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Results: 740
Automatic analysis (aa)
Rhodri Cusack, Alejandro Vicente-Grabovetsky, Daniel J Mitchell, Conor J Wild, Tibor Auer, Annika C Linke, Jonathan E Peelle
Jun 26, 2018
Recent years have seen neuroimaging data sets becoming richer, with larger cohorts of participants, a greater variety of acquisition techniques, and increasingly complex analyses. These advances have made data analysis pipelines...
The value of sorafenib trough levels in patients with advanced hepatocellular carcinoma - a substudy of the SORAMIC trial.
Tim A Labeur, Quincy Hofsink, R Bart Takkenberg, Otto M van Delden, Ron AA Mathôt, Regina Schinner, Peter Malfertheiner, Holger Amthauer, Kerstin Schütte, Bristi Basu, Christiane Kuhl, Julia Mayerle, Jens Ricke, Heinz-Josef Klümpen
May 11, 2020
Background: Sorafenib for advanced hepatocellular carcinoma (HCC) is dose adjusted by toxicity. Preliminary studies have suggested an association between plasma concentrations of sorafenib and its main metabolite (M2) and...
hepatocellular carcinoma Pharmacokinetics Sorafenib survival toxicity Aged Antineoplastic Agents Carcinoma Hepatocellular Dose-Response Relationship Drug Drug-Related Side Effects and Adverse Reactions Female Humans Incidence Kaplan-Meier Estimate Liver Neoplasms Male Middle Aged Neoplasm Staging Prospective Studies Reference Values Severity of Illness Index Sorafenib
Drawing attention to a neglected injecting‐related harm
Magdalena Harris, Rachel Brathwaite, Jennifer Scott, Gail Gilchrist, Dan Ciccarone, Vivian Hope, Catherine R. McGowan
Oct 01, 2018
Background and Aims: Chronic skin and soft tissue infections (SSTI) among people who inject drugs (PWID) can lead to AA amyloidosis: a serious, yet neglected, multi-organ disease. We aim to synthesize findings on the...
AA amyloidosis Kidney Disease people who inject drugs skin and soft tissue infections Subcutaneous injection Systematic review /dk/atira/pure/subjectarea/asjc/2700/2701 name=Medicine (miscellaneous) /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Drawing attention to a neglected injecting‐related harm
Magdalena Harris, Rachel Brathwaite, Jennifer Scott, Gail Gilchrist, Dan Ciccarone, Vivian Hope, Catherine R. McGowan
Oct 01, 2018
Background and Aims: Chronic skin and soft tissue infections (SSTI) among people who inject drugs (PWID) can lead to AA amyloidosis: a serious, yet neglected, multi-organ disease. We aim to synthesize findings on the...
AA amyloidosis Kidney Disease people who inject drugs skin and soft tissue infections Subcutaneous injection Systematic review /dk/atira/pure/subjectarea/asjc/2700/2701 name=Medicine (miscellaneous) /dk/atira/pure/subjectarea/asjc/2700/2738 name=Psychiatry and Mental health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Abdominal versus perineal approach for external rectal prolapse
Gianluca Pellino, Giacomo Fuschillo, Costantinos Simillis, Lucio Selvaggi, Giuseppe Signoriello, Danilo Vinci, Christos Kontovounisios, Francesco Selvaggi, Guido Sciaudone
May 09, 2022
BACKGROUND: External rectal prolapse (ERP) is a debilitating condition in which surgery plays an important role. The aim of this study was to evaluate the outcomes of abdominal approaches (AA) and perineal approaches (PA) to...
Diagnosis and treatment of acute appendicitis
Salomone Di Saverio, Mauro Podda, Belinda De Simone, Marco Ceresoli, Goran Augustin, Alice Gori, Marja Boermeester, Massimo Sartelli, Federico Coccolini, Antonio Tarasconi, Nicola de’ Angelis, Dieter G. Weber, Matti Tolonen, Arianna Birindelli, Walter Biffl, Ernest E. Moore, Michael Kelly, Kjetil Soreide, Jeffry Kashuk, Richard Ten Broek, Carlos Augusto Gomes, Michael Sugrue, Richard Justin Davies, Dimitrios Damaskos, Ari Leppäniemi, Andrew Kirkpatrick, Andrew B. Peitzman, Gustavo P. Fraga, Ronald V. Maier, Raul Coimbra, Massimo Chiarugi, Gabriele Sganga, Adolfo Pisanu, Gian Luigi de’ Angelis, Edward Tan, Harry Van Goor, Francesco Pata, Isidoro Di Carlo, Osvaldo Chiara, Andrey Litvin, Fabio C. Campanile, Boris Sakakushev, Gia Tomadze, Zaza Demetrashvili, Rifat Latifi, Fakri Abu-Zidan, Oreste Romeo, Helmut Segovia-Lohse, Gianluca Baiocchi, David Costa, Sandro Rizoli, Zsolt J. Balogh, Cino Bendinelli, Thomas Scalea, Rao Ivatury, George Velmahos, Roland Andersson, Yoram Kluger, Luca Ansaloni, Fausto Catena
Jul 23, 2020
Abstract: Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different...
Review acute appendicitis Appendicitis guidelines Jerusalem guidelines Consensus conference Alvarado score Appendicitis diagnosis score Adult Appendicitis Score Imaging CT scan appendicitis non-operative management Antibiotics Complicated appendicitis Appendectomy Laparoscopic appendectomy Diagnostic laparoscopy Phlegmon Appendiceal abscess
Pattern of arterial inflammation and inflammatory markers in people living with HIV compared with uninfected people.
Nevio Taglieri, Rachele Bonfiglioli, Isabella Bon, Pietro Malosso, Andrej Corovic, Matteo Bruno, Elizabeth Le, Bianca Granozzi, Tullio Palmerini, Gabriele Ghetti, Martina Tamburello, Antonio Giulio Bruno, Francesco Saia, Jason Tarkin, James Rudd, Leonardo Calza, Stefano Fanti, Maria Carla Re, Nazzareno Galié
Jan 04, 2021
STUDY DESIGN: To compare arterial inflammation (AI) between people living with HIV (PLWH) and uninfected people as assessed by 18F-Fluorodeoxyglucose (18F-FDG)-positron emission tomography (PET). METHODS: We prospectively...
Diagnosis and treatment of acute appendicitis
Salomone Di Saverio, Mauro Podda, Belinda De Simone, Marco Ceresoli, Goran Augustin, Alice Gori, Marja Boermeester, Massimo Sartelli, Federico Coccolini, Antonio Tarasconi, Nicola de’ Angelis, Dieter G. Weber, Matti Tolonen, Arianna Birindelli, Walter Biffl, Ernest E. Moore, Michael Kelly, Kjetil Soreide, Jeffry Kashuk, Richard Ten Broek, Carlos Augusto Gomes, Michael Sugrue, Richard Justin Davies, Dimitrios Damaskos, Ari Leppäniemi, Andrew Kirkpatrick, Andrew B. Peitzman, Gustavo P. Fraga, Ronald V. Maier, Raul Coimbra, Massimo Chiarugi, Gabriele Sganga, Adolfo Pisanu, Gian Luigi de’ Angelis, Edward Tan, Harry Van Goor, Francesco Pata, Isidoro Di Carlo, Osvaldo Chiara, Andrey Litvin, Fabio C. Campanile, Boris Sakakushev, Gia Tomadze, Zaza Demetrashvili, Rifat Latifi, Fakri Abu-Zidan, Oreste Romeo, Helmut Segovia-Lohse, Gianluca Baiocchi, David Costa, Sandro Rizoli, Zsolt J. Balogh, Cino Bendinelli, Thomas Scalea, Rao Ivatury, George Velmahos, Roland Andersson, Yoram Kluger, Luca Ansaloni, Fausto Catena
Jul 01, 2020
Abstract: Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different...
Review acute appendicitis Appendicitis guidelines Jerusalem guidelines Consensus conference Alvarado score Appendicitis diagnosis score Adult Appendicitis Score Imaging CT scan appendicitis non-operative management Antibiotics Complicated appendicitis Appendectomy Laparoscopic appendectomy Diagnostic laparoscopy Phlegmon Appendiceal abscess
Octane Appetite
Sarah Remmert, Steven Campbell, Roger Cracknell, Andrea Schuetze, Andrew Lewis, Karl Giles, Sam Akehurst, James Turner, Andrew Popplewell, Rishin Patel
Nov 30, 2014
Market demand for high performance gasoline vehicles and increasingly strict government emissions regulations are driving the development of highly downsized, boosted direct injection engines. The in-cylinder temperatures and...
Genetically predicted plasma phospholipid arachidonic acid concentrations and 10 site-specific cancers in UK biobank and genetic consortia participants
Susanna C Larsson, Paul Carter, Mathew Vithayathil, Amy M Mason, Karl Michaëlsson, John A Baron, Stephen Burgess
Nov 03, 2020
BACKGROUND & AIMS: Arachidonic acid (AA) is metabolized by cyclooxygenases and lipoxygenases to pro-inflammatory eicosanoids, which according to experimental research modulate tumor cell proliferation, differentiation, and...
Diagnosis and treatment of acute appendicitis
Salomone Di Saverio, Mauro Podda, Belinda De Simone, Marco Ceresoli, Goran Augustin, Alice Gori, Marja Boermeester, Massimo Sartelli, Federico Coccolini, Antonio Tarasconi, Nicola De' Angelis, Dieter G Weber, Matti Tolonen, Arianna Birindelli, Walter Biffl, Ernest E Moore, Michael Kelly, Kjetil Soreide, Jeffry Kashuk, Richard Ten Broek, Carlos Augusto Gomes, Michael Sugrue, Richard Justin Davies, Dimitrios Damaskos, Ari Leppäniemi, Andrew Kirkpatrick, Andrew B Peitzman, Gustavo P Fraga, Ronald V Maier, Raul Coimbra, Massimo Chiarugi, Gabriele Sganga, Adolfo Pisanu, Gian Luigi De' Angelis, Edward Tan, Harry Van Goor, Francesco Pata, Isidoro Di Carlo, Osvaldo Chiara, Andrey Litvin, Fabio C Campanile, Boris Sakakushev, Gia Tomadze, Zaza Demetrashvili, Rifat Latifi, Fakri Abu-Zidan, Oreste Romeo, Helmut Segovia-Lohse, Gianluca Baiocchi, David Costa, Sandro Rizoli, Zsolt J Balogh, Cino Bendinelli, Thomas Scalea, Rao Ivatury, George Velmahos, Roland Andersson, Yoram Kluger, Luca Ansaloni, Fausto Catena
Apr 15, 2021
BACKGROUND AND AIMS: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different settings and...
acute appendicitis Adult Appendicitis Score Alvarado score Antibiotics Appendectomy Appendiceal abscess Appendicitis diagnosis score Appendicitis guidelines CT scan appendicitis Complicated appendicitis Consensus conference Diagnostic laparoscopy Imaging Jerusalem guidelines Laparoscopic appendectomy non-operative management Phlegmon Abdominal Pain Acute Disease Anti-Bacterial Agents Appendectomy Appendicitis Evidence-Based Medicine Humans laparoscopy Practice Guidelines as Topic
Annular versus supra-annular sizing for transcatheter aortic valve replacement in bicuspid aortic valve disease.
Jonathan R Weir-McCall, Adrian Attinger-Toller, Philipp Blanke, Gidon Y Perlman, Stephanie L Sellers, David Wood, John G Webb, Jonathon Leipsic
Sep 28, 2020
BACKGROUND: CT measurement of supra-annular area (SA) has been proposed as an alternative to annular area (AA) for sizing of trancatheter valves in biscuspid aortic valves (BAV). This study examines the reproducibility of SA and...
Aortic stenosis Bicuspid aortic valve Computer tomography Tavr Valvular disease Aged Aged 80 and over Aortic Valve aortic valve stenosis Bicuspid Aortic Valve Disease Computed Tomography Angiography Coronary Angiography Echocardiography Female Heart Valve Diseases Heart valve prosthesis Humans Male Middle Aged Multidetector Computed Tomography Predictive Value of Tests Prosthesis Design Retrospective Studies Severity of Illness Index transcatheter aortic valve replacement Treatment Outcome
Higher-order phosphatase-substrate contacts terminate the integrated stress response.
Diagnosis and treatment of acute appendicitis
Salomone Di Saverio, Mauro Podda, Belinda De Simone, Marco Ceresoli, Goran Augustin, Alice Gori, Marja Boermeester, Massimo Sartelli, Federico Coccolini, Antonio Tarasconi, Nicola de’ Angelis, Dieter G. Weber, Matti Tolonen, Arianna Birindelli, Walter Biffl, Ernest E. Moore, Michael Kelly, Kjetil Soreide, Jeffry Kashuk, Richard Ten Broek, Carlos Augusto Gomes, Michael Sugrue, Richard Justin Davies, Dimitrios Damaskos, Ari Leppäniemi, Andrew Kirkpatrick, Andrew B. Peitzman, Gustavo P. Fraga, Ronald V. Maier, Raul Coimbra, Massimo Chiarugi, Gabriele Sganga, Adolfo Pisanu, Gian Luigi de’ Angelis, Edward Tan, Harry Van Goor, Francesco Pata, Isidoro Di Carlo, Osvaldo Chiara, Andrey Litvin, Fabio C. Campanile, Boris Sakakushev, Gia Tomadze, Zaza Demetrashvili, Rifat Latifi, Fakri Abu-Zidan, Oreste Romeo, Helmut Segovia-Lohse, Gianluca Baiocchi, David Costa, Sandro Rizoli, Zsolt J. Balogh, Cino Bendinelli, Thomas Scalea, Rao Ivatury, George Velmahos, Roland Andersson, Yoram Kluger, Luca Ansaloni, Fausto Catena
Jun 06, 2020
Abstract: Background and aims: Acute appendicitis (AA) is among the most common causes of acute abdominal pain. Diagnosis of AA is still challenging and some controversies on its management are still present among different...
Review acute appendicitis Appendicitis guidelines Jerusalem guidelines Consensus conference Alvarado score Appendicitis diagnosis score Adult Appendicitis Score Imaging CT scan appendicitis non-operative management Antibiotics Complicated appendicitis Appendectomy Laparoscopic appendectomy Diagnostic laparoscopy Phlegmon Appendiceal abscess
Higher-order phosphatase–substrate contacts terminate the integrated stress response
Abstract: Many regulatory PPP1R subunits join few catalytic PP1c subunits to mediate phosphoserine and phosphothreonine dephosphorylation in metazoans. Regulatory subunits engage the surface of PP1c, locally affecting flexible...
Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease.
Lisa Mayr, Felix Grabherr, Julian Schwärzler, Isabelle Reitmeier, Felix Sommer, Thomas Gehmacher, Lukas Niederreiter, Gui-Wei He, Barbara Ruder, Kai T R Kunz, Piotr Tymoszuk, Richard Hilbe, David Haschka, Clemens Feistritzer, Romana R Gerner, Barbara Enrich, Nicole Przysiecki, Markus Seifert, Markus A Keller, Georg Oberhuber, Susanne Sprung, Qitao Ran, Robert Koch, Maria Effenberger, Ivan Tancevski, Heinz Zoller, Alexander R Moschen, Günter Weiss, Christoph Becker, Philip Rosenstiel, Arthur Kaser, Herbert Tilg, Timon E Adolph
May 16, 2020
The increased incidence of inflammatory bowel disease (IBD) has become a global phenomenon that could be related to adoption of a Western life-style. Westernization of dietary habits is partly characterized by enrichment with...
Published by: Nature Communications
FICD acts bifunctionally to AMPylate and de-AMPylate the endoplasmic reticulum chaperone BiP
Vascular Smooth Muscle Cell Plasticity and Autophagy in Dissecting Aortic Aneurysms.
Marc Clément, Joel Chappell, Juliette Raffort, Fabien Lareyre, Marie Vandestienne, Annabel L Taylor, Alison Finigan, James Harrison, Martin R Bennett, Patrick Bruneval, Soraya Taleb, Helle F Jørgensen, Ziad Mallat
Mar 29, 2019
Objective- Recent studies suggested the occurrence of phenotypic switching of vascular smooth muscle cells (VSMCs) during the development of aortic aneurysm (AA). However, lineage-tracing studies are still lacking, and the...
Angiotensin II Autophagy clones Endoplasmic Reticulum Inflammation Mice Smooth muscle cells Adult Aged aortic dissection Angiotensin II Animals Aorta Aortic Aneurysm Autophagy Autophagy-Related Protein 5 Cell Lineage Cell Plasticity Cells Cultured Disease Models Animal Endoribonucleases Female Humans Male Mice 129 Strain Mice Inbred C57BL Mice Knockout ApoE Middle Aged Muscle Smooth Vascular Myocytes Smooth Muscle Phenotype Protein Serine-Threonine Kinases Signal Transduction
Generic membrane spanning features endow IRE1α with responsiveness to membrane aberrancy
Animals CHO Cells Cell Membrane Cricetulus DNA-Binding Proteins Endoplasmic Reticulum Endoplasmic reticulum stress Endoribonucleases Lipids Membrane Proteins Membranes Mutation Palmitic Acid Protein Domains Protein Folding Protein Serine-Threonine Kinases Signal Transduction Transcription Factors Unfolded Protein Response eIF-2 Kinase
Charlotte Orchestra to Play Winthrop Professor's Music
Winthrop University
Jan 01, 0001
The Charlotte Civic Orchestra will premiere "Torque," an original composition by faculty member Ron Parks, Nov. 12. The 3 p.m. concert will be held at University City Methodist Church.
Published by: Winthrop University
Upperclassmen Selected as Homecoming King and Queen
Winthrop University
Jan 01, 0001
Junior Ron Nelson and senior Sharetta Wynn were voted Homecoming King and Queen for Winthrop's Homecoming Fall 2009. They accepted their crowns Saturday, Nov. 14, during halftime of the men's basketball game against Limestone...
Published by: Winthrop University
Dietary lipids fuel GPX4-restricted enteritis resembling Crohn's disease.
Lisa Mayr, Felix Grabherr, Julian Schwärzler, Isabelle Reitmeier, Felix Sommer, Thomas Gehmacher, Lukas Niederreiter, Gui-Wei He, Barbara Ruder, Kai TR Kunz, Piotr Tymoszuk, Richard Hilbe, David Haschka, Clemens Feistritzer, Romana R Gerner, Barbara Enrich, Nicole Przysiecki, Markus Seifert, Markus A Keller, Georg Oberhuber, Susanne Sprung, Qitao Ran, Robert Koch, Maria Effenberger, Ivan Tancevski, Heinz Zoller, Alexander R Moschen, Günter Weiss, Christoph Becker, Philip Rosenstiel, Arthur Kaser, Herbert Tilg, Timon E Adolph
Apr 08, 2020
The increased incidence of inflammatory bowel disease (IBD) has become a global phenomenon that could be related to adoption of a Western life-style. Westernization of dietary habits is partly characterized by enrichment with...
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