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Local Food System and Challenges and Successes of Modern
This panel will explore the explosion in craft brewing in the Carolinas from a gendered perspective, specifically from the perspective of local women brewers, highlighting Rachael Hudson, owner of Pilot Brewing, Carol Waggoner...
Published by: Winthrop University
Predicting clinical diagnosis in Huntington's disease
Sarah L Mason, Richard E Daws, Eyal Soreq, Eileanoir B Johnson, Rachael I Scahill, Sarah J Tabrizi, Roger A Barker, Adam Hampshire
Apr 19, 2018
Fronto-striatal circuits for cognitive flexibility in far from onset Huntington's disease
Christelle Langley, Sarah Gregory, Katie Osborne-Crowley, Claire O'Callaghan, Paul Zeun, Jessica Lowe, Eileanoir B Johnson, Marina Papoutsi, Rachael I Scahill, Geraint Rees, Sarah J Tabrizi, Trevor W Robbins, Barbara Jacquelyn Sahakian
Nov 03, 2020
OBJECTIVES: Cognitive flexibility, which is key for adaptive decision-making, engages prefrontal cortex (PFC)-striatal circuitry and is impaired in both manifest and premanifest Huntington's disease (pre-HD). The aim of this...
mRNA processing in mutant zebrafish lines generated by chemical and CRISPR-mediated mutagenesis produces unexpected transcripts that escape nonsense-mediated decay.
Jennifer L Anderson, Timothy S Mulligan, Meng-Chieh Shen, Hui Wang, Catherine M Scahill, Frederick J Tan, Shao J Du, Elisabeth M Busch-Nentwich, Steven A Farber
Jan 24, 2018
As model organism-based research shifts from forward to reverse genetics approaches, largely due to the ease of genome editing technology, a low frequency of abnormal phenotypes is being observed in lines with mutations...
Nutrient limitation in freshwater streams in the South Carolina Piedmont
Rachael Rowe
Jan 01, 0001
Availability of nutrients, particularly nitrogen (N) and phosphorus (P), is a key driver of microbial growth and metabolism in freshwater ecosystems. Microbial biofilms composed of both autotrophs and heterotrophs play crucial...
Published by: Winthrop University
We Are Displaced, But We Are More Than That
Rachael Kiddey
Mar 16, 2023
This article charts the development of The Made in Migration Collective, a coalition of displaced people, academics, and creative professionals that was developed during a recently completed British Academy postdoctoral...
The Dual Role of OCA-B in B Cell Development and Signaling
Rachael Siegel
Jan 01, 0001
OCA-B (Oct coactivator from B cells) is a B-cell specific coactivator of transcription that acts in conjunction with the ubiquitously expressed activator, OCT-1 or the B cell-restricted OCT-2. OCT-1 or OCT-2 can bind an upstream...
Published by: Rockefeller University
Leakage does not fully offset soy supply-chain efforts to reduce deforestation in Brazil.
Zero-deforestation supply chain policies that leverage the market power of commodity buyers to change agricultural producer behavior can reduce forest clearing in regions with rapid commodity expansion and weak forest...
Biological and clinical characteristics of gene carriers far from predicted onset in the Huntington's disease Young Adult Study (HD-YAS)
Rachael I Scahill, Paul Zeun, Katherine Osborne-Crowley, Eileanoir B Johnson, Sarah Gregory, Christopher Parker, Jessica Lowe, Akshay Nair, Claire O'Callaghan, Christelle Langley, Marina Papoutsi, Peter McColgan, Carlos Estevez-Fraga, Kate Fayer, Henny Wellington, Filipe B Rodrigues, Lauren M Byrne, Amanda Heselgrave, Harpreet Hyare, Cristina Sampaio, Henrik Zetterberg, Hui Zhang, Edward J Wild, Geraint Rees, Trevor W Robbins, Barbara J Sahakian, Douglas Langbehn, Sarah J Tabrizi
Jun 22, 2020
BACKGROUND: Disease-modifying treatments are in development for Huntington's disease; crucial to their success is to identify a timepoint in a patient's life when there is a measurable biomarker of early neurodegeneration while...
Parenting and child mental health.
UNLABELLED: This paper reviews parenting programmes and their effectiveness with families of young children and highlights additional resources for primary care practitioners. Typically, 30% of GP consultations concern child...
From JWH-018 to OXIZIDS
With new synthetic cannabinoids (SCs) appearing on the European drug market every year, early warning systems are key to detect, monitor, and respond to threats posed by them. The European Union Early Warning System (EU EWS)...
European drug market drug detection early warning system new psychoactive substances synthetic cannabinoids /dk/atira/pure/subjectarea/asjc/1600/1602 name=Analytical Chemistry /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/3000/3003 name=Pharmaceutical Science /dk/atira/pure/subjectarea/asjc/1600/1607 name=Spectroscopy /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Neophobia and innovation in Critically Endangered Bali myna, Leucopsar rothschildi.
Behavioural flexibility can impact on adaptability and survival, particularly in today's changing world, and encompasses associated components like neophobia, e.g. responses to novelty, and innovation, e.g. problem-solving. Bali...
From JWH-018 to OXIZIDS
With new synthetic cannabinoids (SCs) appearing on the European drug market every year, early warning systems are key to detect, monitor, and respond to threats posed by them. The European Union Early Warning System (EU EWS)...
European drug market drug detection early warning system new psychoactive substances synthetic cannabinoids /dk/atira/pure/subjectarea/asjc/1600/1602 name=Analytical Chemistry /dk/atira/pure/subjectarea/asjc/2300/2304 name=Environmental Chemistry /dk/atira/pure/subjectarea/asjc/3000/3003 name=Pharmaceutical Science /dk/atira/pure/subjectarea/asjc/1600/1607 name=Spectroscopy /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Loss of the chromatin modifier Kdm2aa causes BrafV600E-independent spontaneous melanoma in zebrafish.
Catherine M Scahill, Zsofia Digby, Ian M Sealy, Sonia Wojciechowska, Richard J White, John E Collins, Derek L Stemple, Till Bartke, Marie E Mathers, E Elizabeth Patton, Elisabeth M Busch-Nentwich
Jun 20, 2018
KDM2A is a histone demethylase associated with transcriptional silencing, however very little is known about its in vivo role in development and disease. Here we demonstrate that loss of the orthologue kdm2aa in zebrafish causes...
Animals DNA Replication Disease Models Animal Epigenesis Genetic Exome Female Gene Expression Profiling Gene Expression Regulation Neoplastic Gene Knockout Techniques Jumonji Domain-Containing Histone Demethylases Male Melanoma Mutation Proto-Oncogene Proteins B-raf RNA Messenger Sequence Analysis RNA Zebrafish Zebrafish Proteins
Carlsberg alibi marketing in the UEFA euro 2016 football finals
Background: Alcohol advertising is a key driver of alcohol consumption, and is prohibited in France by the Loi Evin. In 2016 the Danish brewer Carlsberg sponsored the UEFA Euro 2016 finals, held in France, and used the alibis...
Waiting for the better reward
Delay of gratification-a form of self-control-is the ability to forsake immediately available rewards in order to obtain larger-valued outcomes in future, which develops throughout the pre-school years. The majority of previous...
Population exposure to smoking and tobacco branding in the UK reality show Love Island'
Alexander B. Barker, Magdalena Opazo-Breton, Joanne Cranwell, John Britton, Rachael L. Murray
Feb 05, 2018
Background Reality television shows are popular with children and young adults; inclusion of tobacco imagery in these programmes is likely to cause smoking in these groups. Series 3 of the UK reality show Love Island...
Advertising and Promotion Media Priority/special populations /dk/atira/pure/subjectarea/asjc/3300/3306 name=Health(social science) /dk/atira/pure/subjectarea/asjc/2700/2739 name=Public Health, Environmental and Occupational Health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Longitudinal touchscreen use across early development is associated with faster exogenous and reduced endogenous attention control
Childhood screen time is associated with both attentional difficulties (for television viewing) and benefits (in action video gamers), but few studies have investigated today’s pervasive touchscreen devices (e.g. smartphones and...
Current and emerging therapeutic approaches for T-cell acute lymphoblastic leukaemia.
leukaemia novel treatments Antineoplastic Agents Antineoplastic Agents Immunological Apoptosis Arabinonucleosides Bridged Bicyclo Compounds Heterocyclic Cyclin-Dependent Kinases Genetic Heterogeneity Humans Immunotherapy Immunotherapy Adoptive Janus Kinase Inhibitors Molecular Targeted Therapy Neoplasm Proteins Phosphoinositide-3 Kinase Inhibitors Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Protein Kinase Inhibitors Protein-Tyrosine Kinases Receptor Notch1 Receptors Interleukin-7 Salvage therapy Signal Transduction Sulfonamides therapies Investigational Treatment Outcome
A novel setup for simultaneous two-photon functional imaging and precise spectral and spatial visual stimulation in Drosophila.
Motion vision has been extensively characterised in Drosophila melanogaster, but substantially less is known about how flies process colour, or how spectral information affects other visual modalities. To accurately dissect the...
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