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Results: 240
A genome wide association study of pulmonary tuberculosis susceptibility in Indonesians.
Eileen Png, Bachti Alisjahbana, Edhyana Sahiratmadja, Sangkot Marzuki, Ron Nelwan, Yanina Balabanova, Vladyslav Nikolayevskyy, Francis Drobniewski, Sergey Nejentsev, Iskandar Adnan, Esther van de Vosse, Martin L Hibberd, Reinout van Crevel, Tom HM Ottenhoff, Mark Seielstad
Feb 27, 2012
Octane Appetite
Sarah Remmert, Steven Campbell, Roger Cracknell, Andrea Schuetze, Andrew Lewis, Karl Giles, Sam Akehurst, James Turner, Andrew Popplewell, Rishin Patel
Nov 30, 2014
Market demand for high performance gasoline vehicles and increasingly strict government emissions regulations are driving the development of highly downsized, boosted direct injection engines. The in-cylinder temperatures and...
Higher-order phosphatase-substrate contacts terminate the integrated stress response.
Higher-order phosphatase–substrate contacts terminate the integrated stress response
Abstract: Many regulatory PPP1R subunits join few catalytic PP1c subunits to mediate phosphoserine and phosphothreonine dephosphorylation in metazoans. Regulatory subunits engage the surface of PP1c, locally affecting flexible...
FICD acts bifunctionally to AMPylate and de-AMPylate the endoplasmic reticulum chaperone BiP
Generic membrane spanning features endow IRE1α with responsiveness to membrane aberrancy
Animals CHO Cells Cell Membrane Cricetulus DNA-Binding Proteins Endoplasmic Reticulum Endoplasmic reticulum stress Endoribonucleases Lipids Membrane Proteins Membranes Mutation Palmitic Acid Protein Domains Protein Folding Protein Serine-Threonine Kinases Signal Transduction Transcription Factors Unfolded Protein Response eIF-2 Kinase
Upperclassmen Selected as Homecoming King and Queen
Winthrop University
Jan 01, 0001
Junior Ron Nelson and senior Sharetta Wynn were voted Homecoming King and Queen for Winthrop's Homecoming Fall 2009. They accepted their crowns Saturday, Nov. 14, during halftime of the men's basketball game against Limestone...
Published by: Winthrop University
Charlotte Orchestra to Play Winthrop Professor's Music
Winthrop University
Jan 01, 0001
The Charlotte Civic Orchestra will premiere "Torque," an original composition by faculty member Ron Parks, Nov. 12. The 3 p.m. concert will be held at University City Methodist Church.
Published by: Winthrop University
Rebalancing the Spatial Economy
Ron Martin
Jul 01, 2015
AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation.
The endoplasmic reticulum (ER)-localized Hsp70 chaperone BiP contributes to protein folding homeostasis by engaging unfolded client proteins in a process that is tightly coupled to ATP binding and hydrolysis. The inverse...
AMPylation BiP HSP70 J-proteins Biochemistry biophysics Endoplasmic Reticulum None structural biology Adenosine Monophosphate Adenosine Triphosphatases Adenosine Triphosphate Animals Cricetinae Crystallography X-Ray Endoplasmic Reticulum Chaperone BiP HEAT-SHOCK PROTEINS Hydrolysis Models Molecular Protein Binding Protein Conformation Protein Processing Post-Translational
Winthrop Faculty Members to be Featured in Providence Chamber Music Series
Winthrop University
Jan 01, 0001
The concert will feature a trio piece, "Things Get Out of Hand," composed by associate professor Ron Parks. The concert is 7 p.m. Oct 7 at Providence United Methodist Church in Charlotte. It is free and open to the public.
Published by: Winthrop University
Charlotte Symphony Orchestra to Perform Nov. 15 at Winthrop
Winthrop University
Jan 01, 0001
Guest conductor Chelsea Tipton will lead the 4 p.m. Nov. 15 concert in Byrnes Auditorium. Winthrop composer Ron Parks will perform one of his original pieces in a pre-concert at 3 p.m.
Published by: Winthrop University
How Do CIOs Become CEOs?
The role of information systems and technologies in any modern organization has become increasingly important. Concepts such as digital transformation and disruptive technologies have become the strategic directions for new and...
Published by: IGI Global Scientific Publishing
Pharmacological targeting of endoplasmic reticulum stress in disease.
The accumulation of misfolded proteins in the endoplasmic reticulum (ER) leads to ER stress, resulting in activation of the unfolded protein response (UPR) that aims to restore protein homeostasis. However, the UPR also plays an...
Option Values in Sequential Auctions with Time-Varying Valuations
We investigate second-price sequential auctions of unit-demand bidders with time-variable valuations under complete information. We describe how a bidder figures willingness to pay by calculating option values, and show that...
Winthrop Faculty Members Honored For Service and Dedication
Winthrop University
Jan 01, 0001
Melford Wiilson, professor of political science and director of the International Center, will be awarded the Distinguished Professor Award. The Outstanding Junior Professor Award will go to Ron Parks, an assisstant professor of...
Published by: Winthrop University
Modulation of Innate Immune Signalling by Lipid-Mediated MAVS Transmembrane Domain Oligomerization.
Faculty Members Showcase Their New Works at Winthrop Galleries
Winthrop University
Jan 01, 0001
As part of the "New Works" exhibition, fine arts faculty members Paul Martyka and Marge Loudon Moody will exhibit new pieces in the Rutledge Gallery. Phil Moody of fine arts has collaborated with design faculty Gerry Derksen...
Published by: Winthrop University
Asymptotic behaviour of a pile-up of infinite walls of edge dislocations
We consider a system of parallel straight edge dislocations and we analyse its asymptotic behaviour in the limit of many dislocations. The dislocations are represented by points in a plane, and they are arranged in vertical...
Worst-case Bounds on Power vs. Proportion in Weighted Voting Games with Application to False-Name Manipulation
Weighted voting games apply to a wide variety of multi-agent settings. They enable the formalization of power indices which quantify the coalitional power of players. We take a novel approach to the study of the power of big...
Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes
The metazoan endoplasmic reticulum (ER) serves both as a hub for maturation of secreted proteins and as an intracellular calcium storage compartment, facilitating calcium-release-dependent cellular processes. ER calcium...
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