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Results: 39
Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease
Siddhartha Jaiswal, Pradeep Natarajan, Alexander J Silver, Christopher J Gibson, Alexander G Bick, Eugenia Shvartz, Marie McConkey, Namrata Gupta, Stacey Gabriel, Diego Ardissino, Usman Baber, Roxana Mehran, Valentin Fuster, John Danesh, Philippe Frossard, Danish Saleheen, Olle Melander, Galina K Sukhova, Donna Neuberg, Peter Libby, Sekar Kathiresan, Benjamin L Ebert
Nov 28, 2017
Does Age Matter?
Previous literature has suggested that age indirectly influences the intention to adopt an information technology, and notably a m-health application. However, few studies have investigated this link. Voluntarily proximity...
Published by: IGI Global Scientific Publishing
Changing trends in the management of intertrochanteric hip fractures - a single centre experience
Piers R. J. Page, Roxana Lord, Ahsin Jawad, Edward Dawe, Philip Stott, Benedict Rogers, Richie Gill
Jul 01, 2016
With an annual incidence greater than 65,000 in the United
Kingdom, hip fractures are a common but debilitating injury predominantly
affecting those over 65. Treatment is based on the anatomical location of
the...
Kingdom, hip fractures are a common but debilitating injury predominantly
affecting those over 65. Treatment is based on the anatomical location of
the...
Novel surface features for automated detection of focal cortical dysplasias in paediatric epilepsy.
Sophie Adler, Konrad Wagstyl, Roxana Gunny, Lisa Ronan, David Carmichael, J Helen Cross, Paul C Fletcher, Torsten Baldeweg
Jun 18, 2018
AUC area under the curve Automated classification FCD FCD focal cortical dysplasia FLAIR fluid-attenuated inversion recovery Intractable epilepsy LCD local cortical deformation LGI local gyrification index PCA principal component analysis paediatric ROC receiver operator characteristic Structural MRI Adolescent Area Under Curve Brain Mapping Cerebral Cortex Child Child Preschool Epilepsy Female Humans Imaging Three-Dimensional Machine Learning Magnetic Resonance Imaging Male Malformations of Cortical Development Group I Oxygen
Structure of Neutron Stars in Massive Scalar-Tensor Gravity
Roxana Rosca-Mead, Christopher J. Moore, Ulrich Sperhake, Michalis Agathos, Davide Gerosa
Aug 20, 2020
We compute families of spherically symmetric neutron-star models in two-derivative scalar-tensor theories of gravity with a massive scalar field. The numerical approach we present allows us to compute the resulting spacetimes...
Changing trends in the management of intertrochanteric hip fractures - a single centre experience
Piers R. J. Page, Roxana Lord, Ahsin Jawad, Edward Dawe, Philip Stott, Benedict Rogers, Richie Gill
Jul 01, 2016
With an annual incidence greater than 65,000 in the United
Kingdom, hip fractures are a common but debilitating injury predominantly
affecting those over 65. Treatment is based on the anatomical location of
the...
Kingdom, hip fractures are a common but debilitating injury predominantly
affecting those over 65. Treatment is based on the anatomical location of
the...
Proteomics identifies neddylation as a potential therapy target in small intestinal neuroendocrine tumors.
Omid Fotouhi, Hanna Kjellin, C Christofer Juhlin, Yanbo Pan, Mattias Vesterlund, Mehran Ghaderi, Abdelhamid Yousef, Hillevi Andersson-Sand, Pedram Kharaziha, Stefano Caramuta, Magnus Kjellman, Jan Zedenius, Catharina Larsson, Lukas M Orre
Aug 11, 2020
Patients with small intestinal neuroendocrine tumors (SI-NETs) frequently develop spread disease; however, the underlying molecular mechanisms of disease progression are not known and effective preventive treatment strategies...
Long-Lived Inverse Chirp Signals from Core-Collapse in Massive Scalar-Tensor Gravity.
Ulrich Sperhake, Christopher J Moore, Roxana Rosca, Michalis Agathos, Davide Gerosa, Christian D Ott
Jun 13, 2018
This Letter considers stellar core collapse in massive scalar-tensor theories of gravity. The presence of a mass term for the scalar field allows for dramatic increases in the radiated gravitational wave signal. There are...
Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting
P Natarajan, R Young, NO Stitziel, S Padmanabhan, U Baber, R Mehran, S Sartori, V Fuster, DF Reilly, A Butterworth, DJ Rader, I Ford, N Sattar, S Kathiresan
Oct 30, 2017
Background: Relative risk reduction with statin therapy has been consistent across nearly all subgroups studied to date. However, in analyses of 2 randomized controlled primary prevention trials (ASCOT [Anglo-Scandinavian...
Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors Polymorphism Genetic Primary Prevention Vascular Calcification Adolescent Adult Aged Aged 80 and over Atherosclerosis Cohort Studies Cost of Illness Female Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors Male Middle Aged Multifactorial Inheritance Primary Prevention Risk Factors Young Adult
Neuroergonomic Assessment of Wheelchair Control Using Mobile fNIRS
Shawn Joshi, Roxana Ramirez Herrera, Daniella Nicole Springett, Benjamin David Weedon, Dafne Zuleima Morgado Ramirez, Catherine Holloway, Helen Dawes, Hasan Ayaz
May 04, 2020
For over two centuries, the wheelchair has been one of the most common assistive devices for individuals with locomotor impairments without many modifications. Wheelchair control is a complex motor task that increases both...
The negative regulator SMAX1 controls mycorrhizal symbiosis and strigolactone biosynthesis in rice
Jeongmin Choi, Tak Lee, Jungnam Cho, Emily K. Servante, Boas Pucker, William Summers, Sarah Bowden, Mehran Rahimi, Kyungsook An, Gynheung An, Harro J. Bouwmeester, Emma J. Wallington, Giles Oldroyd, Uta. Paszkowski
Apr 30, 2021
Abstract: Most plants associate with beneficial arbuscular mycorrhizal (AM) fungi that facilitate soil nutrient acquisition. Prior to contact, partner recognition triggers reciprocal genetic remodelling to enable colonisation....
The negative regulator SMAX1 controls mycorrhizal symbiosis and strigolactone biosynthesis in rice.
Jeongmin Choi, Tak Lee, Jungnam Cho, Emily K Servante, Boas Pucker, William Summers, Sarah Bowden, Mehran Rahimi, Kyungsook An, Gynheung An, Harro J Bouwmeester, Emma J Wallington, Giles Oldroyd, Uta Paszkowski
Apr 15, 2020
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.
Raphaël Rodriguez, Kyle M Miller, Josep V Forment, Charles R Bradshaw, Mehran Nikan, Sébastien Britton, Tobias Oelschlaegel, Blerta Xhemalce, Shankar Balasubramanian, Stephen P Jackson
Jan 24, 2018
Guanine-rich DNA sequences that can adopt non-Watson-Crick structures in vitro are prevalent in the human genome. Whether such structures normally exist in mammalian cells has, however, been the subject of active research for...
Enhancing Distraction Osteogenesis With Carbon Fiber Reinforced Polyether Ether Ketone Bone Pins and a Three-Dimensional Printed Transfer Device to Permit Artifact-Free Three-Dimensional Magnetic Resonance Imaging.
Karen A Eley, Mehran Moazen, Gaspar Delso, Maryam Javidan, Joshua Kaggie, Deepak M Kalaskar, Jonathan C Knowles, Nazanin Owji, Stephen R Watt-Smith
Jun 29, 2020
Neuroergonomic Assessment of Wheelchair Control Using Mobile fNIRS
Shawn Joshi, Roxana Ramirez Herrera, Daniella Nicole Springett, Benjamin David Weedon, Dafne Zuleima Morgado Ramirez, Catherine Holloway, Helen Dawes, Hasan Ayaz
May 04, 2020
For over two centuries, the wheelchair has been one of the most common assistive devices for individuals with locomotor impairments without many modifications. Wheelchair control is a complex motor task that increases both...
Engineering chloroplast development in rice through cell-specific control of endogenous genetic circuits.
Dong-Yeon Lee, Lei Hua, Roxana Khoshravesh, Rita Giuliani, Indrajit Kumar, Asaph Cousins, Tammy L Sage, Julian M Hibberd, Thomas P Brutnell
Jul 22, 2021
Engineering chloroplast development in rice through cell‐specific control of endogenous genetic circuits
Dong‐Yeon Lee, Lei Hua, Roxana Khoshravesh, Rita Giuliani, Indrajit Kumar, Asaph Cousins, Tammy L. Sage, Julian M. Hibberd, Thomas P. Brutnell
Aug 18, 2021
Summary: The engineering of C4 photosynthetic activity into the C3 plant rice has the potential to nearly double rice yields. To engineer a two‐cell photosynthetic system in rice, the rice bundle sheath (BS) must be rewired to...
Original Article Original Articles C4 photosynthesis dCas9‐mediated transcriptional activation rice bundle sheath chloroplast development
Published by: Plant Biotechnology Journal
Targeted transcriptomics reveals signatures of large-scale independent origins and concerted regulation of effector genes in Radopholus similis.
Paulo Vieira, Roxana Y Myers, Clement Pellegrin, Catherine Wram, Cedar Hesse, Thomas R Maier, Jonathan Shao, Georgios D Koutsovoulos, Inga Zasada, Tracie Matsumoto, Etienne GJ Danchin, Thomas J Baum, Sebastian Eves-van den Akker, Lev G Nemchinov
Nov 22, 2021
The burrowing nematode, Radopholus similis, is an economically important plant-parasitic nematode that inflicts damage and yield loss to a wide range of crops. This migratory endoparasite is widely distributed in warmer regions...
An Action Design Research to Facilitate the Adoption of Personal Health Records
Rhode Ngassam, Linnea Ung, Roxana Ologeanu-Taddei, Jorick Lartigau, Pascal Demoly, Isabelle Bourdon, nicolas Molinari, Anca Chiriac
Jul 01, 2022
Adoption and user perceptions are dominant on personal health records literature and have led to a better understanding of what individuals' behaviors and perceptions are about the adoption of personal health records. However...
Published by: IGI Global Scientific Publishing
Targeting Cell Death Mechanism Specifically in Triple Negative Breast Cancer Cell Lines.
Lavinia-Lorena Pruteanu, Cornelia Braicu, Dezső Módos, Maria-Ancuţa Jurj, Lajos-Zsolt Raduly, Oana Zănoagă, Lorand Magdo, Roxana Cojocneanu, Sergiu Paşca, Cristian Moldovan, Alin Iulian Moldovan, Adrian Bogdan Ţigu, Eugen Gurzău, Lorentz Jäntschi, Andreas Bender, Ioana Berindan-Neagoe
Jun 14, 2022
Triple negative breast cancer (TNBC) is currently associated with a lack of treatment options. Arsenic derivatives have shown antitumoral activity both in vitro and in vivo; however, their mode of action is not completely...
Targeted transcriptomics reveals signatures of large-scale independent origins and concerted regulation of effector genes in Radopholus similis.
Paulo Vieira, Roxana Y Myers, Clement Pellegrin, Catherine Wram, Cedar Hesse, Thomas R Maier, Jonathan Shao, Georgios D Koutsovoulos, Inga Zasada, Tracie Matsumoto, Etienne GJ Danchin, Thomas J Baum, Sebastian Eves-van den Akker, Lev G Nemchinov
Jan 07, 2022
The burrowing nematode, Radopholus similis, is an economically important plant-parasitic nematode that inflicts damage and yield loss to a wide range of crops. This migratory endoparasite is widely distributed in warmer regions...
Tracing oncogene-driven remodelling of the intestinal stem cell niche.
Min Kyu Yum, Seungmin Han, Juergen Fink, Szu-Hsien Sam Wu, Catherine Dabrowska, Teodora Trendafilova, Roxana Mustata, Lemonia Chatzeli, Roberta Azzarelli, Irina Pshenichnaya, Eunmin Lee, Frances England, Jong Kyoung Kim, Daniel E Stange, Anna Philpott, Joo-Hyeon Lee, Bon-Kyoung Koo, Benjamin D Simons
Apr 07, 2021
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