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Results: 4
Diffusion-Limited Growth of Microbial Colonies.
Hayden Tronnolone, Alexander Tam, Zoltán Szenczi, JEF Green, Sanjeeva Balasuriya, Ee Lin Tek, Jennifer M Gardner, Joanna F Sundstrom, Vladimir Jiranek, Stephen G Oliver, Benjamin J Binder
Sep 20, 2018
The emergence of diffusion-limited growth (DLG) within a microbial colony on a solid substrate is studied using a combination of mathematical modelling and experiments. Using an agent-based model of the interaction between...
Sigma1 receptors inhibit store-operated Ca2+ entry by attenuating coupling of STIM1 to Orai1.
Shyam Srivats, Dilshan Balasuriya, Mathias Pasche, Gerard Vistal, J Michael Edwardson, Colin W Taylor, Ruth D Murrell-Lagnado
Feb 29, 2016
Crystal structure and molecular imaging of the Nav channel β3 subunit indicates a trimeric assembly.
Sivakumar Namadurai, Dilshan Balasuriya, Rajit Rajappa, Martin Wiemhöfer, Katherine Stott, Jurgen Klingauf, J Michael Edwardson, Dimitri Y Chirgadze, Antony P Jackson
Sep 20, 2018
The vertebrate sodium (Nav) channel is composed of an ion-conducting α subunit and associated β subunits. Here, we report the crystal structure of the human β3 subunit immunoglobulin (Ig) domain, a functionally important...
Analytical Ultracentrifugation Atomic force microscopy in vivo imaging Photoactivated Localization Microscopy Protein Trimerization Sodium Channels X-ray crystallography Amino Acid Sequence Binding Sites Cloning Molecular Crystallization Crystallography X-Ray Dimerization HEK293 Cells Humans Immunoglobulins Microscopy Atomic Force Molecular Sequence Data NAV1.5 Voltage-Gated Sodium Channel Protein Conformation Ultracentrifugation Voltage-Gated Sodium Channel beta-3 Subunit
CATMoS
Kamel Mansouri, Agnes L Karmaus, Jeremy Fitzpatrick, Grace Patlewicz, Prachi Pradeep, Domenico Alberga, Nathalie Alepee, Timothy EH Allen, Dave Allen, Vinicius M Alves, Carolina H Andrade, Tyler R Auernhammer, Davide Ballabio, Shannon Bell, Emilio Benfenati, Sudin Bhattacharya, Joyce V Bastos, Stephen Boyd, JB Brown, Stephen J Capuzzi, Yaroslav Chushak, Heather Ciallella, Alex M Clark, Viviana Consonni, Pankaj R Daga, Sean Ekins, Sherif Farag, Maxim Fedorov, Denis Fourches, Domenico Gadaleta, Feng Gao, Jeffery M Gearhart, Garett Goh, Jonathan M Goodman, Francesca Grisoni, Christopher M Grulke, Thomas Hartung, Matthew Hirn, Pavel Karpov, Alexandru Korotcov, Giovanna J Lavado, Michael Lawless, Xinhao Li, Thomas Luechtefeld, Filippo Lunghini, Giuseppe F Mangiatordi, Gilles Marcou, Dan Marsh, Todd Martin, Andrea Mauri, Eugene N Muratov, Glenn J Myatt, Dac-Trung Nguyen, Orazio Nicolotti, Reine Note, Paritosh Pande, Amanda K Parks, Tyler Peryea, Ahsan H Polash, Robert Rallo, Alessandra Roncaglioni, Craig Rowlands, Patricia Ruiz, Daniel P Russo, Ahmed Sayed, Risa Sayre, Timothy Sheils, Charles Siegel, Arthur C Silva, Anton Simeonov, Sergey Sosnin, Noel Southall, Judy Strickland, Yun Tang, Brian Teppen, Igor V Tetko, Dennis Thomas, Valery Tkachenko, Roberto Todeschini, Cosimo Toma, Ignacio Tripodi, Daniela Trisciuzzi, Alexander Tropsha, Alexandre Varnek, Kristijan Vukovic, Zhongyu Wang, Liguo Wang, Katrina M Waters, Andrew J Wedlake, Sanjeeva J Wijeyesakere, Dan Wilson, Zijun Xiao, Hongbin Yang, Gergely Zahoranszky-Kohalmi, Alexey V Zakharov, Fagen F Zhang, Zhen Zhang, Tongan Zhao, Hao Zhu, Kimberley M Zorn, Warren Casey, Nicole C Kleinstreuer
May 07, 2021
BACKGROUND: Humans are exposed to tens of thousands of chemical substances that need to be assessed for their potential toxicity. Acute systemic toxicity testing serves as the basis for regulatory hazard classification...