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A Practical Guide to Modeling and Conducting a Cost-Effectiveness Analysis of Companion Biomarker Tests for Targeted Therapies Using R
Despite the increasing number of potential biomarkers identified in laboratories and reported in much literature, the adoption of biomarkers routinely available in clinical practice to inform treatment decisions is very limited....
R/BHC
BACKGROUND: Although the use of clustering methods has rapidly become one of the standard computational approaches in the literature of microarray gene expression data analysis, little attention has been paid to uncertainty in...
The Expansion of Approximant /r/ in Dutch
Renée Van Bezooijen
Sep 30, 2014
In present-day Standard Dutch as spoken in the Netherlands, three main categories of pronunciation variants of Irl can be distinguished, namely alveolar /r/, uvular /r/, and approximant /r/. Approximant /r/, the focus of this...
Published by: Atlantic Provinces Linguistic Association
Alphonse R. Dochez, 1925
The Rockefeller University
Jan 01, 0001
Alphonse R. Dochez. Etiology of Scarlet Fever
Lecture delivered January 17th, 1925
Posted with permission
Published by: J.B. Lippincott Company
Florence R. Sabin, 1915
The Rockefeller University
Jan 01, 0001
Prof. Florence R. Sabin. The Method of Growth of the Lymphatic System
Lecture delivered December 18th, 1915
Published by: J.B. Lippincott Company
Personality Antecedents of EWoM in Determining Online Customer Purchase Behavior
Electronic word of mouth (EWoM) is similar to the standard word of mouth- the only difference is, the use of Internet as a base in EWoM. By understanding the personality antecedents of EWoM, the consumer buyer beahviour could be...
Published by: IGI Global Scientific Publishing
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.
Parasvi S Patel, Karan Joshua Abraham, Kiran Kumar Naidu Guturi, Marie-Jo Halaby, Zahra Khan, Luis Palomero, Brandon Ho, Shili Duan, Jonathan St-Germain, Arash Algouneh, Francesca Mateo, Samah El Ghamrasni, Haithem Barbour, Daniel R Barnes, Jonathan Beesley, Otto Sanchez, Hal K Berman, Grant W Brown, El Bachir Affar, Georgia Chenevix-Trench, Antonis C Antoniou, Cheryl H Arrowsmith, Brian Raught, Miquel Angel Pujana, Karim Mekhail, Anne Hakem, Razqallah Hakem
Feb 15, 2021
Germline mutations in BRCA1 and BRCA2 (BRCA1/2) genes considerably increase breast and ovarian cancer risk. Given that tumors with these mutations have elevated genomic instability, they exhibit relative vulnerability to certain...
The Expansion of Approximant /r/ in Dutch
Renée Van Bezooijen
Sep 30, 2014
In present-day Standard Dutch as spoken in the Netherlands, three main categories of pronunciation variants of Irl can be distinguished, namely alveolar /r/, uvular /r/, and approximant /r/. Approximant /r/, the focus of this...
Published by: Atlantic Provinces Linguistic Association
Bayesian Spatial Modelling with R-INLA
The principles behind the interface to continuous domain spatial models in the R- INLA software package for R are described. The integrated nested Laplace approximation (INLA) approach proposed by Rue, Martino, and Chopin (2009)...
Bayesian Spatial Modelling with R-INLA
The principles behind the interface to continuous domain spatial models in the R- INLA software package for R are described. The integrated nested Laplace approximation (INLA) approach proposed by Rue, Martino, and Chopin (2009)...
Random Strong Discrete Morse Theory
Nikolai X Peralta
Jan 01, 0001
In topology, simplicial complexes can be reduced to smaller complexes of the same simple homotopy type through a series of elementary collapses. It is a common goal to try to find the smallest complex that is of the same simple...
Discrete Morse Theory random strong topology Barmak Minian strong collapses simplicial complex mathematics Physical Sciences and Mathematics
Published by: Ursinus College
Groups satisfying a strong complement property
Let G=NH be a finite group where N is normal in G and H is a complement of N in G. For a given generating sequence (h1,…,hd) of H we say that (N,(h1,…,hd)) satisfies the strong complement property, if 〈h1 x1,…,hd xd〉 is a...
Transport of strong-coupling polarons in optical lattices
We study the transport of ultracold impurity atoms immersed in a Bose-Einstein condensate (BEC) and trapped in a tight optical lattice. Within the strong-coupling regime, we derive an extended Hubbard model describing the...
Using R and Bioconductor for proteomics data analysis.
This review presents how R, the popular statistical environment and programming language, can be used in the frame of proteomics data analysis. A short introduction to R is given, with special emphasis on some of the features...
Transport of strong-coupling polarons in optical lattices
We study the transport of ultracold impurity atoms immersed in a Bose-Einstein condensate (BEC) and trapped in a tight optical lattice. Within the strong-coupling regime, we derive an extended Hubbard model describing the...
A farewell to <i>R</i>
The time-dependent reproduction number, Rt, is a key metric used by epidemiologists to assess the current state of an outbreak of an infectious disease. This quantity is usually estimated using...
Rigorous Bounds on Strong Interaction Coupling Constants
James Bruce Healy
Jan 01, 0001
We investigate the problem of deriving bounds on strong interaction scattering amplitudes from the results of axiomatic field theory.
Published by: Rockefeller University
Orchestrating privacy-protected big data analyses of data from different resources with R and DataSHIELD.
Yannick Marcon, Tom Bishop, Demetris Avraam, Xavier Escriba-Montagut, Patricia Ryser-Welch, Stuart Wheater, Paul Burton, Juan R González
Apr 09, 2021
Combined analysis of multiple, large datasets is a common objective in the health- and biosciences. Existing methods tend to require researchers to physically bring data together in one place or follow an analysis plan and share...
Metabolic Consequences of Long-Term Rapamycin Exposure on Common Marmoset Monkeys (Callithrix Jacchus)
Corinna N. Ross, A. Salmon, R. Strong, E. Fernandez, M. Javors, A. Richardson, S. Tardif
Jan 01, 2015
Rapamycin has been shown to extend lifespan in rodent models, but the effects on metabolic health and function have been widely debated in both clinical and translational trials. Prior to rapamycin being used as a treatment to...
Published by: Digital Commons @ Texas A&M University-San Antonio
Groups satisfying a strong complement property
Let G=NH be a finite group where N is normal in G and H is a complement of N in G. For a given generating sequence (h1,…,hd) of H we say that (N,(h1,…,hd)) satisfies the strong complement property, if 〈h1 x1,…,hd xd〉 is a...
Explanatory Adequacy in Phonology
Eric Russell Webb
Aug 01, 2013
This work reexamines phonological variation particular to the /R/ of convergent French, departing from the hypothesis that a deductive approach to this question can offer explanatory advantages. In contrast to data-driven...
Published by: Atlantic Provinces Linguistic Association
Asymmetric Information and R&D Disclosure
We examine how asymmetric information in financial markets affects voluntary research and development (R&D) disclosure, considering scientific publications as a disclosure channel. Difference-in-differences regressions...
Asymmetric Information and R&D Disclosure
We examine how asymmetric information in financial markets affects voluntary research and development (R&D) disclosure, considering scientific publications as a disclosure channel. Difference-in-differences regressions...
Metabolic Consequences of Long-Term Rapamycin Exposure on Common Marmoset Monkeys (Callithrix Jacchus)
Corinna N. Ross, A. Salmon, R. Strong, E. Fernandez, M. Javors, A. Richardson, S. Tardif
Jan 01, 2015
Rapamycin has been shown to extend lifespan in rodent models, but the effects on metabolic health and function have been widely debated in both clinical and translational trials. Prior to rapamycin being used as a treatment to...
Published by: Digital Commons @ Texas A&M University-San Antonio
Malevolent Node Detection Based on Network Parameters Mining in Wireless Sensor Networks
The exponential growth of the internet of things and united applications have renewed the scholarly world to grow progressively proficient routing strategies. Quality of service (QoS) and reduced power consumption are the major...
Published by: IGI Global Scientific Publishing
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