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IN MEMORY OF RALPH M. STEINMAN
The Rockefeller University
Jan 01, 0001
A Scientific Symposium in Memory of Ralph M. Steinman
See Steinman, Ralph M.
Published by: The Rockefeller University
Ralph M. Steinman: Research and Career
General information about Dr. Ralph Steinman and his Nobel Prize winning research.
Published by: Rockefeller University
Obituary. Charles Robin LeSueur, 1923-2004
Ralph D. Arcari
Jan 01, 0001
Ralph D. Arcari. Charles Robin LeSueur, 1923-2004. Journal of the Medical Library Association, 2005 Apr; 93(2): 300-302
Published by: Medical Library Association
Glycolysis promotes caspase-3 activation in lipid rafts in T cells.
Michael A Secinaro, Karen A Fortner, Oliver Dienz, Angela Logan, Michael P Murphy, Vikas Anathy, Jonathan E Boyson, Ralph C Budd
Jun 12, 2018
Resting T cells undergo a rapid metabolic shift to glycolysis upon activation in the presence of interleukin (IL)-2, in contrast to oxidative mitochondrial respiration with IL-15. Paralleling these different metabolic states are...
Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL- lpr mice
Targeted modification of the Per2 clock gene alters circadian function in mPer2luciferase (mPer2Luc) mice.
Martin R Ralph, Shu-Qun Shi, Carl H Johnson, Pavel Houdek, Tenjin C Shrestha, Priya Crosby, John S O'Neill, Martin Sládek, Adam R Stinchcombe, Alena Sumová
Jul 21, 2021
Modification of the Per2 clock gene in mPer2Luc reporter mice significantly alters circadian function. Behavioral period in constant dark is lengthened, and dissociates into two distinct components in constant light. Rhythms...
On the appearance of nitrite anion in [PdX(OAc)L<sub>2</sub>] and [Pd(X)(C∧N)L] syntheses (X = OAc or NO<sub>2</sub>)
S E Bajwa, T E Storr, Lauren E Hatcher, T J Williams, C G Baumann, A C Whitwood, D R Allan, S J Teat, Paul R Raithby, I J S Fairlamb
May 01, 2012
Pd 3(OAc) 5NO 2, an impurity in "Pd(OAc) 2" {formally Pd 3(OAc) 6}, emerges as a serious issue in the synthesis of pure Pd II complexes derived from Pd(OAc) 2, for example in our C-H activation precatalyst, Pd(OAc) 2(pip) 2 (pip...
Bridging pre-surgical endocrine therapy for breast cancer during the COVID-19 pandemic
Rajiv V Dave, Beatrix Elsberger, Vicky P Taxiarchi, Ashu Gandhi, Cliona C Kirwan, Baek Kim, Elizabeth M Camacho, Charlotte E Coles, Ellen Copson, Alona Courtney, Kieran Horgan, Patricia Fairbrother, Chris Holcombe, Jamie J Kirkham, Daniel R Leff, Stuart A McIntosh, Rachel O'Connell, Ricardo Pardo, Shelley Potter, Tim Rattay, Nisha Sharma, Raghavan Vidya, Ramsey I Cutress, B-MaP-C study collaborative
Apr 17, 2023
PURPOSE: The B-MaP-C study investigated changes to breast cancer care that were necessitated by the COVID-19 pandemic. Here we present a follow-up analysis of those patients commenced on bridging endocrine therapy (BrET), whilst...
On the appearance of nitrite anion in [PdX(OAc)L<sub>2</sub>] and [Pd(X)(C∧N)L] syntheses (X = OAc or NO<sub>2</sub>)
S E Bajwa, T E Storr, Lauren E Hatcher, T J Williams, C G Baumann, A C Whitwood, D R Allan, S J Teat, Paul R Raithby, I J S Fairlamb
May 01, 2012
Pd 3(OAc) 5NO 2, an impurity in "Pd(OAc) 2" {formally Pd 3(OAc) 6}, emerges as a serious issue in the synthesis of pure Pd II complexes derived from Pd(OAc) 2, for example in our C-H activation precatalyst, Pd(OAc) 2(pip) 2 (pip...
Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL- lpr mice
Targeting mitochondrial oxidative stress with MitoQ reduces NET formation and kidney disease in lupus-prone MRL-lpr mice.
Karen A Fortner, Luz P Blanco, Iwona Buskiewicz, Nick Huang, Pamela C Gibson, Deborah L Cook, Hege L Pedersen, Peter ST Yuen, Michael P Murphy, Andras Perl, Mariana J Kaplan, Ralph C Budd
Jun 05, 2020
OBJECTIVES: Recent investigations in humans and mouse models with lupus have revealed evidence of mitochondrial dysfunction and production of mitochondrial reactive oxygen species (mROS) in T cells and neutrophils. This can...
T cells Autoimmune Diseases Inflammation Systemic Lupus Erythematosus Animals Autoantibodies Disease Models Animal Extracellular Traps Female Humans Interferon Type I Kidney Kidney Diseases Lupus Erythematosus Systemic Male Mice Mice Inbred MRL lpr Mitochondria Neutrophils Organophosphorus Compounds Oxidation-Reduction Oxidative Stress Reactive Oxygen Species T-Lymphocytes Ubiquinone
Global blow-up for a semilinear heat equation on a subspace
We study the asymptotic behaviour as t → T–, near a finite blow-up time T > 0, of decreasing-in-x solutions to the following semilinear heat equation with a non-local term:(Figure presented.) with Neumann...
Circulating vitamin C and digestive system cancers
Susanna C Larsson, Amy M Mason, Mathew Vithayathil, Paul Carter, Siddhartha Kar, Ju-Sheng Zheng, Stephen Burgess
Sep 20, 2022
BACKGROUND & AIMS: Vitamin C is an antioxidant with a potential role in the prevention of digestive system cancers, but there is yet no consensus whether vitamin C has a causal role in these cancers. The aim of this study was to...
Breast cancer management pathways during the COVID-19 pandemic
Rajiv V Dave, Baek Kim, Alona Courtney, Rachel O'Connell, Tim Rattay, Vicky P Taxiarchi, Jamie J Kirkham, Elizabeth M Camacho, Patricia Fairbrother, Nisha Sharma, Christopher WJ Cartlidge, Kieran Horgan, Stuart A McIntosh, Daniel R Leff, Raghavan Vidya, Shelley Potter, Chris Holcombe, Ellen Copson, Charlotte E Coles, Ramsey I Cutress, Ashu Gandhi, Cliona C Kirwan, B-MaP-C study collaborative
Apr 14, 2021
BACKGROUND: The B-MaP-C study aimed to determine alterations to breast cancer (BC) management during the peak transmission period of the UK COVID-19 pandemic and the potential impact of these treatment decisions. METHODS: This...
Selective iodination and polypeptide composition of pinocytic vesicles
We describe a method for the specific radioiodination of pinocytic vesicles (PVs) based upon the simultaneous endocytosis of lactoperoxidase (LPO) and glucose oxidase (GO). Initial experiments indicated that LPO was interiorized...
Published by: Rockefeller University
The ALPINE–ALMA [C ii] Survey
Abstract
We present the radio properties of 66 spectroscopically confirmed normal star-forming galaxies (SFGs) at 4.4 < z < 5.9 in the COSMOS field...
Lu Shen, Brian C Lemaux, Lori M Lubin, Guilin Liu, Matthieu Béthermin, Médéric Boquien, Olga Cucciati, Olivier Le Fèvre, Margherita Talia, Daniela Vergani, Gianni Zamorani, Andreas L Faisst, Michele Ginolfi, Carlotta Gruppioni, Gareth C Jones, Sandro Bardelli, Nimish Hathi, Anton M Koekemoer, Michael Romano, Daniel Schaerer, Elena Zucca, Wenjuan Fang, Ben Forrest, Roy Gal, Denise Hung, Ekta A Shah, Priti Staab, Brittany Vanderhoof, Eduardo Ibar
Aug 24, 2022
Upgrading biogenic furans
Benzaldehyde lyase (BAL) results in an efficient biocatalyst for theumpolung carboligation of furfural, HMF, and mixtures of them,leading to blended C10–C12 platform chemicals. Subsequently, themixing and...
Upgrading biogenic furans
Benzaldehyde lyase (BAL) results in an efficient biocatalyst for theumpolung carboligation of furfural, HMF, and mixtures of them,leading to blended C10–C12 platform chemicals. Subsequently, themixing and...
Asymptotical computations for a model of flow in saturated porous media
We discuss an initial value problem for an implicit second order ordinary differential equation which arises in models of flow in saturated porous media such as concrete. Depending on the initial condition, the solution features...
Asymptotical computations for a model of flow in saturated porous media
We discuss an initial value problem for an implicit second order ordinary differential equation which arises in models of flow in saturated porous media such as concrete. Depending on the initial condition, the solution features...
Dendritic cells are accessory cells for the development of anti-trinitrophenyl cytotoxic T lymphocytes
This study establishes that dendritic cells (DC) are the critical accessory cells for the development of anti-trinitrophenol (TNP) cytotoxic T lymphocytes (CTL) in vitro. We developed a model in which nylon wool-nonadherent...
Published by: Rockefeller University
Global blow-up for a semilinear heat equation on a subspace
We study the asymptotic behaviour as t → T–, near a finite blow-up time T > 0, of decreasing-in-x solutions to the following semilinear heat equation with a non-local term:(Figure presented.) with Neumann...
Search for the doubly heavy baryons Ω<inf>bc</inf><sup>0</sup>and Ξ<inf>bc</inf><sup>0</sup>decaying to Λ<inf>c</inf><sup>+</sup>π- And Ξ<inf>c</inf><sup>+</sup>π- And c
C Nguyen-Mau, R Aaij, C Abellán Beteta, T Ackernley, B Adeva, M Adinolfi, H Afsharnia, CA Aidala, S Aiola, Z Ajaltouni, S Akar, J Albrecht, F Alessio, M Alexander, A Alfonso Albero, Z Aliouche, G Alkhazov, P Alvarez Cartelle, S Amato, Y Amhis, L An, L Anderlini, A Andreianov, M Andreotti, F Archilli, A Artamonov, M Artuso, K Arzymatov, E Aslanides, M Atzeni, B Audurier, S Bachmann, M Bachmayer, JJ Back, P Baladron Rodriguez, V Balagura, W Baldini, J Baptista Leite, RJ Barlow, S Barsuk, W Barter, M Bartolini, F Baryshnikov, JM Basels, G Bassi, B Batsukh, A Battig, A Bay, M Becker, F Bedeschi, I Bediaga, A Beiter, V Belavin, S Belin, V Bellee, K Belous, I Belov, I Belyaev, G Bencivenni, E Ben-Haim, A Berezhnoy, R Bernet, D Berninghoff, HC Bernstein, C Bertella, A Bertolin, C Betancourt, F Betti, I Bezshyiko, S Bhasin, J Bhom, L Bian, MS Bieker, S Bifani, P Billoir, M Birch, FCR Bishop, A Bitadze, A Bizzeti, M Bj rn, MP Blago, T Blake, F Blanc, S Blusk, D Bobulska, JA Boelhauve, O Boente Garcia, T Boettcher, A Boldyrev, A Bondar, N Bondar, S Borghi, M Borisyak, M Borsato, JT Borsuk, SA Bouchiba, TJV Bowcock, A Boyer, C Bozzi, MJ Bradley
Aug 31, 2021
The first search for the doubly heavy $\it{\Omega}_{bc}^{\rm0}$ baryon and a
search for $\it{\Xi}_{bc}^{\rm0}$ baryon are performed using $pp$ collision
data collected via the LHCb experiment from 2016 to 2018 at a...
Selective Dealkenylative Functionalization of Styrenes via C-C Bond Cleavage.
As a readily available feedstock, styrene with about 25 million tons of global annual production serves as an important building block and organic synthon for the synthesis of fine chemicals, polystyrene plastics, and...
New C∧N∧C Bis-Cyclometalated Platinum(II) Complexes
Sara Fuertes Lorda, Simon K Brayshaw, Paul R Raithby, Stefanie Schiffers, Mark R Warren
Jan 01, 0001
The reaction of a new ligand, ethyl 2,6-diphenylisonicotinate (EtO(2)C-CAN boolean AND C-H(2)), with K(2)PtCl(4) in acetic acid affords the monocyclometalated complex [{(EtO(2)C-CANAC-H)Pt(mu-Cl)}(2)] (1), which transforms to...
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