the city of Belem, in northern Brazil. Two linguistic and four extralinguistic factors are considered...
Published by: Atlantic Provinces Linguistic Association
Selection of Important Features for Optimizing Crop Yield Prediction
In agriculture, crop yield prediction is critical. Crop yield depends on various features including geographic, climate and biological. This research article discusses five Feature Selection (FS) algorithms namely Sequential...
Published by: IGI Global Scientific Publishing
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