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Is calorie labelling on menus the solution to obesity?
Giles SH Yeo
Jul 10, 2022
From April 2022, as part of the UK government’s new obesity strategy, it is now compulsory for all larger restaurant and cafes in the UK to include calorie labelling on their menus. Is this legislation, however, likely to be...
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The Role of Kiss1 Neurons As Integrators of Endocrine, Metabolic, and Environmental Factors in the Hypothalamic-Pituitary-Gonadal Axis.
Kisspeptin-GPR54 signaling in the hypothalamus is required for reproduction and fertility in mammals. Kiss1 neurons are key regulators of gonadotropin-releasing hormone (GnRH) release and modulation of the...
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The genetics of obesity
Ruth JF Loos, Giles SH Yeo
Oct 25, 2021
The prevalence of obesity has tripled over the past four decades, imposing an enormous burden on people's health. Polygenic (or common) obesity and rare, severe, early-onset monogenic obesity are often polarized as distinct...
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Exploratory Study of Societal Contexts and Industry Performance
There is inconclusive evidence on the effectiveness of information and communication technologies (ICT) at the industry level. Using the influence-impact model as a theoretical framework, the authors apply data mining techniques...
Are ICTs Really That Important in Driving Industry Performance?
A decision tree is used to investigate how information and communication technologies (ICTs) and financial factors influence the performance of service and manufacturing industries globally. Industry performance is measured by...
DEFLATE compression algorithm corrects for overestimation of phylogenetic diversity by Grantham approach to single-nucleotide polymorphism classification.
Improvements in speed and cost of genome sequencing are resulting in increasing numbers of novel non-synonymous single nucleotide polymorphisms (nsSNPs) in genes known to be associated with disease. The large number of nsSNPs...
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Nonparametric, tuning-free estimation of S-shaped functions
We consider the nonparametric estimation of an S-shaped regression function. The least squares estimator provides a very natural, tuning-free approach, but results in a non-convex optimisation problem, since the inflection point...
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A web-database of mammalian morphology and a reanalysis of placental phylogeny
RJ Asher
Jun 13, 2011
Background: Recent publications concerning the interordinal phylogeny of placental mammals have converged on a common signal, consisting of four major radiations with some ambiguity regarding the placental root. The DNA data...
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