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ROBERT DARNELL AND TITIA DE LANGE
The Rockefeller University
Jan 01, 0001
Robert Darnell and Titia de Lange have been elected to the Institute of Medicine
Published by: The Rockefeller University
B-hadron production in NNLO QCD
We calculate, for the first time, the NNLO QCD corrections to identified
heavy hadron production at hadron colliders. The calculation is based on a
flexible numeric framework which allows the calculation of any distribution of
a...
Robert Steen Kledal to Give M.B.A. Lecture Oct. 3
Winthrop University
Jan 01, 0001
Robert Steen Kledal, senior VP of Maersk, Inc., will deliver the M.B.A. lecture on Oct. 3. A native of Denmark, Kledal has worked for Maersk since 1990.
Published by: Winthrop University
Restriction endonuclease TseI cleaves A:A and T
Long Ma, Kai Chen, David J Clarke, Christopher P Nortcliffe, Geoffrey G Wilson, J Michael Edwardson, A Jennifer Morton, Anita C Jones, David TF Dryden
Feb 13, 2020
The type II restriction endonuclease TseI recognizes the DNA target sequence 5'-G^CWGC-3' (where W = A or T) and cleaves after the first G to produce fragments with three-base 5'-overhangs. We have determined that it is a...
A Simple Method for Measuring Fine-to-Ultrafine Aerosols Using Bipolar Charge Equilibrium.
Robert T Nishida, Tyler J Johnson, Joshua S Hassim, Brian M Graves, Adam M Boies, Simone Hochgreb
Jan 15, 2020
Low-cost methods for measuring airborne microparticles and nanoparticles (aerosols) have remained elusive despite the increasing concern of health impacts from ambient, urban, and indoor sources. While bipolar ion sources are...
Viral load of SARS-CoV-2 in droplets and bioaerosols directly captured during breathing, speaking and coughing.
Tyler J Johnson, Robert T Nishida, Ashlesha P Sonpar, Yi-Chan James Lin, Kimberley A Watson, Stephanie W Smith, John M Conly, David H Evans, Jason S Olfert
Apr 03, 2022
Determining the viral load and infectivity of SARS-CoV-2 in macroscopic respiratory droplets, bioaerosols, and other bodily fluids and secretions is important for identifying transmission modes, assessing risks and informing...
Interview with Booker T. Brown - OH 689
This interview was conducted by Dr. George Garrison with Booker T. Brown with a focus on the History of Emmett Scott High School. Emmett Scott was the segregated high school for African-Americans, which was named after Emmett...
Published by: Winthrop University
Shear Capacity of Reinforced Concrete T-Beams Retrofit with Externally Bonded CFRP Fabric
Unanchored U-wrapped externally bonded carbon-fiber-reinforced polymer (CFRP) fabrics are widely used to increase the design shear strength of existing reinforced concrete slab-on-beam structures, but current design models do...
Comprehensive characterization of mainstream marijuana and tobacco smoke
Brian M. Graves, Tyler J. Johnson, Robert T. Nishida, Ryan P. Dias, Benjamin Savareear, James J. Harynuk, Mohsen Kazemimanesh, Jason S. Olfert, Adam M. Boies
Apr 28, 2021
Abstract: Recent increases in marijuana use and legalization without adequate knowledge of the risks necessitate the characterization of the billions of nanoparticles contained in each puff of smoke. Tobacco smoke offers a...
PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4 + T Cells
Daisy H. Luff, Katarzyna Wojdyla, David Oxley, Tamara Chessa, Kevin Hudson, Phillip T. Hawkins, Len R. Stephens, Simon T. Barry, Klaus Okkenhaug
Mar 22, 2021
Phosphoinositide 3-kinases (PI3Ks) play a central role in adaptive immunity by transducing signals from the T cell antigen receptor (TCR) via production of PIP3. PI3Kδ is a heterodimer composed of a p110δ catalytic subunit...
PI3Kδ Forms Distinct Multiprotein Complexes at the TCR Signalosome in Naïve and Differentiated CD4+ T Cells.
Daisy H Luff, Katarzyna Wojdyla, David Oxley, Tamara Chessa, Kevin Hudson, Phillip T Hawkins, Len R Stephens, Simon T Barry, Klaus Okkenhaug
Feb 03, 2021
Phosphoinositide 3-kinases (PI3Ks) play a central role in adaptive immunity by transducing signals from the T cell antigen receptor (TCR) via production of PIP3. PI3Kδ is a heterodimer composed of a p110δ catalytic subunit...
CD4-Positive T-Lymphocytes Animals Mice Inbred C57BL Mice Multiprotein Complexes Receptors Antigen T-Cell Interleukin-2 Lymphocyte Activation Specific Pathogen-Free Organisms Signal Transduction Cell Differentiation Gene Knockout Techniques Class I Phosphatidylinositol 3-Kinases CRISPR-Cas Systems Gene Editing
Revolutions in the head
James A Secord
Dec 18, 2020
The late 1960s witnessed a key conjunction between political activism and the history of science. Science, whether seen as a touchstone of rationality or of oppression, was fundamental to all sides in the era of the Vietnam War....
Extracellular Lactate
James T Grist, Lorna B Jarvis, Zoya Georgieva, Sara Thompson, Harpreet Kaur Sandhu, Keith Burling, Ashley Clarke, Sarah Jackson, Mark Wills, Ferdia A Gallagher, Joanne L Jones
Feb 23, 2018
Following activation, T cells rapidly divide and acquire effector functions. This energetically demanding process depends upon the ability of T cells to undergo metabolic remodeling from oxidative phosphorylation to aerobic...
T Lymphocytes in Histiocytic Sarcomas of Flat-Coated Retriever Dogs.
Flat-Coated Retriever dogs are predisposed to the development of histiocytic sarcoma (HS), a poorly differentiated, highly malignant neoplasm. The authors have previously documented a significant lymphocytic infiltrate in such...
Spotlight on deep carbon research.
Professor Marie Edmonds is a volcanologist at the University of Cambridge. She is interested in the role of magmatic volatiles in magma genesis, volcanic eruptions, and volatile geochemical cycling. Dr. Robert Hazen is a...
The Influence of Electrolytes on the Solution and Precipitation of Casein and Gelatin
Jacques Loeb and Robert E. Loeb. The influence of electrolytes on the solution and precipitation of casein and gelatin
Reprinted from J. Gen. Physiol., 1921, 4(2):187-211
Published by: The Rockefeller University Press
High fidelity analysis to predict failure in T-joints
Composite T-joints and similar skin-stiffener joints have a central role in aerospace structures. However, their accurate numerical analysis is still a great challenge due to their complex geometry and stress state during...
The microRNA miR-155 controls CD8(+) T cell responses by regulating interferon signaling.
Donald T Gracias, Erietta Stelekati, Jennifer L Hope, Alina C Boesteanu, Travis A Doering, Jillian Norton, Yvonne M Mueller, Joseph A Fraietta, E John Wherry, Martin Turner, Peter D Katsikis
Aug 14, 2019
We found upregulation of expression of the microRNA miR-155 in primary effector and effector memory CD8(+) T cells, but low miR-155 expression in naive and central memory cells. Antiviral CD8(+) T cell responses and viral...
Animals CD8-Positive T-Lymphocytes Cell Proliferation Flow Cytometry Gene Expression Profiling Gene Regulatory Networks Immunoblotting Immunologic Memory Interferon Regulatory Factor-7 Interferons Mice Mice Inbred C57BL Mice Knockout MicroRNAs Oligonucleotide Array Sequence Analysis Orthomyxoviridae Orthomyxoviridae Infections RNA Interference Reverse Transcriptase Polymerase Chain Reaction STAT1 Transcription Factor Signal Transduction Suppressor of Cytokine Signaling 1 Protein Suppressor of Cytokine Signaling Proteins
High fidelity analysis to predict failure in T-joints
Composite T-joints and similar skin-stiffener joints have a central role in aerospace structures. However, their accurate numerical analysis is still a great challenge due to their complex geometry and stress state during...
A Sphingosine 1-Phosphate Gradient Is Linked to the Cerebral Recruitment of T Helper and Regulatory T Helper Cells during Acute Ischemic Stroke.
Alexandra Lucaciu, Hannah Kuhn, Sandra Trautmann, Nerea Ferreirós, Helmuth Steinmetz, Josef Pfeilschifter, Robert Brunkhorst, Waltraud Pfeilschifter, Julien Subburayalu, Rajkumar Vutukuri
Aug 29, 2020
Emerging evidence suggests a complex relationship between sphingosine 1-phosphate (S1P) signaling and stroke. Here, we show the kinetics of S1P in the acute phase of ischemic stroke and highlight accompanying changes in immune...
Ceramides fingolimod regulatory T helper cells sphingosine 1-phosphate sphingosine 1-phosphate receptor sphingosine kinase stroke Animals Brain Disease Models Animal ischemic stroke Lysophospholipids Male Mice Mice Inbred C57BL Signal Transduction Sphingosine Sphingosine-1-Phosphate Receptors Spleen T-Lymphocytes Helper-Inducer T-Lymphocytes Regulatory
Adaptive Skill as The<i> Conditio Sine Qua Non</i> of Expertise
This critical interpretive research synthesis is on the topic of adaptation and skill. After an initial identification of 1995 abstracts we identified and collated a database of 140 publications that explicitly reference...
A Doctor of Another Facultie
Esther Osorio Whewell
Mar 06, 2020
Despite having written hundreds of Spenserian stanzas, appearing in multiple volumes of divine poetry throughout the mid-seventeenth century, ecclesiastical lawyer Robert Aylett has been little remarked by Spenser scholars. His...
An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression.
Asis Palazon, Petros A Tyrakis, David Macias, Pedro Veliça, Helene Rundqvist, Susan Fitzpatrick, Nikola Vojnovic, Anthony T Phan, Niklas Loman, Ingrid Hedenfalk, Thomas Hatschek, John Lövrot, Theodoros Foukakis, Ananda W Goldrath, Jonas Bergh, Randall S Johnson
May 31, 2018
Cytotoxic T cells infiltrating tumors are thought to utilize HIF transcription factors during adaptation to the hypoxic tumor microenvironment. Deletion analyses of the two key HIF isoforms found that HIF-1α, but not HIF-2α, was...
HIF transcription factors VEGF angiogenesis cytotoxic T cells Hypoxia Immunotherapy Animals Breast Neoplasms CD8-Positive T-Lymphocytes Cell Line Tumor Cells Cultured Disease Progression Female Gene Expression Profiling Gene Expression Regulation Neoplastic Humans Hypoxia-Inducible Factor 1 alpha Subunit Mice Inbred C57BL Mice Knockout Neoplasms Experimental Neovascularization Pathologic T-Lymphocytes Cytotoxic Vascular Endothelial Growth Factor A
The Lantern Vol. 19, No. 1, Winter 1951
Caroline Herber, William LeKernec, Lou Cresse, Robert N. Jordan, Jr., E. A. Chambers, Carl Donne Young, Sally Canan, David Hallstrom, Joan Sapp, Aubre Givler, Emile Schmidt
Jan 01, 0001
Nevin LaRue There Stands a Wall An Iron God Little Reginald and the Goat Tale The Atom After Dark Lament To Tell Me Eight-Fifteen After Reading Robert Frost New Era Eternity Recollection Two Poems
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Korea Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
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