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Results: 63
Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction.
Tu'uhevaha J Kaitu'u-Lino, Teresa M MacDonald, Ping Cannon, Tuong-Vi Nguyen, Richard J Hiscock, Nick Haan, Jenny E Myers, Roxanne Hastie, Kirsten M Dane, Anna L Middleton, Intissar Bittar, Amanda N Sferruzzi-Perri, Natasha Pritchard, Alesia Harper, Natalie J Hannan, Valerie Kyritsis, Nick Crinis, Lisa Hui, Susan P Walker, Stephen Tong
Jul 17, 2020
Placental insufficiency can cause fetal growth restriction and stillbirth. There are no reliable screening tests for placental insufficiency, especially near-term gestation when the risk of stillbirth rises. Here we show a...
Animals Anthropometry Biomarkers Female Fetal Growth Retardation Humans Infant Newborn Infant Small for Gestational Age Mice Placenta Placental Insufficiency Plethysmography Predictive Value of Tests Pregnancy Pregnancy Trimester Third Proteinase Inhibitory Proteins Secretory Sensitivity and Specificity Ultrasonography Prenatal Umbilical Arteries Uterine Artery
Impulsivity in Gambling Disorder and problem gambling
Gambling Disorder is a prevalent psychiatric condition often linked to dysfunction of cognitive domains regulating impulsive behavior. Despite the centrality of impulsivity to neurobiological models of Gambling Disorder, a...
It Takes a Community to Educate a Child
This study was part of a larger research project examining education success across the Inuit regions of Canada. This case study highlights the insights of students, educators, and parents in considering the factors contributing...
Published by: The Morning Watch: Educational and Social Analysis
It Takes a Community to Educate a Child
This study was part of a larger research project examining education success across the Inuit regions of Canada. This case study highlights the insights of students, educators, and parents in considering the factors contributing...
Published by: The Morning Watch: Educational and Social Analysis
An ant colony algorithm for the multi-compartment vehicle routing problem
We demonstrate the use of Ant Colony System (ACS) to solve the capacitated
vehicle routing problem associated with collection of recycling waste from
households, treated as nodes in a spatial network. For networks where...
vehicle routing problem associated with collection of recycling waste from
households, treated as nodes in a spatial network. For networks where...
Which Democratic Way to Go?
There are concerns amongst researchers and the general public that social media platforms threaten democratic values. Social media corporations and their engineers have responded to these concerns with various design solutions....
Published by: IGI Global Scientific Publishing
Using the internet to cope with chronic fatigue syndrome/myalgic encephalomyelitis in adolescence
Background: Adolescents are increasingly using online resources for health purposes. Previous studies suggest that online provision of information about chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) is...
An ant colony algorithm for the multi-compartment vehicle routing problem
We demonstrate the use of Ant Colony System (ACS) to solve the capacitated
vehicle routing problem associated with collection of recycling waste from
households, treated as nodes in a spatial network. For networks where...
vehicle routing problem associated with collection of recycling waste from
households, treated as nodes in a spatial network. For networks where...
Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction
Tu’uhevaha J. Kaitu’u-Lino, Teresa M. MacDonald, Ping Cannon, Tuong-Vi Nguyen, Richard J. Hiscock, Nick Haan, Jenny E. Myers, Roxanne Hastie, Kirsten M. Dane, Anna L. Middleton, Intissar Bittar, Amanda N. Sferruzzi-Perri, Natasha Pritchard, Alesia Harper, Natalie J. Hannan, Valerie Kyritsis, Nick Crinis, Lisa Hui, Susan P. Walker, Stephen Tong
May 20, 2021
Neuronal Reprogramming for Tissue Repair and Neuroregeneration
Stem cell and cell reprogramming technology represent a rapidly growing field in regenerative medicine. A number of novel neural reprogramming methods have been established, using pluripotent stem cells (PSCs) or direct...
Trans-diagnostic measurement of impulsivity and compulsivity
Roxanne W Hook, Jon E Grant, Konstantinos Ioannidis, Jeggan Tiego, Murat Yücel, Paul Wilkinson, Samuel R Chamberlain
Oct 26, 2020
INTRODUCTION: Impulsivity and compulsivity are important constructs, relevant to understanding behaviour in the general population, as well as in particular mental disorders (e.g. attention deficit hyperactivity disorder...
Using the internet to cope with chronic fatigue syndrome/myalgic encephalomyelitis in adolescence
Background: Adolescents are increasingly using online resources for health purposes. Previous studies suggest that online provision of information about chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) is...
Cognitive deficits in problematic internet use
Konstantinos Ioannidis, Roxanne Hook, Anna E Goudriaan, Simon Vlies, Naomi A Fineberg, Jon E Grant, Samuel R Chamberlain
Feb 05, 2019
BACKGROUND: Excessive use of the internet is increasingly recognised as a global public health concern. Individual studies have reported cognitive impairment in problematic internet use (PIU), but have suffered from various...
A Diffusion-like Process Accommodates New Crypts During Clonal Expansion in Human Colonic Epithelium.
Cora Olpe, Doran Khamis, Maria Chukanova, Nefeli Skoufou-Papoutsaki, Richard Kemp, Kate Marks, Cerys Tatton, Cecilia Lindskog, Anna Nicholson, Roxanne Brunton-Sim, Shalini Malhotra, Rogier Ten Hoopen, Rachael Stanley, Douglas J Winton, Edward Morrissey
Apr 16, 2021
BACKGROUND & AIMS: Colorectal cancer (CRC) is thought to arise when the cumulative mutational burden within colonic crypts exceeds a certain threshold that leads to clonal expansion and ultimately neoplastic transformation....
Colorectal Cancer Initiation crypt fission crypt fusion Intestinal Crypt Adolescent Adult Age Factors Aged Aged 80 and over Cell Proliferation Cell Transformation Neoplastic Colonic Polyps Colorectal Neoplasms Diffusion Epithelial Cells Female Histone Demethylases Humans Intestinal Mucosa Male Middle Aged Models Biological Mutation Neoplastic Stem Cells Proto-Oncogene Proteins p21(ras) Young Adult
Antenatal Exposure to UV-B Radiation and Preeclampsia
Claire E Hastie, Daniel F Mackay, Tom L Clemens, Mark PC Cherrie, Lauren J Megaw, Gordon CS Smith, Sarah J Stock, Chris Dibben, Jill P Pell
May 24, 2021
Neuronal Reprogramming for Tissue Repair and Neuroregeneration.
Stem cell and cell reprogramming technology represent a rapidly growing field in regenerative medicine. A number of novel neural reprogramming methods have been established, using pluripotent stem cells (PSCs) or direct...
Improving outcomes in adults with epilepsy and intellectual disability (EpAID) using a nurse-led intervention
Howard Ring, Nakita Gilbert, Roxanne Hook, Adam Platt, Christopher Smith, Fiona Irvine, Cam Donaldson, Elizabeth Jones, Joanna Kelly, Adrian Mander, Caroline Murphy, Mark Pennington, Angela Pullen, Marcus Redley, Simon Rowe, James Wason
Jun 09, 2016
clinical trial Clinical trials unit Cluster trial Controlled trial cost-effectiveness Epilepsy Epilepsy nurse Intellectual Disability Nurse-led intervention Pragmatic Quality of life Randomised Treatment Treatment as usual Adult Clinical Protocols Data Collection Epilepsy Humans Intellectual Disability Nurses Outcome Assessment Health Care qualitative research Research Design Sample Size
Pay for performance at a crossroads
Soren Kristensen, Laura Anselmi, Garrett Wallace Brown, Eleonora Fichera, Gwati Gwati, Roxanne Kovacs, Rene Loewenson, Nicholas Midzi, Fatimah Mustapha, Neha Singh, Lee White, Josephine Borghi
Aug 31, 2023
Purpose: The use of pay for performance (P4P) as an instrument to incentivise quality improvements in health care is at a crossroads in high-income countries but has remained a commonly used tool in low- and middle-income...
pay for performance Quality Improvement Quality of Health Care /dk/atira/pure/subjectarea/asjc/3300/3305 name=Geography, Planning and Development /dk/atira/pure/subjectarea/asjc/3300/3320 name=Political Science and International Relations /dk/atira/pure/subjectarea/asjc/2300/2308 name=Management, Monitoring, Policy and Law /dk/atira/pure/subjectarea/asjc/3300/3321 name=Public Administration
The impact of the initial COVID-19 outbreak on young adults' mental health
Anna Wiedemann, Jan Stochl, Sharon AS Neufeld, Jessica Fritz, Junaid Bhatti, Roxanne W Hook, NSPN Consortium, Ian M Goodyer, Raymond J Dolan, Edward T Bullmore, Samuel R Chamberlain, Peter Fonagy, Jesus Perez, Peter B Jones
Nov 05, 2022
Defining Disease Phenotypes in Primary Care Electronic Health Records by a Machine Learning Approach
Shang-Ming Zhou, Fabiola Fernandez-Gutierrez, Jonathan Kennedy, Roxanne Cooksey, Mark Atkinson, Spiros Denaxas, Stefan Siebert, William G Dixon, Terence W O'Neill, Ernest Choy, Cathie Sudlow, UK Biobank Follow-up and Outcomes Group, Sinead Brophy
Nov 20, 2017
OBJECTIVES: 1) To use data-driven method to examine clinical codes (risk factors) of a medical condition in primary care electronic health records (EHRs) that can accurately predict a diagnosis of the condition in secondary care...
The impact of the initial COVID-19 outbreak on young adults' mental health
Pay for performance at a crossroads
Soren Kristensen, Laura Anselmi, Garrett Wallace Brown, Eleonora Fichera, Gwati Gwati, Roxanne Kovacs, Rene Loewenson, Nicholas Midzi, Fatimah Mustapha, Neha Singh, Lee White, Josephine Borghi
Aug 31, 2023
Purpose: The use of pay for performance (P4P) as an instrument to incentivise quality improvements in health care is at a crossroads in high-income countries but has remained a commonly used tool in low- and middle-income...
pay for performance Quality Improvement Quality of Health Care /dk/atira/pure/subjectarea/asjc/3300/3305 name=Geography, Planning and Development /dk/atira/pure/subjectarea/asjc/3300/3320 name=Political Science and International Relations /dk/atira/pure/subjectarea/asjc/2300/2308 name=Management, Monitoring, Policy and Law /dk/atira/pure/subjectarea/asjc/3300/3321 name=Public Administration
Brain micro-architecture and disinhibition
Rafa Romero-Garcia, Roxanne W. Hook, Jeggan Tiego, Richard A. I. Bethlehem, Ian M. Goodyer, Peter B. Jones, Ray Dolan, Jon E. Grant, Edward T. Bullmore, Murat Yücel, Samuel R. Chamberlain
Dec 07, 2020
Abstract: Impulsive and compulsive symptoms are common, tend to co-occur, and collectively account for a substantive global disease burden. Latent phenotyping offers a promising approach to elucidate common neural mechanisms...
Fractionation of impulsive and compulsive trans-diagnostic phenotypes and their longitudinal associations.
Samuel R Chamberlain, Jeggan Tiego, Leonardo F Fontenelle, Roxanne Hook, Linden Parkes, Rebecca Segrave, Tobias U Hauser, Ray J Dolan, Ian M Goodyer, Ed Bullmore, Jon E Grant, Murat Yücel
Apr 05, 2019
OBJECTIVE: Young adulthood is a crucial neurodevelopmental period during which impulsive and compulsive problem behaviours commonly emerge. While traditionally considered diametrically opposed, impulsive and compulsive symptoms...
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