Search

Results: 130
Three Board of Trustee Candidates Elected by S.C. General Assembly
Winthrop University
Jan 01, 0001
Donna Glenn Holley of Congressional District 2 and Ashlye Wilkerson `05 of Congressional District 6 were re-elected on April 2. Randy Imler `87, `00 will replace long-time member Bob Thompson in the at-large seat, which was...
Published by: Winthrop University
Law Enforcement and Military Members
This chapter seeks to assist law enforcement by providing an empirical review of research on the relationship between military service and risk of dangerousness—to self (suicide) or others (violent crime). Risk posed by military...
Case-controlled structure validation.
Although many factors influence the quality of a macromolecular crystal structure, validation criteria are usually only calibrated using one of these factors, the resolution. For many purposes this is sufficient, but there are...
Published by:
Dendritic Cells Mediate the Dual Effects of IFN alpha/beta in HCV Immunity
Randy Longman
Jan 01, 0001
Hepatitis C virus (HCV) infects an estimated 170 million people and is responsible for considerable morbidity and mortality worldwide. Successful resolution of infection is achieved naturally in approximately 30% of infected...
Published by: Rockefeller University
Improvement of molecular-replacement models with Sculptor.
In molecular replacement, the quality of models can be improved by transferring information contained in sequence alignment to the template structure. A family of algorithms has been developed that make use of the...
Published by:
Law Enforcement and Military Members
This chapter seeks to assist law enforcement by providing an empirical review of research on the relationship between military service and risk of dangerousness—to self (suicide) or others (violent crime). Risk posed by military...
Evaluating parameters affecting drug fate at the intramuscular injection site
Intramuscular (IM) injections are a well-established method of delivering a variety of therapeutics formulated for parenteral administration. While the wide range of commercial IM pharmaceuticals provide a wealth of...
Published by:
Structural basis for the specificity of renin-mediated angiotensinogen cleavage.
The renin-angiotensin cascade is a hormone system that regulates blood pressure and fluid balance. Renin-mediated cleavage of the angiotensin I peptide from the N terminus of angiotensinogen (AGT) is the rate-limiting step of...
Published by:
Angiotensinogen and the Modulation of Blood Pressure.
The angiotensin peptides that control blood pressure are released from the non-inhibitory plasma serpin, angiotensinogen, on cleavage of its extended N-terminal tail by the specific aspartyl-protease, renin. Angiotensinogen had...
Published by:
Maximum-likelihood determination of anomalous substructures.
A fast Fourier transform (FFT) method is described for determining the substructure of anomalously scattering atoms in macromolecular crystals that allows successful structure determination by X-ray single-wavelength anomalous...
Published by:
Experimental phasing
Developments in protein crystal structure determination by experimental phasing are reviewed, emphasizing the theoretical continuum between experimental phasing, density modification, model building and refinement. Traditional...
Published by:
Adaptive Cartesian and torsional restraints for interactive model rebuilding.
When building atomic models into weak and/or low-resolution density, a common strategy is to restrain their conformation to that of a higher resolution model of the same or similar sequence. When doing so, it is important to...
Published by:
Evaluating parameters affecting drug fate at the intramuscular injection site
Intramuscular (IM) injections are a well-established method of delivering a variety of therapeutics formulated for parenteral administration. While the wide range of commercial IM pharmaceuticals provide a wealth of...
Published by:
Using SAD data in Phaser.
Phaser is a program that implements likelihood-based methods to solve macromolecular crystal structures, currently by molecular replacement or single-wavelength anomalous diffraction (SAD). SAD phasing is based on a likelihood...
Published by:
The Impact of Mitochondrial Fission-Stimulated ROS Production on Pro-Apoptotic Chemotherapy.
Cancer is one of the world's deadliest afflictions. Despite recent advances in diagnostic and surgical technologies, as well as improved treatments of some individual tumor types, there is currently no universal cure to prevent...
Published by:
Improved estimates of coordinate error for molecular replacement.
The estimate of the root-mean-square deviation (r.m.s.d.) in coordinates between the model and the target is an essential parameter for calibrating likelihood functions for molecular replacement (MR). Good estimates of the...
Published by:
Measuring and using information gained by observing diffraction data.
The information gained by making a measurement, termed the Kullback-Leibler divergence, assesses how much more precisely the true quantity is known after the measurement was made (the posterior probability distribution) than...
Published by:
Winthrop Community Hunger Action Awareness Initiatives, 1970s -Present
This panel looks at Winthrop University and the greater Rock Hill Community's efforts to deal with food insecurity locally and globally from the 1970s to the present.
Published by: Winthrop University
Nisotak
This paper outlines the design, development, and preliminary usability study of a system comprising 1) a web-based Indigenous lesson-creation interface and 2) an accompanying mobile app for studying the lessons. The Nisotak...
The Impact of Mitochondrial Fission-Stimulated ROS Production on Pro-Apoptotic Chemotherapy
Cancer is one of the world’s deadliest afflictions. Despite recent advances in diagnostic and surgical technologies, as well as improved treatments of some individual tumor types, there is currently no universal cure to prevent...
Published by:
Law Enforcement and Military Members
This chapter seeks to assist law enforcement by providing an empirical review of research on the relationship between military service and risk of dangerousness—to self (suicide) or others (violent crime). Risk posed by military...

|<

<

1

2

3

4

5

>

>|