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PA6 Stromal Cell Co-Culture Enhances SH-SY5Y and VSC4.1 Neuroblastoma Differentiation to Mature Phenotypes
Neuroblastoma cell lines such as SH-SY5Y have been used for modelling neurodegenerative diseases and for studying basic mechanisms in neuroscience. Since neuroblastoma cells proliferate and generally do not express markers of...
Insights into the clinical management of the syndrome of supine hypertension--orthostatic hypotension (SH-OH)
Roman Romero-Ortuno, Matthew DL O'Connell, Ciaran Finucane, Christopher Soraghan, Chie Wei Fan, Rose Anne Kenny
Jan 25, 2018
BACKGROUND: Our previously proposed morphological classification of orthostatic hypotension (MOH) is an approach to the definition of three typical orthostatic hemodynamic patterns using non-invasive beat-to-beat monitoring. In...
PA6 Stromal Cell Co-Culture Enhances SH-SY5Y and VSC4.1 Neuroblastoma Differentiation to Mature Phenotypes
Neuroblastoma cell lines such as SH-SY5Y have been used for modelling neurodegenerative diseases and for studying basic mechanisms in neuroscience. Since neuroblastoma cells proliferate and generally do not express markers of...
Altered Processing of β-Amyloid in SH-SY5Y Cells Induced by Model Senescent Microglia
The single greatest risk factor for neurodegenerative diseases is aging. Aging of cells such as microglia in the nervous system has an impact not only on the ability of those cells to function but also on cells they interact...
APP ER stress Autophagy insulin degrading enzyme Microglia β-amyloid /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1314 name=Physiology /dk/atira/pure/subjectarea/asjc/2800/2805 name=Cognitive Neuroscience /dk/atira/pure/subjectarea/asjc/1300/1307 name=Cell Biology /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells.
Jason C Sang, Eric Hidari, Georg Meisl, Rohan T Ranasinghe, Maria Grazia Spillantini, David Klenerman
Jun 22, 2021
Aggregation of α-synuclein (α-syn) is closely linked to Parkinson's disease (PD) and the related synucleinopathies. Aggregates spread through the brain during the progression of PD, but the mechanism by which this occurs is...
Published by: Communications biology
Direct evidence of polar ferroelastic domain boundaries in semiconductor BiVO4
Ferroelastic domain boundaries in semiconductor bismuth vanadate, BiVO4, are examined using second harmonic generation microscopy.
Although the bulk is centrosymmetric, domain boundaries produce homogeneous second harmonic (SH)...
Altered Processing of β-Amyloid in SH-SY5Y Cells Induced by Model Senescent Microglia
The single greatest risk factor for neurodegenerative diseases is aging. Aging of cells such as microglia in the nervous system has an impact not only on the ability of those cells to function but also on cells they interact...
APP ER stress Autophagy insulin degrading enzyme Microglia β-amyloid /dk/atira/pure/subjectarea/asjc/1300/1303 name=Biochemistry /dk/atira/pure/subjectarea/asjc/1300/1314 name=Physiology /dk/atira/pure/subjectarea/asjc/2800/2805 name=Cognitive Neuroscience /dk/atira/pure/subjectarea/asjc/1300/1307 name=Cell Biology /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Enhancement of polar nature of domain boundaries in ferroelastic Pb3(PO4)2 by doping divalent-metal ions.
The effect of doping metal ions in ferroelastic Pb3(PO4)2 (PPO) on the polar nature of domain boundaries (DBs) was investigated using a second harmonic generation (SHG) microscope. It has been already reported that (DBs) of...
Low DHEAS
M Conall Dennedy, Anand K Annamalai, Olivia Prankerd-Smith, Natalie Freeman, Kuhan Vengopal, Johann Graggaber, Olympia Koulouri, Andrew S Powlson, Ashley Shaw, David J Halsall, Mark Gurnell
Jun 27, 2018
CONTEXT: Subclinical hypercortisolism (SH) occurs in 5% to 30% of adrenal incidentalomas (AIs). Common screening tests for adrenocorticotropin-independent hypercortisolism have substantial false-positive rates, mandating further...
Humans Pheochromocytoma Adenoma Adrenocortical Carcinoma Adrenal Gland Neoplasms Adrenal Cortex Neoplasms Cushing Syndrome hyperaldosteronism Dehydroepiandrosterone Sulfate Dexamethasone aldosterone Hydrocortisone Renin Glucocorticoids Sensitivity and Specificity Retrospective Studies ROC Curve Adolescent Adult Middle Aged Female Male Adrenocorticotropic Hormone Young Adult
Thiol-Anchored TIPS-Tetracene Ligands with Quantitative Triplet Energy Transfer to PbS Quantum Dots and Improved Thermal Stability.
Victor Gray, Zhilong Zhang, Simon Dowland, Jesse R Allardice, Antonios M Alvertis, James Xiao, Neil C Greenham, John E Anthony, Akshay Rao
Aug 14, 2020
Triplet energy transfer between inorganic quantum dots (QDs) and organic materials plays a fundamental role in many optoelectronic applications based on these nanocomposites. Attaching organic molecules to the QD as transmitter...
Improved estimates of preindustrial biomass burning reduce the magnitude of aerosol climate forcing in the Southern Hemisphere.
Pengfei Liu, Jed O Kaplan, Loretta J Mickley, Yang Li, Nathan J Chellman, Monica M Arienzo, John K Kodros, Jeffrey R Pierce, Michael Sigl, Johannes Freitag, Robert Mulvaney, Mark AJ Curran, Joseph R McConnell
Jun 29, 2021
Fire plays a pivotal role in shaping terrestrial ecosystems and the chemical composition of the atmosphere and thus influences Earth's climate. The trend and magnitude of fire activity over the past few centuries are...
Neurotoxicity Induced by Okadaic Acid in the Human Neuroblastoma SH-SY5Y Line Can Be Differentially Prevented by alpha 7 and beta 2*Nicotinic Stimulation
L del Barrio, M D Martin-de-Saavedra, A Romero, E Parada, J Egea, J Avila, J M McIntosh, Susan Wonnacott, M G Lopez
Sep 01, 2011
A good model of neuronal death that reproduces the characteristic tau (tau) hyperphosphorylation of Alzheimers disease is the use of okadaic acid (OA). The aim of this study was to determine the contribution of alpha 7 and beta...
Neurotoxicity Induced by Okadaic Acid in the Human Neuroblastoma SH-SY5Y Line Can Be Differentially Prevented by alpha 7 and beta 2*Nicotinic Stimulation
L del Barrio, M D Martin-de-Saavedra, A Romero, E Parada, J Egea, J Avila, J M McIntosh, Susan Wonnacott, M G Lopez
Sep 01, 2011
A good model of neuronal death that reproduces the characteristic tau (tau) hyperphosphorylation of Alzheimers disease is the use of okadaic acid (OA). The aim of this study was to determine the contribution of alpha 7 and beta...
Coordinated Observations of 8- and 6-hr Tides in the Mesosphere and Lower Thermosphere by Three Meteor Radars Near 60<sup>°</sup>S Latitude
Guiping Liu, Diego Janches, Ruth S. Lieberman, Tracy Moffat-Griffin, David C. Fritts, Nicholas J. Mitchell
Jan 16, 2020
Atmospheric 8- and 6-hr tides are observed for the first time in the zonal and meridional winds at ~82–97 km altitudes simultaneously at Tierra del Fuego (TDF; 53.7°S, 67.7°W), King Edward Point (KEP; 54.3°S, 36.5°W), and...
Coordinated Observations of 8- and 6-hr Tides in the Mesosphere and Lower Thermosphere by Three Meteor Radars Near 60<sup>°</sup>S Latitude
Guiping Liu, Diego Janches, Ruth S. Lieberman, Tracy Moffat-Griffin, David C. Fritts, Nicholas J. Mitchell
Jan 16, 2020
Atmospheric 8- and 6-hr tides are observed for the first time in the zonal and meridional winds at ~82–97 km altitudes simultaneously at Tierra del Fuego (TDF; 53.7°S, 67.7°W), King Edward Point (KEP; 54.3°S, 36.5°W), and...
The Coupled Magmatic and Hydrothermal Systems of the Restless Aluto Caldera, Ethiopia
Seismicity can be used to better understand interactions between magma bodies, hydrothermal systems and their host rocks—key factors influencing volcanic unrest. Here, we use earthquake data to image, for the first time, the...
Global biogeographic patterns in bipolar moss species.
A bipolar disjunction is an extreme, yet common, biogeographic pattern in non-vascular plants, yet its underlying mechanisms (vicariance or long-distance dispersal), origin and timing remain poorly understood. Here, combining a...
Henri Breuil and the Imagination of Prehistory
SH Dubow
Feb 01, 2019
Other than in passing references, the Abbé Henri Breuil, French prehistorian and internationally renowned expert on rock art, is today rarely mentioned in academic accounts of South African archaeology. Breuil was nevertheless a...
Returning Thermal Advantage Instrument's DSC 2920 and SDT 2960 to Functioning Order
Ethan B Haldeman
Jan 01, 0001
Thermal Advantage (TA) Instruments DSC 2920 and SDT 2960 require a computer running Windows NT 2000 and an Industry Standard Architecture (ISA) expansion card to output and record data. Due to the lack of availability for this...
SDT 2960 DSC 2920 Windows NT 2000 Software TA Instruments Computer Sciences Physical Sciences and Mathematics Physics
Published by: Ursinus College
Note on fundamental physics tests from black hole imaging
Several works over the past years have discussed the possibility of testing
fundamental physics using Very Long Baseline Interferometry horizon-scale black
hole (BH) images, such as the Event Horizon Telescope (EHT) images of...
Antigenic Maps of Influenza A(H3N2) Produced With Human Antisera Obtained After Primary Infection.
Judith M Fonville, Pieter LA Fraaij, Gerrie de Mutsert, Samuel H Wilks, Ruud van Beek, Ron AM Fouchier, Guus F Rimmelzwaan
Jul 02, 2015
200 Years of Astronomy in South Africa
SH Dubow
Jul 29, 2019
South Africa is currently in the process of building the world’s largest radio telescope as part of an international consortium headquartered at Jodrell Bank outside Manchester, England. MeerKAT, the precursor to this ambitious...
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